2018 GAEMS Providers & Educators Conference - …...Abstract Review Committee for the 23rd...
Transcript of 2018 GAEMS Providers & Educators Conference - …...Abstract Review Committee for the 23rd...
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Description of yourpresentation for eventprogram
2018 GAEMS Providers & Educators Conference - Call for Presentations
4009008355676426132
04-30-2018 07:33:57
Michael Frankel
MD
Professor & Director of Vascular Neurology; Chief of Neurology
Emory University School of Medicine; Grady Health System
80 Jesse Hill Jr. Dr. SEAtlantaGeorgia30303United States
(404) 616-0517
Michael Frankel CV .pdf
Michael Frankel Bio.docx
Michael Frankel.jpg
The Evolution in Systems of Stroke Care: Taking it to the Streets
The treatment of acute stroke has evolved over the past 30 years. Prior to 1996there was not an FDA-approved treatment for ischemic stroke. Although manyadvances have been made since that time, stroke remains the 5th leading causeof death in the US and a leading contributor to long-term disability. Dr. Frankelwill highlight the evolution of treatment options for acute ischemic stroke toinclude providing care at the earliest possible time - on the patient's doorstep.The learner will also view the project design of Georgia's first Mobile StrokeTreatment Unit and how it impacts Systems of Care.
Objectives of yourpresentation
Date Preferred (check all thatapply)
Time Preferred
Type of Session
Audio Visual EquipmentNeeded
Role Desired
Compensation Agreement
Define ischemic stroke and its impact on mortality & morbidity
Discuss various treatment options for acute stroke
Understand the current pre-hospital management of acute stroke
Identify the role of technology in the treatment of acute stroke
Discuss the international impact made by the mobile stroke treatment unit
Monday, Sept. 24, 2018
Afternoon
General Session (1 hr)
Laptop ComputerComputer ProjectionWireless Lapel Microphone
Regional Speaker
I agree to the above listing of compensation for my role desired, and will not holdGAEMS responsible for fees and expenses above those listed above.
Submission ID
Submission Date
Full Name
Certifications and Credentials
Job Title
Employer
Address
Work Phone Number
Cell Phone Number
Email Address
Attach curriculum vitae
Attach short biography
2018 GAEMS Providers & Educators Conference - Call for Presentations
4009019465671990814
04-30-2018 07:52:27
Carol Fleming
BSN RN CCRN
Outreach Director-Marcus Stroke Network
Grady Health System
80 Jesse Hill Jr. Drive SEAtlantaGeorgia30303United States
(404) 616-0517
(770) 557-4761
Carol Fleming CV.pdf
Carol Fleming Bio.docx
Attach publicity photo
Presentation Title
Description of yourpresentation for eventprogram
Objectives of yourpresentation
Why you want to speak at theGAEMS EducatorsConference
Grady_Fleming_Headshot.jpg
The Evolution in Systems of Stroke Care: Taking it to the Streets
The treatment of acute stroke has evolved over the past 30 years. Prior to 1996there was no FDA-approved treatment for ischemic stroke. Although manyadvances have been made since that time, stroke remains the 5th leading causeof death in the US and a leading contributor to long-term disability. Dr. Frankelwill highlight the evolution of treatment options for acute ischemic stroke toinclude providing care at the earliest possible time - on the patient's doorstep.The learner will also view the project design of Georgia's first Mobile StrokeTreatment Unit and how it impacts Systems of Care.
Define ischemic stroke and its impact on mortality & morbidity
Discuss various treatment options for acute stroke
Understand the current pre-hospital management of acute stroke
Identify the role of technology in the treatment of acute stroke
Discuss the international impact made by the mobile stroke treatment unit
I have a keen interest in pre-hospital care and how it impacts patient outcomes.Dr. Frankel and I will co-lead this discussion on Stroke, pre-hospitalmanagement and the future of innovative stroke care as it pertains to the pre-hospital provider.
Date Preferred (check all thatapply)
Time Preferred
Type of Session
Audio Visual EquipmentNeeded
Role Desired
Compensation Agreement
Monday, Sept. 24, 2018
Afternoon
General Session (1 hr)
Laptop ComputerComputer ProjectionWireless Lapel Microphone
Regional Speaker
I agree to the above listing of compensation for my role desired, and will not holdGAEMS responsible for fees and expenses above those listed above.
Carol Fleming is the Outreach Director for the new Marcus Stroke Network and has been project manager for the build-out of Georgia’s first Mobile Stroke Treatment Unit. Prior to transitioning to the director role, Carol served as outreach manager for Grady’s Marcus Stroke & Neuroscience Center. She has been the liaison between the MSNC, EMS and 70 partnering hospitals. Since becoming a registered nurse, Carol has gained 20+ years’ clinical experience in critical care, emergency and transport nursing. Her experience in the critical care setting and passion for the pre-hospital environment endorses a holistic understanding for systems of care.
Dr. Michael Frankel is professor of neurology at Emory University School of Medicine, and chief of neurology and director of the Marcus Stroke and Neuroscience Center at Grady Memorial Hospital.
Dr. Frankel has worked in the field of acute stroke research since 1992. He has served as Chief of Neurology for the Grady Health System for the past 20 years, devoting his academic, clinical and research interests to cerebrovascular disease. Under his leadership Grady Memorial Hospital has hosted major clinical trials, including the NIH sponsored t-PA Stroke Trial which led to the FDA approval of t-PA in acute stroke.
P
SKILLS
AFFILIATIONS
WORK H
07/2015 to
09/2005 to
CAROL FLEMING
3271 Woodcliff Way, Powder Springs, GA 30127
Cell: (770) 557-4761 - [email protected]
SUMMARY
Dedicated Nursing Professional with strong leadership and project management skills.
Expert in the detailed skills required to identify opportunities and streamline process
improvement. Proven track record in building professional relationships and growing
business in the competitive healthcare arena.
Project management Client assessment and analysis
Strategic planning Astute to client needs
Process improvement Strong emotional intelligence
Member, Air and Surface Transport Nurses
Member, Association American Association of Critical Care Nurses
2018 Chair, Georgia Stroke Professional Alliance
Outreach Manager
Grady Health System, Marcus Stroke & Neuroscience Center
Monitor all patient transfers and referrals to ensure effective and efficient
processes.
Plan and implement ongoing education to referring hospital partners and EMS
agencies.
Create and maintain regular reports for internal and external partners.
Maintain collaborative relationship medical &research staff, EMS and hospitals.
Extend Grady Health Systems footprint in competitive marketplace.
Project Manager for Mobile Stroke Unit Implementation. Director for Marcus Stroke
Network
Clinical Supervisor-Regional Clinical Compliance Manager
Air Methods Corporation
Direct clinical base education for 20 air medical transport locations and 160 clinicians.
Regulatory oversight of new employees
Business Development Partner for statewide education
Member of National Quality Council to improve patient outcomes
Supervision of base budget, scheduling and daily operations
Successfully grew program with new base openings and same base transports
ROFESSIONAL
ISTORY
Current
03/2017
01/1998 to 08/2006
07/1997 to 12/1997
06/1990 to 06/1997
EDUCATION
Registered Nurse
Atlanta Medical Center
Critical care RN managing patients with traumatic injuries, medical, surgical,
cardiovascular, neurological and neurosurgical conditions.
Resource/Charge nurse of a 37 bed ICU supervising 20+ RNs and support staff.
Preceptor and mentor to new clinicians.
Data collector for research based study drugs and equipment.
St Joseph's Hospital – Atlanta
Critical care RN in Medical CCU caring for patients with cardiac maladies.
