Post on 08-Mar-2020
Jack T. Holladay, M.D., M.S.E.E., F.A.C.S.
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ADVANCED IOL POWER CALCULATIONS
Jack T. Holladay, MD, MSEE, FACS I. Formulas and Measurements
A. Variables Used to Predict ACD 1. Binkhorst 2 - 1981 - AL 2. Holladay 1 - 1988 - AL, K 3. SRK/T - 1990 - AL, K 4. Hoffer Q - 1993 - AL, K 5. Olsen - 1995 - AL, K, ACD 6. Clarke- 1996 - AL, K1, K2 ACD, LT 7. Holladay 2 - 1996 - AL, K, HWTW, REF, ACD, LT, AGE
B. Normal Values for required Measurements 1. Axial Length: mean = 23.5 mm, SD = 1.25 mm 2. Keratometry: mean = 43.81 D, SD = 1.6 D 3. Horizontal White-to-White (Corneal diameter): mean = 11.7 mm, SD = 0.46 mm 4. Preoperative Refraction: mean = plano 5. Anterior Chamber Depth (ultrasonic): mean = 3.1 mm, SD = 0.30 mm 6. Crystalline Lens Thickness (ultrasonic): mean = 4.7 mm, SD = 0.41 mm 7. Age: mean = 72, SD = 12 years
II. Axial length Measurements in Aphakic and Pseudophakic eyes A. Aphakia - 1532 M/sec B. Pseudophakia
1. PMMA - 2718 M/sec 2. Silicone - 980 M/sec 3. Acrylic- 2120 M/sec
III. Determination of corneal power following Keratorefrative Sx (PRK, LASIK, RK) A. Manual Keratometry B. Automated Keratometry C. Corneal Topography D. Calculation from pre- keratorefractive surgery K’s E. Determination from hard contact lens trial IV. Data Screening Techniques on Preoperative Measurements A. Probability of unusual measurements (one eye only) B. Probability of asymmetrical measurements (both eyes) V. IOL Calculations requiring Axial Length Measurements A. Standard Cataract Removal with IOL
1. Piggy-Back IOL’s: Use 34 D IOL posterior in bag 2. Multifocal IOL’s: Target distance plano, near for -3.00 D. 3. Toric IOL’s: IOL Cylinder to Corneal Cylinder ~ 1.46, but not exact for low (1.75) and high (1.20) power IOLs a. Optimization of Cataract Incision Location: Normal 4 locations for zero residual astigmatism b. Back calculation for surprise: 1) P.O. Refraction &, 2) P.O. Ks OR Current IOL axis
B. Cataract Removal with IOL and Silicone in Vitreous: use convexplano ~ 3 D more, for biconvex ~ from 5 - 6 D more in IOL.
Jack T. Holladay, M.D., M.S.E.E., F.A.C.S.
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VI. IOL Calculations not requiring Axial Length A. Secondary Implant for Aphakia: in sulcus or anterior chamber angle B. AC IOL in phakic patient: High myopia ( - IOL) & High hyperopia ( + IOL)
