Post on 16-Jul-2020
Course Specification
1-Basic Information
Title: Advanced biological pharmacy Code: DP-IP 061
Level: Diploma of Pharmaceutical Technology Department: Pharmaceutics
Unit: 3
Lecture: Two hours per week Tutorial: Practical: 1 hours Total: 3 hr/week
2- Aims of Course
This course aims to:
1- Help students to identify the factors that help on the bioavailability of the drug in
the body and the factors which help the absorption of drug into the blood.
2- Give the student knowledge on the application of the pharmacokinetic of the drug
within the body and calculate the rate of absorption and the rate of elimination of the
drug, as well as the half-life of the drug.
3- Intended Learning Outcomes of Course (ILOs):
a- Knowledge and Understanding:
By the end of the diploma, the students will be able to:
al- Be aware of the basic pharmacokinetic parameters of the drug.
a2- List factors that affects the pharmacokinetic parameters of the drug such as
rate of absorption, volume of distribution as well as rate of elimination.
a3- Be aware of other factors that affect the bioavailability of drug in the body
such as condition of the patient and age.
b- Intellectual Skills:
By the end of the diploma, the students will be able to:
b1- Identify the factors that affect the absorption of the drug from the body.
b2- Analyze the mechanism of absorption of the drug from the gastrointestinal
tract.
b3- Evaluate biological factors that affect the bioavailability of the drug.
Assiut University
Faculty of Pharmacy
2
c- Professional and practical Skills:
By the end of the diploma, the students will be able to:
c1- Calculate the area under the curve..
c2- Calculate the absolute bioavailability.
c3- Calculate the relative bioavailability.
c4- Determine the factors affecting the drug bound to plasma proteins.
d- General and Transferable Skills:
By the end of the diploma, the students will be able to:
d1- Write a detailed report on the factors that affect the bioavailability of the
drug.
d2- Use information technology in the field of drug bioavailability.
d3- Improve his knowledge continuously through self learning.
Course Contents
Topic No. of hours Lecture Tutorial / Practical
Introduction 2
Factors affecting drug
absorption
A - physical factors
B - biological agents
8
8
Pharmacokinetic absorption
of the drug
8
Methods of drug absorption 8
Drug elimination 8
Plasma proteins binding 8
Total 50
4- Teaching and Learning Methods
4.1- Lecturers
4.2- Discussions
4.3- Seminars
4.4- Reports
5- Teaching and learning methods for disables 1- Allocation of additional time to explain what is not understandable to those
students.
2 - Providing specialized places for these students
6- Student Assessment
a- Student Assessment methods
6.1- Final written exam to assess knowledge and understanding
6.2- Oral exam to assess knowledge and intellectual skills
3
b- Student Assessment Schedule
No. Assessment week
1. Final written exam In November
2.
3.
4.
c- Weighting of Assessments
No. Exam. Mark %
1. Mid-Term Examination - -
2. Final-Term Examination 50 50%
3. Oral Examination 20 20%
4. Practical Examination 30 30%
5. Semester Work - -
6- Other types of assessment - -
Total 100 100%
7- List of References
a- Course Notes ………………………………………………
b- Essential Books (Text Books) Applied Biopharmaeutics and pharmacokinetics by Lion Shargel
c-Recommended Books
Textbook of Biopharmaceutics and Pharmacokinetics by Naizi
d- Periodicals, Web Sites, …. etc ………………………………………………
………………………………………………
8- Facilities Required for Teaching and Learning …………………………………………………………………………
Course Coordinator: Professor Dr. Sayed Ismail
Head of Department: Professor Dr. Frgani Abdel-Hamid
4
University Assiut
Course Title Advanced biological
pharmacy
Faculty Pharmacy
Course Cod. ......................................
