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Fundamentals of Anterior Segment Reconstruction ASCRS 2016 New Orleans, LA Fundamentals of ASR ASCRS 2016 Thank You Fundamentals of ASR Fundamentals of ASR ASCRS 2016 Recognize the indications and learn new techniques for anterior segment surgery Fundamentals of ASR 1 Course Objectives Fundamentals of ASR ASCRS 2016 Recognize the indications and learn new techniques for anterior segment surgery Fundamentals of ASR 2 Course Objectives Gain a better understanding of surgical options for anterior segment repair

Transcript of 1 techniques for anterior segment surgery 2 techniques for...

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Fundamentals of Anterior Segment Reconstruction

ASCRS 2016New Orleans, LA

Fundamentals of ASR ASCRS 2016

Thank You

Fundamentals of ASR

Fundamentals of ASR ASCRS 2016

• Recognize the indications and learn new techniques for anterior segment surgery

Fundamentals of ASR

1Course Objectives

Fundamentals of ASR ASCRS 2016

• Recognize the indications and learn new techniques for anterior segment surgery

Fundamentals of ASR

2Course Objectives

• Gain a better understanding of surgical options for anterior segment repair

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Fundamentals of ASR ASCRS 2016

• Understand the advantages and disadvantages of different intra-ocular capsular stability devices

Fundamentals of ASR

3Course Objectives

• Recognize the indications and learn new techniques for anterior segment surgery

• Gain a better understanding of surgical options for anterior segment repair

Fundamentals of ASR ASCRS 2016

Course Faculty

Fundamentals of ASR

W. Barry Lee, MD John Berdahl, MD Brandon Ayres, MD Jeremy Kievel, MDElizabeth Yue, MDNicole Fram, MD

Fundamentals of ASR ASCRS 2016Fundamentals of ASR

Faculty•Specializes in advanced Cataract, Corneal and Glaucoma Surgery, in addition to Refractive Surgery

•Medical school at the Mayo Clinic in Rochester, MN •Residency at Duke University •Cornea and glaucoma fellowship at Minnesota Eye Consultants•Research interests include CSF pressure in Glaucoma, Minimally Invasive Glaucoma Surgery, and Refractive Laser Assisted Cataract Surgery (ReLACS).

Sutured AO60John Berdahl, MD

ASCRS 2016Fundamentals of ASR

Faculty

Nicole Fram, MD

Residency at Wills Eye Hospital

Fellowship in Cornea and External Disease and Uveitis at Francis I. Proctor Foundation UCSF

Clinical Instructor at Jules Stein Eye Institute UCLA

Expertise in premium cataract surgery, cornea and external disease, as well as anterior segment reconstruction

Sutured IOL’s

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Fundamentals of ASR ASCRS 2016Fundamentals of ASR

Faculty

•Boston Native•Medical school and Residency in Ophthalmology at Boston University and Boston University Medical Center

•Fellowship training in Cornea, External Disease, and Refractive Surgery at Bacom Palmer Eye Institute

•Practices at Lexington Eye Associates with offices in Lexington and Concord, MA

•Interests include corneal transplantation, presbyopic correction, and complex cataract surgery

•Serves on the clinical committee for ASCRS

Jeremy Kievel, MDIOL Exchange

Fundamentals of ASR ASCRS 2016Fundamentals of ASR

Faculty

•Residency at Rush University Medical Center in Chicago, IL•Fellowship in Cornea, Anterior Segment and Refractive Surgery at Cullen Eye Institute, Baylor College of Medicine

•Assistant Professor of Ophthalmology at Cullen Eye Institute, Baylor College of Medicine

•Virginia Eye Consultants

Capsular Tension RingsElizabeth Yeu, MD

Fundamentals of ASR ASCRS 2016Fundamentals of ASR

Faculty•Board of Directors and Scientific Chair of the Cornea Society

•Medical director of the Georgia Eye bank•Partner at Eye Consultants of Atlanta•Fellowship training at University of California, Davis in Sacramento CA in Cornea, External Eye Diseases, and Refractive Surgery

The Complex CataractW. Barry Lee, MD

Fundamentals of ASR ASCRS 2016Fundamentals of ASR

Faculty

•Residency training at UMDNJ, New Jersey Medical School

•Fellowship in Cornea, External Disease, and Refractive Surgery at Wills Eye Institute, Philadelphia PA