C. Secondary Piggy-Back IOL for high hyperopia (or myopia within 1 year) VII. Pediatric IOL calculations
A. Ideal Postoperative Target Refraction: plano to -1.00 D. B. Expected Myopic Shift with age: 4 D from age 2 to age 21.
VIII. Minimizing Prediction Error A. Personalizing Formula Constants (A-const, ACD or Surgeon Factor) B. Prediction Error vs. IOL Power C. Creating personalized constants for subgroups
1. Axial Length (< 22 mm or > 26 mm) 2. Keratometry (< 40 D or > 48 D) 3. Preoperative Refraction (< -4 D or > +4 D)
IX. Calculating SIRC (Surgically induced refractive change) A. From pre and post operative keratometry B. From pre and post operative refraction
X. Outcomes Analysis A. Prediction Error Analysis: Mean absolute prediction error should be < 0.50 D. B. Formula Comparisons: more predictors, better results in unusual eyes C. SIRC Results: Astigmatic Analysis D. Visual Acuity Results
1. Best corrected 2. Uncorrected
XI. Back-calculations A. For determining source of error with refractive surprise B. Comparison of back-calculated lens constant and actual lens constant
ADVANCED IOL CALCULATIONS 2016
JACK T. HOLLADAY, MD, MSEE, FACS Page 1 of 27
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AdvancedIOL Power Calculations
Jack T. Holladay, MD, MSEE, FACSClinical Professor of Ophthalmology
Baylor College of MedicineHouston, Texas, USA WWW.AAO.ORG
0
AMERICAN ACADEMY OF OPHTHALMOLOGY
Financial Disclosure I have the following financial interests or relationships to disclose:
Abbott Medical Optics: C;
AcuFocus, Inc.: C,O;
Alcon Laboratories, Inc.: C;
ArcScan: C,O;
Carl Zeiss Inc: C;
Elenza: C,O;
Oculus, Inc.: C;
Visiometrics: C,O;
Wavetec: C
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www.docholladay.com
Handouts
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Jack T. Holladay, MD, MSEE, FACS
Clinical Professor of Ophthalmology
Baylor College of Medicine
Houston, Texas
www.docholladay.com
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Vergence Formula
Theoretical Formula has not changed in 173 years
Physiologic Assumptions may be slightly different Retinal thickness
Corneal Index of Refraction8/26/2016 JTH 7
Vergence Formula
IOLAL ELP
DPostRxV
K
ELP
1336 13361336
10001000
ADVANCED IOL CALCULATIONS 2016
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E L PEffective Lens Position
Distance from corneal vertex to principal plane of thin IOL (no thickness)
Same as ACD, but avoids confusion with anatomy
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Prediction of E L P
<1980 Constant (0) 4.5
1981 Binkhorst 2 (1) AL
1988 Holladay 1 (2) AL, K
1995 Olsen (4) AL, K, ACD, LT
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Prediction of E L P
1996 Holladay 2 (7) AL, K,
ACD, LT, HWTW, REF, AGE
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Investigation International Study - 1993 34 investigators (15 U.S.)
Additional measurements are
taken 35 eyes < 21 mm
35 eyes > 26 mm
35 eyes = normal8/26/2016 JTH 15
Measurements taken forPredictors of ELP
Axial Length Average K Horizontal WTW ACD LT Pre-opRefraction Age
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HWTW Gauge
Horizontal Corneal Diameter
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IOL MASTER 500 – ZEISSVersion 7.70
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LENSTAR – HAAG-STREIT
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0
200
400
600
800
1000
Anterior Segment Size
# o
f C
ase
s
Small Normal Large
Normal Eyes
2%
96%
2%
N = 824
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0
20
40
60
80
Anterior Segment Size
# of
Cas
es
Small Normal Large
Short Eyes ( < 21 mm)
20%
80%
0%
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0
20
40
60
80
Anterior Segment Size
# of
Cas
es
Small Normal Large
Long Eyes ( > 27 mm)
0%
90%
10%
ADVANCED IOL CALCULATIONS 2016
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Normal Physiologic Values
Al: 23.5 mm + 1.25 mm
K: 43.81 D + 1.6 D
Hwtw: 11.7 mm + 0.46 mm
Ref: -0.60 D + 2.00 D
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Normal Physiologic Values
ACD: 3.1 mm + 0.30 mm
LT: 4.7 mm + 0.41 mm
Age: 72 years + 12.0 years
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Critical Data
Corneal Power
“Optical” Axial Length
Horizontal “White-to-White”(11.7) AC angle = WTW + 1.0 (12.7)
Sulcus = WTW + 1.5 (13.2)
Bag = WTW – 1.0 (10.7)
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CONCLUSION
Eye Model must include
NINE
types of eyes not only
THREE
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CONCLUSION: 9 EYES
Ant
erio
r S
egm
ent S
ize
Axial LengthShort Normal Long
Large
Normal
Small
Megalocornea Large Eye
+ axial Megalocornea Buphthalmos
hyperopia Megalocornea
+ axial myopia
axial hyperopia normal axial myopia
Small eye Microcornea
Nanophthalmia Microcornea + axial opia
(20%)
(10%)(2%)
(2%)
(80%) (96%) (90%)
(0%)
(0%)
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Relative Importance ofPredictors for ELP
Axial Length 100 Average K 76 Horizontal WTW 24 Refraction 18 ACD 8 LT 7 Age 1
ADVANCED IOL CALCULATIONS 2016
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15 20 25 30 35
-20
0
20
40
60
80
100
Axial Length (mm)
IOL
Pow
er (
D)
Small Ant. Seg.
