NATIONAL UNIVERSITY OF PHARMACY Department of Clinical Laboratory Diagnostic

ПіуріяПіурія

More than 60 in sight

E. coli in urine (different

multiplicity enlarge)

The crystals of uric acid

Urate crystals

Crystals of tripelphosfats

Amorphous phosphate crystals

Crystals urine acid ammonium

Crystals phosphate of lime

Oxalate crystals

Crystals of cholesterol and bilirubin

Characteristics of the glomerular filtration rate

Normally, men - 120 ± 25 ml / min, for women - 95 ± 20 ml / min

In violation of the outflow of urine appears fever, symptoms of intoxication, leukocytosis, leukocyte shift to

the left, increasing SHOЭ and anuria

«... The problem of the safety and efficacy of medicinal products is becoming increasingly

important worldwide. This is due to the introduction of the medical practice of a large number of pharmacological agents, irrational

use of medicines, medical errors ... »

World Health Organization, 2006

Humanitarian disasters related to drugs:1937 - Mr. sulfanilamide in diyetylenhlykoli1961 - thalidomide1983 - zomepyrak1983 - osmozyn1982 - benoksaprofen2001 - tseryvastatyn2005 - problem koksybiv2006 - problem antidepressants

Nephrotoxicity drugs or "drug nephropathy" - direct or indirect

(via the immune response) poshkodzhuyacha effect of drugs on urinary system and, above all,

on tubular and glomerular apparatus

Nephrotoxicity drugs or "drug nephropathy" - direct or indirect

(via the immune response) poshkodzhuyacha effect of drugs on urinary system and, above all,

on tubular and glomerular apparatus