Post on 24-Sep-2020
528
ANNEXURE – 15
CHOICE BASED CREDIT SYSTEM – STRUCTURE
FROM THE ACADEMIC YEAR 2014–15
B.Sc BIOCHEMISTRY
SEM Part – I Part – II Part – III Part – IV
Part – V
(6th Hr)
ACC
(6th Hr) SLC
I
Sem.
I
Lang
(6)
II Lang
(6)
Core
(4)
Core
(4)
Core Lab
(2)
Allied Che.
(4)
Allied Che.Lab
(2)
SBE
(2) –
Total
(30)
NCC/NSS/PED.
(3)
Com.Eng
(2)
Comp.Lit
(1) – –
II
Sem.
I
Lang
(6)
II
Lang
(6)
Core
(3)
Core
(4)
Core
Lab
(2)
Allied
Che.
(4)
Allied
Che.Lab
(2)
SBE
(2)
Elec.
EVS
(1)
Total
(30)
NCC/NSS/PED.
(3)
Com.Eng
(2)
Comp.Lit
(1) –
Law
&
Society
III
Sem.
I
Lang
(6)
II Lang
(6)
Core
(6)
Core Lab
(2)
Allied Bio.
(4)
Allied Bio.Lab
(2)
- NME
(2)
SBE
(2)
Total
(30)
NCC/NSS/PED.
(3)
Com.Eng
(2)
Comp.Lit
(1) – Human Rights
IV
Sem.
I
Lang (6)
II
Lang (6)
Core
(6)
Core
Lab (2)
Allied
Bio. (4)
Allied
Bio.Lab (2)
- NME
(2)
SBE
(2)
Total
(30)
NCC/NSS/PED.
(3)
Com.Eng
(2)
Comp.Lit
(1) –
Food Science
V
Sem.
Core
(6)
Core
(5)
Core
(5)
Core
(5)
Elec.I
(6) - -
SBE
(2)
Elec. W.S.
(1)
Total
(30) –
Com.Eng
(2)
Comp.Lit
(1)
Skill Devt – Career Guidance
(3)
Medical
Pharmacology
VI Sem.
Core (4)
Core (4)
Core
Lab
(3)
Core
Lab
(3)
Elec-II. (6)
Elec.III
Project
(6)
SBE (2)
Elec.
VBE
(2)
Total (30)
– Com.Eng
(2) Comp.Lit
(1)
Skill Devt –
Career Guidance
(3)
––
Total 180 Hrs
I Language – Tamil
II Language – English
SBE – Skill – Based Electives
SLC – Self – Learning Course
EVS – Environmental Studies
W.S. – Women Studies
529
CHOICE BASED CREDIT SYSTEM – STRUCTURE
FOR THOSE WHO HAVE JOINED FROM THE ACADEMIC YEAR 2014–15 ONWARDS
B.Sc BIOCHEMISTRY
Sem
Part
Course Subject Hrs. 6th
Hr. Cr.
Adl.
Cr.
Exam
(Hrs)
Marks Allotted
Int. Ext.
I
I Lang. – I Tamil – I 6 3 3 25 75
II Lang. – II General English – I 6 3 3 25 75
III
Core Fundamentals of
Biochemistry 4 4 3 25 75
Core Biomolecules 4 4 3 25 75
Core Lab Lab in Qualitative Analysis
and Enzyme Kinetics 2 – – – –
Allied
Che. General Chemistry – I 4 4 3 25 75
Allied
Che. Lab Volumetric Analysis Lab – II 2 – – – –
IV SBE - I Human Physiology 2 2 2 25 75
V Extension
activities NSS / NCC / PED 3 – – –
Additional
Courses
Communicative English–I 2 – – –
Computer Literacy 1 – – –
II
I Lang. – I Tamil – II 6 3 3 25 75
II Lang. – II General English – II 6 3 3 25 75
III
Core Enzymes 3 3 3 25 75
Core Metabolism – I 4 4 3 25 75
Core Lab Lab in Qualitative Analysis
and Enzyme Kinetics 2 2 3 40 60
Allied
Che. General Chemistry – II 4 4 3 25 75
Allied
Che. Lab
Volumetric Analysis
Lab – II 2 2 3 40 60
IV SBE - II Viriology 2 2 2 25 75
EVS Environmental Studies 1 1 2 – 100
V Extension
activities NSS / NCC / PED 3 – – –
Additional
Courses
Communicative English–I 2 1 3 25 75
Computer Literacy 1 – – –
S L C Law and Society 3 3 – 100
530
Sem
Part
Course Subject Hrs.
