Bell RingerBell Ringer1. Identify the organelle that stores our genetic

information

2. Yesterday we learned that the BRCA1 protein helps prevent cells from becoming cancerous. What is the effect of having a mutation like Theresa’s in the BRCA1 gene?

How is our genetic information stored?

Levels of Genetic Organization

Largest

Smallest

Nucleus Organelle that contains the DNA

How is our genetic information stored?Levels of Genetic Organization

Largest

Smallest

Nucleus Organelle that contains the DNA

Chromosome Large coiled bundles of DNA

How is our genetic information stored?Levels of Genetic Organization

Largest

Smallest

Nucleus Organelle that contains the DNA

Chromosome Large coiled bundles of DNA

Gene section of DNA that codes for a certain protein and leads to a certain trait

How is our genetic information stored?Levels of Genetic Organization

Largest

Smallest

Nucleus Organelle that contains the DNA

Chromosome Large coiled bundles of DNA

Gene section of DNA that codes for a certain protein and leads to a certain trait

Nucleotide/ Base

The building blocks of DNA (A, T, C, & G)

How is our genetic information stored?

C--

T--

G--

T--

A--

Base Pair RuleA + T

(Adenine + Thymine)C + G

(Cytosine + Guanine)

Is it a Chromosome, Gene, Is it a Chromosome, Gene, or Nucleotide?or Nucleotide?

Circle one and explain how you know.

Yesterday we learned about a segment of nucleotides that serves as instructions about how to make the BRCA protein. This can be called a… chromosome gene nucleotide

How do you know?

A scientist used an electron microscope and a laser to slice a nucleus in half and observe its contents. He saw 23 bundled structures inside. These can be called… chromosomes genes nucleotides

How do you know?

These lines point to… chromosomes

genes nucleotides

How do you know?

A-T-C-C-G-AA-T-C-C-G-A

DNA Sequence

determines

Protein Made

determines

Trait

Why do we look the way we do?

A-T-C-C-G-AA-T-C-C-G-A

DNA Sequence

determines

Protein Made

determines

Trait

Why do we look the way we do?

So does everyone have the same So does everyone have the same sequencesequence of DNA? of DNA?

Crazy Fact: Crazy Fact: Each one of your cells Each one of your cells has the EXACT same sequence of has the EXACT same sequence of DNADNA

Nerve Cell Stomach Cell

How is it possible?!How is it possible?! Genes that are needed in a cell Genes that are needed in a cell are are activatedactivated (turned on) and (turned on) and genes that are not needed are genes that are not needed are deactivated deactivated (turned off).(turned off).

Nerve Cell Stomach Cell

Stop and JotDNA is made up 4 building blocks- A, T, C, G. Is the

sequence (order) of these nucleotides the same in your cells as they are in the person sitting next to you? Why or Why not?

Is the sequence of nucleotides the same in your eye cell as it is in your liver cell? Explain why or why not.

Partner Practice1. Which statement describes one

characteristic of this molecule?(1) It is the template for the replication of

genetic information.(2) Organic catalysts are made up of these

molecules.(3) It is different in each cell of an organism. (4) Cell membranes contain many of these

molecules.

Partner Practice2. Which diagram represents the relative sizes of the

structures listed below?

Partner PracticeA human liver cell is very different in structure and

function from a nerve cell in the same person. This is best explained by the fact that

(1)different genes function in each type of cell (2) different DNA is present in each type of cell(3) liver cells contain fewer chromosomes than

nerve cells (4) different DNA is present in each type of cell