Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true...

37
Biochemistry Notes SB1- Relationship between Structure and Function in Cells

Transcript of Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true...

Page 1: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Biochemistry Notes

SB1- Relationship between Structure and Function in Cells

Page 2: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

What is Chemistry?

Chemistry is the science concerned with the composition, structure, and properties of matter, as well as the changes it undergoes during chemical reactions

How does chemistry relate to Biology?

SB1- Relationship between Structure and Function in Cells

Page 3: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Elements

Chemistry in Biology

An element is a pure substance that cannot be broken down

There are over 100 known elements, 92 of which occur naturally.

Each element has a unique name and symbol.

6.1 Atoms, Elements, and Compounds

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 4: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

The Periodic Table of Elements

Chemistry in Biology

Horizontal rows are called periods.

Vertical columns are called groups. Organized by number of protons, and therefore also

organized by properties (groups)

6.1 Atoms, Elements, and Compounds

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 5: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry = study of matter.

6.1 Atoms, Elements, and Compounds

Atoms are the building blocks of matter.

Chapter 6 Chemistry in Biology

Neutrons and protons are located at the nucleus of the atom.

Protons are positively charged particles.

Neutrons are particles that have no charge.

SB1- Relationship between Structure and Function in Cells

Page 6: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Electrons are negatively charged particles that are located outside the nucleus.

Chemistry in Biology

6.1 Atoms, Elements, and Compounds

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 7: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

• Atomic Number: number of protons in the nucleus of an element (atom). In a neutral atom, this is also the number of electrons.

6.1 Atoms, Elements, and Compounds

SB1- Relationship between Structure and Function in Cells

Page 8: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

• Atomic Mass: the number of protons & neutrons in the nucleus of an element (atom).

• Find the neutrons only: • Atomic mass-atomic number=neutrons

• Ex: Carbon Picture

6.1 Atoms, Elements, and Compounds

SB1- Relationship between Structure and Function in Cells

Page 9: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemical Bonds hold atoms, molecules and compounds

together

Chemistry in Biology

Two types of chemical bonds: Covalent bonds

Electrons are shared evenly between atoms

Ionic bonds Atoms are oppositely charged and electrons are

therefore given to the “stronger” atom.

6.1 Atoms, Elements, and Compounds

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 10: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

6.1 Atoms, Elements, and Compounds

Chapter 6

SB1- Relationship between Structure and Function in Cells

A molecule is formed when two or

more atoms join together

chemically.

A compound is a molecule that

contains at least two different

elements.

All compounds are molecules but not all molecules are compounds.

O2

H20

NaCl

N2

CO2

H2

Page 11: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Reactions

A physical reaction does not produce a new substance, but involves a change in the state of matter. Ex: crushing a can, melting

an ice cube. A chemical reaction is the

process by which atoms or groups of atoms in substances are reorganized into different substances. Ex: rusting, combustion

(burning), cooking an egg

6.2 Chemical Reactions

Chemistry in Biology

Chemical reaction

Physical reaction

Chapter 6

Page 12: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemical Equations

Chemistry in Biology

Chemical equations describe the substances in the reaction and arrows indicate the process of change.

Reactants are the starting substances, on the left side of the arrow.

Products are the substances formed during the reaction, on the right side of the arrow.

6.2 Chemical Reactions

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 13: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Example reaction: Glucose and oxygen react to form carbon

dioxide and water. Critical thinking: What biochemical process does

this chemical equation represent???

Chemistry in Biology

6.2 Chemical Reactions

Chapter 6

SB1- Relationship between Structure and Function in Cells

C6H12O6 + 6O2 6C02 + 6H20

Page 14: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

Energy diagrams illustrate the progress and available energy of a chemical reaction. The activation energy

is the minimum amount of energy needed for reactants to form products in a chemical reaction.

Energy of Reactions 6.2 Chemical Reactions

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 15: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

All chemical reactions either take in energy or release energy. Exothermic reactions:

release heat energy. Endothermic reactions:

absorbs heat energy.

Energy of Reactions

6.2 Chemical Reactions

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 16: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

This reaction is exothermic and released heat energy.

The energy of the product is lower than the energy of the reactants.

6.2 Chemical Reactions

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 17: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

This reaction is endothermic and absorbed heat energy.

The energy of the products is higher than the energy of the reactants.

6.2 Chemical Reactions

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 18: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

Enzymes are special proteins that help to speed up chemical reactions by acting as catalyst and lessening the activation energy.

Enzymes

6.2 Chemical Reactions

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 19: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

A catalyst is a substance that lowers the activation energy needed to start a chemical reaction.

Enzymes are biological catalysts.

It does not increase how much product is made and it does not get used up in the reaction.

Enzymes

6.2 Chemical Reactions

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 20: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

The substance acted upon by the enzyme is called the substrate.

The specific location where a substrate binds on an enzyme is called the active site.