•Cornea Service at Wills Eye Hospital, Philadelphia, PA•Private Practice at Ophthalmic Partners of Pennsylvania

Iris RepairBrandon Ayres, MD

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Sclerally  Fixated  Akreos  AO60  

John  Berdahl    

Discosures:    Alcon,  Allergan,  Bausch  &  Lomb,  Glaukos  

Akreos  AO  60  Hydrophilic  Acrylic  Very  SoF  Material  Zero  Asphericity  4  point  FixaJon  Small  Incision  No  Sharp  Edges  

1.  Parekh  P,  Green  WR,  Stark  WJ,  Akpek  EK.  SubluxaJon  of  suture-­‐fixated  posterior  chamber  intraocular  lenses  a  clinicopathologic  study.  Ophthalmology  2007;114:232–237.  

� r x� Ft � � � � Jp� J � xFi c lal� � � � xJ al� �� � xJ � � F � � �d � xl�a �� � xF � � ti c � xl� ldJ �Z� i Fl   d� � l0�A F   �� y �a a�   � ltlF   �� F � � c �x i � � � S� t �

V:� � �x � r c � � B� � x� �   � � � B� � d�x r � � � B� � r i � r � � � :� � s � as 0�A F   � F � � ts ds x� g� 0�d � � � iF td� xlFx�� c �y � � x� l   dx�F � s a�x � a�   t � t � �� � al   l� Fi �d cFaFSl� � tds � J :� � i cdc �a y FaFSJ � FppI DVVZuFMF&FMI :�

Scleral  FixaJon  Advantages  Everybody  has  a  sclera  IOL  Fixated  First  Good  Stability  with  DSEK  No  Correctopia  No  Iris  Chaffing  No  Cheesewireing  

Disadvantages  Long  Procedure  Avoid  blebs  Poor  Reimbursement  External  Sutures  could  be  cut  

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Steps  1.          Block  2.  Take  down  Conj  (6  to  8  and  12  

to  2  Surgeons  view)  3.  Cauterize  4.  Mark  suture  locaJons  4.5mm  

apart    5.  Insert  AC  maintainer  6.  Create  4mm  incision  at  5  o’clock    7.  Remove  Old  IOL  and  Vitrectomy      

8.  Thread  distal  loops  with  double  armed  CIF  9-­‐0  Prolene  for  mairess  suture  

9.  Externally  place  docking  27g  needle  through  sclera  at  suture  locaJons.  

10.  Repeat  8  &  9  at  proximal  loops  11.  Fold  and  insert  IOL  12.  Tighten  sutures  to  center  13.  Tie  and  bury  knots  14.  Close  ConjuncJva  

Thank  you  

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4/28/16

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Elizabeth Yeu, MD Virginia Eye Consultants, Norfolk, VA

Asst Professor, Eastern Virginia Medical School Norfolk, VA

Financial Interest Disclosures

�  Abbott Medical Optics: A, B �  Alcon Laboratories, Inc.: A, B �  Allergan, Inc.: A, B �  ArcScan, Inc: A, R �  Bausch & Lomb, Inc./Valeant: A �  BioTissue: A, B, R �  Eyekon E.R.D LTD: A �  iOptics: A, B, R �  Kala Pharmaceuticals: A

�  Modernizing Medicine: I �  Ocular Therapeutix: A, B �  Omeros: B �  Ocusoft: A �  RPS: B, I �  Shire: A, B �  Strathspey Crown: I �  TearLab Corporation: A �  Tear Science: A �  Topcon: R

�  Standard ring �  Sew-in Ring

�  Cionni CTR: single or double islets

�  Ring segment �  Ahmed capsular tension segments

Capsular Tension Devices

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� �  Indications

�  <3-4 clock° of zonular loss �  Mild zonular instability

�  Injector or free hand �  Should not be used in anterior

capsular tear, a discontinuous capsulorhexis, or a p-cap tear

Capsular Tension Rings

� Capsular Tension Rings

� �  Dial in TOWARDS area of

instability �  Injector �  Free hand: 2nd instrument to

alleviate stress against capsulorhexis

Capsular Tension Rings

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� �  Sutured CTR should be considered

for > 4-5 clock hours of zonular loss �  Obviously dislocated lens �  Profound zonular instability

