ADInstruments Product Overview - Animalabanimalab.eu/sites/all/pliki/produkty-dopobrania/ad...of...
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ADInstruments Product Overview Applications • Cardiovascular pressures • Ventricular pressure-volume • Blood flow and cardiac output • Isolated tissue and dose response • Isolated perfused organs • ECG and HRV • Intracellular recording • Extracellular recording • Evoked potentials • Respiration and exercise physiology Complete solutions for life science research ADInstruments research systems offer flexible, all-in-one solutions for your research, including PowerLab for data acquisition and LabChart soſtware for comprehensive data analysis. Whatever signals you want to measure, an ADInstruments system can be customized to record, display and analyze your experimental data with ease and accuracy. Fast tracking research Designed for life sciences, LabChart will help you streamline your analysis with specialist modules such as ECG Analysis, Blood Pressure, Dose Response, Spike Histogram, Peak Analysis and Video Capture that bring all the calculations you need into one place. Create your complete solution Tailor a complete solution for your research application. Our dedicated team can help you choose from a range of signal conditioners and application-specific instruments, transducers and accessories. Take advantage of global support When your research takes you places, we are there to help. Our global network of offices and distributors covers more than 80 countries, offering specialist support, technical advice and a range of workshops and training courses. Products Overview Brochure 2015-A4 V1-0
Transcript of ADInstruments Product Overview - Animalabanimalab.eu/sites/all/pliki/produkty-dopobrania/ad...of...
ADInstruments Product Overview
Applications• Cardiovascular pressures
• Ventricular pressure-volume
•Bloodflowandcardiacoutput
• Isolated tissue and dose response
• Isolated perfused organs
• ECG and HRV
• Intracellular recording
• Extracellular recording
• Evoked potentials
• Respiration and exercise physiology
Complete solutions for life science researchADInstrumentsresearchsystemsofferflexible,all-in-onesolutionsforyourresearch,includingPowerLabfordataacquisitionandLabChartsoftwareforcomprehensivedataanalysis.Whateversignalsyouwanttomeasure,anADInstrumentssystemcanbecustomizedtorecord,displayandanalyzeyourexperimentaldatawitheaseandaccuracy.
Fast tracking researchDesignedforlifesciences,LabChartwillhelpyoustreamlineyouranalysiswithspecialistmodulessuchasECGAnalysis,BloodPressure,DoseResponse,SpikeHistogram,PeakAnalysisandVideoCapturethatbringallthecalculationsyouneedintooneplace.
Create your complete solutionTailoracompletesolutionforyourresearchapplication.Ourdedicatedteamcanhelpyouchoosefromarangeofsignalconditionersandapplication-specificinstruments,transducersandaccessories.
Take advantage of global supportWhenyourresearchtakesyouplaces,wearetheretohelp.Ourglobalnetworkofofficesanddistributorscoversmorethan80countries,offeringspecialistsupport,technicaladviceandarangeofworkshopsandtrainingcourses.
ProductsOverviewBrochure2015-A4V1-0
Signal conditioners and instrumentsADInstrumentsmanufacturesawiderangeofsoftwarecontrolledpreamplifiersthatareautomaticallyidentifiedandconfiguredbyPowerLab.Allsettingsareautomaticallystoredwithdatafilesforeasyrepeatingofexperiments.
Precision data acquisition
hardware
PowerLabistheoriginalhigh-performancedigitaldataacquisitiondevice,citedinmorethan20,000researchpapersinpeer-reviewedjournals.PowerLabsystemsforresearchprovidethefullutilityofamulti-channel,real-timechartrecorder,polygraph,XYplotter,digitalvoltmeterandstorageoscilloscopewiththebenefitsofeasydatahandling,highresolution,andvariablesamplingspeeds.
