Guided by :Dr. Sunita AmrutheshHOD & Prof. BIDSH, Patna

Presented by :Dr. BhavnaPG 1st yrBIDSH , Patna

Ayurvedic Drugs in DentistryTheir Pharmacology & Benefits

Contents Introduction Classification of plants

based on Pharmacological actions

Dravya guna ( Ayurvedic Pharmacology of Drugs )

Ayurvedic Drugs in Dentistry

Conclusion Reference

Introduction

Ayurveda a system, which uses the inherent principles of nature, to help maintain health in a person by keeping the individual's body, mind and spirit in perfect equilibrium .It is an intricate medical system that originated in India about 5000 years ago.

Dravyaguna- pharmacology of ayurvedic medicines

More than 600 herbal formulas and 250 single plant drugs are included in the "pharmacy" of Ayurvedic treatments.

Successfully used in dentistry as tooth cleaning, anti-inflammatory, anti-analgesics and antimicrobial plaque agents..

Classification

Antiulcerogenic

Anti inflammatory

Anti microbial

Anti oxidant

Analgesic Immuno

modulatory

Dravya-gunaPharmacology of Ayurvedic drugs

1)Rasa (Taste) Herbs are classified as possessing one or more of the six tastes

2) Vīrya (Hot or Cold Potency) Herbs are classified as hot, warm, cool, or cold

3) Vipāka (Post Digestive Taste) Herbs all have a certain taste in the small intestine , once the herbs have been processed in the stomach

4) Dosha Parināma (Effect on the Three Doshas) All herbs will have a tendency to increase or decrease the individual doshas

5) Dhātu Parināma (Effects on the Organs) e.g.brahmi calms the mind and clears heat and repressed anger from the heart and liver.

6)Srotamsi Parināma (Effect on the Systems in the body) : e.g. cinnamon tends to effect the digestive system,

7 Roga Parināma (Effect on particular dis-eases or conditions) e.g. Neem is used to treat infections, rashes, parasites, fungus, liver disorders, toxic blood, diabetes, heat, high pitta, and kapha, etc.

8)Karma or Guna (Herbal Actions)- “Karma” means “action” & “guna” means “quality.” Herbs are further categorized according to specific qualities or actions: e.g. expectorant herbs clear kapha and plegm from the lungs, stomach, sinuses, and throat.

9) Prabhāva (Special Action) -Prabhaava denotes special and often unexpected qualities of various herbs.

Ayurvedic DrugsPharmacology

& Benefits

Neem (Azadirachta indica)

Ayurvedic Properties

• Taste ( Rasa): Tikta( bitter), kashaya

• Property (Guna): Laghu

• Potency (Veerya): Sheeta

• Post digestive effect (Vipaka): Katu

• Actions (Karma): Reduces Kapha & Pitta

• Indications : Dentrifice, dental caries , root canal irrigant, gingivitis, periodontitis

CHEMICAL COMPOSITION

Phenols, unsaturated sterols, triterpenes and saponine Phenolic diterpenoids, limonoids), c-secomeliacins, c-secolimonoids ,polysachharides , azadirachtin

Pharmacological Activities

anti inflammatory

Anti pyeretic anti arthritic hypoglycemic anti fungal anti bacterial

Amalaki ( Phyllanthus emblica) Ayurvedic Properties

• Taste (Rasa): Astringent (Kashaya), sour (Amla),

sweet (Madhura), pungent (Katu) and bitter (Tikta)

• Property (Guna): Mobile (Sara), dry (Ruksha)

• Potency (Veerya): Cold (Sita)

• Post digestive effect (Vipaka): Sweet (Madhura)

• Actions (Karma): Alleviates vitiation of all 3 Doshas (Tridosha hara)

• Indications : anaemia , diabetes, Eye diseases, Scurvy, Mouth ulcers,

CHEMICAL COMPOSITION

Vitamin C (L- ascorbic acid), gallic acid, ellagic acid, phyllemblic acid, emblicol. Alkaloides ie., phyllantidine, phyllantine. Pectin and minerals.Pharmacological Activities Anti inflammatory Anti cancer Anti ulcer Anti oxidant Enhances immunity

Ardraka ( Zingiber officinale)

Ayurvedic Properties• Taste (Rasa): Pungent (Katu)

• Property (Guna): Light (Laghu),sharp (Tikshna)

• Potency (Veerya): Hot (Ushna)

• Post digestive effect (Vipaka): Sweet (Madhura)

• Actions (Karma): Alleviates vitiated Kapha and Vata doshas (Vata- Kapha hara)