�  Cannot use with anterior capsular tear, a discontinuous capsulorhexis, or a p-cap tear

Sew-in CTR

� Cionni CTR

Double-armed Non-Dissolvable Suture

Ethicon® Double-Armed 3” 9-0 CTC-6L (curved) or STC-6L (straight)

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� 8-0 GORE-TEX®

Ahmed Capsular Tension Segments

� Easier than sutured CTR � Ant or post capsular tear

may be okay � No-dialing technique à

min capsular/zonular trauma

� Can combine w/ CTR

� �  Mild zonulopathy can be managed with

a 3-piece IOL in the bag �  Difficulty: CTR < CTS < sew-in CTR �  Always manage vitreous prolapse

around areas zonulolysis �  If bag compromised, possible IOL

exchange +/- suture fixation

Conclusion

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1 Pearls to Prevent Peril in Complex Cataract SurgeryW. Barry Lee, M.D., F.A.C.S.Cornea ServiceEye Consultants of AtlantaMedical Director, Georgia Eye BankAtlanta, Georgia, USA

2 Financial DisclosuresAllerganShireBausch & LombMedevex Imaging SystemsBioTissue

3 When Phaco Is Not RoutineSmall PupilWhite CataractTraumatic CataractAnterior Capsule TearIntraoperative Floppy Iris Syndrome (IFIS)Fuchs Dystrophy

4 Small PupilCauses

Mature CataractPseudoexfoliationGlaucomaUveitis (Posterior Synechiae)Medications

MioticsProstaglandinsFloppy Iris Syndrome (IFIS)

5 Surgical Options Posterior Synechiolysis (Iris sweep or OVD cannula)Overfill with OVDPupil Stretching (Lester or Kuglen hooks)Iris HooksPupil Expansion Devices (Graether, Morcher, Oasys, Malyugin ring)

6 Pupil Expansion Devices7

Posterior Synechiae / Malyugin ring Insertion

Posterior Synechiae / Malyugin ring Insertion8 White Cataract / Small Pupil / IFIS9 White Cataract

ChallengesDifficulty with Anterior Capsule ViewOften associated with small pupilZonular laxity more common

Anterior capsule staining techniquesTrypan blueIndocyanine green

1011 21-Gauge to Aspirate/lower intracapsular pressure12 Traumatic Cataract13 Traumatic Cataract

Preoperative examHistoryPhacodonesis?Vitreous prolapse?Iris sphincter damage? (Poor dilation)Phaco / Extracapsular / Intracapsular technique?

141516 Anterior Capsule Tear

Concerns & ConsiderationsExtension to posterior capsulePosterior capsule rupture / Vitreous lossLens implant stabilityPlacement of lens in bag or sulcus?Lens implant (3-piece or 1-piece)?

17 Anterior Capsule Tear PearlsRefill with cohesive OVD to attempt saveCan reverse direction of capsulorrhexisCanopener capsulorrhexis can help if lost peripherallyOnly gentle hydrodelineation

18 Reverse the rhexis to rescue ant. tear19 Anterior Capsule Tear Pearls20 Intraoperative Floppy Iris Syndrome (IFIS)21 IFIS- Preoperative Tips

Not Helpfu

21 IFIS- Preoperative TipsNot HelpfuPre-operative topical atropine Discontinuation of alpha-blockers

22 Surgery Pearls for IFISWell-constructed incision

TriplanarLengthen tunnel

Lower fluidicsGentle HydrodissectionLower bottle for phacoIrrigation/aspiration

2324 Fuchs Dystrophy (FECD)

Hereditary endothelial dystrophyInternational Committee for Classification of Corneal Dystrophies(1) COL8A2 gene, SLC4A11 gene (2)

Onset (4th - 5th decades)Premature aging of endothelium

Guttae develop centrally and extend peripherallyEpithelial and stromal edemaUltimate haze and vascularization

25 High Power View of Endothelium26 Keys to Success

Appropriate patient selection & surgical decision makingAlteration of incision siteUse of protective ophthalmic viscosurgical devices (OVD’s)Limit fluid irrigation timeLimit nucleus removal timePostoperative medication regimen (Longer steroid use)

