2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have...

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2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) June 13, 2022 10:14 AM

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Spironolactone Potassium sparing diuretic Antiandrogen Aldosterone receptor antagonist Androgen receptor antagonist Testosterone synthesis inhibitor Antihypertensive Heart failure treatment

Transcript of 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have...

Page 1: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

2004-2005Pharmacology Review

of Everything(Principles, Cardiovascular and Respiratory drugs have been

updated)

May 4, 202311:11 PM

Page 2: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Spectinomycin

AntibioticBacteriostatic protein synthesis

inhibitor

30S ribosome

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Spironolactone

Potassium sparing diureticAntiandrogen

Aldosterone receptor antagonistAndrogen receptor antagonist

Testosterone synthesis inhibitorAntihypertensive

Heart failure treatment

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St. John’s Wort

Dietary supplement

Antidepressant

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Streptokinase

Thrombolytic

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Streptomycin

Aminoglycoside antibioticBactericidal protein synthesis

inhibitor

30S ribosomeFreezes initiation

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Succinylcholine

Paralytic

Depolarizing blockerParalyzes skeletal muscles

Bronchoconstrictor

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Sucralfate

Antiulcer

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Sufentanil

OpioidGeneral anaesthetic

Intravenous anaesthetic

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Sulfacetamide

Sulfonamide antibioticMicrobial nucleic acid

and protein synthesis inhibitor

Inhibits dihydropteroate synthetaseTopical

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Sulfadoxine

Sulfonamide antibioticMicrobial nucleic acid

and protein synthesis inhibitor

Dihydropteroate synthetase inhibitor

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Sulfamethoxazole

Sulfonamide antibioticMicrobial nucleic acid

and protein synthesis inhibitor

Inhibits dihydropteroate synthetase

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Sulfasalazine

Disease modifyinganti-rheumatic drug (DMARD)

Metabolized to sulfonamide+ salicylate (NSAID)

Treatment of IBD

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Sulfinpyrazone

Uricosuric

Anti-gout

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Sulfisoxazole

Sulfonamide antibioticNucleic acid and

protein synthesis inhibitor

Inhibits dihydropteroate synthetase

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Sulfonamides

AntibioticsNucleic acid and

protein synthesis inhibitors

Inhibit dihydropteroate synthetase

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Sulindac

NSAIDAnalgesic, Anti-inflammatory,

Antipyretic

Cyclooxygenase inhibitor

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Suramin

Tropical antiparasitic

Treatment of African Trypanosomiasis

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Tacrolimus

ImmunosuppressiveAntineoplastic

Binds FKBP (FK506 binding protein)

Inhibits calcineurin

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Tamoxifen

Antineoplastic Antiestrogen

Estrogen receptor anatagonist

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Tegaserod

IBS treatment

5HT4 receptor agonist

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Telmisartan

Antihypertensive

Angiotensin receptor blocker(ARB)

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Temazepam

Sedative/Hypnotic

Benzodiazepine Acts on GABAA receptor

complex

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Tenecteplase

Thrombolytic

Tissue plasminogen activator (tPA)

Page 25: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Terazosin

Sympatholytic1 adrenergic antagonist

AntihypertensiveTreatment for benign prostatic

hypertrophy

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Terbinafine

Allylamine antifungal

Inhibits ergosterol synthesis by inhibiting squalene epoxidase

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Terbutaline

Sympathomimetic2 adrenergic agonist

Short acting bronchodilator Tocolytic

Uterine relaxant

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Testosterone

Androgen

Natural male gonadal steroid

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Testosterone cypionate

Androgen

Synthetic depot

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Testosterone enanthate

Androgen

Synthetic depot

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Testosterone propionate

Androgen

Synthetic depot

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Tetracaine

Local anaesthetic

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Tetracycline

AntibioticBacteriostatic protein synthesis

inhibitor Antiulcer

30S ribosomePrevents aminoacyl tRNA attachment

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Thalidomide

AntineoplasticLeprosy treatment

Anti-angiogenicAnti-TNF

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Theophylline

Bronchodilator

MethylxanthinePhosphodiesterase inhibitor

Used in asthma

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Thiabendazole

Antihelminthic

Treatment of intestinal roundworms

Page 37: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

6-Thioguanine

Antineoplastic

Antimetabolite (“pseudofeedback inhibition” of

HGPRT and PRP – purine synthesis)

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Thiopental

General Anaesthetic

Ultra-short-acting barbiturate

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Thioridazine

Antipsychotic

Phenothiazine

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Thiotepa

Antineoplastic

Alkylating agent

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Thiothixene

Antipsychotic

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Thrombopoietin

Cytokine

Platelet synthesis stimulator

Page 43: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Thromboxane A2 (TXA2)

Autacoid

Promotes platelet aggregation Cyclooxygenase product of arachidonate metabolism

Page 44: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Thyrotropin-releasing Hormone (TRH)

Hypothalamic hormone

Stimulates release of thyroid stimulating hormone (TSH) from

the anterior pituitary

Page 45: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

ThyrotropinThyroid-stimulating Hormone

(TSH)