6th
Hr. Cr.
Adl.
Cr.
Exam
(Hrs)
Marks Allotted
Int. Ext.
III
I Lang. – I Tamil – III 6 3 3 25 75
II Lang. – II General English – III 6 3 3 25 75
III
Core Metabolism – II 6 5 3 25 75
Core Lab Lab in Quantitative Analysis
of Bimolecules 2 – –
– –
Allied Bio. Cytology 4 4 3 25 75
Allied Bio.
Lab
Lab in Cytology and Human
Genetics 2 – –
– –
IV
NME - I Environmental Pollution –
Health and Toxicology 2 2 2 25 75
SBE - III Genetic Engineering 2 2 2 25 75
V Extension
activities NSS / NCC / PED 3 –
– –
Additional
Courses
Communicative English–II 2 – – –
Computer Literacy 1 – – –
SLC Human Rights 3 3 – 100
IV
I Lang. – I Tamil – IV 6 3 3 25 75
II Lang. – II General English – IV 6 3 3 25 75
III
Core Biophysical and Biochemical
Techniques 6 5 3
25 75
Core Lab Lab in Quantitative Analysis
of Bimolecules 2 2 3
40 60
Allied Bio. Human Genetics 4 4 3 25 75
Allied Bio.
Lab
Lab in Cytology and Human
Genetics 2 2 3
40 60
IV
NME - II Medical Biochemistry 2 2 2 25 75
SBE- IV Biotechnology 2 2 2 25 75
V Extension
activities NSS / NCC* / PED* 3 1 3
25
*40
75
*60
Additional
Courses
Communicative English–II 2 1 3 25 75
Computer Literacy 1 – – –
SLC Food Science 4 3 – 100
531
Sem
Part
Course Subject Hrs.
6th
Hr. Cr.
Adl.
Cr.
Exam
(Hrs)
Marks
Allotted
Int. Ext.
V
III
Core Clinical Biochemistry – I 6 5 3 25 75
Core Molecular Biology 5 4 3 25 75
Core Microbiology 5 4 3 25 75
Core Immunochemistry 5 4 3 25 75
Elec.- I Biochem. paper (1) and (2)
Any one from
6 5 – 40 [*30:@10]
60 [*50:@10
]
IV SBE - V Medical Lab Technology 2 2 2 25 75
WS Women Studies 1 1 2 – 100
Additional Courses
Communicative English–III 2 – – –
Computer Literacy 1 – – –
Skill Development – Career
Guidance 3 – – –
SLC Medical Pharmacology 4 3 - 100
VI
III
Core Clinical Biochemistry – II 4 4 3 25 75
Core Plant Biochemistry 4 4 3 25 75
Core Lab Lab in Micro Biology and
Molecular Biology 3 3 3 40 60
Core Lab Lab in Clinical Biochemistry 3 3 3 40 60
Elect. - II Biochem. paper (1) and (2)
Any one from
6 5 3 25 75
Elect.- III
Project
*Report;@Viva 6 5 3 25 75
VI SBE - VI Bio physics 2 2 2 25 75
VBE Value Based Education 2 2 2 – 100
Additional
Courses
Communicative English–III 2 1 3 25 75
Computer Literacy 1 1 3 – 100
Skill Development – Career
Guidance 3 2 3 – 100
TOTAL 180 36 140 20
*Elective I and II: Each Elective paper has two choices, select any one from.
1.1. Genomics
1.2. Biostatistics
2.1. Endocrinology
2.2. Bioinformatics
532
ALLIED – BIOLOGY FOR BIOCHEMISTRY
Sem Title of the Paper
Hrs.
Cr. Exam
(Hrs)
Marks Allotted
Int. Ext.
III Cytology 4 4 3 25 75
IV Human Genetics 4 4 3 25 75
IV Lab in Cytology and Human
Genetics 2 2 3 40 60
V Biostatistics 3 3 3 25 75
VI Human Physiology 3 3 3 25 75
VI Lab in Biostatistics and Human Physiology
2 2 3 40 60
533
B.Sc BIOCHEMISTRY: Those Who Have Joined From The
Academic Year 2014–15 Onwards Under CBCS System
Core Subject METABOLISM – II Code: 14283301
SEMESTER III
6 Hrs/Week
Credits 5
Objectives:
To educate students in the areas of primary and secondary
metabolism.