27 Refractive Outcomes of DSAEK28 IOL Opacification

Has been described in eyes following DSAEK after cataract surgeryOccurs with Hydrophilic acrylic lenses Hydroxyapatite deposition on IOL surface Often requires IOL exchange

29 ConclusionsEvery cataract surgery is differentBe prepared for special situations that add complexity to cataract surgery

Every cataract surgery is differentBe prepared for special situations that add complexity to cataract surgeryFamiliarize yourself with the different devices to improve cataract surgical skill and efficiency in challenging casesDifficult cases can be made routine when adjunct devices are mastered

30 Ernst Fuchs (1851-1930)

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Jeremy Z. Kieval, MDCornea, Cataract, and Refractive Surgery

Lexington Eye AssociatesLexington, MA

American Society of Cataract and Refractive Surgery2016 Annual Meeting

FinancialDisclosures� Alcon, speaker� Abbott Medical Optics, consultant/speaker� Shire, consultant/speaker

IndicationsforIOLexchange� Refractive error

� Anisometropia� Refractive surprises/post excimer laser vision correction� Toric errors

� Visual symptoms� Positive dysphotopsia� Negative dysphotopsia� Inadequate visual function

� Malpositioned IOL� Zonulopathy– PXF, trauma, uveitis, RP, long AL� Iatrogenic causes� Therapeutic indication

� UGH syndrome� IOL deposits

� Calcifications� ?Glistenings

Prepareforsurgery!� Know the history� Slit lamp exam:

� Capsule/capsulotomy status� Zonular status� Endothelial cell status� Incision locations/astigmatism� IOL type� Position of the haptics

� Exchange vs. Reposition� Pars plana vs. limbal approach� Pt expectations, CME, capsular compromise, open capsules

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Surgicalprocedure� Retro/peribulbar block � Instrumentation

� Viscoelastics� Viscodisection : 27g needle vs cannula vs. bimanual� Iris hooks� Capsular retractors� Lens manipulators� Microsurgical forceps and scissors� Vitrector� Triesence®� Suture

Outwiththeold…� Removing the IOL from the bag

� Entirely� Amputate haptics

� Removing the IOL from the eye� Cut� Fold� Dial� Pull

Inwiththenew…� Where to put it:

� In the bag� In the sulcus� Optic capture� ACIOL

� Inject new IOL before taking out old� Iris fixation

� McCannell suture� Seipser knot

� Scleral fixation

Iris RepairBrandon D. Ayres, MD

ASCRS 2015SanDiego, CA

Financial Disclosure• Alcon

• Allergan

• Bausch and Lomb

• Bio-Tissue

• Micro Surgical Technology

• Rapid Pathogen Screening

• Omeros

• ShireBrandon D. Ayres, MDCornea Service WEH

Why Repair the Iris• Not all iris defects need repair

• Small traumatic iris defects

• Peripheral iridotomy

• Iris capture after large incision cataract surgery

• Symptomatic iris defects need repair

• To assist with another anterior segment procedure

• Cosmesis

Brandon D. Ayres, MDCornea Service WEH

Major Categories

• Iridodialysis (usually from trauma)

• Sphincter tears leading to irregular pupil

• Loss of tissue from trauma

• Atonic pupil

• Aniridia

Brandon D. Ayres, MDCornea Service WEH

Iridodialysis• Commonly seen in ocular trauma

• Can be surgically induced

• Watch for zonular loss in are of dialysis, makes cataract surgery more challenging

• Timing is important

• Wait long enough for inflammation to clear

• Waiting too long may make the repair very difficult

Brandon D. Ayres, MDCornea Service WEH

Technique• Needle: CIF-4 or

STC-6 10-O prolene• Needles enter through

small incision• Use guide needle

through sclera or pocket

• Tie sutures after all mattress sutures placed

Brandon D. Ayres, MDCornea Service WEH

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Brandon D. Ayres, MDCornea Service WEIBrandon D. Ayres, MDCornea Service WEI

