2010 Epithelium Lecture-Kim_opt

download 2010 Epithelium Lecture-Kim_opt

of 53

Transcript of 2010 Epithelium Lecture-Kim_opt

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    1/53

    08,3/%88:08$06:03.0

    0/.,8944

    590:2$05902-07

    $20/$.

    28:2.0/:

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    2/53

    7%88:4;03904940,;0(

    988:0 8,347,30/,70,94341.084774:5841.089,91:3.9433,

    .447/3,90/2,3307945071472430472470850.1.1:3.9438

    %88:08 .42-30941472,7071:3.943,:398.,0/#$%:890988:08,7090-,8.1:3.943,:3987085438-0147 2,39,33-4/1:3.9438

    %88:08

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    3/53

    $%$$&$590:2590,988:0

    4330.9;0988:0:8.0

    07;4:8988:044/(

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    4/53

    fnfnf

    ffnfffn

    f

    9n %fffffff

    nf%fnffnfnf

    @f %f

    n %nn

    n fnnf

    nnnfn

    /:.9

    $0.70947547943

    :36::07,,730749/!

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    5/53

    099075

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    6/53

    590, 33.0841

    $3 3908930

    :950,07841.089/11070398,508 $30,07419,.4:23,7.08

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    7/53

    590,.08

    472,;,8.:,7800989,9/110733:2-0741.0,078,3/ 8,504190.08/0503/34390988:01:3.9438

    70897:.9:7,,3/1:3.943,54,70/, ,;0,5.,,907,,3/-,8,/42,38- $420.0870;0,897:.9:7,850.,,943841901700,5.,.0

    8:71,.0

    700/940907-80;07,850.,,9438343,8903907.0:,7:3.9438,3/,70-4:3/9490:3/073.4330.9;0988:0;,90-,802039202-7,3047-,8,,23,

    70.,5,-0417030,,3/700307,943

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    8/53

    590,.08 472,;,8.:,7800989,9/110733:2-0741.0,078

    ,3/8,504190.08/0503/34390988:01:3.9438

    70897:.9:7,,3/1:3.943,54,70/, ,;0,5.,,907,,3/-,8,/42,38- $420.0870;0,897:.9:7,850.,,943841901700,5.,.08:71,.0

    700/940907-80;07,850.,,9438343,8903907.0:,7:3.9438,3/,70-4:3/9490:3/073.4330.9;0

    988:0;,90-,802039202-7,3047-,8,,23,

    70.,5,-0417030,,3/700307,943

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    9/53

    ,881.,94341590:2

    !80:/4897,910/

    .4:23,7#0857,947

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    10/53

    !80:/4897,910/590:2

    07803-,:25

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    11/53

    $25086:,24:80590:203/490:2,3/208490:2

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    12/53

    3/490:208490:2$250$6:,24:8590:2

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    13/53

    $250:-4/,590:2

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    14/53

    $2504:23,7590:2

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    15/53

    $250.4:23,70590:2

    3390:9:203

    :203

    %4,07841824492:8.0

    4390,

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    16/53

    5.,0$:71,.0$50.,,9438

    $97,90/47/07.74;

    4-09.0

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    17/53

    .74;47041,.931,20398

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    18/53

    $97,910/$6:,24:8590:2

    34307,930/07,930/

    07803-,:25

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    19/53

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    20/53

    %7,38943,590:2

    :7490:2

    07803-,:25

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    21/53

    %7,38943,590:2 :7490:230890:73,797,.9:70907-,//07,3/:7097,

    0843908:71,.0,7041903/420:2-70,8,50/,3/8420.0870;0,

    943:.0

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    22/53

    !80:/4897,910/4:23,7590:2

    94-09.08,3/.,#0857,947590:2

    1742'070

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    23/53

    ,5.,0$:71,.0$50.,,9438 .470412.749:-:083,77,302039,43020

    .,

    ,8,-4/084-09.08

    #0857,9470590:2

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    24/53

    43020

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    25/53

    30387085438-0147908/3

    -079809,!

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    26/53

    430370,908553470,934943419043020

    %0,43020889,-0/-33

    57490389,9570;039902.749:-:081742

    8/35,890,.4907

    %0390147.08.70,90/-/303

    ,99,.0/944302.749:-:0,3/,3

    43,3,/,.0392.749:-:08.,3.,:80

    90,4302094-03/

    742'070

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    27/53

    303010.98322490,

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    28/53

    %4950841,5.,.08:71,.0850.,,9438

    .74;,3/.,.74;

    ,

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    29/53

    590,.08 472,;,8.:,7800989,9/110733:2-0741.0,078,3/8,50

    4190.08/0503/34390988:01:3.9438

    70897:.9:7,,3/1:3.943,54,70/, ,;0,5.,,907,,3/-,8,/42,38- $420.0870;0,897:.9:7,850.,,943841901700,5.,.0

    8:71,.0

    700/940907-80;07,850.,,9438343,8903907.0:,7:3.9438,3/,70-4:3/9490:3/073.4330.9;0988:0;,90-,802039202-7,3047-,8,,23,

    70.,5,-0417030,,3/700307,943

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    30/53

    590,.08 472,;,8.:,7800989,9/110733:2-0741.0,078,3/8,504190.08/0503/3

    4390988:01:3.9438

    70897:.9:7,,3/1:3.943,54,70/, ,;0,5.,,907,,3/-,8,/42,38- $420.0870;0,897:.9:7,850.,,943841901700,5.,.08:71,.0