Registered Nurse
Winchester Medical Center – Winchester, VA
Registered nurse employed in medical coronary care unit managing patients with
invasive monitoring, Intra-aortic balloon pumps, left ventricular assist devices as well as
maintenance of vasoactive medications.
Associates of Science: Nursing
Shenandoah University - Winchester
Bachelor of Science: Nursing
Georgia Southern University
MICHAEL FRANKEL, M.D.
CURRICULUM VITAE
OFFICE ADDRESS:
Box 036, 11C-030 Telephone: 404-616-4013
Dept. of Neurology Fax: 404-659-0849
Grady Memorial Hospital
80 Jesse Hill Jr. Drive, SE
Atlanta, GA 30303
E-mail ADDRESS: [email protected]
CITIZENSHIP: United States of America
CURRENT TITLES AND AFFILIATIONS:
Primary Academic Appointments:
2003 – present Professor of Neurology
Emory University School of Medicine
Clinical Appointments:
2010 – present Director of the Marcus Stroke & Neuroscience Center
Grady Health System
Atlanta, GA
2004 – present Director of Vascular Neurology
Emory University School of Medicine
1992 – present Chief of Neurology
Grady Health System
PREVIOUS ACADEMIC AND PROFESSIONAL APPOINTMENTS:
Academic Appointments:
1998 – 2003 Associate Professor of Neurology
Emory University School of Medicine
1992 - 1998 Assistant Professor of Neurology
Emory University School of Medicine
Training Director Appointments:
2003 – 2012 Fellowship Director
Vascular Neurology
Emory University School of Medicine
LICENSURE/BOARDS:
Georgia Board of Medical Examiners
License number: 034832
Diplomate of the National Board of Medical Examiners
SPECIALTY BOARD CERTIFICATIONS:
1. Neurology, 1993
American Board of Psychiatry & Neurology
2. Clinical Neurophysiology, 1994
American Board of Psychiatry & Neurology
3. Vascular Neurology, 2008
American Board of Psychiatry & Neurology
EDUCATION:
Aug 79-Jul 81 University of Louisville
Aug 81-May 83 B.S. in Biochemistry, Tulane University
MEDICAL EDUCATION:
Aug 83-May 87 M.D., University of Louisville School of Medicine (5/17/1987)
POSTGRADUATE TRAINING:
INTERNSHIP:
Jul 87-Jun 88 Internal Medicine - Emory University School of Medicine
Supervisor: Juha Kokko, M.D., Chairman of Internal Medicine
RESIDENCY:
Jul 88-Jun 91 Neurology - Emory University School of Medicine
Jul 90-Jun 91 Chief Resident in Neurology - Emory University
Supervisor: Mahlon DeLong, M.D., Chairman of Neurology
FELLOWSHIP:
Jul 91-Jun 92 Clinical Neurophysiology (Electroencephalography &
Electromyography) Emory University School of Medicine
Supervisor: Linton Hopkins, M.D., Professor of Neurology
COMMITTEE MEMBERSHIPS:
NATIONAL:
Randomized Trial of Tirilazad in Acute Stroke, NIH Safety & Monitoring Committee,
1996
Steering Committee for the NINDS t-PA Stroke Trial Group (1992 - present).
CV: Michael R. Frankel, M.D.
Page - 3
Publications Committee for the NINDS t-PA Stroke Trial Group, 1992 – present.
Abstract Review Committee for the 22nd International Conference on Stroke, 1997.
Abstract Review Committee for the 23rd International Conference on Stroke, 1998.
Abstract Review Committee for the American Academy of Neurology Meeting -
Cerebrovascular Disease Section, 1998.
Steering Committee for Warfarin vs Aspirin Symptomatic Intracranial Disease Study
(WASID), 1999 to present.
Steering Committee for CDC sponsored, “Paul Coverdell National Acute Stroke
Registry”, Sept 2001 – present.
National Steering Committee for the American Heart/American Stroke Association’s
“Get With The Guidelines” program, June 2004 – present.
National Board of Directors, American Heart Association, 2005-2007.
American Stroke Association National Advisory Committee, 2005-2006.
Joint Commission’s “Technical Advisory Panel” on Comprehensive Stroke Center
Certification, 2013-present
REGIONAL/STATE:
Chairman - Stroke Advisory Committee and Task Force for the American Heart
Association, Georgia Affiliate, July 1997 - 1998.
Member, Stroke Task Force Committee for the Southeastern Affiliate of The American
Heart Association, 1999.
President, Georgia Strike Out Stroke Committee, 1999 to present.
Co-Chairman - The Greater Atlanta Stroke Coalition, 1998-1999.
Co-Chairman - The Metro Atlanta Stroke Task Force, American Heart Association Heart
Association 1999 - 2000.
Member, Minority Involvement Committee, American Heart Association, 1997 - 1999.
Member, Community Advising Committee for the NIH Sponsored Study called
“WASID”.
CV: Michael R. Frankel, M.D.
Page - 4
Member, Georgia Research Consortium Stroke Group, 1999.
Co-Chairman, Operation Stroke for Atlanta, American Stroke Association (AHA), 1999 -
2002.
Co-Chairman, Hospital/EMS subcommittee, Operation Stroke for Atlanta, American
Stroke Association, 1999 - present.
Member, Steering Committee, Operation Stroke for Atlanta, American Stroke
Association, 1999 – present.
Co-Chairman, “Check your pulse America”, National Stroke Association sponsored
campaign to increase detection of atrial fibrillation, July/2000, Atlanta, GA.
Member, LifeLink of Georgia Advisory Board, December, 2001 to 2008.
Member, Tri-State (GA, NC, & SC) Stroke Network, 2001 to present.
Vice President, American Heart Association, Southeast Affiliate (5 states). 2002 – 2003.
“Stroke Champion” for Atlanta for the American Stroke Association’s Beta Pilot called,
“Get With The Guidelines”, 2002 – present.
Member, R. Bruce Logue Advisory Board, 2002-present. The Board selects an award
recipient each year – a physician who has distinguished themself as a healer, scientist,
teacher, leader and humanitarian.
President-elect, American Heart Association, Southeast Affiliate (5 states). 2003 – 2004.
President, American Heart Association, Southeast Affiliate. 2004 – 2005.
Co-Chair, Cultural Initiatives Committee, AHA Southeast Affiliate, 2004 – 2005.
Co-Chair, Stroke Systems of Care Task Force, AHA Greater Southeast Affiliate, 2009-
2011
Member, Remote Stroke Treatment Center Committee for Georgia, 2014-present
Co-Chair, Mission Lifeline for Stroke, AHA Greater Southeast Affiliate, 2015-present
INSTITUTIONAL:
Medical Executive Committee for the Grady Health System, 1992 – present.
Emory Neurology Residency Committee, 1992 – present.
CV: Michael R. Frankel, M.D.
Page - 5
Emory Neurology Medical Student Education Committee, 1996 – present.
Grady Medical Staff By-Laws Committee, 1996 – present.
The Emory Clinical Pathway for Stroke Committee, 1993 – 1995.
Emory University Faculty Senate, 1995.
Steering Committee member for the Warfarin Aspirin Symptomatic Intracranial Disease
(WASID) Trial, 1997 - present.
Group Leader for the Grady Health System Verbal Orders Committee, 1998 - present.
Grady/Emory Relations Committee, 1999.
Member, Grady Health System IRB, 1999 to present.
Member, Grady Research Oversight Committee, 1998 - present.
Group Leader, Grady Stroke Clinical Pathway Committee, 1999 - present.
Group Leader for the Grady Medical Records Delinquency Task Force, 2001.
