Anmar Nassir, Assistant Prof, Um Al-Qura Univ Hasan Farsi, Prof, KAUH Ammar Dehlawi, Teach assist Um...
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Transcript of Anmar Nassir, Assistant Prof, Um Al-Qura Univ Hasan Farsi, Prof, KAUH Ammar Dehlawi, Teach assist Um...
Anmar Nassir, Assistant Prof, Um Al-Qura Univ
Hasan Farsi, Prof, KAUH
Ammar Dehlawi, Teach assist Um Al-Qura Univ
Little is known about prostate cancer in Saudi Arabia.
National Cancer Registry data GU Ca: 9.2% in KSA, vs 24.1% USA Prostatic CA is X 50 lower than in USA The most common GU CA in KSA is
bladder, followed by the prostate, kidney, and testicular cancer.
Our aim is : to identify the pattern of PSA values in our
population. to identify the high risk patients: candidate for
TRUS biopsy
Between October 2002 and November 2007, all PSA values ordered at KFSH& RC in Jeddah were studied.
Data collected: patient's age, total PSA, free to total ratio, PSA velocity
The overall average age 63.8 (+/- 11.8 SD).
A total of 4210 specimen of PSA were analyzed for 2181 patients.
PSA ng/ml< 2.5< 4 4-10 >10
% of pt
Free to total PSA ratio for PSA of 4-10
< 11 < 18 < 22 < 25
no.
%
For pts between 4-10 % according to cut points
PSA velocity was studied in 2803 PSA samples for 801 patients, with an average of 3.5 samples for each
patient.
Patients PSA progression
In the Eastern region of SA: PSA screening of 1192 6.9 % indicated for TRUS Bx Only 75 % agreed for Bx CA in 14 only = 1.17%
In the western region: Out of 45 patients underwent TRUS
guided biopsy; cancer of the prostate was detected in 13 (28.8%).
7.6% in patients presented with abnormal DRE alone
15.3% in the group with elevated PSA but normal DRE (stage T1c).
21.4% PSA was elevated to 4-10 ng/ml
40% PSA to10-20 ng/ml 100% PSA > 20 ng/ml
21.4% PSA was elevated to 4-10 ng/ml 40% PSA to10-20 ng/ml 100% PSA > 20 ng/ml
% of CA-- 1.64 % 2.44 %
PSA ng/ml< 2.5< 4 4-10 >10
% of pt76.8858.26.1
All patients Patients to FM
PSA no. % no. %
< 4 1871 86% 162 87.5
4 to < 10 178 8.20% 12 6.5
> or = 10 132 6.05% 11 5.9
2181 100% 185 99.9
Sensitivity of CA detection: PSA between 4-10 vs <4 ng/mL:
79% for levels between 4 and 10 ng/mL. 11% at levels below 4 ng/mL
In a large prospective screening study 47% among men with a PSA velocity >
0.75 ng/mL per year 11% among men with a PSA velocity <
0.75 ng/mL per year
At KFSH & RC Jd 88 patients came back +ve for Prostate cancer.
84/2181 = 4%
عن معاذ بن جبل ، أنهم خرجوا مع رسول الله صلى الله عليه وآله ... وسلم عام تبوك
إنكم ستأتون غدا ، إن شاء الله عين تبوك ، وإنكم لن تأتوها قال: "حتى يضحى النهار ، فمن جاءها فال يمس من مائها شيئا حتى
“آتيفجئناها ، وقد سبقنا إليها رجالن ، والعين تبض بشيء من ماء،
هل مسستما من مائها شيئا؟فسألهما رسول الله:" " . فقاال : نعم
. قال لهما ما شاء الله أن يقول...ثم غرفوا بأيديهم من العين ، قليال قليال . حتى اجتمع في شيء ، ثم غسل رسول الله صلى الله عليه وسلم ، فيه وجهه
ويديه . ثم أعاده فيها ، فجرت العين بماء كثير . . فاستقى الناس
يوشك يا معاذ إن ثم قال رسول الله صلى الله عليه وسلم : " ” طالت بك حياة، أن ترى ما هاهنا قد ملئ جنانا
واإلمام مسلم في صحيحه 331مالك في الموطأ 4327
By non By urologist
age
SD
No. %
< 4
4-10
> 10
> 20
PSA By non Urologists by Urologists
# % # %
< 4
4-10
> 10
> 20
All patients Patients to FM From out side
PSA no. % no. % No. %
< 4
4 to < 10
> or = 10
> or = 20