DNA DNA STRUCTURESTRUCTURE

Where is DNA located?Where is DNA located?

Prokaryotic vs EukaryoticProkaryotic vs Eukaryotic

Johann FreidrichJohann Freidrich

MeisherMeisher1869

Isolated the first crude extract of DNA from white blood cells.

He called it nuclein.

Rosalind Rosalind Franklin & Franklin & Maurice Maurice WilkensWilkens1952

Used X-ray diffraction to understand the

physical structure of the DNA molecule

James James Watson & Watson & FrancisFrancis Crick Crick

1953

Formulated the correct double-helix

structure of the DNA molecule.

Double HelixDouble HelixIs the shape of the DNA molecule that looks like “twisted ladder structure.”

Made up of a backbone & complementary bases

BackboneBackboneMade up of sugar & phosphate molecules.

Complementary bases Complementary bases fit together based on fit together based on

shape.shape.

Thymine = Adenine

Cytosine = Guanine

NucleotideNucleotideMade up of one phosphate, one sugar, one nitrogen base

What macromolecule is made What macromolecule is made when nucleotides are put when nucleotides are put

together??together??

DNADNADNA is a nucleic acid!

Which one is human?Which one is human?

Which one is human?Which one is human?

All All living things have the same DNA living things have the same DNA STRUCTURE! STRUCTURE! (all DNA is made up of (all DNA is made up of

phosphates, sugar, & bases)phosphates, sugar, & bases)

Genetic Code depends on order of the Genetic Code depends on order of the bases.bases.

DNA > ChromosomesDNA > Chromosomes

DNA is wound up very tightly in the form of a chromosome. Chromosomes are located in the nucleus of the cell.

PRACTICE…..PRACTICE…..If one strand of DNA has the base sequence CCGATT, the bases on the other strand of DNA are: _________________________________

If one strand of DNA has the base sequence TAAGGCGATGC, the bases on the other strand of DNA are: _________________________________