Chairman, Grady Health System Research Oversight Committee, June 2001 – present.
Member, Executive Committee, Department of Neurology, Emory University, 2002 –
2003.
Member, Emory Medical Care Foundation Research Committee, July 2002 – present.
Member, General Advisory Committee, General Clinical Research Center (GCRC) at
Grady, 2003.
Member, Program Directors’ Committee, Department of Neurology, Emory University,
2004 – present.
Member, Emory University School of Medicine’s Continuing Medical Education
Advisory Committee, 2005 – present.
Chair, Emory University Hospital Multidisciplinary Stroke Committee, 2005 - .
Chair, Emory Healthcare Comprehensive Stroke Center Planning Committee, 2005 - .
Co-Chair, Grady Health System Neuroscience Service Line Committee, 2006 - .
CV: Michael R. Frankel, M.D.
Page - 6
Member, Emory University Hospital – Midtown, Multidisciplinary Stroke Committee,
2011-
Advisory Committee to Emory’s Executive Associate Dean for Grady Affairs
CONSULTANTSHIPS:
Data and Safety Monitoring Committee for the Upjohn sponsored study of Tirilizad in
acute ischemic stroke, 1996.
MANUSCRIPT REVIEWER:
ADHOC reviewer: Neurology, 1996 & 1997; Stroke, 1999 and 2000; The Neurologist,
2000, 2002, 2006, 2007; Journal of Hospital Medicine, 2006
HONORS and AWARDS:
1996 Neurology Faculty Teaching Award, presented by neurology residents.
Best Neurology Faculty Teaching Award – 1999, presented by the Emory University
Medical School graduating class of 1999.
Special Recognition Award for Excellence in Teaching - 1999, presented by neurology
residents.
2002 Neurology Faculty Teaching Award, presented by neurology residents.
2007 Neurology Faculty Teaching Award, presented by neurology residents
2008 Elected to Alpha Omega Alpha (AOA) by Emory Medical Students
SOCIETY MEMBERSHIPS:
American Academy of Neurology
American Neurological Association
American Stroke Association/American Heart Association – Stroke Council
ORGANIZATION OF NATIONAL OR INTERNATIONAL CONFERENCES:
Steering Committee, National Institute of Neurological Disorders and Stroke Symposium:
The Rapid Identification and Treatment of Acute Stroke, 1996.
Co-Chair, Emergency Department Subcommittee for the NINDS Symposium: The Rapid
CV: Michael R. Frankel, M.D.
Page - 7
Identification and Treatment of Acute Stroke, 1996.
Co-Chair, Hospital Care Subcommittee for the NINDS Symposium: The Rapid
Identification and Treatment of Acute Stroke, 1996.
International Advisory Board. The Xth International Symposium on Thrombolysis and
Acute Stroke Therapy in Budapest, Hungary - September 21-23, 2008.
Organizing faculty for the 4th International Conference on Intracranial Atherosclerosis,
Sept/2011, in Valladolid, Spain.
ORGANIZATION OF REGIONAL/STATE CONFERENCES:
Co-Chair, Greater Atlanta Stroke Coalition, 5/98.
Co-Chair, “Stroke Summit 1999", Metro Atlanta Stroke Task Force, American Heart
Association, 5/99.
Co-Chair, “Stroke Summit 2000", Operation Stroke for Atlanta, American Stroke
Association, 5/26/00.
Co-Chair, “Educating Metro-Atlanta Hospitals about Acute Stroke Treatment”, American
Stroke Association, Sheraton Hotel, Atlanta, GA, 1/16/01.
RESEARCH FOCUS:
Research and academic focus has been in the clinical areas of cerebrovascular disease
including clinical trials, acute treatment of stroke, stroke prevention, stroke epidemiology,
stroke recovery, racial differences in stroke, cerebrovascular imaging, outcomes, quality
improvement of stroke, collaborative models of stroke care, biomarkers in stroke and
traumatic brain injury, and clinical trials in traumatic brain injury.
GRANT SUPPORT:
ACTIVE
Federally funded:
Principal Investigator, “NINDS Stroke Trials Network - Regional Coordinating Stroke
Centers (U10)”. Title: “Georgia StrokeNet”. Funded by NIH/NINDS. 1U10NS086607-
01. 9/25/2013-7/31/2018. Award amount: $1,950,000
Principal Investigator, “Biomarkers of Ischemic Outcomes in Symptomatic Intracranial
Stenosis (BIOSIS)”. Funded by NIH/NINDS. 1R01NS064162-01. 7/1/2010 –
CV: Michael R. Frankel, M.D.
Page - 8
6/30/2014. Award amount: $1,474,835. “No-cost” extension phase
Principal Investigator, Biomarkers of Injury and Outcomes in ProTECT III” (BIO-
ProTECT). Funded by NIH/NINDS. 1R01NS071867. 5/1/2010 – 4/30/2015. Award
amount: $2,614,136
Principal Investigatory (for Emory University), “Ethnicity and Race in Intracerebral
Hemorrhage (ERICH)”. Funded by NIH/NINDS 1U01NS069763-01. Subcontract with
University of Cincinnati. 8/1/2011-7/31/2015.
Principal Investigator (for Emory University), “Georgia Coverdell Stroke Registry”.
Funded by CDC/Georgia Dept. of Human Resources. 5/1/2005 – 6/30/2015.
Co-Principal Investigator at Emory University (w/David Wright, Co-PI),
2U10NS059032-06, Neurological Emergencies Treatment Trials (NETT) Network,
sponsored by NIH/NINDS. 2012-2017.
Co-Principal Investigator at Emory University (Stewart Factor, PI). “Network of
Excellence in Neuroscience (NeuroNEXT)”. Funded by NIH/NINDS 5U10NS077366-03 09/01/13 – 06/30/14 0.60 calendar mon
Award amount: $242,052
Site Principal Investigator (Grady Hospital) for the ProTECT III trial (progesterone in
acute TBI), (David Wright, PI), sponsored by NIH/NINDS. 2010-2015.
PREVIOUS SUPPORT:
Federally funded:
Principal Investigator at Emory University for, “Secondary Prevention of Small
Subcortical Strokes (SPS3) study”. Funded by NIH/NINDS, subcontract with UT San
Antonio. 2/1/04 – 2012.
Principal Investigator, “Validation of Stroke Care Quality Indicators for the Paul
Coverdell National Acute Stroke Care Registry”. Funded by CDC/AAMC Cooperative
Agreement, 10/1/05 – 9/30/09.
Principal Investigator, “Track and Improve Outcomes After Stroke”. Funded by
CDC/AAMC Cooperative Agreement, 10/1/04 – 9/30/07.
Principal Investigator at Emory University for, “Ischemic Stroke Genetics Study (ISGS)”.
Funded by NINDS, subcontract with Mayo Clinic. 6/01/05 – 5/31/07.
Principal Investigator at Emory University for, “The Paul Coverdell National Acute
Stroke Registry – Georgia’s Acute Stroke Registry”. 9/1/01-1/31/04. Funded by Centers
for Disease Control and Prevention (CDC).
CV: Michael R. Frankel, M.D.
Page - 9
Co-PI for Progesterone treatment of blunt traumatic brain injury (ProTECT), sponsored
by NIH, 2000 – 2005.
Principal Investigator at Emory University, “Interventional Management of Stroke”,
funded by NINDS, subcontract with University of Cincinnati, 2000 – 2004.
Co-Investigator for Warfarin vs Aspirin in Symptomatic Intracranial Disease (WASID)
study, NINDS sponsored, 1999 – 2005.
