Abbott presentation
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Transcript of Abbott presentation
Diagnostic and Diagnostic and Therapeutic BiomarkersTherapeutic Biomarkers
Wheeling High SchoolWheeling High School
Biology and Business Biology and Business StudentsStudents
Meet the ProblemMeet the Problem
Over 300 WHS Over 300 WHS Biology (honors and Biology (honors and general) and general) and Business studentsBusiness students
Students explore the Students explore the Meet the Problem Meet the Problem document.document.
Meet the ProblemMeet the Problem
Abbott Abbott Representatives Representatives Arlene Manelli and Arlene Manelli and Azza Wagdy Azza Wagdy
Explained the Explained the pharmaceutical pharmaceutical process process
Introduced the Introduced the Biomarker problemBiomarker problem
Question and Answer Question and Answer Session with the Session with the ScientistsScientists
Define the Problem: Define the Problem: As a research team As a research team
with fresh with fresh perspective, advise perspective, advise
Abbott on biomarker Abbott on biomarker research, both research, both diagnostic and diagnostic and
therapeutic to meet therapeutic to meet their goals.their goals.
Brainstorm a Class Know/Need/Do List
One to Three Research One to Three Research CyclesCycles
1.1. Find online articles and studies/conduct Find online articles and studies/conduct interviews that support a question on interviews that support a question on Know/Need/Do list.Know/Need/Do list.
2.2. Complete graphic organizer on the article/study.Complete graphic organizer on the article/study.
3.3. Report findings to group and combine findings Report findings to group and combine findings to create a summary document or presentation.to create a summary document or presentation.
4.4. Present findings to the class and field questions.Present findings to the class and field questions.
5.5. Revisit and Revise Problem and KND based on Revisit and Revise Problem and KND based on findings.findings.
Research and Research and TechnologyTechnology
District EmailDistrict EmailGoogle DocsGoogle Docs
Preselected studiesPreselected studies Preselected articlesPreselected articles Shared documentsShared documents Shared Shared
PresentationsPresentations
DatabasesDatabases iPadsiPads
Solutions for AbbottSolutions for Abbott
Biology Groups chose solutions, created and Biology Groups chose solutions, created and executed presentation plans.executed presentation plans.
Introduction to Business students viewed and Introduction to Business students viewed and summarized group solution documents from Biology summarized group solution documents from Biology students.students.
They interviewed Biology students about their They interviewed Biology students about their solutions and created a summary presentation for solutions and created a summary presentation for Abbott.Abbott.
On April 5, 2011, Biology student groups presented On April 5, 2011, Biology student groups presented and defended their findings to Abbott scientists. and defended their findings to Abbott scientists. Business students presented the overall findings to Business students presented the overall findings to Abbott.Abbott.
WHS Biology students were asked: “Is WHS Biology students were asked: “Is your solution Therapeutic or your solution Therapeutic or
Diagnostic?”Diagnostic?”
42% of students support Therapeutic solutions
58% support Diagnostic solutions
31% are both Diagnostic and Therapeutic
From 300 students reports covering all issues From 300 students reports covering all issues surrounding biomarkers, our business class surrounding biomarkers, our business class
summarized all the findings from the biology summarized all the findings from the biology students. This presentation is the summary of students. This presentation is the summary of
solutions that Abbott could use. solutions that Abbott could use.
Diagnostic SolutionsDiagnostic Solutions
A diagnostic biomarker is a test or molecule that can be measured and used as an indicator a disease or condition of a patients health.
The biology students believe that these diseases are good candidates for diagnostic biomarker research.
Lung Cancer Alzheimer's Autism Camurati-Engelmanns Cholera Lymphocytic Leukemia
Therapeutic SolutionsTherapeutic Solutions
A therapeutic biomarker is a molecule that is used within a biochemical pathway to adjust a process that is not working properly in order to restore proper functioning.
The biology students believe that these diseases are good candidates for therapeutic biomarker research.