Anterior pituitary hormone

Stimulates production of thyroxine (T4), triiodothyronine

(T3) and thyroglobulin

Page 46: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Ticarcillin

Penicillin antibioticCell wall synthesis inhibitor

Anti-pseudomonal penicillinInhibits peptidoglycan cross-

linking

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Ticlopidine

Antiplatelet

ADP receptor antagonist

Page 48: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Timolol

Sympatholytic adrenergic antagonist

AntihypertensiveGlaucoma treatment

Anti-anginalBronchoconstrictor

Page 49: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Tissue plasminogen activators

Thrombolytics

alteplase, reteplase, tenecteplase

Page 50: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Tobramycin

Aminoglycoside antibioticBactericidal protein synthesis

inhibitor

30S ribosomeFreezes initiation

Page 51: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Tocainide

Class I antiarrhythmic

Na+ channel blocker(activated channels)

Page 52: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Tolbutamide

Oral hypoglycemic

SulfonylureaInsulinotropic

Page 53: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Tolterodine

Anticholinergic

Muscarinic receptor antagonistPrevents urination

Page 54: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Toremifene

Estrogen antagonist

Selective estrogen receptor modulator (SERM)

Page 55: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Tosemide

Loop diuretic

Na-K-2Cl symporter inhibitor

Page 56: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Trandopril

Antihypertensive

Converting enzyme inhibitor

Page 57: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Tranylcypromine

Antidepressant

Monoamine oxidase inhibitor (MAO-I)

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Trastuzumab

Antineoplastic

Anti-HER2 antibody

Page 59: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Triamcinolone

AdrenocorticosteroidGlucocorticoid

Anti-inflammatory steroidInhaled

Page 60: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Triamterene

Potassium sparing diuretic

Sodium channel inhibitorAntihypertensive

Page 61: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Triazolam

Sedative/Hypnotic

Benzodiazepine Acts on GABAA receptor

complex

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Trifluoperazine

Antipsychotic

Phenothiazine

Page 63: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Trifluridine

Antiherpes

Pyrimidine analogPhosphorylated to inhibitor of

viral DNA polymerase

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Trihexyphenidyl

Antiparkinson

Antimuscarinic

Page 65: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Trimethaphan

SympatholyticAnticholinergic

Nicotinic antagonistAntihypertensive

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Trimethoprim

AntibioticProtein and nucleic acid

synthesis inhibitor

Inhibits bacterial dihydrofolate reductase

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Tripelennamine

Classical antihistamine

H1 antagonist

Page 68: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Tubocurarine

Paralytic

Paralyzes skeletal muscles

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Tumor necrosis factor

CytokineAntineoplastic

Page 70: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Tyramine

Indirect sympathomimetic

VasoconstrictorVasopressor

Page 71: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Ultralente insulin

HormoneInsulin analogue

Long acting

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Urokinase

Thrombolytic

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Valacyclovir

Antiherpes

Purine analogPhosphorylated to inhibitor of

viral DNA polymerase

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Valsartan

Antihypertensive

Angiotensin receptor blocker(ARB)

Page 75: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Valganciclovir

Antiherpes

Purine analogPhosphorylated to inhibitor of

viral DNA polymerase

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Valproic acid

Anticonvulsant

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Valsartan

Antihypertensive

Angiotensin receptor blocker(ARB)

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Vancomycin

AntibioticInhibits cell wall synthesis

Not a lactam

Page 79: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Arginine vasopressin(Antidiuretic hormone;

ADH)

Hypothalamic (posterior pituitary) hormone

AntidiureticVasoconstrictor

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Vecuronium

Paralytic

Paralyze skeletal muscles

Page 81: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Verapamil

Class IV antiarrhythmicAntihypertensive

L-type Ca2+ channel blocker Antianginal

Page 82: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Vigabatrin

Anticonvulsant

Irreversible GABA aminotransferase inhibitor

Page 83: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Vinblastine

Antineoplastic

Vinca alkaloidNatural product

Page 84: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Vincristine

Antineoplastic

Vinca alkaloidNatural product

Page 85: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Voriconazole

Triazole antifungal

Inhibits synthesis of ergosterol by inhibiting lanosterol 14

demethylase

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Warfarin

Anticoagulant

Vitamin K synthesis inhibitor

Page 87: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Zafirlukast

Leukotriene inhibitor

LTR1 and LTD4 antagonistAsthma treatment

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Zalcitabine

Antiretroviral

Nucleoside reverse transcriptase inhibitor (NRTI)

Dideoxycytidine (ddC)

Page 89: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Zanamivir

Antiviral

Inhibits neuraminidaseand decreases viral release

Treatment of Influenza A & B

Page 90: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Zidovudine

Antiretroviral

Nucleoside reverse transcriptase inhibitor (NRTI)

Azidothymidine (AZT)

Page 91: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Zileuton

Leukotriene inhibitor

5-lipoxygenase inhibitorUsed in asthma

Page 92: 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

Zolpidem

Sedative/Hypnotic

Non-benzodiazepine