Pulmonary Hypertension In Developing World

An Overview

Schistosomiasis10-20 M

High altitude5-7 M

Others

HIV

PHT in the Developing

World15-30 MPHT

in the developed world

0.5- 1 M

Pulmonary Hypertension in the world

Pulmonary Hypertension Associated with:

• Schistosomiasis • HIV • Congenital Heart Disease • Rheumatic valvular diseases • Chagas disease• Endomyocardial Fibrosis• High Altitude• Haemolytic anemia

Severe PHT due to Schistosomiasis

Courtesy of Dr. Ângela Pontes Bandeira

High altitude associated pulmonary hypertension

• More than 140 million people worldwide live >2500 m above sea level. – 80 M in Asia,– 35 M Andean mountains

• Genetic predisposition

• Other environmental factors

HIV associated pulmonary hypertension

• The prevalence is 0.5%• In Africa suggested that the prevalence

may range from 0.6% to 5%, – with higher numbers in the hospitalized as

opposed to ambulant patients

• The incidence however has not been affected by the introduction of the HAART treatment

Cardiac conditions associated pulmonary hypertension

• Cardiac pathology in the developing world may differ– Congenital heart diseases treated late– Pattern of the pathology may differ– Rheumatic fever and Rh.H.D.– Endomyocardial fibrosis– Chagas diseases

PVRI in Latin AmericaPVRI in Latin America

PVRI in China