¨ à QØüseika/H24/_userdata/...Figure 10-15 Molecular Biology of the Cell (© Garland Science...

Post on 10-Jun-2020

1 views 0 download

Transcript of ¨ à QØüseika/H24/_userdata/...Figure 10-15 Molecular Biology of the Cell (© Garland Science...

!m !m

!m = , nm

nm

nm !m,

X mm , mm,

Figure 10-3 Molecular Biology of the Cell (© Garland Science 2008)

Table 10-1 Molecular Biology of the Cell (© Garland Science 2008)

Figure 10-3 Molecular Biology of the Cell (© Garland Science 2008)

!

!3 (n-3) !6 (n-6)

!3 (n-3) !6 (n-6)

metabolism

metabolism

digestion

absorption

catabolism

anabolism

metabolism

digestion absorption

catabolism

anabolism

Figure 10-15 Molecular Biology of the Cell (© Garland Science 2008)

Figure 13-9a (part 1 of 2) Essential Cell Biology (© Garland Science 2010)

VLDL TG LPL

TG

TG LPL

(LPL) (TG)

(CM) (VLDL)TG

LPL TG CM-TGVLDL-TG

I (LPL ) IV VI

II LPL

LPL

!

" CoA!

!

" CoA!

CoA "

CoA

CoA

CoA

R

CoA

CoA

CoA

CoA

CoA

ATPAMP

Familial Hypercholesterolemia [ ]

1[ ]

50 500 1100 1

[ ]30 50

301

20

[ ]1d 300 600mg

600mg 170mg

[ ]130mg

1 20 25

1 200mg

HDL

0.5-1.5 g

0.3-0.5 g

"

"

LDL

LDL " LDL "

LDL

LCAT ACAT

LCAT ACAT

LCAT

LCAT

+

+

ACAT CoA

ACAT

CoA +

CoA +

LDL

SREBP

. LDL LDL

.

SREBP

HMG-CoA LDL

!

!

!