PowerLab data acquisition units provide:• 16Bitresolutiononallgainranges
• Variablesamplingandonlinecomputationspeedsofupto200000s/sperchannel(400kHzaggregateacrossallchannelsor2x200kHzontwochannels)
• Fastprocessorforreal-timedataacquisitionwithout data loss
• Integratedpodportsforwideramplifierandtransducer choice
• Digital inputs and outputs for external instrument control and triggering
• AC/DCcoupledinputs
• Independent stimulator outputs
• High-pass,low-passandanti-aliasingfilters
• Availablein4,8or16channels
• SuppliedwithLabChartsoftware
PowerLabissimpletosetup,connectingdirectlytoWindowsandMacintoshcomputersviaUSBport,andisautomaticallydetectedbyLabChart.
Transducers and accessoriesWeofferanextensiveselectionofinstruments,transducersandaccessoriesmadebyADInstrumentsandworld-leadingbrands.ProductsarefullycompatiblewithPowerLabrecordersandsignalconditioners.
World-leading analysis software
WithLabChartanalysissoftware,youcanrecordanddisplayyourdatainrealtime,performingonlinecalculationsathighsamplingrates,givingyoufullcontrolofyourresearch.Recordupto32channelsofrawdataandchoosefromLabChart’srangeofsophisticatedAdd-Onsthatarepurpose-builtforsignalsspecifictolifescience,includingcardiovascular,respiratory,bloodpressure,neuronalanddoseresponsedata.LabChartissimpletouseandsuitableforabroadrangeofsignaltypes.
Dose Response Generatesdoseresponsecurves,EC50valuesandadditionalparameters
Metabolic Provides real-time measurements of parameters such as VCO2,VO2,VE and RER
Blood Pressure Automaticallydetects,analyzesandreportsparametersfromarterialorventricularpressurerecordings
SpikeHistogram Detects,discriminatesandanalyzesextracellularspikeactivitygeneratingarangeofplotsandstatistics
ECG Analysis Detectsandreportstheonset,amplitudeandintervaltimesofPQRSTfromhumanandanimalECGsignals
Cardiac Output CalculatescardiacoutputfromaLabChartrecordingofathermodilutioncurvemeasuredinanimals
HeartRateVariability DisplaysandanalyzesvariationintheintervalbetweenheartbeatsinhumanandanimalECG
Video Capture AllowsthesynchronizedrecordingandplaybackofaQuickTimemovieandLabChartdatafile
Peak Analysis Automaticdetectionandanalysisofmultiple,butnotoverlapping,signalwaveformsfromrecording
DMTNormalization Calculatesandstandardizesoptimalvesselpretensionconditionsusingthewiremyograph
PVLoop Analyzesleftventricularpressureandvolumedata,calculatesloopareaandawiderangeofhemodynamicparameters
Use LabChart to:• RecordfrommultiplePowerLabsanddevices• Previewandoptimizerecording• Import and export data easily• Annotate data with comments• Convert raw data into useful units• Automate recording and analysis tasks• Change recording settings in seconds• Recall data and experimental settings• Generatecustomizedstimulusoutputs• SpeedupanalysiswithLabChartModules
Specialized analysis with Add-On modules GetthefullsuiteofmoduleswithLabChartPro(somemodulesarenotavailableonMac).Rangeincludes:
LabChartReaderisdownloadablesoftwarethatletsyoushare yourLabChartdatafileswithcolleagues,publishersandstudents. ItenablesanyonetoopenandviewLabChartfilesandincludesanumberofLabChartanalysisanddisplayfeatures.
Research applications
Cardiovascular pressureMikro-Tip BP Foundation SystemProvidestheessentialtoolsformeasuringbloodpressureinsmallandlargeanimals.Includesthelow-drift,highimpedanceinputBridgeAmp,compatiblewithhigh-fidelityMikro-Tip®BPcathetersforresearch,availableexclusivelyfromADInstruments.ThecathetersoperateseamlesslywithLabChart’sBloodPressureModuletodeterminesystolicanddiastolicpressures,dichroticnotch, dP/dtandmore.