Normal Ant. Seg.
Large Ant. Seg.
EMMETROPIC IOL POWER
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THE HOLLADAY 2 FORMULA
More Measurements
More Accuracy
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RESULTS
New Holladay 2:
Normal eye: 50% + 0.40 D
Unusual eye: 50% + 0.80 D
Previous results:
Normal eye: 50% + 0.50 D
Unusual eye: 50% + 5.00 D8/26/2016 JTH 34
FORMULA PERFORMANCE
15 20 25 300
1
2
3
4
5
6
Axial Length (mm)
Mea
n A
bsol
ute
Err
or (
D)
Holladay 1
Hoffer Q
SRK/T
Holladay 2
N = 997
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CONCLUSIONS
Prediction Errors in Short Eyes:significantly improved by more measurements
Prediction Errors in Long Eyes:due to bad Axial Lengths, B-Scan
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Myopic Staphyloma
ADVANCED IOL CALCULATIONS 2016
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Subtractfrom Ascanmeasured
Axial Length~ 0.8 mm
Zeiss - IOL Master - 2000Zaldivar-Holladay JCRS May 2000
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J Cataract Refract Surg 2011; 37:2018–2027
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Linear Regression to compensate for AVERAGE Index of Refraction in Long Eyes
Measured 36 34 mm
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Zeiss-Humphrey IOL MasterLenStar
Difficult CasesAsteroid Hyalosis (vit. debris)Extreme Length (26.5 mm)
Uses Average Index Too LongExtreme Short (< 21 mm)Pseudophakic EyesSilicone in Vitreous
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orizontal Angle & Alpha & Kappa
PCVA
< Κ
Angle Kappa on IOL Master, LenStar and penlight ~ 0.33 mm
If > 0.70 mm then concern!
●Karhanová M, Marešová K, Pluháček F, Mlčák P, Vláčil O, Sín M. Cesk Slov Oftalmol. The importance of angle kappa for centration of multifocal intraocular lenses. 2013 Jun;69(2):64-8. [Article in Czech]● G Prakash, DR Prakash, A Agarwal, DA Kumar, A Agarwal and S Jacob. Predictive factor and kappa angleanalysis for visual satisfactions in patients with multifocal IOL implantation. Eye (2011) 25, 1187–1193
ADVANCED IOL CALCULATIONS 2016
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Horizontal Angle & Alpha & Kappa
OC
PC
VA
< α
< Κ
BEST CENTRATIONOF IOL
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LENSTAR – HAAG-STREIT
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IOL MASTER 500 – ZEISSVersion 7.70
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IOL MASTER 500 – ZEISSVersion ≥ 7.10
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IOL MASTER 700 – ZEISSVersion ≥ 1.1
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Horizontal Angle & Alpha & Kappa
OC
PC
VA
< α
< Κ
BEST CENTRATIONOF IOL
ADVANCED IOL CALCULATIONS 2016
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Data ScreeningMonocular and Binocular
Using Mean and St. Dev. an exact p-value for each measurement can be calculated
Any measurement beyond two Std. Dev. from the mean should be double checked (p<0.05)
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Data ScreeningMonocular and Binocular
Monocular: AL = 19.75 mm
p = 0.001
Binocular: Kright - Kleft = 1.5 D
p = 0.0005
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Cataract Surgery …
IOL Power Calculations
Following Refractive
Surgery8/26/2016 JTH 52
Preoperative Assessment
Endothelial Cell Count
Pachymetry
Direct Ophthalmoscope @ 16”
Corneal Topography
Determining Corneal Power
IOL Calculation
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ADVANCED IOL CALCULATIONS 2016
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Corneal Power Decision Tree
SD > 0.20 D
ToPography4.5 mm Zonal K
Ref Sx, KC, PMD, … ?
ToMography4.5 mm Zonal K
Toric?
SD < 0.20 D
H2, Olsen, Barrett Formula
(7 variables)
Exact Toric CalcATR Adjustment
Keratometry Dry Eye?
