ThinkAirbnb

PhilipE.Bourne,PhD,FACMITheNationalInstitutesofHealth

http://www.slideshare.net/pebournephilip.bourne@nh.gov

Bonazzi &Bourne2017,PLOSBiology,InPress

TheStateofPlayforNGSandBeyond

• Dataandanalyticsaresiloed• Dataarecomplexandbeinggeneratedatexponentialrates(?)• Computemustmovetothedata• ThinkingFAIRisdifferentfrombeingFAIR• Currentpracticesareinefficient• Reproducibilityismythical(perhapsevenwiththerighttools)• Incentivestodobetterareminimalbutgrowing

ExamplesfrommyOwnWork

Ittookseveralmonthstoreplicatethisworkthiswork

…Andjustlastweek…

Phew…

http://www.sdsc.edu/pb/kinases/

ToolsFixThisProblemRight?

• ExtractedallPMCpaperswithassociatedJupyter notebooksavailable• Approx 100• Tookarandomsampleof25• Only1ranoutofthebox• Severalranwithminormodification• Otherslackedlibraries,sufficientdetailstorunetc.

Ittakesmorethantools..Ittakesincentives…

DanielMietchen2017PersonalCommunication

Iamnotcrazy,hearmeout

• Airbnbisaplatformthatsupportsatrusted relationshipbetweenconsumer(renter)andsupplier(host)• Theplatformfocusesonmaximizingtheexchangeofservicesbetweensupplierandconsumerandmaximizingtheamountoftrustassociatedwithagivenstakeholder• Itseemstobeworking:• 60millionuserssearching2millionlistingsin192countries• Averageof500,000stayspernight.• EvaluationofUS$25bn

Isnotbiomedicalresearchthesame?

WhyacomparisontoAirbnbisnotfair

•Airbnbwasborndigital

• TheexchangeofservicesonAirbnbaresimplecomparedtowhatisrequiredofaplatformtosupportbiomedicalresearch

Neverthelessthereismuchtobelearnt

PaperAuthor PaperReader

DataProvider DataConsumer

Employer Employee

ReagentProvider ReagentConsumer

SoftwareProvider SoftwareConsumer

GrantWriter GrantReviewer

Supplier Consumer Platform

MSProjectGoogleDriveCoursera

ResearchgateAcademia.eduOpenScienceFrameworkSynapseF1000Rio

Educator Student

Platforms- TheSituationToday

Insummarythereisnotcurrentlyawidelyadoptedsingleplatformfortheexchangeofservicesinbiomedicalresearch.Eitherthereisaplatformperserviceornoplatformatall. Whyhavewenotdonebetterandwhataretheimpedimentstoday?

Impedimentstoabiomedicalplatform

•Currentworkpracticesbyallstakeholders• Entrenchedbusinessmodels• Sizeoftheundertakingakaresourcesneeded• Trust• Incentivestousetheplatform

http://www.forbes.com/sites/johnhall/2013/04/29/10-barriers-to-employee-innovation/#8bdbaa811133

TheNIHthroughtheBigDatatoKnowledge(BD2K)andothersareexperimentingwithaplatform,keepinginmindtheneedtoovercometheseimpediments

EnterTheCommons

https://en.wikipedia.org/wiki/Ealing_Common#/media/File:Ealing_Common_-_geograph.org.uk_-_17075.jpg

PaperAuthor PaperReader

DataProvider DataConsumer

Employer Employee

ReagentProvider ReagentConsumer

SoftwareProvider SoftwareConsumer

GrantWriter GrantReviewer

Supplier Consumer Platform

MSProjectGoogleDriveCoursera

ResearchgateAcademia.eduOpenScienceFrameworkSynapseF1000Rio

Educator Student

Commons–Initialfocusisonintegratingtwolayersofthescholarlyworkflow

CommonsTopology

ComputePlatform:CloudorHPC

Services:APIs,Containers,Indexing,

Software:Services&Tools

scientificanalysistools/workflows

Data“Reference”DataSetsUserdefineddata

DigitalObjectCom

pliance

Appstore/UserInterface

PaaS

SaaS

IaaS

https://datascience.nih.gov/commons

“IreallyadmireAirbnbasapioneerofthesharingeconomyandforbuildingcommunity.They'vefoundanelegantwaytohelphostsmakemoremoneyandforgueststohaveauthenticexperiences.Itbringsthosepeopletogetherinauniqueway.“

LoganGreen

“TheCommonsisoneeffortatcreatingasharingeconomyandforbuildingcommunity.Wehopeforamorecosteffectiveandproductiveresearchenvironmentwhilebringingpeopletogetherinauniqueway.“

PhilBourne

Acknowledgements

• VivienBonazzi,JennieLarkin,MichelleDunn,MarkGuyer,AllenDearry,Sonynka Ngosso,TonyaScott,LisaDunneback,Vivek Navale (CIT/ADDS)

• NLM/NCBI:MikeHuerta,GeorgeKomatsoulis• NHGRI:Valentina diFrancesco

• NIGMS:SusanGregurick

• CIT: DebbieSinmao,AndreaNorris

• NIHCommonFund:JimAnderson,BetsyWilder,LeslieDerr

• NCICloudPilots/GDC:WarrenKibbe,TonyKerlavage,Tanja Davidsen

• CommonsReferenceDataSetWorkingGroup:Weiniu Gan (HL),AjayPillai(HG),ElaineAyres,(BITRIS),SeanDavis(NCI),VinayPai (NIBIB),MariaGiovanni(AI),LeslieDerr (CF),ClaireSchulkey (AI)

• RIWGCoreTeam:RonMargolis(DK),IanFore,(NCI),AlisonYao(AI),ClaireSchulkey (AI),EricChoi(AI)

• OSP: DinaPaltoo,KrisLanglais,ErinLuetkemeier,AgnesRooke,

Bonazzi &Bourne2017,PLOSBiology,InPress