    700/940907-80;07,850.,,9438343,8903907.0:,7:3.9438,3/,70-4:3/9490:3/073.4330.9;0988:0;,90-,802039202-7,3047-,8,,23,

    70.,5,-0417030,,3/700307,943

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    31/53

    %0897:.9:7089,94/90.08940907,3/

    ,99,.08900590:294

    90.4330.9;0988:0,70

    3907.0:,7:3.9438

    ,802039202-7,30-,8,,23,

    3907.0:,7:3.9438.,343-04-807;0/,990

    00.97432.748.4500;0,3/%,99092.748.450

    0;0

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    32/53

    ,.:,,/07038 /082484208,3/ 390720/,90,20398

    082484208,70%;8-0

    ,99092.748.4500;0

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    33/53

    ,.:,/07038/08248420

    00

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    34/53

    082484208,3/390720/,90,20398

    -079809,5

    082484208807;0,8

    $549,99,.20398908147

    ,/,.039.0202-7,3083.4738908147390720/,90

    1,20398

    1742

    '070

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    35/53

    ,802039202-7,30-,8,,23,

    02/0824842081:3.94394,3.470590,.089490.4330.9;0988:0;,-,802039

    202-7,30-,8,,23,

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    36/53

    48841/082484201:3.9438.,:8089073$3847/078

    !025:8$05,7,9434105/072,.0817420,.4907,.,39488.,:80/-48841/082484201:3.9438

    5/072488-:48,$05,7,9434105/0728174290/0728/:094-89073390-,802039

    202-7,30.,:80/-48841,3.4731,20398,3/02/082484208

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    37/53

    3907.0:,7:3.9438 :3.943,4250

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    38/53

    43:,,/07038390720/,90:3.943

    #48809,

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    39/53

    43:,,/07038,.:,,/07038

    W 390720/,90:3.943

    W /073:3.943W ,/0738

    W 30/94,.93

    1,20398W /0843-09

    W 08248420

    W /073:3.943

    W ,/0738

    W 30/94

    390720/,901,20398

    W $549,/073

    :3.943

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    40/53

    43:,4..:/03899:3.943807;08,8,800.9;050720,-9-,7707

    :36::07,,730749/!

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    41/53

    43:,4..:/03899:3.943

    -079809,5

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    42/53

    700017,.9:705705,7,9434143:,4..:/038

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    43/53

    0:8,5:3.943 .422:3.,93:3.943

    $43303 8:-:398,8802-0941472,433043

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    44/53

    ,5:3.943

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    45/53

    3907.0:,7:3.9438

    $97:.9:70 :3.943

    090

    43:,4..:/03899:3.943

    43:,,/07038390720/,90:3.943

    $00.9;050720,-9,7707

    094.0,/0843-093.473890147,.93

    $549:3.943

    ,.:,,/07038/08248420

    02/08248420

    094.0,/084385493.473890147390720/,901,20398

    3.4780590,.089490

    -,8,,23,

    ,5:3.943

    0:8,5:3.943 094.0.422:3.,9438

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    46/53

    590,.08

    472,;,8.:,7800989,9/110733:2-0741.0,078,3/8,504190.08/0503/34390988:01:3.9438

    70897:.9:7,,3/1:3.943,54,70/

    , ,;0,5.,,907,,3/-,8,/42,38- $420.0870;0,897:.9:7,850.,,943841901700,5.,.0 8:71,.0

    700/940907-80;07,850.,,9438343,8903907.0:,7:3.9438,3/,70-4:3/9490:3/073.4330.9;0988:0;,90-,802039202-7,3047-,8,,23,

    70.,5,-0417030, ,3/ 700307,943

    343850.,0/0590:2,.08850.,0/0590:2 8902.08

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    47/53

    590:2%508 8250897,910/580:/4897,910/

    5.,.08:71,.0850.,,9438.74; ,.931,20398

    , 2.749:-:08/3038

    3907.0:,7:3.9438

    43:,4..:/03899:3.943 7/08,3/744;08

    80,3907.0:,785,.08 $00.9;050720,-9-,7707

    43:,,/07038390720/,90:3.943 ,.931,20398.094.0,/0843

    ,.:,,/07038/08248420 390720/,901,20398 ,99,.20395,6:08549

    02/08248420 ,99,.080590:294-,8,,23,

    0:8,5:3.943 .4330438 .094.0.422:3.,943

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    48/53

    590,.081472$0.70947,3/8

    ,3/874:53841.08850.,0/14780.70943

    $0.70943 890574.088-.82,240.:08,709,03:5,3/97,3814720/-397,.0:,7-4839088394,2470

    .4250574/:.99,98903,.9;0700,80/174290.0

    4.730/:.98,3/03/4.730/:.9088,3/8

    $0.709 7 590, .08

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    49/53

    $0.70947590,.08

    1 / / /

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    50/53

    0;0452039413/4.730,3/4.730,3/8

    :36:07,,730749/!

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    51/53

    $0.70947&398,3/,3/:,708

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    52/53

    %4$0.70947!,9,8

    4.948

    8

    #0:,90/$0.70943 $0.709477,3:08,..:2:,903.08,3/907,3:0.4390398700,80/

    -04.9488:543892:,943

    43899:9;0$0.70943%0

    80.70947574/:.98349.43.0397,90/3947,3:08-:98700,80/.4393:4:8382,;08.08

  • 8/6/2019 2010 Epithelium Lecture-Kim_opt

    53/53