Mikro-Tip pressure-volumeSimultaneouslymeasurepressureandvolumeinlargeandsmallanimalswiththeMPVSUltraFoundationSystemandMillarMikro-Tip®PV catheters(selectedseparately).SuppliedwithLabChart’sPVLoopModuleforautomatedcalculationofsystolicanddiastolicpressures, strokevolume,COandmore.Singleandmulti-segmentMikro-TipPVcatheterssuitableforuseinanimals16gandlargeraresuppliedinarangeofsensorsizesandelectrodeconfigurations.Alsosuitableforuseinthedigestiveandreproductivesystems(i.e.bladder,uterus).
Fluid-filled blood pressure transducersDeterminearterialandvenousbloodpressureusingtherangeoffluid-filledpolyethylene,pressuretransducersforusewithsmallandlargeanimals.The transducers are ideal for use with ADInstruments Bridge Amps or the electrically isolated BP Amp thatprovidesBPreadingsinmmHg.TheBPAmpissuitableforusewithhumansubjects.
Non-invasivebloodpressure(NIBP)Human NIBP SystemMonitortrendsinbloodpressurecontinuouslyandnon-invasivelyinhumans.Fingercuffswitchingallowslongsamplingperiodswithminimaldiscomforttosubjects.Providesareconstructedarterialpulsewaveformbasedonafingercuffmeasurement.Cuffsavailableinavarietyofsizes.BasedonFMStechnology.
Animal NIBP SystemDetectsintermittentpressure/pulseforcalculationofsystolicpressureinmiceandrats.Interchangeableautomatedtailandcufftransducersaresupplied.
Blood flow and cardiac outputInvasive measurementsMeasurearterialorvenousflowwithTransonicFlowSystemsandTransonicFlowprobes(availableseparately).Withminimalsignaldriftandattenuation,flowprobesareappropriateforacuteandchronicstudies.Arangeofsizessuitableformiceandlargeranimalsareavailable,aswellasinline/clamp-onsensorsfortubingapplications.
Blood perfusionContinuouslymonitorbloodandperfusionofmicrovascularbedsandrapidlycalculateCardiacOutput(mL/min)withLaserDopplerFlowmetry(LDF)probesandtheBloodFlowMeter(secondanalogoutputcorrectingforBSC).Suitablefor monitoring circulation during surgery and drug or cardiovascularstudies,LDFprobesforskin,muscleandorgansareavailable.
Get a complete solution for applicationsincludingNIBP, bloodflowandcardiacoutput,isolatedtissue,isolatedheart,biopotentials, electrophysiology, microneurography, psychophysiology andmanymore.
Complete research systems
Multi-Channel Bio Amps8or16channelbioampscanbeusedwithbothchestandresuableelectrodesfordifferentialEEGormultiplebiopotentialmeasurementinasinglesubject.AlsocompatiblewithEEGcaps(availableseparately).
Animal Bio AmpLow-noise,high-gaindifferentialBioAmpsuppliedwithmicro-hookelectrodes.Compatibleneedleorspringclipelectrodes areavailableseparately.
ECG Switch BoxFor mechanical selection of standard lead configurations(10standardleadwires).Idealforvector cardiography as a low cost option for thosewithonlyasingleordualbiotogetafull 12leadECG.TheECGSwitchBoxgivesdirect measurementofleadsI,II,III,aVF,aVL,aVR andV1toV6.
Research applications
Biopotentials ElectricallyisolatedBioAmpsareoptimizedforrecordinghumanandanimalECG,EMG,EEG,ERG,EOG,visualevokedcorticalresponseandmore.PerformpowerfultimeandfrequencydomainanalysisusingLabChart’sCyclicMeasurementsandSpectrumView.
Isolated perfused heartsWorking heart (Radnoti)MeasurehemodynamicparametersinsmallanimalheartswiththeRadnotiworkingheartsystem.Capped and water-jacketed to ensure constant perfusatetemperature,withportsforinsertionof cannulae and commonly-used pacing and ECG electrodes.Withadditionalinstrumentsyoucanmeasureatrialvolumeandcardiacoutput,left-ventricularpressure,pH,temperature,surface ECGandmore.