To gain new information about organizational metabolism.
UNIT – I: [18 Hrs]
Nucleic acid Metabolism – Purine and Pyrimidine bases –
Biosynthesis of Purines and Pyrimidines – biosynthesis of DNA and
RNA.
UNIT – II: [18 Hrs]
Mineral Metabolism – a brief account, Blood cells, Blood groups
– Blood coagulation – Blood transfusion, Compatibility.
UNIT – III: [18 Hrs]
Hormones – definition – classification – mechanisms of action of
hormones and signal transduction.
UNIT – IV: [18 Hrs]
Function of the Pancreas, thyroid and adrenal glands, Steroid
metabolism Biological effects of androgens and estrogens.
UNIT – V: [18 Hrs]
Neurochemistry – Synapse – Neuro transmitters, receptors.
TEXT BOOK:
01. Robert K. Murray, Peter A. Meyes, Victor W. Roadwell, Harper’s
illustrated Biochemistry, 26th Edition, McGraw – Hill, Bosten,
2003.
REFERENCES:
01. Albert L., Lehinger, Principles of Biochemistry, CBS publishers
and Distributors.2nd edition, New Delhi, 2003.
02. Donald Voet and Judith Voet, Biochemistry, Wiley International
2nd Edition, New York, 2006.
03. Gerald carp, Cell and Molecular Biology, 3rd edition, John Wiley
and Sons. Inc, New York, 2003.
04. Lubert Stryer et at, Biochemistry, 7th edition, W.H.Freeman and
Company, New York, 2012.
534
Part – IV ENVIRONMENTAL POLLUTION – HEALTH AND TOXICOLOGY Non-Major Electives SEMESTER III Code: 14463328
2 Hrs/Week
Credits 2
Objectives:
To assess environmental factors that influence human health and
quality of life, and seeks to prevent adverse effects on human health
and ecological systems.
UNIT – I: [6 Hrs]
Introduction – Types of Pollution, Sources of Pollution, Persisted
Organic Pollutants, Environmental mobility of Pollutants.
Air Pollution – Classification and properties of air pollutants,
behaviour and fate of air pollutants – Wet precipitation, dry deposition,
Interaction at the earth’s surface, Nature and development of acid rain
- Acid rain and aquatic terrestrial and the Built environment, Effects
of air pollution, Indoor air pollution, Prevention and control of air
pollution.
UNIT – II: [6 Hrs]
Water and Land Pollution – Origin of waste water – Domestic
Water Pollution, Industrial Water Pollution, Oil Pollution – Toxic Water
Pollutants and their effects – Minamata disease, Pollution problems of
leather industries.
Noise Pollution – Sources and effects, Radio active Pollution –
Natural and man made incidents of radioactive pollution – Hiroshima
Catastrophe, Chernobyl accident – Radioactive contamination of River
Periyar.
UNIT – III: [6 Hrs]
Environment and Community Health: Epidemiologic concepts of
disease – Malaria – Effects, Environment factors, agent factors, host
factors, vector of malaria – Mode of transmission, Malaria control
strategies – Biological Control.
Tuberculosis – Agent factors, host factors, social factors, mode of
transmission, control of tuberculosis.
UNIT – IV: [6 Hrs]
Occupational hazards – Physical, Chemical, Biological,
Psychosocial hazards. Asbestosis, lead poisoning, Occupational
cancer.
UNIT – V: [6 Hrs]
Toxicology – Environmental toxicology – Exposure,
bioaccumulation, biomagnifications, Portal entry of a toxin,
Metabolism of toxin, Nature of toxin effects in human – Heavy metal
toxicity – Arsenic, Cadmium, Alcohol toxicity, Pesticides toxicity.
535
TEXT BOOK: 01. Rana S.V.S., Environmental Pollution-Health and Toxicology,
Narosa Publishing House Private Limited, 1st Reprint, 2007. REFERENCE:
01. Sharma B.K., Environmental Chemistry,1st edition, Goel Publishing House, Meerut. 1992
Part – IV GENETIC ENGINEERING Code: 14443328
Skill Based Electives SEMESTER III
2 Hrs/Week
Credits 2
Objectives:
To understand invitees DNA technologis that are used to isolate genes
from an organisims manipulate them into another cell systems for
specific genetic trait.