Department Pharmaceutics
Matrix of the Intended Learning Outcomes (ILOs) of the Course
General and Transferable
Skills
Professional and
Practical Skills Intellectual Skills
Knowledge and
Understanding Week Topic
a1,a2,a3 1st Introduction
d1 b1, b2,b3 a1 a2,a3 2nd
- 6th
Factors affecting drug
absorption
A - Physical factors
B - Biological agents
d1,d2,d3 c1,c2,c3 b1, b2,b3 a1 a2,a3 7th
,9th
Pharmacokinetic
absorption of the drug
d1,d2,d3 b1, b2,b3 a1 a2,a3 10th
, 11th
Methods of drug
absorption
d1,d2,d3 c1,c2,c3 b1, b2,b3 a1 a2,a3 12th
, 13th
Drug elimination
d1,d2,d3 c4 a1 a2,a3 14th
, 15th
Plasma proteins binding
Course Coordinator: Professor Dr. Sayed Ismail
Head of Department: Professor Dr. Frgani Abdel-Hamid
5
Course specification
1-Basic Information Title: Advanced Industrial Pharmacy Code: DP-IP 064
Level : Deploma of Pharmaceutical Technology
Department : Industrial Pharmacy
Unit:
Lecture: 3 hours/week Practical: 6 hours/week Total: 9hours/week
2-Aims of Course Aims of Course: are to provide the students with basic as well as
applied knowledge in the field of pharmaceutical technology.
3-Intended Learning Outcomes (ILO's)
a- Knowwledge and understanding a1- Basic knowledge about some advanced industrial pharmaceutical
topics.
a2- Regulatory information.
b- Intellectual skills: b1- Formulation design in some novel drug delivery systems.
b2- Problem solving.
c- Professional and practical skills:
c1- Instrumentation of tablet machine.
c2- Sterile area design in pharmaceutical industry.
d- General and transferable skills:
d1- Scale-up and technology transfer in tablet production.
d2- Basics of total quality assurance in pharmaceutical imanufacturing.
Assiut University
Faculty of Pharmacy
Quality Assurance Unit
Ind. Pharmacy Dept. Course Specification
6
4-Course contents:
Hours Subjects
Lecture Practical
Material of constructions and Corrosion. 9 18
Sterile Area 9 18
Sustained release 9 18
Liposomes 9 18
Transdermal delivery system 9 18
Total quality Assurance 9 18
International standard operation (ISO) 9 18
Validation 9 18
Instrumentation of tablet machine 9 18
Scale-up technology – 9 18
5-Teaching and learning methods: 1- Lectures using data show
2- Group discussion
3- Practical sessions
Teaching and learning methods for disables)
6-Student assessment (Student assessment methods): 1- Final exam
2- Practical exam
3- Oral exam
7-Assessment schedule
No. Exam Week
1 Final Exam End year
2 Oral Exam End year
3 Practical Exam During year
-Weighing of assessments:
Exam Degree %
Midterm exam 5 3.3
Final exam 75 50
Oral exam 25 16.7
Practical exam 45 30
Total 150 100
8-List of references:
a-Course notes (the department note book)
7
b-Essential books, (Text books) e.g. Pharmaceutical dosage
forms,tablets, vol 1,2,3 1996. Pharmaceutics, the science of
dosage formd design, M.Aulton
c-Recommended books, e.g. Pharmaceutical
encyclopedia, Remington pharmaceutical sciences.
d-Periodicals, Web sites……etc)
9-Facilities required for teaching and learning
a-Power poit
b-Over head projector
Course Coordinator: Prof. Dr. Ahmed Abutaleb,Prof.Dr. Ali
Abdel-Zaher, Prof. Dr. Eman Samy and Prof. Dr. Mahrous
Osman Ahmed Head of Department: Prof. Dr. Sayed Ibrahim Abdel-Rahman
8
Course Specification
1-Basic Information
Title: Advanced Physical Pharmacy Code: DP-IP 062
Level: Diploma of Pharmaceutical Technology
Department: Industrial Pharmacy
Unit:
Lecture: Two hours per week Tutorial: Practical: 4 hours Total: 6 hr/week
2- Aims of Course
This course aims to help students to know:
1- Different methods used in solubilizing drugs and their equations.
2- Methods of diffusion of drugs.
3- Drug stability and calculation of expiration date.
