Course specification Diploma - Assiut University€¦ · Applications and problems 3 2 Principals...

Course Specification

1-Basic Information

Title: Advanced biological pharmacy Code: DP-IP 061

Level: Diploma of Pharmaceutical Technology Department: Pharmaceutics

Unit: 3

Lecture: Two hours per week Tutorial: Practical: 1 hours Total: 3 hr/week

2- Aims of Course

This course aims to:

1- Help students to identify the factors that help on the bioavailability of the drug in

the body and the factors which help the absorption of drug into the blood.

2- Give the student knowledge on the application of the pharmacokinetic of the drug

within the body and calculate the rate of absorption and the rate of elimination of the

drug, as well as the half-life of the drug.

3- Intended Learning Outcomes of Course (ILOs):

a- Knowledge and Understanding:

By the end of the diploma, the students will be able to:

al- Be aware of the basic pharmacokinetic parameters of the drug.

a2- List factors that affects the pharmacokinetic parameters of the drug such as

rate of absorption, volume of distribution as well as rate of elimination.

a3- Be aware of other factors that affect the bioavailability of drug in the body

such as condition of the patient and age.

b- Intellectual Skills:


b1- Identify the factors that affect the absorption of the drug from the body.

b2- Analyze the mechanism of absorption of the drug from the gastrointestinal

tract.

b3- Evaluate biological factors that affect the bioavailability of the drug.

Assiut University

Faculty of Pharmacy

2

c- Professional and practical Skills:


c1- Calculate the area under the curve..

c2- Calculate the absolute bioavailability.

c3- Calculate the relative bioavailability.

c4- Determine the factors affecting the drug bound to plasma proteins.

d- General and Transferable Skills:


d1- Write a detailed report on the factors that affect the bioavailability of the

drug.

d2- Use information technology in the field of drug bioavailability.

d3- Improve his knowledge continuously through self learning.

Course Contents

Topic No. of hours Lecture Tutorial / Practical

Introduction 2

Factors affecting drug

absorption

A - physical factors

B - biological agents

8

8

Pharmacokinetic absorption

of the drug

8

Methods of drug absorption 8

Drug elimination 8

Plasma proteins binding 8

Total 50

4- Teaching and Learning Methods

4.1- Lecturers

4.2- Discussions

4.3- Seminars

4.4- Reports

5- Teaching and learning methods for disables 1- Allocation of additional time to explain what is not understandable to those

students.

2 - Providing specialized places for these students

6- Student Assessment

a- Student Assessment methods

6.1- Final written exam to assess knowledge and understanding

6.2- Oral exam to assess knowledge and intellectual skills

3

b- Student Assessment Schedule

No. Assessment week

1. Final written exam In November

2.

3.

4.

c- Weighting of Assessments

No. Exam. Mark %

1. Mid-Term Examination - -

2. Final-Term Examination 50 50%

3. Oral Examination 20 20%

4. Practical Examination 30 30%

5. Semester Work - -

6- Other types of assessment - -

Total 100 100%

7- List of References

a- Course Notes ………………………………………………

b- Essential Books (Text Books) Applied Biopharmaeutics and pharmacokinetics by Lion Shargel

c-Recommended Books

Textbook of Biopharmaceutics and Pharmacokinetics by Naizi

d- Periodicals, Web Sites, …. etc ………………………………………………

………………………………………………

8- Facilities Required for Teaching and Learning …………………………………………………………………………

Course Coordinator: Professor Dr. Sayed Ismail

Head of Department: Professor Dr. Frgani Abdel-Hamid

4

University Assiut

Course Title Advanced biological

pharmacy

Faculty Pharmacy

Course Cod. ......................................