Isolated tissueTraditional organ baths (Radnoti) (left)Radnotimodularorganbathsystemsalloweasysubstitutionofparts,enablinganextensivechoiceoftissuetypesandchambersizes(5to300mL). Thewater-jacketedglasswareandtubingwithheatingcoilsintheorgan/tissuebathsensureconstanttemperaturemaintenancethroughoutthesystemforaccuratestudyofmusclecontraction,doseresponsesandmore(LabChartModulessupplied).
Langendorff heart (Radnoti and PanLab) (right)Monitorcardiacfunctionincludingleftventriculardevelopedpressure,HRandmore.Easilyswitchbetweenconstant-pressureandconstant-flowmodeswiththeconvenientpumpcontroller(includedwithsystem).
Isolated tissueAll-in-one compact organ baths (PanLab)Systemsavailablein4,8and16chambersidealforstriated,smoothandcardiacmusclestudies.Featuringelectrovalvesforautomatedfillingandemptyingoftissuechambers,aconstantsystemtemperatureisensuredbyenclosureoftissuevessels,reservoircoilsandtubinginasingletemperature-controlledwaterchamber.Systemsareprovidedwithisometrictransducers,howeverisotonictransducersandstimulatingelectrodesarealsoavailable.
Research applications
Isotonic force transducers
MyographsIdeal for in vitro studiesofmusclefunction,thesesystemsfeatureDMTWireMyographs.Investigatesmalltubulartissuesassmallas60μmindiameter,orlargermusclestrippreparations.TheyareSuppliedwiththeDMTNormalizationModuleforspeedyexperimentalset-up,andtheDoseResponseModuleforpharmacologicalassessmentofmusclecontraction,enzymeactivityandmore.Single,dualandfourchambersystemsareavailable,aswellas a confocal system for use with laser confocal scanningmicroscopy(LSCM).
WirelessdatarecordingElectromyography (EMG)Record true freedom of movement using systems withParallel-BarandMotionArtifactSuppressiontechnologiesfromDelsysInc.
SmallandlightweightEMGsensorshavebuilt-intriaxialaccelerometerswithaselectablerangeofg-forces.Upto16sensorscansimultaneouslytransmittherecordedsignalstoasinglereceiver.VariationsoftheEMGsensorssuchasminiEMGandSnap-Leadarealsoavailable.
Other wireless sensors include the EKG sensor for ECGmeasurementsandthe4contactforcesensitiveresistivesensor(FSR)forrelativeforceorpressuredistributionmeasurementsandtimingfrombody-contactsurfaces.
PowerfulfeaturesinLabChartprovideflexibledatadisplay with easy calculations including root mean square(RMS),powerspectraldensity(PSD),andintegration.
Neural recordingADInstrumentsandTriangleBioSystemsInc.(TBSI)provideawaytofasttrackbehavioral-electrophysiological research with industry-leading systemsforwirelessacquisitionofneuraldata.Systemsrecordfieldpotentialsorindividualneuralspikesfromsmallanimals(idealforrodents)usingimplantedmetalelectrodes.
NeuralsignalsaretransmittedbysmalllightweightheadstagesthatareavailablewithoptionssuchasLEDforvideotrackinginmazestudiesorexternalbatteriesforextendedrecordingtime.
ElectrophysiologyReady-to-use neurophysiology research systems,featuringWarnerInstruments’equipment,areidealforin vitro and in vivo applications.TheExtracellularRecordingSystemprovidesaversatile,lownoisedifferentialamplifier.TheIntracellularRecordingSystemprovidessimultaneouscurrent injection stimulation and recording using a singlemicroelectrode.
Systemsareavailablefortwo-electrode,whole-cellvoltageclampingoflargecellsandcellstructures.
Investigatetissuetransepithelialvoltage,shortcircuitcurrent,andmembraneresistanceusingepithelialSingleanddualchannelVoltageClampSystems.
Ussingchambersareavailableseparately,withinsertstosuityourresearchneedsthatcanbeeasilychangedbetweenexperiments.
Patchclampamplifiersofferarangeofresistive-feedbackheadstagesforcurrents±1,10and100nAinwholecellsorsingleionchannels.
