Brugada Syndrome
WT (0.3 µg)WT (0.15 µg)WT+L325RL325R * * Using site directed mutagenesis, we introduced the BrS mutations SCN5A-L325R and SCN5A-L567Q, and the SCN5A-H558R.
Sudden Cardiac Death (SCD). SCD is natural death from cardiac causes, heralded by abrupt loss of consciousness within 1 hour of the onset of an acute.
Antiarrhythmic Drugs. Arrhythmia Heart condition where disturbances in Pacemaker impulse formation Pacemaker impulse formation Contraction impulse conduction.
Antiarrhythmic Drugs
Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia
WT (0.3 µg)