Department Pharmaceutics

Matrix of the Intended Learning Outcomes (ILOs) of the Course

General and Transferable

Skills

Professional and

Practical Skills Intellectual Skills

Knowledge and

Understanding Week Topic

a1,a2,a3 1st Introduction

d1 b1, b2,b3 a1 a2,a3 2nd

- 6th

Factors affecting drug

absorption

A - Physical factors

B - Biological agents

d1,d2,d3 c1,c2,c3 b1, b2,b3 a1 a2,a3 7th

,9th

Pharmacokinetic

absorption of the drug

d1,d2,d3 b1, b2,b3 a1 a2,a3 10th

, 11th

Methods of drug

absorption

d1,d2,d3 c1,c2,c3 b1, b2,b3 a1 a2,a3 12th

, 13th

Drug elimination

d1,d2,d3 c4 a1 a2,a3 14th

, 15th

Plasma proteins binding



5

Course specification

1-Basic Information Title: Advanced Industrial Pharmacy Code: DP-IP 064

Level : Deploma of Pharmaceutical Technology

Department : Industrial Pharmacy

Unit:

Lecture: 3 hours/week Practical: 6 hours/week Total: 9hours/week

2-Aims of Course Aims of Course: are to provide the students with basic as well as

applied knowledge in the field of pharmaceutical technology.

3-Intended Learning Outcomes (ILO's)

a- Knowwledge and understanding a1- Basic knowledge about some advanced industrial pharmaceutical

topics.

a2- Regulatory information.

b- Intellectual skills: b1- Formulation design in some novel drug delivery systems.

b2- Problem solving.

c- Professional and practical skills:

c1- Instrumentation of tablet machine.

c2- Sterile area design in pharmaceutical industry.

d- General and transferable skills:

d1- Scale-up and technology transfer in tablet production.

d2- Basics of total quality assurance in pharmaceutical imanufacturing.

Assiut University

Faculty of Pharmacy

Quality Assurance Unit

Ind. Pharmacy Dept. Course Specification

6

4-Course contents:

Hours Subjects

Lecture Practical

Material of constructions and Corrosion. 9 18

Sterile Area 9 18

Sustained release 9 18

Liposomes 9 18

Transdermal delivery system 9 18

Total quality Assurance 9 18

International standard operation (ISO) 9 18

Validation 9 18

Instrumentation of tablet machine 9 18

Scale-up technology – 9 18

5-Teaching and learning methods: 1- Lectures using data show

2- Group discussion

3- Practical sessions

Teaching and learning methods for disables)

6-Student assessment (Student assessment methods): 1- Final exam

2- Practical exam

3- Oral exam

7-Assessment schedule

No. Exam Week

1 Final Exam End year

2 Oral Exam End year

3 Practical Exam During year

-Weighing of assessments:

Exam Degree %

Midterm exam 5 3.3

Final exam 75 50

Oral exam 25 16.7

Practical exam 45 30

Total 150 100

8-List of references:

a-Course notes (the department note book)

7

b-Essential books, (Text books) e.g. Pharmaceutical dosage

forms,tablets, vol 1,2,3 1996. Pharmaceutics, the science of

dosage formd design, M.Aulton

c-Recommended books, e.g. Pharmaceutical

encyclopedia, Remington pharmaceutical sciences.

d-Periodicals, Web sites……etc)

9-Facilities required for teaching and learning

a-Power poit

b-Over head projector

Course Coordinator: Prof. Dr. Ahmed Abutaleb,Prof.Dr. Ali

Abdel-Zaher, Prof. Dr. Eman Samy and Prof. Dr. Mahrous

Osman Ahmed Head of Department: Prof. Dr. Sayed Ibrahim Abdel-Rahman

8


1-Basic Information

Title: Advanced Physical Pharmacy Code: DP-IP 062

Level: Diploma of Pharmaceutical Technology

Department: Industrial Pharmacy

Unit:

Lecture: Two hours per week Tutorial: Practical: 4 hours Total: 6 hr/week

2- Aims of Course

This course aims to help students to know:

1- Different methods used in solubilizing drugs and their equations.

2- Methods of diffusion of drugs.

3- Drug stability and calculation of expiration date.

