ADRENAL GLANDADRENAL GLAND

PAIRED.PAIRED.

PRESENT ON KIDNEYSPRESENT ON KIDNEYS

3-5 cm, 3.5-5 gm.3-5 cm, 3.5-5 gm.

COMPLETE LOSS OF ADRENAL COMPLETE LOSS OF ADRENAL GLANDS LEADS TO DEATHGLANDS LEADS TO DEATH

UNTIL THE REPLACEMENT THERAPY UNTIL THE REPLACEMENT THERAPY BEGINSBEGINS

TWO TWO REGIONSREGIONS

ADRENAL

CORTEX

ADRENAL MEDULLA

ADRENAL CORTEX

ZONA GLOMERULOSA

ZONA FASCICU

LATA

ZONA RETICULARIS

ADRENAL MEDULLAADRENAL MEDULLA

NOT ESSENTIAL FOR LIFENOT ESSENTIAL FOR LIFE

FOR PERSON COPING WITH FOR PERSON COPING WITH PHYSICAL AND EMOTIONAL PHYSICAL AND EMOTIONAL STRESSSTRESS

PROCESS OF RELEASING PROCESS OF RELEASING HARMONESHARMONES

HYPOTHALAMUS HYPOTHALAMUS

CARTICOTROPIN RELEASING CARTICOTROPIN RELEASING HARMONE HARMONE

PITUITARY GLANDSPITUITARY GLANDS

CARTICOTROPIN CARTICOTROPIN HARMONESHARMONES

ADRENAL GALNDADRENAL GALND

CORTICOSTEROID HARMONESCORTICOSTEROID HARMONES

THREE HARMONESTHREE HARMONES

MINERALOMINERALOCORTICOICORTICOI

DSDS

GLUCOCGLUCOCORTICOIORTICOIDSDS

ANDROANDROGENSGENS

ADRENAL MEDULLAADRENAL MEDULLA

CHROMAFFINCHROMAFFIN CELLS CELLS

EPINEPHRINE NOR EPINEPHRINE

DISORDERS • CUSHINGS SYNDROME

• ADDISON’S SYNDROME

• PHEOCHROMOCYTOMAS

CUSHINGS SYNDROMECUSHINGS SYNDROME HYPER SECRETIONHYPER SECRETION

BREAK DOWN OF PROTEINSBREAK DOWN OF PROTEINS

MOON FACEMOON FACE

BUFFALO HUMPBUFFALO HUMP

WOUND HEALING IS POORWOUND HEALING IS POOR

CUSHINGS

SYNDROME

ADDISON’S DISEASE

HYPO SECRETION

VOMITING

WEIGHT LOSS

CARDIAC OUTPUT

PHEOCHROMOCYTOMAS

• TUMOURS OF CHROMAFFIN CELLS• HYPER SECRETION OF EPINEPHRINE

AND NOR EPINEPHRINE• RAPID HEART RATE• HIGH B.P• LOSS OF GLUCOSE IN URINE• SWEATING

THANK U VERY MUCH

K BHARATH REDDY