PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany.

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Transcript of PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany.

PDT IN DERMATOLOGYRolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

PDT IN DERMATOLOGY•First use in this speciality in the early 1900• surface illumination• variety of indications (cancer, infection)

PDT IN DERMATOLOGY• registered drugs since the late 90ies• 5-ALA (solution, gel, patch) (for AK)• 5-ALA methyl ester (ointment) for AK, init. SCC, nod. & superf. BCC

• no restrictions for illumination (lasers, LED, lamps, sunlight)

• excellent data• high clearance rates• favorable cosmetical results

WHY ISN‘T PDT A KILLER APP?

• light / drug combination – procedure – learning

curve

• side effects esp. pain

• reimbursement issues

WHY ISN‘T PDT A KILLER APP?

• light / drug combination – procedure – learning

curve

• side effects esp. pain

• reimbursement issues

passed

WHY ISN‘T PDT A KILLER APP?

• light / drug combination – procedure – learning

curve

• side effects esp. pain

• reimbursement issues

passed

passed

WHY ISN‘T PDT A KILLER APP?

• light / drug combination – procedure – learning

curve

• side effects esp. pain

• reimbursement issues

passed

passed

can this ever be solved?

EMERGING & NEW INDICATIONS

• „classical“ NMSC-PDT

GROWING INCIDENCE OF NON-MELANOMA SKIN CANCER

© DermatologyWorld 3-15

EMERGING & NEW INDICATIONS

• „classical“ NMSC-PDT

• PDT and aesthetic medicine

• combinatoric approaches

• PDT and microbioma/colonization

• eczema, psoriasis & pilosebaceous disorders