3- Intended Learning Outcomes of Course (ILOs)

a- Knowledge and Understanding:


al- Be aware of the basics mechanisms of diffusion of drug from gels.

a2- Describe the mechanism of release of drugs from pharmaceutical preparations.

a3- Illustrate the rate of drug degradation in the pharmaceutical preparation.

a4- Be aware of the interactions between drugs and excipient.

b- Intellectual Skills:


b1- Improve the rate of solubilization of some drugs.

b2- Increase the stability of the drug at room temperature

b3- Calculate the half-life of drugs.

b4- Calculate the expiration date of drugs


Assiut University

Faculty of Pharmacy

9

c- Professional and practical Skills:


c1- Contribute in solving the problems of drugs, such as, the rate of

solubilzation, diffusion, and stability.

c2- Suggest the best ways to store the drug.

d- General and Transferable Skills:


d1- Communicate with the research team in the pharmaceutical companies to

design the best formulation of the drug.

d2- Use a variety of scientific sources such as journals and the Internet.

d3- Ability to solve the problems of drug stability

Course Contents

Topic No. of hours Lecture Tutorial / Practical

Introduction 2 2

Types of drug degradations

a- Physical

b- Chemical

10 6

Expiration date 5 2

Applications and problems 3 2

Principals of drug diffusion 10 2

Drug release 10 2

Drug interactions 10 2

Applications 10 2

Total 60 20

4- Teaching and Learning Methods

4.1- Lecturers

4.2- Practical studies

4.3- Reports

4.4- Seminars

5- Teaching and learning methods for disables

1- Allocation of additional time to explain what is not understandable to those

students.

2 - Providing specialized places for these students

6- Student Assessment

a- Student Assessment methods 6.1- Written exam to assess knowledge and understanding

6.2- Practical exam to assess professional and practical Skills

6.3- Oral exam to assess knowledge and intellectual Skills

10

c- Student Assessment Schedule

No. Assessment week

1. Final exam In November

2.

3.

4.

c- Weighting of Assessments

No. Exam. Mark %

1. Mid-Term Examination - -

2. Final-Term Examination 50 50%

3. Oral Examination 20 20%

4. Practical Examination 30 30%

5. Semester Work - -

6- Other types of assessment - -

Total 100 100%

7- List of References

a- Course Notes ………………………………………………

b- Essential Books (Text Books) - Physical pharmacy by A-Marlin

- Remington, the science and practice of pharmacy.

c- Recommended Books - The theory and practice of industrial pharmacy Leon Lachman, Liberman and

Kanig

- Pharmaceutics, the science of dosage forms by M.E. Aulton.

d- Periodicals, Web Sites, …. etc ………………………………………………

8- Facilities Required for Teaching and Learning …………………………………………………………………………



11

University Assiut

Course Title Advanced Physical

Pharmacy

Faculty Pharmacy

Course Cod. ......................................

Department Pharmaceutics

Matrix of the Intended Learning Outcomes (ILOs) of the Course

General and Transferable

Skills

Professional and

Practical Skills Intellectual Skills

Knowledge and

Understanding Week Topic

a2 1st Introduction

d1, d2,d3 c1, c2 a3 2nd

, 4th

Types of drug

degradations

a- Physical

b- Chemical

d1, d2,d3 c1, c2 b4 5th

Expiration date

d1, d2,d3 c1, c2 b2, b3,b4 6th

Applications and

problems

d1, d2,d3 a1 7th

, 9th

Principals of drug

diffusion

d1, d2,d3 c1, c2 a2 10th

, 12th

Drug release

d1, d2,d3 c1, c2 a4 13th

, 14th

Drug interactions

d1, d2,d3 c1, c2 b2, b3,b4 15th

Applications



12


1-Basic Information Title: Industrial Engineering Code: DP-IP 065



Unit:

Lecture: 2 hours/week Practical: 6 hours/week Total: 8hours/week

2-Aims of Course

Provide the students with the principles, concepts and theories for the unit

operating used in Pharmaceutical industry.