MicroneurographyTheNeuroAmpExisalow-noise,high-gaindifferentialamplifierpurpose-builtforamplificationofextracellularsinglecell/tissuepotentialsandsinglenervefiberpotentials(split-nervepreparationorhumanmicroneurography).Electricallyisolatedforhuman connection it is supplied with a headstage andmicroelectrodeadapters.
Research applications
SpirometryandexercisephysiologyTheExercisePhysiologySystemincorporates avarietyofspecializedinstruments,transducersand accessories safe for human connection during exerciseandatrest.
HardwareincludesSpirometer,RespiratoryFlowHeads,GasAnalyzer,GasMixingChamber,ThermistorPod,temperaturesensorandsingle-channelbioamplifier.
MonitorandcalculatehumancardiorespiratoryandmetabolicparameterssuchasRR,volumeandflowrates,VCO2,VO2,VE,RER,intrathoracicpressureandlungsoundswiththeBP,HRV,MetabolicandECGAnalysismodulessupplied.
PsychophysiologyMeasureevokedresponsestovisualandauditorystimuli(VEP,ERPetc.)withacompletesystemthatincorporatesSuperLab®Software,StimTracker®andaccessoriessuchastheResponsePadandSmartVoiceKey(onecomputerisrequiredforstimuluspresentationandanotherfordataacquisition).
Skinconductance/temperature,respiratory,cardiac,andneurophysiologicalresponses,aswellasanalyzereactiontimeandreflexescanalsoberecordedusingoptionaltransducers.
INDUSTRY LEADERSPowerLabistheoriginal,highperformancedigitaldataacquisitionhardware,usedinalloftheTop100institutionsforlifescienceandcitedbymorethan20,000researchpapersinpeer-reviewedjournals.
ENVIRONMENTALLY FRIENDLYStrictmanufacturingprocesses,RoHScompliantparts,lead-freesoldering,anduseofrecycledandrecyclablematerialsensureswemeetourenvironmentalresponsibilities.
QUALITY AND RELIABILITYADInstrumentsproductsarecertifiedtomeetthestrictestinternationalsafetystandardsforhumanandanimaluse,includingtheCEmark.HardwareismanufacturedunderasystemcertifiedtocomplywithISO9001:2008.
DATA INTEGRITYPowerLabdataacquisitionsystemsaretestedandcalibratedtodeliverprecisiondataofthehighestquality.
PROVEN TRACK RECORDWith30yearsofdesignandmanufacturingexperience,wehaveinstalledmorethan45,000PowerLabdataacquisitionsystemsworldwide.
INTUITIVE USEOursoftwareismasteredquicklyandprovidescomprehensiverecording,displayandanalysisfeatures.
POWER AND FLEXIBILITYWhetheranimalorhuman,organ,tissueorcell,invivo,invitroorexvivo,oursystemsareadaptabletoavarietyoflifescienceapplications.
EXCELLENCE IN CUSTOMER TRAINING & SUPPORTOurin-housescientists,educators,programmersandbiomedicalengineersunderstandyourresearchneeds.Withrepresentativesinmorethan80countries,weprovideatrulyglobalsupportnetwork.
EXCLUSIVE DISTRIBUTIONWeofferanexclusiverangeofADInstrumentsandotherbrandproductsincludinggold-standardMillarcardiovascularproductsforresearch.
GLP & 21 CFR PART 11 COMPLIANCEOurGLPsoftwareprovidesadataacquisitionsolutionforGLPand21CFRPart11compliantenvironments.Theyprovideanon-editableaudittrailofallfileoperations,andacentralizeduserandsignatureauthorizationsystemthatverifiesuservalidity.
The ADInstruments advantage
PowerLab,LabChartandLabTutoraretrademarksofADInstrumentsPtyLtd.Allothertrademarksarethepropertyoftheirrespectiveowners.PowerLabsystemsandsignalconditionersmeettheEuropeanEMCdirective.ADInstrumentssignalconditionersforhumanuseareapprovedtotheIEC60601-1patientsafetystandardandmeetinternationalstandards.ISO9001:2008CertifiedQualityManagementSystem. GLP
21CFR Part11Compliance
adinstruments.com
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