Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.

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Axon targeting in the Drosophila visual system
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Transcript of Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.

Page 1: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.

Axon targeting in the Drosophila visual system

Page 2: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.

Adult compound eye Eye imaginal disc

Page 3: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.

Recruitment of photoreceptors

Page 4: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.
Page 5: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.

Repo: glia

24B10

gigamesh mutant

Requirement of gish in eye epithelium, but not glial cells or differentiated R cells

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Regulation of retinal basal glial cell migration

Page 7: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.

Hh and Spitz are transported in R axon to lamina for proliferation (Hh) and differentiaiton (Spitz)

Page 8: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.
Page 9: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.

Brakeless is required for R1-6 axon targeting

Brakeless is a nuclear Zn finger protein

Page 10: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.
Page 11: Axon targeting in the Drosophila visual system. Adult compound eye Eye imaginal disc.

Glia cells are required for R1-6 axon targeting

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Nonstop controls glial cell migration

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Nonstop: Ub protease, required in glial cellsJab1/CSN5: COP9 subunit, required in R cells for glial cell migration

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LAR in R7 target selection

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GEF

S/T kinase

AdaptorN-CAM