Mazor Robotics 1Mazor Surgical TechnologiesConfidential

A New Era In Robotic Spine Surgery

Ori Hadomi, CEO December 2010

Mazor Robotics

TASE - MZOR• 45 employees world wide• Offices: US, Germany & Israel• YTD financing: $49M; Cash balance : $17M

Mature Technology• Clinical effectiveness proven (>2,000 cases)• 7 CE & FDA cleared products

Clear & Validated Business Plan• Foothold in Germany & Russia• Ramping up sales activities in US• Executing Intuitive Surgical sales model

Bright Future• Transitioning into a “sales & marketing” company• Focused portfolio of products (“one stop shop” for spine surgery)• Expanding pipeline• Experienced sales and management team

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The Need For Robotics In Spine Surgery

Misplaced Pedicle screw Revision

Pedicle Screws Inserted Free-Hand Are Misplaced in 10% of Cases

Pedicle Screw Placement Accuracy: a Meta-AnalysisKosmopoulos V, Schizas C.; Spine 2007 Feb 1;32(3):E111-20

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SpineAssist Robotic Guided Surgery

4Operate

SpineAssist Workstation

CT-based SpineAssist Planning Software

SpineAssist Robot

Guiding Cannula

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Pre Operative Planning1. Plan

2. Mount

3. 3. 3D Synch

CT Fluoro

4. Operate

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Rigid Attachment for Accuracy and Precision

1Plan

4Operate

2Mount

33D Synch

CT Fluoro

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SpineAssist Procedure Flow

1Plan

4Operate

2Set-up

33DSynchCT Fluoro

A Clinically Validated System

• ~2,000 spine surgeries to date

• ~10,000 implants placed

Zero cases of nerve damageZero cases of nerve damage

• Used daily in leading centers in over 25 centers globally

• Clinically validated in complex and simple cases in Europe and the US

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Latest Multi Center Study Results

“SpineAssist offers enhanced performance

in spinal surgery when compared to free

hand surgeries, by increasing placement

accuracy and reducing neurological risks”

Devito et al., Clinical acceptance and accuracy assessment of spinal implants guided with SpineAssist surgical robot – retrospective study, Spine 2010;35(24) in press

• 840 cases in 14 hospitals • 49% of cases were percutaneous • 98% implant accuracy • 0 permanent neurological deficit

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Following The Path Of Success

• The model for the introduction of surgical Robotics to hospitals has been proven (Intuitive Surgical, Mako Surgical).

• Mazor is taking the blue print of success to the Spine market

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Revenue Model

4Operate

Spine Assist Surgical System$660K per OR

Implantable Devices$6-8K per procedure

Robot Disposable$1.2K per procedure

Service Agreement$66K per year

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In the PipelineProduct SpineAssist 2011 Crania Application Implantable

DevicesC-Insight

Intended USE Advanced platform + 3D Imaging

Precise positioning for Brain surgery

(DBS, Biopsy, Shunt Placement)

Robotic enabled MIS spine

stabilization procedures

Intra Operative 3D imaging

Regulatory StatusFDA

CEQ2/2011

Q2/2011Q1/2011Q1/2011

Emerald: Q1/2011GOLIF: CE cleared

ClearedCleared

Launch Plan June 2011 October 2011 Q4/11 Strategic partner – In

process

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Summary

• Mature technology with promising new products pipe line

• Proven business model and aggressive sale strategy

• Experienced management team

• Expanding sale to rest of Europe and the US

• Mazor Robotics Ticker in TASE: MZOR

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Thank You!

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