Principal Investigator at Emory University, African American Antiplatelet Stroke
Prevention Study sponsored by NIH, 1997 - 2000. Subcontract with Rush-Presbyterian
University.
Subinvestigator, Siblings With Ischemic Stroke Study (SWISS), NIH sponsored,
subcontract with Mayo Clinic, Barney Stern – PI at Emory. 2001 – 2004.
Principal Investigator at Emory University for the NIH/NINDS Sponsored t-PA Stroke
Trial, NO1, 1992 - 1995.
Industry Sponsored:
Co-Investigator, “Trevo Trial”, Phase III study of stent retrieval device in acute ischemic
stroke, Stryker, Inc 2010-2012. (PI: Nogueira).
Principal Investigator at Emory, “SPARCL”, Phase III study of Atorvastatin after TIA or
Ischemic Stroke, Sponsored by Pfizer, 2000 – 2006.
Principal Investigator at Emory University, Citicoline for Acute Ischemic Stroke,
sponsored by Interneuron Pharmaceuticals, 1998.
Principal Investigator at Emory University, Clomethiazole Acute Stroke Study in
Ischemic Stroke (CLASS-I), Clomethiazole Acute Stroke Study - t-PA (CLASS-T), and
Clomethiazole Acute Stroke Study - Hemorrhage (CLASS-H), sponsored by Astra
Pharmaceuticals, 1998.
Principal Investigator at Emory University in the Study of Clopidogrel vs Aspirin in
patients at risk for ischemic events. Sponsored by Sanofi-Winthrop Pharmaceuticals,
1992 - 1996.
Principal Investigator at Emory University for the Emergency Management of Stroke
Bridging Trial. Sponsored by Genentech., 1996.
Principal Investigator at Emory University Cerestat for Acute Ischemic Stroke, sponsored
by Boehringer Ingelheim, 1996 - 1997.
CV: Michael R. Frankel, M.D.
Page - 10
Co-Investigator, Activated Protein C Resistance and Risk of Stroke. Joint Project with
the Center for Disease Control (CDC), 1997 -1999.
Principal Investigator at Emory University, ProUrokinase for Acute Middle Cerebral
Artery Territory Infarction (PROACT) sponsored by Abbott Pharmaceuticals, 1996 -
1999.
Principal Investigator at Emory University, Hu23F2G Anti-adhesion to Limit cytoToxic
injury in Stroke (HALT Study) for Stroke, sponsored by ICOS Corporation, 1997 – 1998.
Principal Investigator at Emory University, Fiblast Stroke Study, sponsored by Wyeth-
Ayerst, 1998.
Foundation Sponsored:
Principal Investigator at Emory University, Cord blood infusion for patients with acute
ischemic stroke. Sponsored by the Marcus Foundation (Joanne Kurtzberg, PI). 2015-
2016.
Other:
Sickle Cell Stroke Prevention Study (The Stop Study), Transcranial Doppler technical
support supervision for Emory, NIH sponsored, first phase, 1995-97.
CLINICAL SERVICE CONTRIBUTIONS:
Established the Marcus Stroke & Neuroscience Center at Grady which opened in
May/2010
FORMAL TEACHING and INVITED LECTURES: (available on request)
INVITATIONS TO NATIONAL OR INTERNATIONAL CONFERENCES
INVITED ORAL PRESENTATIONS:
“Predicting poor prognosis after stroke: Results of a placebo analysis from the NINDS rt-
PA Stroke Study”, oral presentation at the American Academy of Neurology Annual Mtg,
5/2/00.
“Preliminary results from 4 state pilot prototypes of the Paul Coverdell National Acute
Stroke Registry”, oral presentation at the International Stroke Conference, Phoenix, AZ,
2/15/03.
“Preliminary results of the Biomarkers of Ischemic Outcomes in Symptomatic
CV: Michael R. Frankel, M.D.
Page - 11
Intracranial Stenosis (BIOSIS) study”. International Conference on Intracranial Arterial
Disease (ICAD). Houston, TX. Fall/2013.
“Coverdell Stroke Registry”, oral presentation for the Florida-Puerto Rico Stroke
Registry (NINDS sponsored), Sept/2014.
INVITED ATTENDANCE
NINDS Symposium on The Rapid Identification and Treatment of Acute Ischemic
Stroke, 12/96.
American Academy of Neurology Annual Meeting, Minneapolis, April, 1998. Co-Chair
of the Clinical Cerebrovascular Diseases session. (Unable to attend)
American Heart Association Southeastern Affiliate Conference on Stroke, Atlanta, GA,
8/14/98.
American Academy of Neurology Annual Meeting, Toronto, April 1999. Co-Chair of
“Stroke Therapy” oral abstract presentation session.
American Academy of Neurology Annual Meeting, San Diego, May 2000. Co-Chair of
“Cerebral Hemorrhage” oral abstract presentation session.
BIBLIOGRAPHY:
PUBLISHED ARTICLES in REFEREED JOURNALS:
1. Krendel DA, Ditter SM, Frankel MR, Ross WK. Biopsy-proven cerebral vasculitis
associated with cocaine abuse. Neurology 1990;40:1092-1094.
2. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group.
Tissue Plasminogen Activator for Acute Ischemic Stroke, N Engl J Med 1995;333:1581-
7.
3. Qureshi A, Safdar K, Weil J, Barch C, Bliwise D, Colohan A, Mackay B, Frankel MR.
Predictors of Early Deterioration and Mortality in African-Americans after Intracerebral
Hemorrhage. Stroke, Vol 26, No 10, October 1995, 1764-1767.
4. Qureshi A, Frankel MR. Loss of Autoregulation in Patients with Intracerebral
Hemorrhage, J. Stroke Cerebrovasc Dis, Vol 5, No.3, 1995 163-165.
5. Qureshi A, Frankel MR, Ottenlips J, Stern B. Cerebral Hemodynamics in Eclampsia and
Pre-eclampsia. Arch Neurol 1996; 53:1226-1231.
6. Lyden P, Grotta J, Levine S, Marler J, Frankel MR, Brott T. Intravenous Thrombolysis
CV: Michael R. Frankel, M.D.
Page - 12
for Acute Stroke. Neurology 1997; 49:14-29.
7. Qureshi A, Janssen R, Karon J, Weissman JP, Akbar S, Safdar K, Frankel MR. Human
Immunodeficiency Virus Infection and Stroke in Young Patients. Arch Neurol.
1997;54:1150-53.
8. Qureshi A, Muhammed A, Janssen R, Frankel MR. Intracerebral Hemorrhage in Blacks:
Risk Factors Subtypes and Outcome. Stroke 1997; 28:961-64.
9. The NINDS rt-PA Stroke Study Group. Intracerebral hemorrhage after intravenous t-PA
therapy for ischemic stroke. Stroke 1997;28:2109-2118.
10. The NINDS rt-PA Stroke Study Group. Generalized efficacy of tPA for acute stroke:
Subgroup analysis of the NINDS t-PA Stroke Trial. Stroke 1997; 28:2119-2125.
11. The NINDS rt-PA Stroke Study Group. A systems approach to immedicate evaluation
and management of hyperacute stroke. Experience at 8 centers and implications for
community practice and patient care. Stroke. 1997;28:1530-1540.
12. Qureshi A, Akbar MS, Czander E, Safdar K, Jannsen RS, Frankel MR. Crack Cocaine
Use and Stroke in Young Patients. Neurology 1997; 48:341-45.
