AgION Technologies SilverClene24 Competitive Analysis: Healthcare Industry.

AgION Technologies

SilverClene24

Competitive Analysis:

Healthcare Industry

© AgION Technologies, Inc., 2007 www.agion-tech.com 2

Healthcare awareness

¨ 5,800 U.S. hospitals; 976,000 beds¨ Infection rate in U.S.: 7% of all patients

• 2 million patients annually• 100,000 patient deaths/year• Problem worsening as bacterial resistance to antibiotics

spreads

¨ Fourth leading cause of death in America¨ Direct costs in excess of $5 billion/year

PROBLEM: Healthcare Associated InfectionsAnd Nosocomial Infections

Healthcare institutions looking for ways to reduce HAI’s


Healthcare Disinfectant Applicable Areas

Healthcare Disinfectant Application Areas SilverClene24 Market?

Surgical Instrument Disinfection NO

High Level Disinfectants (HLD-endoscope processing, etc.) NO

Skin Care Antiseptics (Surgical Sites and Hand Washing) NO

Environmental Surface Disinfection YES


Hard Surface Disinfectants

¨ Surface Disinfectant Market $75M (Ready To Use)

30%

20%25%

10%

15%PDI

Eco/Huntington

Steris

Metrex

Other


Hard Surface Disinfectant Products

Eco/Hunt• Asepticare TB II• Asepti-Wipe II• Hi-Tor• Tor TB

PDI• SaniCloth HB• SaniCloth Plus• Super SaniCloth

Metrex• Cavicide• Caviwipes• Envirocide

Steris• Staphene• Vesphene• Coverage• TBQ


Toxicity Levels

¨ HSD’s are assigned toxicity levels 1 - 4 (1 being most toxic)

Tox level 1 “Danger” *Skull and Crossbones Required

Tox level 2 “Warning”

Tox level 3 "Caution"

Tox level 4 Normally does not require caution label

HSD Toxicity Level

Steris 1

ECO/Hunt 2

PDI 3

Metrex 3

SilverClene24 4

SilverClene24 is a level 4* Disinfectant*Lowest Possible Toxicity Level


Hard Surface Disinfectants

¨ Product Types• Alcohol• Quaternary ammonium salts (quats)• Phenols• Bleach (Chlorine)• Peroxides• Aldehydes (Glutaraldehyde/OPA/Cidex)• Citrus/Silver Ion


Competitors and Active Ingredients

YES YES NO YES NO NO NO

YES YES NO NO NO NO NO



NO NO NO NO NO NO YES

Steris

Eco/Hunt

Clorox 409

PDI

Metrex

Quats AlcoholBleach

Phenols Peroxides Aldehydes

Environmental Surface Disinfection

Ionic Silver

Agion

(Chlorine)


Comparison of Competitive Technologies

Quats AlcoholBleach

(Chlorine)Phenols Peroxides Ionic Silver

Non Flammable X X X X

Non Corrosive X X X

No Irritating Fumes

X X

No Skin Irritation X

Stable in Solution X X X X X

Toxicity Category # 1, 2 or 3 1, 2 or 3 1, 2 or 3 1, 2 or 3 1, 2 or 3 4

Significant Residual Activity

X X

* Toxicity Levels 1 – 4 with 4 being least toxic


Surface Disinfectants

Parameter SilverClene24 PDI Eco/HuntingtonClorox 409

Steris Metrex

Composition Naturally-occurring

Volatile synthetic chemicals, Quats

Synthetic organics Volatile synthetic chemicals, Quats

Synthetic organics

Irritating fumes/odors

No Yes Yes Yes Yes

Longevity Up to 24 hours 10 mins. 10-30 minutes 10 minutes 10-30 minutes

Staining/ discoloration

No Possible Possible No Possible

Antibiotic resistance

No Possible Possible Possible Possible

Protects against re-contamination

Yes No No No No

Consumer perception

Positive Negative Negative Negative Negative

Competitive Technologies Comparison


SilverClene24 Efficacy

Pseudomonas aeruginosa 30 seconds

Staphylococcus aureus 30 seconds

Salmonella choleraesuis 30 seconds

Listeria monocytogenes 30 seconds

Vancomycin resistant Enterococcus faecium (VRE) 2 minutes

Methicillin resistant Staphylococcus aureus (MRSA) 2 minutes

Escherichia coli 0157:H7 2 minutes

Trichophyton mentagrophytes (Athlete’s Foot Fungus) 10 minutes

HIV type 1- Strain HTLV IIIB 1 30 seconds

Herpes Simplex Type 1 VR-733 F(1) Strain 1 minute

Influenza A VR-5 44, Hong Kong strain 10 minutes

Rhinovirus R37 VR-1147, Strain 151-1 10 minutes

Polio Type 2, VR-1002, Lansing Strain 10 minutes

AgION® SilverClene 24™ killed the following organisms (AOAC protocols) Association of Analytical Chemists - sets standards for analytical results obtained from scientific analysis


SilverClene24 Cavicide SaniCloth Vesphene II AspetiCare

Pseudomonas aeruginosa 30 seconds 3 minutes 2 minutes 3 minutes 10 minutes

Staphylococcus aureus 30 seconds 3 minutes 2 minutes 10 minutes 10 minutes

Salmonella choleraesuis 30 seconds 3 minutes 2 minutes 10 minutes 10 minutes

Listeria monocytogenes 30 seconds 2 minutes 3 minutes

VRE 2 minutes 3 minutes 2 minutes

MRSA 2 minutes 3 minutes 2 minutes 10 minutes

Escherichia coli 0157:H7 2 minutes 2 minutes 10 minutes

Trichophyton mentagrophytes (Athlete’s Foot Fungus)

10 minutes 3 minutes 10 minutes 5 minutes

HIV type 1- Strain HTLV IIIB 1 30 seconds 2 minutes 2 minutes 10 minutes 30 seconds

Herpes Simplex Type 1 VR-733 F(1) Strain

1 minute 10 minutes 30 Seconds

Influenza A VR-5 44, Hong Kong strain 10 minutes 2 minutes 30 seconds

Rhinovirus R37 VR-1147, Strain 151-1 10 minutes 2 minutes 3 minutes

Polio Type 2, VR-1002, Lansing Strain 10 minutes 3 minutes

Mycobacterium tuberculosis var: bovis (BCG) (TB)

3 minutes 2 minutes 10 minutes 6 minutes

HBV 2 minutes 2 minutes

HCV 2 minutes 2 minutes

Competitor Efficacy


Healthcare Promotions


Natural Disinfectant and Virucide


SilverClene24

¨ Distributor – Bio Shield Technologies

¨ Company Focus - Natural antimicrobial solutions for healthcare industry.

¨ Offers Antimicrobial solutions for virtually every healthcare need.

Phone 717-489-1728 Fax: [email protected]

www.bioshieldtech.com

mailto:[email protected]

AgION Technologies SilverClene24 Competitive Analysis: Healthcare Industry.

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