3-Intended Learning Outcomes (ILO's) :

a- Knowwledge and understanding al- Application of different techniques in drug industry.

a2-Understanding the basic fundamentals of various unit operations.

a3- Gaining information about the current good manufacturing practice.

b-Intellectual skills: b1- Application of mathematical knowledge.

b2- Logic thinking and rational proceeding.

c- Professional and practical skills:

cl – Understanding the basics of unit operations.

c2- Acquiring the ability of problem solving.

d-General and transferable skills:

d1-Working in a team work.

d2-Practical application of theoretical information.

Assiut University

Faculty of Pharmacy



13

4-Course contents:

Hours Subject

Lectures Practical

Drying - Mixing – Particle size analysis – Size reduction

– Air Purification

15 45

Extraction – Filtration – Crystallization – Emulsification 15 45

Tablets – Powder flow 15 45

Heat flow – Evaporation - GMP 15 45

5-Teaching and learning methods: 1- Lectures

2- Practical Sessions

1- .......................Group discussion.

-Teaching and learning methods for disables

(Student assessment) 6-Student assessment methods: 1– Reports to asses data collection skills

2- Final written exam to assess intellectual skills.

3- Oral Exam.

-Assessment schedule)

no Exam Week

1 Final-Term Examination Final week

2 Oral Examination Final week

3 Practical Examination Final week

7- Weighing of assessments:

Exam degree %

Midterm Exam

5 5

Final Exam 50 50

Oral exam 15 15

Practical exam 30 30

Total 100 100%

14



b-Essential books, (Text books) e.g. Pharmaceutical dosage

forms,tablets, vol 1,2,3 1996. Pharmaceutics, the science of

dosage formd design, M.Aulton

c-Recommended books, e.g. Pharmaceutical

encyclopedia, Remington pharmaceutical sciences.



a-Power poit


Course Coordinator: Prof. Dr. Ahmed Abutaleb,Prof.Dr. Ali

Abdel-Zaher, Prof. Dr. Eman Samy and Prof. Dr. Mahrous

Osman Ahmed

Head of Department: Prof. Dr. Sayed Ibrahim Abdel-Rahman

15


1-Basic Information Title: Lab Safety Code: DP-IP 063



Unit:

Lecture: 1 hour/week Tutorial: Practical: Total:

2-Aims of Course The student will be gain the safety measures in factories,

taking the considerations of safety in building design, equipments, and industrial processes. 1- Intended learning outcomes of course (ILO's)

a-Knowwledge and understanding:

a1- Academic informations about security of factories.

a 2- Methods of protection in case of emergencies as fire.

b-Intellectual skills:

b1- How facing the the emergency difficulties.

b2- Finding the suitable solutions in optimum time at

occurance of suddenly dangerous problems. c-Professional and practical skills:

How handling with tools and equipments specified for safety

for example fire safe.

d-General and transferable skills

d1-How deal with the team work.

D2-Transfer the gained experts to the new workers in

association.

Assiut University

Faculty of Pharmacy



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2- Course contents: Hours Subjects

Lectures Practical/tutorial

Measures of safety in factories 6 -

Importants consideration in building design 6 -

Equipments and industrial processes 6 -

Tools of special protection 6 -

Protection in cases of fire 6 -

5-Teaching and learning methods -Lectures - Discussion - Term activities

6-Teaching and learning methods for disables

7-Student assessment a-Student assessment methods:

- Written exam - Oral exam

b-Assessment schedule: No. Exam week

1 Written End year

2 Oral End year

c-Weighing of assessment:

Exam degree %

Midterm Exam - -

Final Exam 40 80%

Oral Exam 10 20%

Practical Exam - -

Total 50 100%



b-Essential books, (Text books)

c-Recommended books



a-Power poit


17

Course Coordinator: Prof.Dr. Ali Abdel-Zaher, Prof. Dr. Sayed

Khider and Prof. Dr. Mahrous Osman Ahmed

Head of Department: Prof. Dr. Sayed Ibrahim Abdel-Rahman

Course specification Diploma - Assiut University€¦ · Applications and problems 3 2 Principals...

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