13. Fagan SC, Morgenstern LB, Petita A, Ward R, Tilley B, Marler J, Broderick J, Levine
SR, Kwiatkowski T, Frankel MR, Walker MD and the NINDS rt-PA Stroke Trial
Investigators. The cost effectiveness of t-PA for acute ischemic stroke. Neurology
1998;883-890.
14. Qureshi A, Safdar K, Patel M, Jannen RS, Frankel MR. Stroke in Young Black Patients,
Risk Factors, Subtypes and Prognosis, Stroke, Vol 26, No. 11, November 1995, 1995-
1998.
15. Brott T, Kothari R, Fagan S, Frankel MR, et al. Hypertension and its Treatment in the
NINDS t-PA Stroke Study. Stroke, 1998; 29:1504-1509.
16. Qureshi A, Isa A, Cinnamon J, Fountain J, Ottenlips JR, Braimah J, Frankel MR.
Magnetic resonance angiography in patients with brain infarction. Journal of
Neuroimaging, 1998;8:65-70.
17. Lewandowski CA, Frankel MR, Tomsick TA, et al. Combined intravenous and intra-
arterial rt-PA versus intra-arterial therapy of acute ischemic stroke: The Emergency
Management of Stroke (EMS) Bridging Trial. Stroke. 1999;30:2598-2605.
18. Qureshi A, Frankel MR, et al. Rate of 24-hour Blood Pressure Decline and Mortality
after spontaneous intracerebral hemorrhage: A retrospective analysis with a random
effects regression model. Intracerebral Hemorrhage and Mortality. Crit Care Med, 1999;
CV: Michael R. Frankel, M.D.
Page - 13
Vol 27, No 3, 480-485.
19. Kwiatkowski TG, Libman R, Frankel MR, Tilley B, Morgenstern LB, Lu M, Broderick
J, Marler J, Brott T, and the NINDS t-PA Stroke Study Group. The NINDS rt-PA stroke
study: The effects of t-PA for acute ischemic stroke at one year. N Engl J Med,
1999;340:1781-7.
20. Grotta JC, Chiu D, Liu M, Patel S, Levine SR, Tilley BC, Brott TG, Haley EC, Lyden
PD, Kothari R, Frankel MR, et al. Agreement and Variability in the Interpretation of
Early CT Changes in Stroke Patients Qualifying for Intravenous rtPA Therapy. Stroke,
1999; 30:1528-1533.
21. Qureshi A, Mohammad Y, Yahia AM, Luft AR, Sharma M, Tamargo RJ, Frankel MR.
Ischemic events associated with unruptured intracranial aneurysms: multicenter clinical
study and review of the literature. Neurosurgery 2000; 46(2):282-9.
22. Frankel MR, Morgenstern LB, Kwiatkowski T, Lu M, Tilley BC, Broderick JP, Libman
R, Levine SR, Brott T. Predicting prognosis after stroke, A placebo group analysis from
the National Institute of Neurological Disorders and Stroke rt-PA Stroke Trial. Neurology
2000;55:952-959.
23. Broderick JP, Lu M, Kothari R, Levine SR, Lyden PD, Haley EC, Brott TG, Grotta J,
Tilley BC, Marler JR, Frankel M, and the NINDS rtPA Stroke Study Group. Finding the
Most Powerful Measures of the Effectiveness of Tissue Plasminogen Activator in the
NINDS tPA Stroke Trial. Stroke 2000;31:2335-2341.
24. Marler JR, Tilley BC, Lu M, Brott TG, Lyden PC, Grotta JC, Broderick JP, Levine SR,
Frankel MR, Horowitz SH, Haley EC, Lewandowski CA, Kwiatkowski TP for the
NINDS rt-PA Stroke Study Group. Early stroke treatment associated with better
outcome. The NINDS rt-PA Stroke Study. Neurology 2000;55:1649-1655.
25. The NINDS tPA Stroke Study Group. Effect of intravenous tPA on ischemic stroke
lesion size measured by CT: Results from the NINDS tPA Stroke Trial. Stroke 2000; 31:
2912-2919
26. Grotta JC, Welch KMA, Fagan SC, Lu M, Frankel MR, Brott T, Levine SR, and Lyden
PD for the NINDS rt-PA Stroke Study Group. Clinical Deterioration Following
Improvement in the NINDS rt-PA Stroke Trial. Stroke 2001; 32: 661-668.
27. Rowe AK, Frankel MR, Sanders KA. Stroke awareness among Georgia adults:
epidemiology and considerations regarding measurement. Southern Medical Journal
2001:94:613-618.
28. Lyden P, Lu M, Kwiatkowski T, Frankel M, Levine S Broderick J, Brott T, and the
NINDS rt-PA Stroke Study Group. Thrombolysis in patients with transient neurologic
CV: Michael R. Frankel, M.D.
Page - 14
deficits. Neurology, 2001; 57:2125-2128.
29. Patel SC, Levine SR, Tilley BC, Grotta JC, Lu M, Frankel M, et al. for the National
Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Lack of
Clinical Significance of Early Ischemic Changes on Computed Tomography in Acute
Stroke. JAMA 2001; 286(22).
30. Qureshi AI, Mohammad Y, Suri MFK, Braimah J, Janardhan V, Guterman LR, Hopkins
LN, Frankel MR. Cocaine use and hypertension are major risk factors for intracerebral
hemorrhage in young African Americans. Ethnicity & Disease 2001;11:311-319.
31. Bruno A, Levine SR, Frankel MR, et al. Admission Glucose Level and Outcomes in the
NINDS rt-PA Stroke Trial. Neurology 2002;59:669-674.
32. Meschia JF, Brott TG, Brown RG, Crook R, Frankel MR, Hardy J, Merino J, Rich SS,
Silliman S, Worrall B. The Ischemic Stroke Genetics Study (ISGS) Protocol. BMC
(BioMed Central) Neurology 2003, 3:4(8 July 2003).
33. IMS Study Investigators. Combined Intravenous and Intra-Arterial Recanalization for
Acute Ischemic Stroke: The Interventional Management of Stroke Study. Stroke. 2004
Apr;35(4):904-11.
34. Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick J, Brott T, Frankel
M, Grotta JC, Haley EC Jr, Kwiatkowski T, Levine SR, Lewandowski C, Lu M, Lyden P,
Marler JR, Patel S, Tilley BC, Albers G, Bluhmki E, Wilhelm M, Hamilton S.
Association of outcome with early stroke treatment: pooled analysis of ATLANTIS,
ECASS, and NINDS rt-PA stroke trials. Lancet 2004 Mar 6;363(9411):768-74.
35. Azran MS, Waljee A, Biousse V, Frankel M, Newman NJ. Episodic third nerve palsy
with cryptococcal meningitis. Neurology. 2005 Feb 22;64(4):759-60.
36. Turan TN, Hertzberg V, Weiss P, McClellan W, Presley R, Krompf K, Karp H, and
Frankel MR. Clinical Characteristics of Patients With Early Hospital Arrival After
Stroke Symptom Onset. Journal of Stroke and Cerebrovascular Diseases, Vol. 14, No. 6
(November-December), 2005: pp 272-277.
37. Chimowitz MC, Lynn MS, Howlett-Smith H, Stern BJ, Hertzberg VS, Frankel MR, et
al. Comparison of Warfarin and Aspirin for Symptomatic Intracranial Arterial Stenosis.
N Engl J Med 2005; 352:1305-16.
38. Libman, R.B., Kwiatkowski T, Lyden P, Grotta J, Tilley BC, Fagan, S, Levine, S,
Broderick, J, Lin, Y, Lewandowski C, and Frankel, M. Asymptomatic hemorrhagic
transformation of cerebral infarction does not worsen long -- term outcome. Journal of
Stroke and Cerebrovascular Diseases March - April, 2, 2005, 50-54.