Treat > 6 wks
Exact Toric Calcw Back Surface
Yes
No
Yes
No Yes
70% of cases
No
SD > 0.03 mm
SD < 0.03 mm
No dropsBlink, Blink, …
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K = 44 D
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IOL Master LenStar2.5 mm 1.7 & 2.3 mm
K = 44 D8/26/2016 JTH 58
Astigmatism Measurementfor a 44 D Cornea
Manual Keratometer 3.2 mm Diameter
IOL Master* Keratometer 2.5 mm Diameter
LenStar† Keratometer 2.35 & 1.65 mm Diameters
(Average 2.0 mm Diameter)
* Carl Zeiss Meditec AG, Goeschwitzer Str. 51-52, 07745 Jena, Deutschland
† Haag-Streit AG, Gartenstadtstrasse 10,3098 Koeniz, Switzerland
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Ring Diameteraffects Keratometry
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If SD for K’s> ± 0.20 D (> ± 0.030 mm)
Test for Dry Eye
ToPography/ToMography
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Initial Visit 6 wks after Dry Eye Rx
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If SD > ± 0.20 D (> ± 0.030 mm)
Not Dry Eye
ToPography/ToMography
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Corneal Power afterLASIK, PRK, RK
Ideally, Calculation from both surfaces …
Calculation from Prior Data Trial Hard Contact Lens Corneal Topography Automated Keratometry Manual Keratometry
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Corneal Power afterLASIK, PRK, RK
Methods listed in order of reliability
Methods 3, 4 and 5 almost always exceed true power & result in hyperopic error
Use lowest reliable value
ADVANCED IOL CALCULATIONS 2016
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Always Topography/Tomography if Correcting
Astig
To determine if REGULAR and does not change radially
Tomography can confirm if posterior astig is WTR (~ 0.22D)
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Never Perfect Bow Tie43.5 @ 105 & 41.2 @ 15
ASTIG = +2.3 @ 10544.8 @ 96 & 40.6 @ 6ASTIG = +4.2 @ 96
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ToMography: Measures Total Power andTotal Astigmatism of Lenticle
ToPography: Measures Front SurfacePower of Lenticle and then uses backradius of 0.82 of front radius forTotal Power and can ADD 0.22 DATR for Total Astigmatism
Keratometry: Measures FrontSurface Ring or annulus Power ofLenticle (nominal 2.0 to 3.2 mm for44 D cornea) then uses back radius of0.82 of front Radius for Total Power. ShouldADD 0.22 D ATR for Total Astigmatism.
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Note: 3.0 mm Mean Zonal Power = 43.00 D3.2 mm Sim K = 43.75 DNever use Sim K’s … same as keratometer
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4 mm OZ with 6 cuts ~~ - 4.00 D
ADVANCED IOL CALCULATIONS 2016
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3 mm pinhole
Rigid Contact Lens
Trial Frame
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1. Calculation from Prior Data(Pre K & Δ MR known)
Pre KR Mean K = 44.00 D
Change in SEQ Ref = -4.50 D
Calc Mean K = 39.50 D
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2. Calculation from Prior Data(Post Std. K’s & Δ MR only)
Post Mean K = 40.58 D
Change in SEQ Ref = -4.50 D
STD K’s: -0.24 * SEQ = -1.08
Calc Mean K = 39.50 D
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3. Calculation from Prior Data(Post Ctr Top Power & Δ MR only)
Post Mean K = 40.27 D
Change in SEQ Ref = -4.50 D
Ctr Top: -0.15 * SEQ = -0.77
Calc Mean K = 39.50 D8/26/2016 JTH 81
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4. Trial Hard Contact Lens(Rigid Contact lens only)
Plano HCL Base Curve = 41.50 D
SEQ Ref without CL = +0.50 D
SEQ Ref with CL = -1.00 D
Front K = 41.50 - 1.50 = 40.00 D
40.00 D – 10% (4.50) = 39.50 D
Mean K = 39.50 D 8/26/2016 JTH 83
Post-operative
Initial Hyperopic Shift
Long Term Hyperopic Drift
ATR Astigmatism Drift
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If Posterior to Anterior Radius Ratio ?