Lymphocytic Leukemia
Cholera Celiac Disease HIV Autism Tay Sachs Malaria
PBL PBL Curricular Curricular OutcomesOutcomesIllinois Learning Illinois Learning StandardsStandards
NETS StandardsNETS Standards
Illinois Learning Illinois Learning Standards Standards
Practiced during PBLPracticed during PBL 11A: Know and apply the concepts 11A: Know and apply the concepts
principles and processes of principles and processes of scientific inquiry. scientific inquiry. (State H/I : 1-5)(State H/I : 1-5)
12A: Know and apply concepts that 12A: Know and apply concepts that explain how living things function, explain how living things function, adapt and change. adapt and change. (State H/I : 1, 2, (State H/I : 1, 2, 5)5)
13A: Know and apply accepted 13A: Know and apply accepted practices of science. practices of science. (State H : 2)(State H : 2)
13B: Apply concepts that describe 13B: Apply concepts that describe the interaction between science, the interaction between science, technology and society. technology and society. (State I : 1, (State I : 1, 2, 4)2, 4)
NETS Standards NETS Standards Practiced during PBLPracticed during PBL
1: Demonstrate creative thinking, 1: Demonstrate creative thinking, construct knowledge and develop construct knowledge and develop innovative products and processes innovative products and processes using technology (a, b, d)using technology (a, b, d)
2: Use digital media and 2: Use digital media and environments to communicate and environments to communicate and work collaboratively. (a, b, d)work collaboratively. (a, b, d)
3: Apply digital tools to gather, 3: Apply digital tools to gather, evaluate and use information (a-d)evaluate and use information (a-d)
4: Use critical thinking skills to plan 4: Use critical thinking skills to plan and conduct research, manage and conduct research, manage projects, solve problems, and make projects, solve problems, and make informed decision using appropriate informed decision using appropriate digital tools and resources. (a-d)digital tools and resources. (a-d)
5: Understand human, cultural and 5: Understand human, cultural and societal issues related to technology societal issues related to technology and practice legal and ethical and practice legal and ethical behavior. (b-d)behavior. (b-d)
Our Our ObservatioObservatio
nsns
After PresentationsAfter Presentations
Our Our ObservationsObservations
Googledoc and iPad Technology Googledoc and iPad Technology encouraged students to encouraged students to collaborate in real time.collaborate in real time.
Our Our ObservationsObservations
The interaction The interaction with Abbott with Abbott
scientists inspired scientists inspired students with students with
sense of purpose.sense of purpose.
Our Our ObservationsObservations
With each research With each research cycle, students became cycle, students became
more confident with more confident with presentation of presentation of
findings.findings.
Our Our ObservationsObservations
Students shared information and Students shared information and learned from the presentations of learned from the presentations of
others, enriching their understanding others, enriching their understanding and often redirecting the research of and often redirecting the research of
other groups.other groups.
Our Our ObservationsObservations
The opportunity for each group to The opportunity for each group to present their findings to outside present their findings to outside experts raised the level of expectation. experts raised the level of expectation. Students demonstrated a depth of Students demonstrated a depth of understanding.understanding.
Our Our ObservationsObservations
Career ExplorationsCareer Explorations
Research Research ScientistsScientists
PhysiciansPhysiciansMedical TechnicianMedical TechnicianMarketing AnalystsMarketing AnalystsAttorneyAttorneyManagersManagersEtc.Etc.
Future Future PlansPlans
New Problem: New Problem: Is the concern over radiation in Is the concern over radiation in foods a foods a real concern or is it media-real concern or is it media-driven? How can driven? How can we alleviate we alleviate public fear about food imported by public fear about food imported by
Japan?Japan?
Unit Content: Unit Content: Energy in Organisms and Energy in Organisms and EnvironmentEnvironment
DNA and MutationDNA and MutationCell Cycle and DevelopmentCell Cycle and DevelopmentEvolution of PopulationsEvolution of Populations
Business Partner: Business Partner: Mitsuwa MarketplaceMitsuwa Marketplace In June: In June: Present our findings to a Mitsuwa with a Present our findings to a Mitsuwa with a
plan for how plan for how Mitsuwa can alleviate fears.Mitsuwa can alleviate fears.