CV: Michael R. Frankel, M.D.
Page - 15
39. Reeves MJ, Arora S, Broderick JP, Frankel M, Heinrich JP, Hickenbottom S, Karp H,
LaBresh KA, Malarcher A, Moomaw CJ, Schwamm L, Weiss P; Paul Coverdell
Prototype Registries Writing Group. Acute stroke care in the US: results from 4 pilot
prototypes of the Paul Coverdell National Acute Stroke Registry. Stroke. 2005
Jun;36(6):1232-40.
40. The NINDS tPA Stroke Study Group. Recombinant t-PA for minor strokes Ann Emerg
Med 2005;46(3):243-52.
41. Hertzberg V, Weiss P, Stern BJ, and Frankel MR. Family history associated with
improved functional outcome following ischemic stroke. Neuroepidemiology.
2006;27(2):74-80
42. Kasner SE, Chimowitz MI, Lynn MJ, Howlett-Smith H, Stern BJ, Hertzberg VS, Frankel
MR, Levine SR, Chaturvedi S, Benesch CG, Sila CA, Jovin TG, Romano JG, Cloft HJ;
Warfarin Aspirin Symptomatic Intracranial Disease Trial Investigators. Predictors of
stroke in the territory of a symptomatic intracranial arterial stenosis. Circulation
2006;113:555-563.
43. Wright DW, Kellermann AL, Hertzberg VS, Clark PL, Frankel MR, Goldstein FC,
Salomone JP, Dent LL, Harris OA, Ander DS, Lowery DW, Patel MM, Denson DD,
Gordon AB, Wald MM, Gupta S, Hoffman SW, and Stein DG. ProTECT: A
Randomized Clinical Trial of Progesterone for Acute Traumatic Brain Injury.
Ann Emerg Med. 2006 Sep 28.
44. Kasner SE, Lynn MJ, Chimowitz MI, Frankel MR, Howlett-Smith H, Hertzberg VS,
Chaturvedi S, Levine SR, Stern BJ, Benesch CG, Jovin TG, Sila CA, Romano JG, for the
Warfarin Aspirin Symptomatic Intracranial Disease (WASID) Trial Investigators.
Warfarin vs aspirin for symptomatic intracranial stenosis: Subgroup analyses from
WASID. Neurology 2006;67 1275-1278
45. Meschia JF, Case LD, Worrall BB, Brown RD Jr, Brott TG, Frankel M, Silliman S, Rich
SS; Ischemic Stroke Genetics Study Group. Family history of stroke and severity of
neurologic deficit after stroke. Neurology. 2006 Oct 24;67(8):1396-402.
46. Schwamm L, Reeves MJ, Frankel M. Designing a sustainable national registry for stroke
quality improvement. Am J Prev Med 2006 Dec;31(6 Suppl 2):S251-7.
47. Reeves MJ, Broderick JP, Frankel M, LaBresh KA, Schwamm L, Moomaw CJ, Weiss P,
Katzan I; Paul Coverdell Prototype Registries Writing Group, Arora S, Heinrich JP,
Hickenbottom S, Karp H, Malarcher A, Mensah G, Reeves MJ.The Paul Coverdell
National Acute Stroke Registry: initial results from four prototypes. Am J Prev Med 2006
Dec;31(6 Suppl 2):S202-9.
CV: Michael R. Frankel, M.D.
Page - 16
48. Matarín M, Brown WM, Scholz S, Simón-Sánchez J, Fung HC, Hernandez D, Gibbs JR,
De Vrieze FW, Crews C, Britton A, Langefeld CD, Brott TG, Brown RD, Worrall BB,
Frankel M, Silliman S, Case LD, Singleton A, Hardy JA, Rich SS, Meschia JF, A
genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data
release. Lancet Neurology 6:414-20 2007
49. Chaturvedi S, Turan TN, Lynn MJ, Kasner SE, Romano J, Cotsonis G, Frankel M,
Chimowitz MI for the WASID Study Group. Risk factor status and vascular events in
patients with symptomatic intracranial stenosis. Neurology 2007;69;2063-2068.
50. Labresh KA, Reeves MJ, Frankel MR, Albright D, and Schwamm LH. Hospital
treatment of patients with ischemic stroke or transient ischemic attack with Get With The
Guidelines. Archives of Internal Medicine. Feb 25, 2008;168(4):411-17.
51. Kleindorfer D, Miller R, Sailor-Smith S, Moomaw CJ, Khoury J, Frankel M.
The challenges of community-based research: the beauty shop stroke education project.
Stroke. 2008 Aug;39(8):2331-5.
52. Waddy SP, Cotsonis G, Lynn MJ, Frankel MR, Chaturvedi S, Williams JE, Chimowitz
M. Racial Differences in Vascular Risk Factors and Outcomes of Patients With
Intracranial Atherosclerotic Arterial Stenosis. Stroke. 2008 Oct 2. [Epub ahead of print]
53. Schwamm LH, Fonarow GC, Reeves MJ, Pan W, Frankel MR, Smith EE, Ellrodt G,
Cannon CP, Liang L, Peterson E, Labresh KA. Get With the Guidelines-Stroke is
associated with sustained improvement in care for patients hospitalized with acute stroke
or transient ischemic attack. Circulation. 2009 Jan 6;119(1):107-15.
54. Schwamm LH, Audebert HJ, Amarenco P, Chumbler NR, Frankel MR, George MG,
Gorelick PB, Horton KB, Kaste M, Lackland DT, Levine SR, Meyer BC, Meyers PM,
Patterson V, Stranne SK, White CJ, and on behalf of the American Heart Association
Stroke Council; Council on Epidemiology and Prevention; Interdisciplinary Council on
Peripheral Vascular Disease; and the Council on Cardiovascular Radiology and
Intervention . Recommendations for the Implementation of Telemedicine Within Stroke
Systems of Care. A Policy Statement From the American Heart Association
Stroke. Published online, May 7, 2009, doi:10.1161/STROKEAHA.109.192361
55. Rhoney DH, Coplin WM, Lin Y, Frankel M, Lyden PD, Levine SR.Time of day,
outcome, and response to thrombolytic therapy: the National Institute of Neurological
Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Trial
experience. J Stroke Cerebrovasc Dis. 2010 Jan;19(1):40-8.
56. Famakin B, Weiss P, Hertzberg V, McClellan W, Presley R, Krompf K, Karp H, Frankel
MR. Hypoalbuminemia predicts acute stroke mortality: Paul Coverdell Georgia Stroke
Registry. J Stroke Cerebrovasc Dis. 2010 Jan;19(1):17-22
CV: Michael R. Frankel, M.D.
Page - 17
57. Schwamm LH, Reeves MJ, Pan W, Smith EE, Frankel MR, Olson D, Zhao X, Peterson
E, Fonarow GC. Race/ethnicity, quality of care, and outcomes in ischemic stroke.
Circulation. 2010 Apr 6;121(13):1492-501
58. Menon BK, Frankel MR, Liang L, Labresh KA, Ellrodt G, Hernandez AF, Fonarow GC,
Schwamm LH, Smith EE; on behalf of the Get With The Guidelines–Stroke Steering
Committee and Investigators Rapid Change in Prescribing Behavior in Hospitals
Participating in Get With The Guidelines-Stroke After Release of the Management of
Atherothrombosis With Clopidogrel in High-Risk Patients (MATCH) Clinical Trial
Results. Stroke. 2010 Jul 15.
