Transitioning to Symyx NotebookTransitioning to Symyx Notebook by AccelrysFrom other Electronic Lab Notebooks (ELNs)
Transition to a Higher‐value ELN
Enterprise ELN• Single ELN configurable for multiple scientificSingle ELN configurable for multiple scientific domains for collaborative productivity
Domain specific ELNDomain‐specific ELN• Focused on productivity for specific scientists
Paper‐on‐glass ELN• Simple electronic replacement for paper notebooks
“Four Top‐10 Pharma have expressed interest in switching their existinginterest in switching their existing
chemistry ELNs.”
Why Transition to Accelrys? – Strategic
Single ELN for the Enterprise
Providing global organizations with an enterprise ELN that: y
Design
with an enterprise ELN that:
•Enhances scientific workflow
Collaborate & Make InferencesDistribute
& Share Results
Search & Find Data
Identify New
Opportunity
uality by
•Enhances scientific workflow, experiment, and process optimization
Collaborate & Make InferencesDistribute
& Share Results
Search & Find Data
Identify New
Opportunity
Qu
• Enables improved insight and management of complex scientific data
•Enables compliance with standards and regulatory processes and controls
Accelrys ELN: Built on Solid VisionThe Four Pillars of Scientific Enterprise R&D
Collaborate & Make
Inferences
Identify New Opportunity Search &
Find DataDistribute &Share Results Find Data
Analyze DataGenerate Reports
Share Results
Plan/Design
Reformat & Store Results in Database
Make Decision
Modeling and Workflow
ExperimentSetup Lab
& EquipmentRun
Experiment
Capture & Process Results
Modeling and Simulation
Data Management & Informatics
Enterprise Lab Management
Definition and Capture
& Informatics
Accelrys ELN: Enabled By Unique Platform Enterprise R&D Architecture
Workflow Definitiond li d Si l i Data Management 3rd Party Partner
Scientists R&D ManagerLab Manager
VP, R&D Head of IT &Informatics
ManufacturingPlant Workers
Enterprise Lab Management Workflow Definitionand Capture
Modeling and Simulation Data Managementand Informatics
3rd Party, Partner & ISV Apps
Discovery Studio
Materials Studio
Isentris Registration Pipeline PilotLEA ELN Web
Pipeline Pilot™
Ch i tCh i tORACLEORACLE Bi lBi lMaterial AnalyticalBiologyChemistry DDDD ChemistryChemistryORACLEORACLE
OtherOther33rdrd Party Party VendorsVendorsLIMSLIMS
BiologyBiologyMaterial Science
Analytical Instruments
BiologyChemistry DocsDocsDocsDocs
VendorsVendors
Text & Image Analytics
Statistics &Analytics
Reporting 3rd Party and ISV
Laboratory Ops
Symyx Notebook by Accelrys: Enterprise ELN
Synthetic
Expand access to institutional knowledge and data assets enabling b d i i Synthetic
& ParallelChemistry
Formulation
better decisions
Scientists save time Process Chemistry
Sc e t sts sa e t ecreating and reusingscientific knowledge
Target Id &Validationdi i l
IP protection and document workflow
ValidationMedicinal Chemistry Analytical
Chemistry Lowers costs by integrating lab operations and application
PharmacologyBiologicsconsolidation
Partnerships to build best of breed Partnerships to build best of breed solutions for your lab
Why Transition to Accelrys? – Tactical
• Highly‐rated customer support and consulting servicesservices
• Proven partnerships – with customers and third‐party vendors
• Industry leading chemistry and data access• Industry‐leading chemistry and data access solutions
• Information accessibility, world class chemical search and re‐use promoting internal and external collaborationexternal collaboration
• Configurability and extensibility enable rapidConfigurability and extensibility enable rapid startup
Reactions from Multiple Chemical Domains
View both conceptual and proven pathways from the
ELN datasource
Find the best and most scalable pathway with
di i l &medicinal & process chemistry and literature in a
single view
Generate synthetic pathways for compounds and view relevant data for
creating a planAccess to reactions inAccess to reactions in a non‐Accelrys ELN
Now: Accelrys Pipeline Pilot and ELN provide rapid, scalable workflows
Rapid application extensions
Library of re‐usable scientific productivity components Symyx Notebook by Accelrys
Pipeline Pilot client Custom Pipeline Pilot Protocols
Pipeline Pilot Collections
D iDesign DistributePublish
Accelrys Framework for Transitioning ELNs
E il h b d
Access multiple ELN repositories via ONE user interface
Easily search, browse and view experiments from multiple ELN repositories
Import legacy data to create NEW experiments in
the Accelrys ELN
Symyx Notebook
Process Notebook
V i 5 4
Formulations Notebook
Discovery Notebook
3rd Party ELN
Version 6.5 Version 5.4Version 5.6
Version 5.4Version 5.6
Version 4.1
The Enabling Technology: Symyx Notebook Browser web services
Transition Strategy
Protect IP – Keep signed experiments unaltered in existing third party ELN database repositorythird‐party ELN database repository.
