Loss of the LAT Adaptor Converts Antigen-Responsive T Cells into Pathogenic Effectors that Function Independently of the T Cell Receptor Michael Mingueneau,
T cell Development. Basic Principles of T Cell Development Each cell randomly rearranges a specific TCR. The presence of the pMHC epitope, stage of development.
In unimmunized mice: 1 in 26,300 spleen B cells could make anti-SRC IgM no detectable (
