Quick Lesson on dN/dS Neutral Selection Codon Degeneracy Synonymous vs. Non-synonymous dN/dS ratios Why Selection? The Problem.
PNAS-2015-Lee-1507071112
Time-dependent rates of molecular evolution Evidence and causes Simon Ho School of Biological Sciences.
PAML (codeml) the basic model
Adaptive evolution of genes underlying schizophrenia Bernard Crespi, Kyle Summers, Steve Dorus
Other ways to detect positive selection Selective sweeps -> fewer alleles present in population
Quick Lesson on dN/dS
… and what about positive Darwinian selection?
Time-dependent rates of molecular evolution Evidence and causes