13 Gene Regulation by Antisense Transcription
ASSIGNING GENE FUNCTION BY EXPERIMENTAL ANALYSIS 1.Gene inactivation (loss-of-function) - mutate gene (“knock-out”) and observe change in phenotype (i)Deletion.
Nucleic Acids as Therapeutic Agents. Many human disorders often results from the overproduction of a normal protein. Single stranded oligonucleotides.
Selfish DNA
ASSIGNING GENE FUNCTION BY EXPERIMENTAL ANALYSIS
Selfish DNA Honors Genetics. DNA – Genes and the Rest GGenic ( Gene containing portion of DNA) - GGenes are viewed as “ORFS” – Open Reading Frames.
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