3- Intended Learning Outcomes of Course (ILOs)
a- Knowledge and Understanding:
By the end of the diploma, the students will be able to:
al- Be aware of the basics mechanisms of diffusion of drug from gels.
a2- Describe the mechanism of release of drugs from pharmaceutical preparations.
a3- Illustrate the rate of drug degradation in the pharmaceutical preparation.
a4- Be aware of the interactions between drugs and excipient.
b- Intellectual Skills:
By the end of the diploma, the students will be able to:
b1- Improve the rate of solubilization of some drugs.
b2- Increase the stability of the drug at room temperature
b3- Calculate the half-life of drugs.
b4- Calculate the expiration date of drugs
Course Specification
Assiut University
Faculty of Pharmacy
9
c- Professional and practical Skills:
By the end of the diploma, the students will be able to:
c1- Contribute in solving the problems of drugs, such as, the rate of
solubilzation, diffusion, and stability.
c2- Suggest the best ways to store the drug.
d- General and Transferable Skills:
By the end of the diploma, the students will be able to:
d1- Communicate with the research team in the pharmaceutical companies to
design the best formulation of the drug.
d2- Use a variety of scientific sources such as journals and the Internet.
d3- Ability to solve the problems of drug stability
Course Contents
Topic No. of hours Lecture Tutorial / Practical
Introduction 2 2
Types of drug degradations
a- Physical
b- Chemical
10 6
Expiration date 5 2
Applications and problems 3 2
Principals of drug diffusion 10 2
Drug release 10 2
Drug interactions 10 2
Applications 10 2
Total 60 20
4- Teaching and Learning Methods
4.1- Lecturers
4.2- Practical studies
4.3- Reports
4.4- Seminars
5- Teaching and learning methods for disables
1- Allocation of additional time to explain what is not understandable to those
students.
2 - Providing specialized places for these students
6- Student Assessment
a- Student Assessment methods 6.1- Written exam to assess knowledge and understanding
6.2- Practical exam to assess professional and practical Skills
6.3- Oral exam to assess knowledge and intellectual Skills
10
c- Student Assessment Schedule
No. Assessment week
1. Final exam In November
2.
3.
4.
c- Weighting of Assessments
No. Exam. Mark %
1. Mid-Term Examination - -
2. Final-Term Examination 50 50%
3. Oral Examination 20 20%
4. Practical Examination 30 30%
5. Semester Work - -
6- Other types of assessment - -
Total 100 100%
7- List of References
a- Course Notes ………………………………………………
b- Essential Books (Text Books) - Physical pharmacy by A-Marlin
- Remington, the science and practice of pharmacy.
c- Recommended Books - The theory and practice of industrial pharmacy Leon Lachman, Liberman and
Kanig
- Pharmaceutics, the science of dosage forms by M.E. Aulton.
d- Periodicals, Web Sites, …. etc ………………………………………………
8- Facilities Required for Teaching and Learning …………………………………………………………………………
Course Coordinator: Professor Dr. Sayed Ismail
Head of Department: Professor Dr. Frgani Abdel-Hamid
11
University Assiut
Course Title Advanced Physical
Pharmacy
Faculty Pharmacy
Course Cod. ......................................
Department Pharmaceutics
Matrix of the Intended Learning Outcomes (ILOs) of the Course
General and Transferable
Skills
Professional and
Practical Skills Intellectual Skills
Knowledge and
Understanding Week Topic
a2 1st Introduction
d1, d2,d3 c1, c2 a3 2nd
, 4th
Types of drug
degradations
a- Physical
b- Chemical
d1, d2,d3 c1, c2 b4 5th
Expiration date
d1, d2,d3 c1, c2 b2, b3,b4 6th
Applications and
problems
d1, d2,d3 a1 7th
, 9th
Principals of drug
diffusion
d1, d2,d3 c1, c2 a2 10th
, 12th
Drug release
d1, d2,d3 c1, c2 a4 13th
, 14th
Drug interactions
d1, d2,d3 c1, c2 b2, b3,b4 15th
Applications
Course Coordinator: Professor Dr. Sayed Ismail
Head of Department: Professor Dr. Frgani Abdel-Hamid
12
Course specification
1-Basic Information Title: Industrial Engineering Code: DP-IP 065
Level : Deploma of Pharmaceutical Technology
Department : Industrial Pharmacy
Unit:
Lecture: 2 hours/week Practical: 6 hours/week Total: 8hours/week
2-Aims of Course
Provide the students with the principles, concepts and theories for the unit
operating used in Pharmaceutical industry.
