Genetic code tutorial sheets
Trinucleotide repeat sequences (TRS) - dynamic mutations - the number of repeats tends to increase in size over generations. Several factors contribute.
Mechanism of the genetic instability of the TRS during replication.
Principles of Biochemistry Fourth Edition Chapter 20 DNA Replication, Repair, and Recombination Copyright © 2006 Pearson Prentice Hall, Inc. Horton Moran.
Genome Res. 2008 18: 1011-1019