6.2 Chemical Reactions- How do they Work???

Chapter 6

Fits together like a lock and key

SB1- Relationship between Structure and Function in Cells

Page 21: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

Enzymes are biological catalysts that speed up reactions in living organisms. Enzymes used for: Photosynthesis Cell Respiration Growth Waste removal DNA replication Movement

Enzymes

6.2 Chemical Reactions

Chapter 6

SB1- Relationship between Structure and Function in Cells

Page 22: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Enzymes in Action

http://www.lpscience.fatcow.com/jwanamaker/animations/Enzyme%20activity.html

SB1- Relationship between Structure and Function in Cells

Page 23: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Organic Chemistry

The study of all compounds containing the element CARBON

6.4 The Building Blocks of Life

Chemistry in Biology Chapter 6

SB1- Relationship Between Structure and Function in Cells

Page 24: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

Carbon compounds can be in the shape of straight chains, branched chains, and rings.

6.4 The Building Blocks of Life

Chapter 6

SB1- Relationship Between Structure and Function in Cells

Page 25: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

What is a macromolecule?

A giant molecule made up of 100’s or 1000’s or smaller units called MONOMERS

Monomers link together to form large POLYMERS

SB1- Relationship Between Structure and Function in Cells

Page 26: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Macromolecules

Chemistry in Biology

Carbon atoms can be joined to form carbon molecules.

Macromolecules are large molecules formed by joining smaller organic molecules together.

Polymers are molecules made from repeating units of identical or nearly identical compounds linked together by a series of covalent bonds.

monomers + monomers + monomers = polymers

6.4 The Building Blocks of Life

Chapter 6

SB1- Relationship Between Structure and Function in Cells

Page 27: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

The 4 types of macromolecules:

CARBOHYDRATES

LIPIDS

NUCLEIC ACIDS

PROTEINS

SB1- Relationship Between Structure and Function in Cells

Page 28: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

CARBOHYDRATES Made up of C,H,O

Used as main source of energy

Two types:

Sugars: quick source of energy

Monosaccharide-simple sugar, disaccharide-2 sugars

Ex: glucose, lactose, fructose, sucrose

Starches: many sugars linked together, source of energy breaking down slower. Polysaccharides.

Used by plants for energy storage

Ex: potatoes, pasta, bread, grains SB1- Relationship Between Structure and

Function in Cells

Page 29: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Starch

Glucose

Section 2-3

Figure 2-13 A Starch

Go to Section:

SB1- Relationship Between Structure and Function in Cells

Carbohydrates can provide structure – such as cellulose!

Page 30: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

Lipids

Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and

fatty acids

A triglyceride is a fat if it is solid at room temperature and an oil if it is liquid at room temperature. Ex: fats, oils, waxes, phospholipids

6.4 The Building Blocks of Life

Chapter 6

SB1- Relationship Between Structure and Function in Cells

Page 31: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

Lipids that have tail chains with only single bonds are called saturated fats.

Lipids that have at least one double bond in the tail chain are called unsaturated fats.

Fats with more than one double bond in the tail are called polyunsaturated fats.

6.4 The Building Blocks of Life

Chapter 6

SB1- Relationship Between Structure and Function in Cells

Page 32: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

LIPIDS

Made up mainly of C & H

Used to store energy, insulation & protection

Usually not soluble in water

Saturated: has maximum number of H bonds, usually solid at room temperature

Unsaturated: at least one double bond, usually liquid

SB1- Relationship Between Structure and Function in Cells

Page 33: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

Proteins

A compound made of small carbon compounds called amino acids

Amino acids are small compounds that are made of carbon, nitrogen, oxygen, hydrogen, and sometimes sulfur.

6.4 The Building Blocks of Life

Chapter 6

SB1- Relationship Between Structure and Function in Cells

Page 34: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

The other three bonds are with an amino group (–NH2), a carboxyl group (–COOH), and a variable group (–R).

6.4 The Building Blocks of Life

Chapter 6

SB1- Relationship Between Structure and Function in Cells

Page 35: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

PROTEINS Made up of C,H,O,N

Made up of groups called amino acids (20 in nature)

proteins have a large variety of sizes & shapes

If the shape changes, it becomes a new protein

Ex: when you boil an egg, the protein changes color, shape

Found in muscles, cell membrane SB1- Relationship Between Structure and

Function in Cells

Page 36: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Chemistry in Biology

Nucleic acids are complex macromolecules that store and transmit genetic information.

Nucleic acids are made of smaller repeating subunits called nucleotides, composed of sugar, phosphate and nitrogen base.

6.4 The Building Blocks of Life

Chapter 6

SB1- Relationship Between Structure and Function in Cells

Page 37: Biochemistry Notes · Chemistry in Biology Lipids Made mostly of carbon and hydrogen No true monomers, but consist of glycerol and fatty acids A triglyceride is a fat if it is solid

Nucleic Acids

Made up of H,O,N,C & P

Store and transmit genetic information

Made up of nucleotides

Two types: DNA & RNA

SB1- Relationship Between Structure and Function in Cells