Chapter 12 Topics Chapter 12 Topics Models of Replication Prokaryotic and Eukaryotic Replication Models of Recombination: read pp 339-342.
Learning goals: Students will understand that 1) molecular mechanisms that preserve the fidelity of the genetic sequence have been favored by natural selection,
Repair of DNA and XP Errol C. Friedberg (2003) DNA damage and repair. Nature 421: 436-440.
Lecture 15: DNA Organization, Replication and Repair Reading Assignment: Chapter 38, pgs. 412-434; Harper’s Biochemistry (25 th edition). Objective: To.
The Mutability and Repair of DNA. 1. Switch of one base for another: purine pyrimidine (transition) (transversion) 2. insertion or deletion of a nucleotide.
Microbial Genetics (Micr340) Lecture 14 DNA Repair and Mutagenesis.
Definitions: ★ replication errors ★ spontaneous DNA damage ★ DNA mutations ★ double-strand break (DSB) repair pathway.