UNIT – I: [6 Hrs]
DNA Cloning: Restriction enzymes, complementary DNA,
cloning vectors, – pBR 322 cosmids, Plasmids, Ligation of sticky ends,
blunt end ligation, homopolymer tailing. Techniques involved in
transfer of genes in E coli.
UNIT – II: [6 Hrs]
Detection and characterization of recombinants – Gene markers,
Plus and Minus Screening, Immunochemical methods, hybridization
methods.
UNIT – III: [6 Hrs]
Gene Manipulation in Plants: Transgenic plants, Gene transfer
through Agrobacterium tumefaciens, Herbicide resistant plants, virus
resistant plants, pest resistant plants.
UNIT – IV: [6 Hrs]
Transgenic animals - methods, gene therapy– gene knock out.
UNIT – V: [6 Hrs]
Human Genome project, DNA micro array, DNA finger printing –
PCR, RFLP, RAPD.
TEXT BOOKS:
01. Bernard R.Glick, Molecular Biotechnology – Principles and Applications of Recombinant DNA, 2nd edition,1998 ASM Press, Washington, D C.
02. James D.Watson Michacl Gilman, Recombinant DNA, 2nd Edition,1928 Scientific American Books, New York.
03. Old and Primrose S.B., Principles of Gene Maniputiulation, 2nd
Edition,1994, Blackwell Scientific Publication, London.
REFERENCES:
01. Brown C.M., Campbell I., Priest F.G., Introduction to Bio
Technology, Blackwell Scientific Publications, London, 1998.
02. Pamela Peters, Biotechnology, A Guide to genetic engineering,
WCB McGraw – Hill, Boston, 1988.
536
Core Subject BIOPHYSICAL AND BIOCHEMICAL TECHNIQUES
SEMESTER IV Code: 14283401
6 Hrs/Week
Credits 5
Objectives:
To understand the basic principles of techniques that are used
routinely in modern biochemistry and molecular biology.
UNIT – I: [18 Hrs]
Chromatography: Column, Paper and Thin layer
chromatography, Adsorption, Partition, Ion exchange, Gas
Chromatography and HPLC. Gel filtration and Dialysis.
UNIT – II: [18 Hrs]
Electrophoresis – Principles – Instrumentation and Application –
Agarose, SDS-PAGE; Principles and application of PCR.
UNIT – III: [18 Hrs]
Centrifugation – Theory, relation between rpm and g –
Differential centrifugation, density gradient – Different types of
centrifuges, Measurement of Gases – Manometry.
UNIT – IV: [18 Hrs]
Colorimetry: Light spectrums and its wavelength regions –
complementary colours. Molar Extinction co-efficient. Beer Lambert’s
law and its application.
UNIT – V: [18 Hrs]
Radioisotopes in Biochemistry, Radioactivity, Elementary Units,
Deduction of radioactivity – Autoradiography, fluorography, isotopic
trace technique, Isotope dilution method
TEXT BOOK: 01. Upadhay, Upadhay, Nath, 3rdedition,1 998, Biophysical
Chemistry, Principles and Techniques, Himalaya Publishing House, Bombay.
REFERENCE:
01. Wilson and Walker, Practical Biochemistry, 5th Edition, 1994, Principles and Techniques Cambridge low-price Editions,
Cambridge University Press.
Core Lab LAB IN QUANTITATIVE ANALYSIS OF BIMOLECULES SEMESTER III & IV Code: 14283402
2 Hrs/Week
Credits 2
Objectives:
To gain knowledge about the quantitative analysis of Biomolecules and
their
01. Estimation of glucose by Phenol Sulphuric acid Method
02. Estimation of proteins by Lowry’s method.
537
03. Estimation of fructose by Seliwanoff’s methods.
04. Estimation of pentose by Bials methods.
05. Estimation of Ascorbic acid (Colorimetric/Titrimetry)
06. Estimation of reducing sugar in fruits.
07. Estimation of Lactose in milk.
08. Estimation of DNA.
09. Estimation of RNA.
10. Separation of amino acids by Paper Chromatography.
11. Separation of amino acids by TLC.
12. Separation of proteins by SDS-PAGE.
13. Identification of Nucleic acids by Agarose gel eletrophoresis.
14. Protein purification – Protein precipitation, Dilaysis, Column
Chromatography (Demonstration Only)
REFERENCES:
01. Palanivelu P., Laboratory Manual for Analytical Biochemistry
and Separation Techniques ,4th edition 2009.
