DBW Project

DiseaseOMICS

Brasó M., Carlevaro J., Perera J. and Rubio C.

DiseaseOMICSAbout

Disease

Genes

Metabolicpathways

Biologicalprocess

Molecularfunctions

DiseaseOMICSAbout

Schizophrenia

Genes

Metabolicpathways

Biologicalprocess

Molecularfunctions

DiseaseOMICSAbout

Schizophrenia

Genes

Metabolicpathways

Biologicalprocess

Molecularfunctions

Cancer

Genes

Metabolicpathways

Biologicalprocess

Molecularfunctions

Increase basic reasearch knwoledge on diseases

Better comprehension of comorbid conditions

Polypharmacy avoidance

DiseaseOMICSAbout

Schizophrenia Cancer

Genes

Metabolicpathways

Biologicalprocess

Molecularfunctions

Genes

Metabolicpathways

Biologicalprocess

Molecularfunctions

Rubio-Pérez C, Guney E, Piñero J, Furlong LI and Oliva B.Investing disease comorbidityvia protein interaction networks using gene prioritization algorithms.

DiseaseOMICSDatabase

Starting with the rough data of the mentioned study

DiseaseOMICSDatabase

Starting with the rough data of the mentioned study

DiseaseOMICSDatabaseDISEASES DISEASE PAIRS

Disease 1123 159 10 334

MeSH ID GUILD(score) GUILD(score) GUILD(score) GUILD(score)

mesh:D000230 1 3.2 0 0

mesh:D000236 2.32 10.3 5.2 1

mesh:D003324 1 6.1 1 0

Disease Genes

Disease GO terms

Disease GO:001213 GO:100234 GO:031223 GO:232321

MeSH ID P-value P-value P-value P-value

mesh:D000230 1.3434e-1 3.2211e-12 1 1

mesh:D000236 1 1 1 1.1111e-10

mesh:D003324 1 6.1233e-15 1 1

Disease Pathways

Disease REACT_2223 REACT_1102 REACT_1234 REACT_1111

MeSH ID P-value P-value P-value P-value

mesh:D000230 1 1 1 1.3434e-1

mesh:D000236 1 3.2211e-12 1 1.1111e-10

mesh:D003324 1.2222e-5 1 6.1233e-15 1

ID_pair Disease 1 Disease 2 1123 159 10

Num MeSH ID MeSH ID GUILD(score) GUILD(score) GUILD(score)

1 mesh:D000230 mesh:D000236 1 3.2 0

2 mesh:D000236 mesh:D007918 2.32 10.3 5.2

3 mesh:D003324 mesh:D000230 1 6.1 1

DiseaseOMICSDatabaseDISEASES DISEASES PAIRS

Disease Pairs Genes

Disease Pairs GO terms

Disease Pairs Pathways

ID pair Disease 1 Disease 2 GO:001213 GO:100234 GO:031223

Num MeSH ID MeSH ID P-value P-value P-value

1 mesh:D000230 mesh:D000230 1.3434e-1 3.2211e-12 1

2 mesh:D000236 mesh:D000236 1 1 1

3 mesh:D003324 mesh:D003324 1 6.1233e-15 1

ID pair Disease 1 Disease REACT_2223 REACT_1102 REACT_1234

Num MeSH ID MeSH ID P-value P-value P-value

1 mesh:D000230 mesh:D000230 1 1 1

2 mesh:D000236 mesh:D000236 1 3.2211e-12 1

3 mesh:D003324 mesh:D003324 1.2222e-5 1 6.1233e-15

DiseaseOMICSWeb Application

WEB TOOLS

Home (with background)

About (information of the web application)

Search (with Advanced Search)

Browser

Contact us

FAQs

Download (database)

…

Advanced search

Disease DiseaseComorbidityrelation

Genes

DiseaseOMICSWeb Application

SEARCH

Advanced search

Disease DiseaseComorbidityrelation

Genes

DiseaseOMICSWeb Application

Search shared information of a set of genes

Combine input information from different categories to the search

Select content of the search results

…

SEARCH

DiseaseOMICSObjectives

Providing integrative and useful disease information to the user ina quick and easy way

Integrate and condense knowledge related to disease associationwith other diseases through biological processes, molecularfunctions and metabolic pathways

Encourage researchers to use this application to optimize their job

Facilitate comorbidity biomedical research and drug development