Brandon D. Ayres, MDCornea Service WEI

Technique

Brandon D. Ayres, MDCornea Service WEI

Technique Technique

64 Year old woman s/p shovel injury to eye leaving her with corneal scar, aphakia, and with iridodialysis

Iridodialysis Repair Open Sky

Brandon D. Ayres, MDCornea Service WEH

Iris Tears or Loss of Tissue

• Often due to floppy iris and phaco or IA tip grabbing the iris or trauma

• Often seen in the setting of trauma

• Defects can be asymptomatic or allow edge glare

• May be cosmetically unappealing in light colored eyes

Brandon D. Ayres, MDCornea Service WEH

Technique

• Needle: Curved needle (CIF-4)10-O prolene

• Needles enter through small incision

• No exit incision is needed

• Tie knot using a sliding knot technique

Brandon D. Ayres, MDCornea Service WEH

Tech

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Brandon D. Ayres, MDCornea Service WEHBrandon D. Ayres, MDCornea Service WEH

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Brandon D. Ayres, MDCornea Service WEHBrandon D. Ayres, MDCornea Service WEH

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Brandon D. Ayres, MDCornea Service WEHBrandon D. Ayres, MDCornea Service WEH

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Atonic Pupil

• Large dilated pupil can be difficult to close

• Large pupil can cause glare in phakic and pseudophakic patients

• Can be helpful to use prosthetic contact lens to see if symptoms resolve prior to surgical intervention

Brandon D. Ayres, MDCornea Service WEH

Atonic Pupil• Idiopathic

• Orbital trauma

• Herpes Zoster Infection

• Diabetes

• Autonomic neuropahties (Riley Day)

• Guillain Barre syndrome

• Narrow angle glaucoma

Etiology

Brandon D. Ayres, MDCornea Service WEH

Technique• 4 Paracentesis necessary

• Carefully pass suture through pupil border in baseball style

• Exit through paracentesis using a cannula so you don’t grab fibril of cornea

• After 4th pass tie knot and adjust size

Brandon D. Ayres, MDCornea Service WEH

Fixate IOLUnder-over fixation

Adjust sutures

Cerclage4 points/pass

Use cannula at exitpoints

Adjust suture tension in the AC

Brandon D. Ayres, MDCornea Service WEH

Aniridia

Brandon D. Ayres, MDCornea Service WEH

Aniridia• Traumatic: Penetrating trauma or surgical

trauma

• Congenital

• 2/3 familial and 1/3 sporadic

• Autosomal dominant, from mutation in PAX6 gene on chromosome 11

• May be associated with WAGR syndrome

Brandon D. Ayres, MDCornea Service WEH

Aniridia

• Other less common causes

• ICE Syndrome

• Reiger’s anomaly and other anterior segment dysgeneses

• HSV and HZV

Brandon D. Ayres, MDCornea Service WEH

Available Devices

Brandon D. Ayres, MDCornea Service WEH

• Multiple types of iris prosthesis

• Modified CTR

• Ophtec

• Morcher aniridic IOL

• Dr. Schmidt/Human Optics silicone artificial iris

Brandon D. Ayres, MDCornea Service WEH

Color Match Systems

OphtecMorcherDr. Schmidt AI

Available Devices

Brandon D. Ayres, MDCornea Service WEH

There is currently no FDA approved iris prosthesis device

The Dr. Schmidt/HumanOptics Artificial Iris is currently under US FDA clinical trials to evaluate safety and efficacy, and is

available for compassionate use under the clinical trial.

Available Devices Surgical Management

Brandon D. Ayres, MDCornea Service WEH

Surgical Management

Brandon D. Ayres, MDCornea Service WEH

Aniridia

Brandon D. Ayres, MDCornea Service WEH

Aniridia

Brandon D. Ayres, MDCornea Service WEH

Brandon D. Ayres, MDCornea Service WEIBrandon D. Ayres, MDCornea Service WEI

Brandon D. Ayres, MDCornea Service WEIBrandon D. Ayres, MDCornea Service WEI

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Summary

Brandon D. Ayres, MDCornea Service WEH

• Iris repair can be very rewarding for both physical and patient

• Multiple techniques may need to be used for successful repair

• In cases where repair is not possible, prosthetic devices may be available in future to help alleviate patient symptoms and enhance cosmesis

Thank YouBrandon D. Ayres

[email protected]