ToMography
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Accuracy of EKRPrior
Sx
STD 4.5
(D)LASIK 0.56
RK 0.94
Holladay JT, Hill WE, Steinmueller A. Corneal Power Measurements Using Scheimpfl ug Imaging in Eyes With Prior Corneal Refractive Surgery. J Refractive Surgery 2009:25:862-868. (October 2009 Issue of J Refr Surgery)
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J Cataract Refract Surg Feb 2015; 41:339–347
8/26/2016 JTH 101Holladay Report Equivalent Keratometric Power
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Asymmetric Bowtie Early Keratoconus Post LASIK
Normal LASIK RK
41 to 44 D3 D Range
36 to 41 D5 D Range
32 to 45 D13 D Range
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Summary Optimal Zone LASIK: 4.5 mm RK: 5.0 mm Customize for small/large pupils
Accuracy LASIK: 0.56 D RK: 0.94 D
Error on MYOPIC side
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IOL CALCS in Keratoconus
Corneal is Bifocal
Patient does not look through cone for distance (may use at 10 cm as magnifier
Look at Power Distribution
Use Paracentral Power
(65% Mean Power) 8/26/2016 JTH 111
Keratoconus #1
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Keratoconus #1
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Keratoconus #1Keratoconus #1
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`Keratoconus #1
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Keratoconus Calculation #1OS
Used Km = 46.5 D => +1.00 D
Should have used 65% Mean 45.5 D => plano
should have targeted -0.50 D
(-0.50 always better than +0.50)
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IOL Calcs Using Axial Length
Cataract or Clear Lens Removal Primary Piggy-Back IOL’s
Multifocal IOL’s
Toric IOL’s
Silicone in Vitreous Compartment
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Axial Length Measurements
Phakia AL1555
Aphakia AL1532
Pseudophakia PMMA AL1532 + 0.4
Silicone AL1532 - 0.6
Acrylic AL1532 + 0.2
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Primary Piggy-Back IOL’s
Current Formulas are very inaccurate
ELP underestimated due to AL
Back lens displaced posteriorly
Severe hyperopic errors (+5 D) 8/26/2016 JTH 127
Primary PIGGY-BACKINTRAOCULAR LENSES
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Polypseudophakia
Up to 4 IOL’s
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PIGGY-BACKINTRAOCULAR LENSES
J.T. Holladay James P. Gills
Jane Leidlein Myra Cherchio
“Achieving Emmetropia In Extremely Short Eyes With Two Piggy-Back Posterior
Chamber Intraocular Lenses.”
Ophthalmology Journal. Vol. 103.
July 1996 Blue Journal”
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Primary Piggy-BackComplications
AcrylicInterlenticular membrane3 to 5 D hyperopic shift @ 3 yr
SiliconeInterlenticular membraneFlat Spot
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Minimizing Prediction Error
Holladay 2 Formula
Personalize Constant
Prediction Error vs. IOL power
Constants for Sub-groups Axial Length, K’s and Refraction
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Toric IOL’s
Current Formulas do not work because calculate different ELP for steep and flat meridian
Predicted ELP must be the same for each meridian --only one IOL position
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Toric IOL’s
Calculate IOL power for steep and flat meridian using same ELP
Difference in IOL powers is the toricity necessary to completely correct corneal astigmatism
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Ideal Toric IOL Calcs
Accurate corneal power and astigmatism … repeat is SD > 0.020 D (0.030 mm)
Exact Toric Calculator (not a constant ratio of corneal astigmatism to toricity (1.46)
Proper Surgically Induced Astigmatism (SIA) for incision location and magnitude and axis of PreOp astigmatism … must account for ATR over 3 to 6 months PostOp
Results will be greater than 80% within 0.50 D
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Toric IOL’s Always choose toricity to
undercorrect cornealastigmatism – WRONG!
LEAVE MIN RESIDUAL CYL!
Eg: Steep calc yields 24.0 DFlat calc yields 27.0 D
Ideal Toricity is 3.0 D
(Use 24.0 D with < 3.0 D of toricity)
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Never Perfect Bow Tie43.5 @ 105 & 41.2 @ 15
ASTIG = +2.3 @ 10544.8 @ 96 & 40.6 @ 6ASTIG = +4.2 @ 96
TORIC IOL Calculations
Commercial Calculators use a constant ratio (1.46) for the corneal cylinder to the IOL cylinder
Exact Calculation depends on IOL SEQ Power and ELP… to correct 2D of corneal astigmatism
10 D IOL => 3.5 D Cylinder 22 D IOL => 2.9 D Cylinder 34 D IOL => 2.4 D Cylinder
A 1.1 D difference from 10 D to 34 D!