3-Intended Learning Outcomes (ILO's) :
a- Knowwledge and understanding al- Application of different techniques in drug industry.
a2-Understanding the basic fundamentals of various unit operations.
a3- Gaining information about the current good manufacturing practice.
b-Intellectual skills: b1- Application of mathematical knowledge.
b2- Logic thinking and rational proceeding.
c- Professional and practical skills:
cl – Understanding the basics of unit operations.
c2- Acquiring the ability of problem solving.
d-General and transferable skills:
d1-Working in a team work.
d2-Practical application of theoretical information.
Assiut University
Faculty of Pharmacy
Quality Assurance Unit
Ind. Pharmacy Dept. Course Specification
13
4-Course contents:
Hours Subject
Lectures Practical
Drying - Mixing – Particle size analysis – Size reduction
– Air Purification
15 45
Extraction – Filtration – Crystallization – Emulsification 15 45
Tablets – Powder flow 15 45
Heat flow – Evaporation - GMP 15 45
5-Teaching and learning methods: 1- Lectures
2- Practical Sessions
1- .......................Group discussion.
-Teaching and learning methods for disables
(Student assessment) 6-Student assessment methods: 1– Reports to asses data collection skills
2- Final written exam to assess intellectual skills.
3- Oral Exam.
-Assessment schedule)
no Exam Week
1 Final-Term Examination Final week
2 Oral Examination Final week
3 Practical Examination Final week
7- Weighing of assessments:
Exam degree %
Midterm Exam
5 5
Final Exam 50 50
Oral exam 15 15
Practical exam 30 30
Total 100 100%
14
8-List of references:
a-Course notes (the department note book)
b-Essential books, (Text books) e.g. Pharmaceutical dosage
forms,tablets, vol 1,2,3 1996. Pharmaceutics, the science of
dosage formd design, M.Aulton
c-Recommended books, e.g. Pharmaceutical
encyclopedia, Remington pharmaceutical sciences.
d-Periodicals, Web sites……etc)
9-Facilities required for teaching and learning
a-Power poit
b-Over head projector
Course Coordinator: Prof. Dr. Ahmed Abutaleb,Prof.Dr. Ali
Abdel-Zaher, Prof. Dr. Eman Samy and Prof. Dr. Mahrous
Osman Ahmed
Head of Department: Prof. Dr. Sayed Ibrahim Abdel-Rahman
15
Course specification
1-Basic Information Title: Lab Safety Code: DP-IP 063
Level : Deploma of Pharmaceutical Technology
Department : Industrial Pharmacy
Unit:
Lecture: 1 hour/week Tutorial: Practical: Total:
2-Aims of Course The student will be gain the safety measures in factories,
taking the considerations of safety in building design, equipments, and industrial processes. 1- Intended learning outcomes of course (ILO's)
a-Knowwledge and understanding:
a1- Academic informations about security of factories.
a 2- Methods of protection in case of emergencies as fire.
b-Intellectual skills:
b1- How facing the the emergency difficulties.
b2- Finding the suitable solutions in optimum time at
occurance of suddenly dangerous problems. c-Professional and practical skills:
How handling with tools and equipments specified for safety
for example fire safe.
d-General and transferable skills
d1-How deal with the team work.
D2-Transfer the gained experts to the new workers in
association.
Assiut University
Faculty of Pharmacy
Quality Assurance Unit
Ind. Pharmacy Dept. Course Specification
16
2- Course contents: Hours Subjects
Lectures Practical/tutorial
Measures of safety in factories 6 -
Importants consideration in building design 6 -
Equipments and industrial processes 6 -
Tools of special protection 6 -
Protection in cases of fire 6 -
5-Teaching and learning methods -Lectures - Discussion - Term activities
6-Teaching and learning methods for disables
7-Student assessment a-Student assessment methods:
- Written exam - Oral exam
b-Assessment schedule: No. Exam week
1 Written End year
2 Oral End year
c-Weighing of assessment:
Exam degree %
Midterm Exam - -
Final Exam 40 80%
Oral Exam 10 20%
Practical Exam - -
Total 50 100%
8-List of references:
a-Course notes (the department note book)
b-Essential books, (Text books)
c-Recommended books
d-Periodicals, Web sites……etc)
9-Facilities required for teaching and learning
a-Power poit
b-Over head projector
17
Course Coordinator: Prof.Dr. Ali Abdel-Zaher, Prof. Dr. Sayed
Khider and Prof. Dr. Mahrous Osman Ahmed
Head of Department: Prof. Dr. Sayed Ibrahim Abdel-Rahman