CS262 Lecture 9, Win07, Batzoglou History of WGA 1982: -virus, 48,502 bp 1995: h-influenzae, 1 Mbp 2000: fly, 100 Mbp 2001 – present human (3Gbp), mouse.
Evolution at the DNA level …ACGGTGCAGTTACCA… …AC----CAGTCCACCA… Mutation SEQUENCE EDITS REARRANGEMENTS Deletion Inversion Translocation Duplication.
CS273a Lecture 8, Win07, Batzoglou Evolution at the DNA level …ACGGTGCAGTTACCA… …AC----CAGTCCACCA… Mutation SEQUENCE EDITS REARRANGEMENTS Deletion Inversion.
Some new sequencing technologies. Molecular Inversion Probes.
CS262 Lecture 9, Win07, Batzoglou Phylogeny Tree Reconstruction 1 4 3 2 5 1 4 2 3 5.
CS273a Lecture 10, Aut 08, Batzoglou Multiple Sequence Alignment.
CS273a Lecture 9/10, Aut 10, Batzoglou Multiple Sequence Alignment.
Short Primer on Comparative Genomics Today: Special guest lecture 12pm, Alway M108 Comparative genomics of animals and plants Adam Siepel Assistant Professor.