Toric CalculatorsExact Approximate
• Holladay On-line
• AMO Express On-line
• Holladay IOLConsult
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• Alcon On-line
• B & L On-line
• Barrett On-line
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Dioptric Error vs. Angular Errorfor a 1.00 D of astigmatism
Angle Error ( ) Dioptric Error (D)
Dioptric Error = 2 * Cyl * sin (angular error)
% Error0° 0.00 0%
15° 0.52 52%
30° 1.00 100%
45° 1.41 141%
60° 1.73 173%
75° 1.93 193%
90° 2.00 200%
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Abulafia A, Hill WE, Franchina M, Barrett GD. Comparison of Methods to PredictResidual Astigmatism After IOL Implantation. J Refract Surg. 2015;31:699-706
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Abulafia A, Hill WE, Franchina M, Barrett GD. Comparison of Methods to PredictResidual Astigmatism After IOL Implantation. J Refract Surg. 2015;31:699-706
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Abulafia A, Koch DD, Wang L, Hill WE, Franchina M, Assia EI, Franchina M, Barrett GD. New regression formula for toric IOL calculations. J Cat Ref Surg. 2016; 42:663-671 Surgically Induced Astig (SIA)
• Critical to use correct value
• Not ~0.35 D WTR for small (2.5 mm), near-clear temporal incision
• Better to use Zero SIA and Baylor Nomogram– ↓ WTR (steep 90) by ONE Toric Size (T4 T3)
– ↑ ATR (steep 180) by ONE Toric Size (T3 T4)
– No change in Oblique
• Equivalent to ADDING ~ 0.51 D ATR as SIA
Wang/Koch Recommendation
• WTR: Subtract 0.6 D from measured
• ATR: Add 0.2 D to measured
• Oblique: No change
Equivalent to:
SIA = 0.2 + 0.4 sin2(Steep axis of astigmatism)
0 = 0.2@90 45 = 0.4@90 90 = 0.6@90
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SIASteep Axis ( ) Magnitude (D) Axis of Flattening ( )
0 0.20 90
10 0.21 90
20 0.25 90
30 0.30 90
40 0.37 90
45 0.40 90
50 0.43 90
60 0.50 90
70 0.55 90
80 0.59 90
90 0.60 90 164
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Additional Factors (Wang/Koch)
Posterior cornea has ~ 0.25 D WTR
WTR decays ~ 0.50 D WTR
ATR decays ~ 0.00 D ATR
Result: ↓ K WTR by 0.75 D
↑ K ATR by 0.25 D
x
ADVANCED IOL CALCULATIONS 2016
JACK T. HOLLADAY, MD, MSEE, FACS Page 22 of 27
x
8/26/2016 JTH 168
Right Eye Left Eye
ATR WTR
8/26/2016 Jack T. Holladay, M.D. 169
www.hicsoap.com CALCULATORS TAB
8/26/2016 JTH 174
Post Op Toric Calculators
Holladay IOL Consultant www.hicsoap.com
Berdahl & Hardten Toric IOL Calculator www.astigmatismfix.com
8/26/2016 JTH 175
Two Sources of Error
IOL misaligned (wrong axis)
IOL Toricity wrong (over/under)
Or
Both
8/26/2016 JTH 176
ADVANCED IOL CALCULATIONS 2016
JACK T. HOLLADAY, MD, MSEE, FACS Page 23 of 27
8/26/2016 JTH 177
PREOP 6 D Toric IOLLEFT
8/26/2016 JTH 178
PREOP 6 D Toric IOL -- ODLEFT
8/26/2016 JTH 179
PREOP 6 D Toric IOL -- OSLEFT
8/26/2016 JTH 181
Mean Dev = -0.72 D
8/26/2016 JTH 182
Silicone in Vitreous Cavity
Use Convexo-Plano IOL to minimize effect of Silicone(add 3 D to calculated IOL)
If Biconvex IOL(add 6 D to calculated IOL)
When Silicone removed -- 2 to 5 D of induced myopia
8/26/2016 JTH 183
IOL Calculations
using a
Refractive Formula
(ignore axial length)
ADVANCED IOL CALCULATIONS 2016
JACK T. HOLLADAY, MD, MSEE, FACS Page 24 of 27
8/26/2016 JTH 184
IOL Calculation without AL
Secondary AC or PC IOL for Aphakia
Secondary Piggy-Back AC or PC IOL for Pseudophakia
Primary AC IOL in Phakia
8/26/2016 JTH 185
REFRACTION FORMULA
IOL
PreRxV
KELP
DPostRxV
KELP
13361336
10001000
13361336
10001000
8/26/2016 JTH 186
Secondary Piggy-Back IOL’sIndications
Intolerable Pseudophakic Refractive Error
8/26/2016 JTH 187
Refractive Surprises
Previous RK, PRK, LASIK
Bad axial length - short/long
Mislabeled IOL
Axially displaced
Misc.
