13th STAR NETWORK MEETING 2019Integrated and translatIonaltreatment In gastroIntestInal cancer

Chairman: Carlo Aschele

15th November 2019 Hotel NH La Spezia - SPUNRESTRICTED GRANT BY

PRESIDENTCARLO ASCHELE

SCIENTIFIC COMMITTEEALESSANDRO PASTORINOAMALIA MILANOEMANUELA NEGRU

MEETING VENUE Hotel NHVia XX Settembre, 2, 19124 La Spezia - SP

7 ECM / CME have been requested for the following specialties:Oncology, Radiation Oncology, Radiology-Diagnostic, General Surgery, Gastroenterology, Internal Medicine, Nuclear Medicine, Anatomic & Clinical Pathology, Medical Genetics, Biology and Pharmacy

REGISTRATION is free of charge and has to be done online from the website www.mitcongressi.it section: 13th STAR NETWORK MEETING 2019 INTEGRATED AND TRANSLATIONAL TREATMENT IN GASTROINTESTINAL CANCER

PROVIDER AND LOGISTIC SECRETARIATMI&T Srl Viale Carducci, 50 - 40125 Bolognainfo@mitcongressi.it - www.mitcongressi.it

con il patrocinio di

Rete Oncologica Ematologica e Radioterapica della Regione Liguria

DIAR Onco-Ematologicoe

DIAR Chirurgico

13th STAR NETWORK MEETING 2019

8.30 Registration

8.45 Authorities welcome P. Pronzato DIAR Hematology & Oncology Liguria healthcare system

FROM BIOLOGY TO TREATMENT Moderators: R. Canizzaro, G.L. de’ Angelis, A. Ballestrero 9.00 Gastrointestinal stromal tumors and rare sarcomas A. Comandone

9.15 MSI and BRCA testing in selected gastrointestinal tumors: where, when and why? S. Sciallero

9.30 Current and future clinical implications of colorectal cancer molecular landscape F. Di Nicolantonio

9.45 “Anti EGFR pressure” from 1st line to reintroduction and rechallenge in mCRC: biology and clinical perspectives D. Santini

10.00 Questions and Answers RECTAL CANCER Moderators: A. De Paoli, P. Delrio, S. Pucciarelli 10.10 Total neoadjuvant therapy (TNT) for all in LARC: but are we really convinced? R.G. Glynne Jones

10.30 How imaging can inform treatment R. Beets Tan

10.50 Rectal cancer tumor board: navigating through borderline indications to neoadjuvant treatment in LARC: early T3, upper rectal and recto-sigmoidal tumors, very low T2 Chairs: T. Stefanini, T. Scolaro Shooters: A. Pastorino, E. Negru Discussants: B. Barbaro, A. Restivo, G. Masi, M.A. Gambacorta

FOCUS ON LIVER SURGERY IN METASTATIC CRCModerators: R. Pellicci, M. Filauro, F. De Cian11.20 Are the limits of hepatic surgery furtherly expanding? D. Ribero

11.35 Reiterated surgery in the era of biological treatments S. Berti

11.50 Can chemotherapy complement or replace “extreme” surgery C. Cremolini

12.05 Results of chemotherapy trials: is surgery a significant bias? L. Boni

12.20 Questions and Answers

ADVANCED COLORECTAL CANCER Moderators: F. Boccardo, L.M. Repetto12.25 Oxford debate: Role of triplet chemotherapy in routine clinical practice YES A. Falcone NO C. Pinto Referee: G. Beretta

12.55 Anti VEGFR or anti EGFR in 2nd line treatment. Should we really care? S. Lonardi

13.10 Optimizing 3rd line choice A. Zaniboni

13.25 Questions and Answers

13.30 Lunch

BEYOND COLERECTAL CANCER. UPPER GIModerators: A. Ciarmiello, L. Camellini, S. Lonardi14.30 2nd and further line of treatment in gastric cancer. What and what for? M. Di Bartolomeo

14.40 Optimal sequence of treatment in adjuvant (neoadjuvant) and metastatic pancreatic cancer S. Cascinu

14.55 Recent news in medical treatment of hepatocellular carcinomac B. Daniele

15.10 Therapeutic strategy of GEP NET patients resistant to or not eligible for somatostatin analog therapy N. Fazio

15.25 Questions and Answers

THE TIMES THEY ARE A-CHANGIN’. TESTING FOR DPD DEFICIENCY BEFORE STARTING FP’S? Moderators: L. Salvatore, A. Pastorino, M. Clavarezza15.35 How to test/How to read M. Del Re

15.50 Role and timing of rescue M. Crevani

16.00 Pharmacological Basis A. Di Paolo

16.10 Clinical and Guidelines implications L. Salvatore

SUPPORTIVE CARE IN GI CANCERModerators: E. Negru, F. Vaira16.20 Symptoms and pain management in GI malignancies M.Vaglica

16.35 Nutritional approach in GI cancer E. Perini16.45 Conclusion and ECM Test

FACULTY CARLO ASCHELE LA SPEZIAALBERTO BALLESTRERO GENOABRUNELLA BARBARO ROMEREGINA BEETS TAN MAASTRICHT (NL)GIORDANO BERETTA BERGAMOSTEFANO BERTI LA SPEZIAFRANCESCO BOCCARDO GENOALUCA BONI FLORENCELORENZO CAMELLINI LA SPEZIARENATO CANNIZZARO AVIANOSTEFANO CASCINU MILANANDREA CIARMIELLO LA SPEZIAMATTEO CLAVAREZZA GENOAALESSANDRO COMANDONE TURINCHIARA CREMOLINI PISAMARTA CREVANI PAVIABRUNO DANIELE NAPLESGIAN LUIGI DE’ ANGELIS PARMAFRANCO DE CIAN GENOAANTONINO DE PAOLI AVIANOMARZIA DEL RE PISAPAOLO DELRIO NAPLESMARIA DI BARTOLOMEO MILANFEDERICA DI NICOLANTONIO TURINANTONELLO DI PAOLO PISAALFREDO FALCONE PISANICOLA FAZIO MILANMARCO FILAURO GENOAMARIA ANTONIETTA GAMBACORTA ROMEROBERT G. GLYNNE JONES NORTHWOOD (UK)SARA LONARDI PADUAGIANLUCA MASI PISAEMANUELA NEGRU NOVARAALESSANDRO PASTORINO LA SPEZIARICCARDO PELLICCI SAVONAERIKA PERINI SARZANACARMINE PINTO REGGIO EMILIAPAOLO PRONZATO GENOASALVATORE PUCCIARELLI PADUALAZZARO MICHELE REPETTO SANREMOANGELO RESTIVO CAGLIARIDARIO RIBERO CANDIOLO TOLISA SALVATORE ROMEDANIELE SANTINI ROMESTEFANIA SCIALLERO GENOATINDARO SCOLARO LA SPEZIATESEO STEFANINI LA SPEZIAMARINA VAGLICA LA SPEZIAFRANCO VAIRA LA SPEZIAALBERTO ZANIBONI BRESCIA