02. Pattabiraman, Lab Manual in Biochemistry,3rd edition,1998, All
India Publishers & Distributor, Chennai.
03. Sadashivam, Biochemical Mehods, 1996,New Age International
Publishers, New Delhi,
04. Varley, Practical Clinical Biochemistry, 6th Edition,1988, CBS
Publishers, New Delhi.
Part – IV MEDICAL BIOCHEMISTRY Code: 14463428
Non-Major Electives SEMESTER IV 2 Hrs/Week
Credits 2 Objectives:
To develop and integrates a basic research program with clinical
practice in a field of biochemical interest, and maintains an active
role as a teacher of clinically applied Bio chemistry.
UNIT – I: [6 Hrs]
Basic Medical Biochemistry: Units of measurement; Weight,
Volume, Temperature and Viscosity, Concentration; Normality,
Molarity, Molality and PPM. Biochemical tech; pH, Buffer, Dialyais,
Osmosis.
UNIT – II: [6 Hrs]
Chemistry of Biomolecules: The cell, Carbohydrates, Proteins,
Lipids and Nucleic Acids, Chemistry of Blood – SGOT and SGPT,
Biological Oxidation, Vitamins, Immunoglobulins and Prostaglandins.
UNIT – III: [6 Hrs]
Function Tests: Renal, Liver, test for pregnancy and ELISA.
UNIT – IV: [6 Hrs]
Disease and Disorders: AIDS, Diabetes, Cancer, Anaemia,
Tuberculosis, Fever and water borne diseases. [cholera]
538
Heart Diseases: (Atherosclerosis, Pulmonary Embolism and
Myocardial infarctions).
UNIT – V: [6 Hrs]
Liver Diseases: (Jaundice and alcoholic cirrhosis).
Kidney Diseases: (Glomerular Nephritis, Acute and Chronic
Renal Failure).
Brain Disorder-Alzheimier’s Disesase.
TEXT BOOKS:
01. Chatterjee M.N., Text Book of Medical Biochemistry, 6th Edition,
2005, Jaypere Brother’s.
02. Ramakrishnan S., Text Book of Medical Biochemistry, 2nd
Edition, 1998, Orient Longman.
REFERENCES:
01. Alan H.Gowenlock, Varleys Practical Clinical Biochemistry, 6th
Edition, 2002, CBS Publisher, New Delhi.
02. Harrison’s, Principles of Internal Medicine, Vol. I and II,
McGraw – Hill.16th edition, 2005.
Part – IV BIOTECHNOLOGY Code: 14443428
Skill Based Electives SEMESTER IV
2 Hrs/Week
Credits 2
Objectives:
To update the application of biotechnology in various fields.
UNIT – I: [6 Hrs]
Introduction to Biotechnology – Restriction enzymes and DNA
ligases, Introduction to gene cloning – types of cloning vectors –
plasmid, phagemid, cosmid, M13 phage, BAI, YAC.
UNIT – II: [6 Hrs]
Plant Biotechnology: Agrobacterium mediated gene transfer,
transgenic plants and its applications, crop improvement.
UNIT – III: [6 Hrs]
Animal Biotechnology: Viral vector system – Bacterio viral vector,
methods for producing transgenic animal – Micro injection – Electro
poration – gene gun method – Invitro fertilization and embryo transfer.
Application of transgenic animal.
UNIT – IV: [6 Hrs]
Microbial Biotechnology: Basic principles of microbial growth –
types – design and operation of fermentors, microbial degradation of
oil spills, Biodegradable plastics.
UNIT – V: [6 Hrs]
Production of recombinant proteins: insulin, interferon and
vaccines, treatment of various human disorders, gene therapy.
539
TEXT BOOK: 01.Bernard R.Glick, and Jack J.Pasternek, Molecular
Biotechnology, 2nd Edition, ASM Press, Washington, 1998. 02.James D.Watson Michacl Gilman, Recombinant DNA, 2nd
Edition,1928, Scientific American Books, New York. REFERENCE:
01.Brown C.M., Campbell I., Priest F.G., Introduction to Bio
Technology, 1st edition, 1988, Blackwell Scientific Publications,
London.
Self Learning Course-Major FOOD SCIENCE Code: 14803428
SEMESTER IV
Addl. Credits 4
Objectives:
To understand the Nutritive values of Bio molecules, planning of
balanced diets and about preservation methods of foods and also about
food laws.
UNIT – I:
Carbohydrate – Function, Digestion and Absorption, Regulation
of Blood Sugar, Requirements.