• Indications : cough, fever, arthritis, nausea , Oral thrush, xerostomia, tooth ache

CHEMICAL COMPOSITION

Gingerols, α-zingiberene, β-sesquiphellandrene, curcumene, anhydro-gingerols, paradols, gingerdiols, gingerdiacetates, gingerdiones, 6-gingersulfonic acid, gingerenones, diarylhepatanoids, diterpenes, gingerglycolipids A, B & C .Pharmacological Activities

Anti oxidant Anti emetic Anti inflammatory Anti hyperglycemic Anti tumorigenic

Haldi ( Curcuma longa)Ayurvedic Properties

Taste (Rasa): Pungent (Katu), Tikta ( Bitter)

Property (Guna): Ruksha ( dry)

Potency (Veerya): Hot (Ushna)

Post digestive effect (Vipaka): Katu ( Pungent)

Actions (Karma): supresses all the tri doshas ( vata, pitta ,kapha)

Indications : diabetes, anemia, urticaria, Oral sub mucous fibrosis, Periodontal diseases

CHEMICAL COMPOSITION

flavonoid curcumin (diferuloylmethane) and various volatile oils, including tumerone, atlantone, and zingiberone.Pharmacological Activities anti oxidant anti inflammatory anti fungal anti viral

Clove (Syzygium aromaticum)Ayurvedic Properties

• Taste (Rasa): Pungent (Katu), Tikta ( Bitter)

• Property (Guna): laghu, snigdha

• Potency (Veerya): Sheet (cold)

• Post digestive effect (Vipaka): Katu ( Pungent)

• Actions (Karma): balances Kapha and Vata

• Indications : halitosis, toothache, gingival diseases, dental caries

CHEMICAL COMPOSITIONThymol, Eugenol, Eugenyl acetate, Caryophyllene oxide, Benzene-1-butylheptyl, Hexadecanoic acid, Vitamin E acetate, Guaiol

Pharmacological Activities Anti oxidant Anti septic Anti microbial Anti viral

Conclusion

• The natural phytochemicals could offer an effective alternative to antibiotics and other modern drugs

• Represent a promising approach in prevention and therapeutic strategies for dental caries and other oral infections

References Amruthesh S. Dentistry and Ayurveda-I. Indian J Dent Res 2003;14:1-5

Amruthesh S. Dentistry and Ayurveda-II. Indian J Dent Res 2003; 14: 132-40.

Amruthesh S. Dentistry and Ayurveda-III. Indian J Dent Res 2007; 18:112-9.

Amruthesh S. Dentistry and Ayurveda-IV: Classification and management of common oral diseases. Indian J Dent Re 2008; 19:52-61.

POTENTIALInternational Journal of Phytopharmacology, 1(2), 2010, 57-63.Some phytochemical, pharmacological and toxicological propertiesof ginger (Zingiber officinale Roscoe): A review of recent researchBadreldin H. Ali a,*, Gerald Blunden b, Musbah O. Tanira a, Abderrahim Nemmar cFood and Chemical Toxicology 46 (2008) 409–420

CCRAS Publication. Data base on Indian Medicinal Plants. Page No. 256-284Kausik Biswas, Ishita Chattopadhyay, Ranajit K. Banerjee* andUday Bandyopadhyay Biological activities and medicinal properties ofneem (Azadirachta indica)

ReferencesSandeep A. Lawande. Therapeutic applications of turmeric (Curcuma longa) in dentistry: A promising future. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.)2013, February; 27(27): 586-591. (Article no 28)

M. AKRAM1, SHAHAB-UDDIN1, AFZAL AHMED2, KHAN USMANGHANI3,ABDUL HANNAN3, E. MOHIUDDIN4, M. ASIF5 CURCUMA LONGA AND CURCUMIN: A REVIEW ARTICLE

Ekta Singh, Sheel Sharma, Ashutosh Pareek, Jaya Dwivedi, Sachdev Yadavand Swapnil Sharma Phytochemistry, traditional uses and cancer chemopreventive activity of Amla (Phyllanthusemblica): The Sustainer. Journal of Applied Pharmaceutical Science 02 (01); 2011: 176-183 SRIVASUKI K.P. NUTRITIONAL AND HEALTH CARE BENEFITS OF AMLA Journal of Pharmacognosy ISSN: 0976-884X & E-ISSN: 0976-8858, Volume 3, Issue 2, 2012, pp.-147-151 Charaka Samhita Handbook on Ayurveda Vol 1