Development & anomalies respiratory system embryology

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Transcript of Development & anomalies respiratory system embryology

Respiratory systemDevelopment & anomalies

Maj Rishi Pokhrel, MDAnatomy

NAIHSwww.slideshare.net

What triggers labor of childbirth?

Respiratory diverticulum

25 Day embryo

Partition of tubes

Larynx

6 week 12 week

4th arch: superior laryngeal N 6th arch: superior laryngeal N

Trachea, bronchi & lungs

Prenatal: 17 generationsPostnatal: 6 generations

• Epithelium: endoderm• Cartilage, muscles, connective tissue:

mesoderm

Pleural cavity

Maturation of lungs

DEVELOPMENT OF DIAPHRAGM

Defects in partition of foregutesophageal atresia / Tracheo-esophagal fistula

Total Incidence: 1/3000

90%4%4%

1% 1%

VACTERAL association

• V: Vertebral anomalies• A: Anal atresia• C: cardiac defects• E: esophageal atresia• R: renal anomalies• L: limb defects

• Respiratory distress syndrome / hyaline membrane disease

• Ectopic lung lobes• Congenital cysts of lungs

Assignment

• Poly-hydraminos?• Oligo-hydraminos?