59. Reeves MJ, Gargano J, Maier KS, Broderick JP, Frankel M, LaBresh KA, Moomaw CJ,
Schwamm L.. Patient-level and hospital-level determinants of the quality of acute stroke
care: a multilevel modeling approach. Stroke 2010 Dec;41(12):2924-31.
60. Nahab F, Le A, Judd S, Frankel MR, Ard J, Newby PK, Howard VJ. Racial and
geographic differences in fish consumption: the REGARDS study. Neurology. 2011 Jan
11;76(2):154-8. Epub 2010 Dec 22.
61. Anderson ER, Smith B, Ido M, Frankel M. Remote Assessment of Stroke Using the
iPhone 4. J Stroke Cerebrovasc Dis. 2011 Oct 20. [Epub ahead of print]
PMID:22018507
62. Nahab F, Kingston C, Frankel MR, Dion JE, Cawley CM, Mitchell B, Hammonds LP,
Ayala L, Tong FC. Early Aggressive Medical Management for Patients with Symptomatic
Intracranial Stenosis. J Stroke Cerebrovasc Dis. 2011 Jul 25. [Epub ahead of print]
63. Gupta R, Horev A, Nguyen T, Gandhi D, Wisco D, Glenn BA, Tayal AH, Ludwig B,
Terry JB, Gershon RY, Jovin T, Clemmons PF, Frankel MR, Cronin CA, Anderson AM,
Hussain MS, Sheth KN, Belagaje SR, Tian M, Nogueira RG. Higher volume
endovascular stroke centers have faster times to treatment, higher reperfusion rates and
higher rates of good clinical outcomes. J Neurointerv Surg. 2012 Jul 25. [Epub ahead of
print]
64. SPS3 Investigators, Benavente OR, Hart RG, McClure LA, Szychowski JM, Coffey CS,
Pearce LA. Effects of clopidogrel added to aspirin in patients with recent lacunar stroke.
N Engl J Med. 2012 Aug 30;367(9):817-25.
65. Sun CH, Nogueira RG, Glenn BA, Connelly K, Zimmermann S, Anda K, Camp D,
Frankel MR, Belagaje SR, Anderson AM, Isakov AP, Gupta R. "Picture to puncture": a
novel time metric to enhance outcomes in patients transferred for endovascular
reperfusion in acute ischemic stroke. Circulation. 2013 Mar 12;127(10):1139-48.
66. Horn CM, Sun CH, Nogueira RG, Patel VN, Krishnan A, Glenn BA, Belagaje SR,
Thomas TT, Anderson AM, Frankel MR, Schindler KM, Gupta R. Endovascular
CV: Michael R. Frankel, M.D.
Page - 18
Reperfusion and Cooling in Cerebral Acute Ischemia (ReCCLAIM I). J Neurointerv
Surg. 2013 Mar 6. [Epub ahead of print]
67. Rangaraju S, Owada K, Noorian R, Nogueira RG, Nahab F, Glenn BA, Belagaje SR,
Anderson AM, Frankel MR, Gupta R. Comparison of Final Infarct Volumes in Patients
Who Received Endovascular Therapy or Intravenous Thrombolysis for Acute Intracranial
Large-Vessel Occlusions. JAMA Neurol, Published online May 13, 2013.
[doi:10.1001/jamaneurol.2013.413.]
68. Woo D, Rosand J, Kidwell C, McCauley J, Osborne J, Brown MW, West SE,
Rademacher EW, Waddy S, Roberts JN, Koch S, Gonzales NR, Sung G, Kittner S,
Birnbaum L, Frankel M, Testai FE, Hall C, Elkind M, Flaherty M, Coull B, Chong JY,
Warwick T, Malkoff M, James ML, Ali LK, Worrall B, Jones F, Watson T, Leonard A,
Martinez R, Sacco R and Langefeld CD. The Ethnic/Racial Variations of Intracerebral
Hemorrhage (ERICH) Study Protocol. Stroke, published online Sept 10, 2013.
69. Ivan C. Rokos, Lee H. Schwamm, Madeleine Konig, Mary-Beth Malcarney, Katie B.
Horton, Jeffrey Ranous, A. Gray Ellrodt, Steven A. Farmer, Michael R. Frankel, T.
Bruce Ferguson, David C. Goff, Jr, Loren Hiratzka, Alice K. Jacobs on behalf of the
American Heart Association Advocacy Coordinating Committee. Variable Impact of
State Legislative Advocacy on Registry Participation and Regional Systems of Care
Implementation: A Policy Statement From the American Heart Association. Circulation.
Published on line Sept 16, 2013.
70. Kass-Hout T, Kass-Hout O, Sun CH, Kass-Hout T, Belagaje S, Anderson A, Frankel M,
Gupta R, Nogueira R. Clinical, angiographic and radiographic outcome differences
among mechanical thrombectomy devices: initial experience of a large-volume center. J
Neurointerv Surg. 2014 Mar 21. doi: 10.1136/neurintsurg-2013-011037. [Epub ahead of
print]
71. Bian F, Simon RP, Li Y, David L, Wainwright J, Hall CL, Frankel M, Zhou A.
Nascent proteomes in peripheral blood mononuclear cells as a novel source for biomarker
discovery in human stroke. Stroke. 2014 Apr;45(4):1177-9. doi:
10.1161/STROKEAHA.113.004576. Epub 2014 Feb 20.
72. Sun CH, Connelly K, Nogueira RG, Glenn BA, Zimmermann S, Anda K, Camp D, Gaunt
S, Pallard H, Eckenroth M, Frankel MR, Belagaje SR, Anderson AM, Nahab F, Yepes
M, Gupta R. ASPECTS decay during inter-facility transfer predicts patient outcomes in
endovascular reperfusion for ischemic stroke: a unique assessment of dynamic
physiologic change over time. J Neurointerv Surg. 2014 Mar 26. doi:
10.1136/neurintsurg-2013-011048. [Epub ahead of print]
73. Belagaje SR, Sun CH, Nogueira RG, Glenn BA, Wuermser LA, Patel V, Frankel MR,
Anderson AM, Thomas TT, Horn CM, Gupta R. Discharge disposition to skilled nursing
facility after endovascular reperfusion therapy predicts a poor prognosis. J Neurointerv
CV: Michael R. Frankel, M.D.
Page - 19
Surg. 2014 Jan 17. doi: 10.1136/neurintsurg-2013-011045. [Epub ahead of print]
74. Derdeyn CP, Chimowitz MI, Lynn MJ, Fiorella D, Turan TN, Janis LS, Montgomery J,
Nizam A, Lane BF, Lutsep HL, Barnwell SL, Waters MF, Hoh BL, Hourihane JM, Levy
EI, Alexandrov AV, Harrigan MR, Chiu D, Klucznik RP, Clark JM, McDougall CG,
Johnson MD, Pride GL Jr, Lynch JR, Zaidat OO, Rumboldt Z, Cloft HJ; Stenting and
Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis
Trial Investigators. Aggressive medical treatment with or without stenting in high-risk
patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised
trial. Lancet. 2014 Jan 25;383(9914):333-41. doi: 10.1016/S0140-6736(13)62038-3.
Epub 2013 Oct 26.