Lipids – Chemistry, Properties, Functions, EFA, Digestion and
Absorption, deficiency, Hypercholesterolemia and coronary heart
disease.
Proteins – Digestion and Absorption, Functions, Nutritive value
of proteins, Evaluation of the nutritive value of proteins, Protein
Calorie Malnutrition in Children.
UNIT – II:
Energy units, determination of energy value of foods,
Physiological energy value of foods, Basal metalosim – Determination,
Standards, Factors affecting BMR, Specific Dynamic Action.
Effect of cooking and heat processing on the nutritive value of
foods – Vitamins, Minerals, Cereals, Legumes, Fats and Oils, Milk and
Milk Products.
UNIT – III:
Food groups and planning of balanced diets – Classification of
foods – Functional classification of food, 7 food group plan, 11 food
group plan.
Infant nutrition and infant food, modification of animal milk for
infant feeding, processed infant foods, supplementary food.
Nutrition of school children, adolescents, pregnant and lactating
mothers.
UNIT – IV:
Food Quality and Food Adulteration.
540
Sensory evaluation – Sensory characteristics of food, conducting
sensory, reasons for testing food quality, types of tests – Difference
tests, rating tests, sensitivity test, descriptive test.
Food adulteration – Definition, Types, Microbial Contamination,
Metallic Contamination, Packaging Hazards, food law and standards.
Food additive and its ill effects.
UNIT – V:
Food Preservation and Future Foods.
Methods of food preservation - by low temperature, by high
temperature, by preservatives, by high osmotic pressure, by high salt
concentration, by dehydration.
Biotechnology in food, Biofortification, Nutraceuticals, Organic
foods, Low cost nutrient supplement, space food.
TEXT BOOK:
01. Dr. M.Swaminathan, Hand Book of Food and Nutrition, 5th
Edition, 2006, Bangalore Press.
REFERENCE:
01. Srilakshmi B., Food Science, 3rd Edition, 2006, New Age
International Publisher.
Allied Biology CYTOLOGY Code: 14283321 [For Biochemistry Major Students]
SEMESTER III
4 Hrs/Week Credits 4 Objectives:
Understanding the essential principles, process of cell biology.
To know dynamic nature of the cell, its capacity of growth and
division.
To acquire informations about cells and how they functions.
UNIT – I: [9 Hrs]
Cell Structure – Prokaryotic and Eukaryotic (Plant and Animal
Cells – Structural Features – A Brief Account)
Plasma Membrane – Chemistry and Ultra Structure – Fluid
Mosaic Model, Functions to be dealt Briefly.
Protoplasm:
Chemistry and Organisation.
UNIT – II: [9 Hrs]
Membrane systems in Eukaryotes:
Endoplasmic Reticulum and Golgi Complex, Structure and
Function to be dealt Briefly.
Nucleus:
Nuclear Envelope Structure, Chromosomes – Kinds, Structure.
541
UNIT – III: [9 Hrs]
Organelles in Eukaryotes:
Plastids – Kinds, Occurrence in Plants, Chloroplast, Ultra
Structure, Functions, Mechanism of Photosynthesis – Brief Account.
Ultra Structure and Functions (Brief Account) Mitochondria,
lysosomes and Ribosomes.
UNIT – IV: [9 Hrs]
Cell Cycle – Mitosis and Meiosis, Cell Growth Normal and
Cancerous.
UNIT – V: [9 Hrs]
Histochemical Staining
a. Proteins, (Mercuric Bromophenol Blue Method)
b. Lipids and Lipoproteins – Sudan Black ‘B’ Methods
c. Carbohydrates.
TEXT BOOK:
01. Verma P.S., and Agarwal V.K., Textbook of Cytology, S.Chand and Co., New Delhi,1st edition,1995.
REFERENCES: 01.De Robertis E.D.P., F.A.Saez and De Rovertis E.M.F., Cell and
Biology,8th edition,1998,B.I. Waverly Private Limited, New Delhi,
. Allied Biology HUMAN GENETICS Code: 14283421
[Biochemistry Major Students] 4 Hrs/Week
SEMESTER IV Credits 4
Objectives:
The bio chemistry of the nucleic acid lies at the heart of genetics
molecular anatomy of cells used to analyse evolutionary relationships
and to refine evolutionary theory.