8/26/2016 JTH 188
Secondary Piggy-Back CalcAdvantages over Exchange
Mislabeled IOL irrelevant
Less risk to capsule or zonules
Mismeasured AL irrelevant
No AP shift of existing IOL
Fewer unknown variables8/26/2016 JTH 189
ADVANCED IOL CALCULATIONS 2016
JACK T. HOLLADAY, MD, MSEE, FACS Page 25 of 27
8/26/2016 JTH 190 8/26/2016 JTH 203
8/26/2016 JTH 204
IOL Power Calcs for Phakic IOLs
(2º Piggy-Back & IOL Exchange after
Refractive Surprise)
Jack T. Holladay, MD, MSEE, FACSClinical Professor of Ophthalmology
Baylor College of MedicineHouston, Tx 8/26/2016 JTH 205
Phakic IOL’s
Compete with corneal refractiveprocedures for high myopiaand med & high hyperopia
ACL, ICL or Iris Clip ?
8/26/2016 JTH 206 8/26/2016 JTH 207
Phakic IOL’s(Secondary Piggy Back IOL’s)
Refraction
Formula
ADVANCED IOL CALCULATIONS 2016
JACK T. HOLLADAY, MD, MSEE, FACS Page 26 of 27
8/26/2016 JTH 209
Phakic IOL CalculationInput Variables
Refraction and Vertex
Keratometry
Desired Refraction
Predict ELP (ACD)Effective Lens Position
8/26/2016 JTH 210
REFRACTION FORMULA
IOL
PreRxV
KELP
DPostRxV
KELP
13361336
10001000
13361336
10001000
Holladay, J.T.: "Refractive Power Calculations for IntraocularLenses in the Phakic Eye." American Journal of Ophthalmology.
Volume 116:63-66, July 1993.
8/26/2016 JTH 211
Phakic IOL CalculationInput Variables
Refraction and Vertex
Soft Contact Lens @ Vtx = 0
w Small Over-Refraction (< 2 D)is most accurate.
8/26/2016 JTH 212
Effective Lens Position (ELP)OLD ACD
Verisye Avg ELP = 4.27 mm
AACD (20 y/o) = 3.60 mm
AACD + 0.67 mm = ELPx
8/26/2016 JTH 213
Effective Lens Position (ELP)OLD ACD
Visian ICL Avg ELP = 4.00 mm
AACD (20 y/o) = 3.60 mm
AACD + 0.40 mm = ELPx
8/26/2016 JTH 214
Effective Lens Position (ELP)OLD ACD
Visian ICL Avg ELP = 4.00 mm
ADVANCED IOL CALCULATIONS 2016
JACK T. HOLLADAY, MD, MSEE, FACS Page 27 of 27
8/26/2016 JTH 215
Phakic IOL Calculations
+ IOL’s to Specs ~ 1.5 to 1
- IOL’s to Specs ~ 1.0 to 1
Approximation only
8/26/2016 JTH 220
8/26/2016 JTH 222 • • • • The International Society of Refractive Surgery • • • •
April 23,2002Sydney
Thank you !
WWW.AAO.ORGAMERICAN ACADEMY OF OPHTHALMOLOGY
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