75. Rangaraju S, Liggins JT, Aghaebrahim A, Streib C, Sun CH, Gupta R, Nogueira R,
Frankel M, Mlynash M, Lansberg M, Albers G, Jadhav A, Jovin TG. Pittsburgh
outcomes after stroke thrombectomy score predicts outcomes after endovascular therapy
for anterior circulation large vessel occlusions. Stroke. 2014 Aug;45(8):2298-304. PMID:
25005445
76. Rangaraju S, Aghaebrahim A, Streib C, Sun CH, Ribo M, Muchada M, Nogueira R,
Frankel M, Gupta R, Jadhav A, Jovin TG. Pittsburgh Response to Endovascular therapy
(PRE) score: optimizing patient selection for endovascular therapy for large vessel
occlusion strokes. J Neurointerv Surg. 2014 Oct 15, PMID: 25320054
77. Pearce LA, McClure LA, Anderson DC, Jacova C, Sharma M, Hart RG, Benavente OR;
SPS3 Investigators. Effects of long-term blood pressure lowering and dual antiplatelet
treatment on cognitive function in patients with recent lacunar stroke: a secondary
analysis from the SPS3 randomised trial. Lancet Neurol. 2014 Dec;13(12):1177-85.
78. Wright DW, Yeatts SD, Silbergleit R, Palesch YY, Hertzberg VS, Frankel M, Goldstein
FC, Caveney AF, Howlett-Smith H, Bengelink EM, Manley GT, Merck LH, Janis LS,
Barsan WG; NETT Investigators. Very early administration of progesterone for acute
traumatic brain injury.N Engl J Med. 2014 Dec 25;371(26):2457-66.
79. Ido MS, Bayakly R, Frankel M, Lyn R, Okosun IS. Administrative data linkage to
evaluate a quality improvement program in acute stroke care, Georgia, 2006-2009. Prev
Chronic Dis. 2015 Jan 15;12:E05.
80. Kass-Hout T, Kass-Hout O, Sun CH, Kass-Hout T, Belagaje SR, Anderson AM, Frankel
MR, Gupta R, Nogueira RG. Periprocedural cost-effectiveness analysis of mechanical
thrombectomy for acute ischemic stroke in the stent retriever era. Interv Neurol. 2015
Mar;3(2):107-13.
81. Kass-Hout T, Kass-Hout O, Sun CH, Kass-Hout T, Belagaje S, Anderson A, Frankel M,
Gupta R, Nogueira R. Clinical, angiographic and radiographic outcome differences
among mechanical thrombectomy devices: initial experience of a large-volume center. J
CV: Michael R. Frankel, M.D.
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Neurointerv Surg. 2015 Mar;7(3):176-81
82. Haussen DC, Lima A, Frankel M, Anderson A, Belagaje S, Nahab F, Rangaraju S,
Nogueira RG. Sulcal effacement with preserved gray-white junction: a sign of reversible
ischemia. Stroke. 2015 Jun;46(6):1704-6.
83. Kass-Hout T, Kass-Hout O, Sun CH, Kass-Hout T, Belagaje SR, Anderson AM, Frankel
MR, Gupta R, Nogueira RG. Periprocedural cost-effectiveness analysis of mechanical
thrombectomy for acute ischemic stroke in the stent retriever era. Interv Neurol. 2015
Mar;3(2):107-13
84. Rangaraju S, Streib C, Aghaebrahim A, Jadhav A, Frankel M, Jovin TG. Relationship
Between Lesion Topology and Clinical Outcome in Anterior Circulation Large Vessel
Occlusions. Stroke. 2015 Jul;46(7):1787-92.
REVIEW ARTICLES
Frankel MR, Ischemic Cerebrovascular Disease. Neurosurgical Consultations Vol. 3, #23,
1992.
Qureshi A, Dawson R, Frankel MR and Stern B. Recent Advances in the Management of
Vasospasm in Patients with Subarachnoid Hemorrhage. Neurologist, Jan 96.
Qureshi A and Frankel MR. Diagnosis and Management of Subarachnoid Hemorrhage.
Journal of Heart Disease and Stroke, Sept, Oct 1994.
Frankel MR. Intravenous t-PA for Acute Ischemic Stroke. Neurologist, Sep 96.
Seestedt, Jr RC and Frankel MR, Intracerebral Hemorrhage. Current Treatment Options in
Neurology, 1999, 1:127-137.
Sanders KA and Frankel MR. Stroke care and prevention in Georgia: current status and
challenges. Journal of the Medical Association of Georgia. February, 2001: 29-31.
Thambisetty M, Newman N, Glass J and Frankel MR. A practical approach to the diagnosis
and management of MELAS: Case report and review. The Neurologist 8:302-312:2002.
Frankel MR. Acute Stroke. In: Continuum. American Academy of Neurology CME
publication. Volume 9, number 2, April 2003, pgs 31 – 52.
Frankel MR, Wityk RJ, Pullicino P, and Chan R. Pharmacology of Stroke. In: Continuum.
American Academy of Neurology CME publication. Lippincott Williams and Wilkins Press.
Volume 9, number 2, April 2003, pgs 83 – 96.
JOURNALS EDITED:
CV: Michael R. Frankel, M.D.
Page - 21
Frankel MR and Levine SR. TPA for Acute Stroke: Perspectives after 5 years of use.
Seminars in Cerebrovascular Disease. 2001:1;117-198.
Frankel MR and Levine SR. TPA for Acute Stroke: Perspectives after 5 years of use.
Journal of Cerebrovascular Disease and Stroke. 2002:11;119-203.
BOOK CHAPTERS:
Frankel MR and Mackay B. Large Vessel Occlusive Disease. In: The Medical
Management of the Surgical Patient. Lippincott, Edited by Lubin, M., 1995. Revised
2006.
Frankel MR and Chimowitz M. Acute Stroke. In: Emergency Neurology, Principles and
Practice. Cambridge Press 1999.
Frankel, MR, Arora A, and Badjatia N. Thrombolytic Therapy. In: Neurological
Therapeutics, Principles and Practice. Martin Dunitz Publishers. The Liversy House,
London. Volume 1, 2003:pgs 408 – 419. Revised for 2nd edition, published in 2006.
Frankel, MR and Bichsel, J. Thrombolytic therapy for TIA and mild stroke. In:
Transient Ischemic Attacks. Blackwell Publishing. 2004; pgs 348 - 364.
CDC PUBLICATIONS:
Frankel MR, Hinchey J, Schwamm LH, Wall H, Rose KM, George MG, McGruder HF,
Liban A, Croft JB. Prehospital and Hospital Delays After Stroke Onset --- United States,
2005—2006. MMWR. 2007;56(19):474-478.
SYMPOSIUM CONTRIBUTIONS:
Proceedings from The Rapid Identification and Treatment of Acute Ischemic
Stroke,NINDS,12/96. Web site:
http://www.ninds.nih.gov/health_and_medical/pubs/strokeworkshop.htm
BOOK REVIEWS:
Journal of Neurosurgery, Feb 1994. Review of Transcranial Doppler: A Clinical
Approach by Babikian, et al.
Journal of Neurosurgery. Review of Neurosonology by Tegeler, et al, 1996.
Journal of Neurosurgery. Review of Handbook of Transcranial Doppler by McCartney et
al. 1997.
CV: Michael R. Frankel, M.D.
Page - 22
Neurology. Review of Clinical Practice of Critical Care Neurology by Wijdicks EFM.
April, 1998.
MONOGRAPHS:
Frankel MR, Kothari R. Acute Ischemic Stroke: A New Paradigm. Emory University
School of Medicine, Continuing Medication Education Program. Distributed to
Neurologists and Emergency Physicians in the U.S. in 1998. Produced by Syner Med and
Sponsored by Genentech, Inc.
OTHER PUBLICATIONS:
LETTERS TO EDITOR:
Frankel MR, for the NINDS t-PA Stroke Study Group: Thrombolytic therapy in acute
ischemic stroke. (Letter) New Engl J Med 1997; 336:65.
8/2015