UNIT – I: [12 Hrs]
Transmission Genetics: Mendelian Inheritance – Mendels work,
method experiments observation and results. Terminology – Mendels
laws. Non allelic gene interactions. Multiple alleles – Blood group
inheritance in man.
UNIT – II: [12 Hrs]
Sex determination and differentiation: The different levels of
sexual identity, sexual development. Sex chromosomes – SRY gene
action begins sexual differentiation. The phenotype forms sex linked
recessive inheritance, sex linked dominant inheritance – Sex limited
traits, sex influenced traits, genomic imprinting.
UNIT – III: [12 Hrs]
Cytogenetics: Portrait of a chromosome, visualizing chromosome
obtaining cells for chromosome study, preparing cells for chromosome
observation. Abnormal chromosome number – Polyploidy –
542
Aneuploidy, sex chromosome aneuploidy abnormal chromosome
structure – Deletions, duplication, Inversions and Translocations.
UNIT – IV: [12 Hrs]
Population Genetics: A population view of the gene – Gene pool,
gene flow, Allele frequency and genotype frequency. Hardy – Weinberg
equilibrium – An over view. Demonstrating H-W equilibrium
applications and factors affecting H-W equilibrium.
UNIT – V: [12 Hrs]
Simple Mendelian Traits in human – modes of inheritance;
pedigree charts – symbols, lines and numbers. Twins – Types of twins.
Inborn errors of metabolism – PKU and Albinism.
TEXT BOOK:
01. Ricki Lewis, Human Genetics-Concepts and Applications, 3rd
Edition, 1999, WCB McGraw – Hill Publications.
REFERENCE:
01. Robert J.Brooker, Genetics Analysis and Principles, 1st Edition,
1999, Addision Wesley Menlo Park.
Allied Biology Lab LAB IN CYTOLOGY AND HUMAN GENETICS
[Biochemistry Major Students] 2 Hrs/Week
SEMESTER III & IV Credits 2
Code: 14283423
Objectives: To learn the methods of Preperation, observation of cellular structures.
To verify the methods of inheritance by simple Experiments.
1. Demonstration of Histochemical Staining Method.
2. Study of Mitosis – Smear method of Allium Cepa Root.
3. Study of Human Finger Print.
4. Study of Human Chromosome.
5. Survey of single mendelian traits in Man.
6. Study of Mendel’s Law.
7. Inheritance of Physical Characters in Man.
8. Verification of Hardy – Weinberg Law.
9. Pedigree Analysis.
10. Different Types of Muscles (Spotter only).
11. Aneuploidy in human sex chromosomes.
REFERENCE:
01. Peter Abram Off and Robert G.Thomson, An Experimental
Approach to Biology, 2nd Edition W.H. Freeman and Company
Sanfrancisco.
543
B.Sc BIOCHEMISTRY: Those who have joined from the
academic year 2014-15 onwards under CBCS System
EVALUATION PATTERN
Internal : 25 Marks External : 75 Marks
INTERNAL:
Test – 20 (average of the better two of the three tests conducted)
Assignment – 5
Question Paper Pattern:
INTERNAL EXTERNAL
Part – A : 6 1 = 6
(Multiple Choice)
Part – B : 2 7 = 14
(Either /Or)
Part – C : 2/3 10= 20
*40
Part – A :10 1 = 10
(Multiple Choice)
Part – B : 5 7 = 35
(Either /Or)
Part – C : 3/510 = 30
75
* Internal test mark 40 will be converted to 20.
SBE & NME
INTERNAL EXTERNAL
Part – A : 3 1 = 3
(Multiple Choice)
Part – B : 1 7 = 7
(Either /Or)
Part – C : 1/2 10= 10
20
Part – A :15 1 = 15
(Multiple Choice)
Part – B : 3/5 10 = 30
Part – C : 2/415 = 30
75
The Assignment Component of any one of the subjects (except
Non-Major Electives and other Department Papers) in the III and IV
Semesters in UG COURSES (as decided by the Head of the Department
on Rotation Basis) should be in the form of REPORT (as per the
guidelines) on the HANDS ON EXPERIENCE GAINED by the students
from their:
Part-time job (or)
Self-Employment (or)
Making of Hand made Products (or)
Survey on Marketing of goods and services (or)
Maintenance and Servicing of Equipments (or)
How things Work (or)
Working Principles of Toys/gadgets…. Models (or)
Making of working Models using some Concepts
Students should maintain a work diary which should be
monitored by the course teacher guided by a Monitoring Committee
of the concerned department.