E ti d C fi S N t b kEnsure continued access – Configure Symyx Notebook Browser web services to translate third‐party ELN data into Accelrys ELN format so it can be easily searched and viewed.
Re‐use legacy IP – The web services convert legacy data at runtime so scientists can clone experiments from the third‐runtime so scientists can clone experiments from the thirdparty ELN into Symyx Notebook by Accelrys.
Keep your scientists in touch with their experiments.
11
Recommended Transition Phases
Phase 1 – Deploy Symyx Notebook by Accelrys to new groups
Symyx Notebook by AccelrysThird‐party ELN
d/Read/WriteExperimentsRead/Write
Experiments
Thi d tSymyx
Third‐party ELN
Notebook
Recommended Transition Phases
Phase 2 – Implement hybrid access with staged transitions to Symyx Notebook by Accelrys.
Symyx Notebook by AccelrysNotebook Explorer
Symyx Notebook by AccelrysExperiment Editor Third‐party ELN
Open
Clone
Search andRead/WriteExperiments
Search and Browse
ExperimentsRead/WriteExperiments
Third‐party ELN
Symyx Notebook
Recommended Transition Phases
Phase 3‐ Access data from multiple ELNs through one UI—Symyx Notebook by Accelrysy y y y
O
Symyx Notebook by Accelrys Notebook Explorer
Symyx Notebook by AccelrysExperiment Editor
OpenClone
Search and B Read/Write
Experiments
BrowseExperiments
Thi d t SymyxPreserveThird‐party
ELN
Symyx Notebook
Legacy IP
How IT WorksMapping the Legacy Data Model to Accelrys formatExample Conversion – Accelrys Services maps data from a third‐party ELN into Accelrys format using Accelrys web services
3rd Party ELN Symyx Notebook by Accelrys
Background Form (Form Section)Background
Background Form (Form Section)
Background Description (Text Section)
MaterialsMaterialsSynthetic Chemistry Section (Materials Section)Material Amounts
ProductsProducts
Reaction Scheme Reaction Scheme Section
Procedure Procedure (Text Section)
Results and Conclusions (Sketch only) Results and Conclusions (Text Section)
Embedded Reports (Sketch only) Embedded Reports (File Section)
How IT WorksRead and Re‐use Legacy Data in Symyx Notebook by Accelrys
1 2 3
Clone legacy experiments into Accelrys format
1 2 3
Select Target Experiment from external repository
Accelrys Web Service Extracts and Converts
Accelrys ELN Reads and Inserts Data into p y
Data to XML Format Appropriate Sections
Data Sources
Select ‘Create New From…’ Accelrys Services configures Structures/Reactionsthe web service to translate data from 3rd party ELN to Accelrys format
StoichiometryMethods/SOPsEmbedded files(pdf/xls/doc/images)
How IT WorksSymyx Notebook Browser web application
• Aids while transitioning users to the Accelrys ELNView legacy and new ELN experiments in a web browser
Aids while transitioning users to the Accelrys ELN• Enables third‐party ELN users to easily view data in all mapped repositories• Scientists can view metadata, materials, and the reaction in the experiment
record without opening it• PDF report of the experiment is available on‐line• Read only access• Read‐only access
How IT WorksSymyx Notebook Browser web application
• Search criteria include dmetadata, structure,
and reaction.
• Scientists can restrict searches to specificsearches to specific, mapped ELN repositories.p
• Chemistry integrated y gfor structure/reaction drawing.
How IT WorksTransition completed
Scientists access mapped legacy ELN repositories via SymyxNotebook by Accelrysy y
Experiment Metadata
Experiment pMaterials
View Reactions
View PDF of ExperimentExperiment
Making the Transition: RecommendationsRead the white paper for technical details
Contact your Account Manager or Accelrys Services to scope the project:
• Assess your current ELN deployment and business issues/needsand business issues/needs
• Present recommendations on transition strategy, cost, and risk assessment
• Mutually agree with you on a transition• Mutually agree with you on a transition and roll‐out strategy
• Support your transition!20
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