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Skin Pigmentation
Melanin in the Melanocyte Cells
Eumelanin Black/Brown Pigment
Pheomelanin Red/Yellow Pigment
Response to UV Radiation
Pigmented Cells
Resistant to amage !y Sun
Protected "rom Melanin #ntio$idants
Unpigmented Cells
Sensiti%e to Sunlight amage
Protected !y &lutathione/Selenomethionine
#ntio$idants
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EP'&ME()#)'*( Properties o+
&lutathione/Selenium
, Protect Skin +rom UV Radiation which generate +ree
radicals that cause skin damage and hyperpigmentation
, &S- redirects synthesis to the light .Pheomelanin instead
o+ the dark .Eumelanin
, 'nhi!its en0yme tyrosinase that synthesi0es dark melanins
, Skin Cell1s !ecome more resistant to UV e$posure
.Brigarti2 3445
.Burke2 6778
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Skin Brightening
)hione Comple$9 lo0enges with:
&lutathione ; Selenomethionine
Plus #ntio$idant Vitamins C ; E
#nd the &lutathione epigmenting En0ymes
# complement to the Skin Brightening Products
"ree Radical Sca%enging "unctions to Reduce UV
Radiation to the Skin
<orks "rom <ithin )o )he Skin=
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Melasma
Blotchy -yper>pigmentation o+ "ace
#ssociated with Pregnancy
)opical )herapy
-ydro?uinone2 Retinoic #cid
)hione Comple$9
*ral )herapy with &lutathione/Selenium
Reduces UV Radiation 'mpact on #++ected Skin
'nduces &lutathione En0ymes
Promotes Synthesis o+ Clear Melanin
'nhi!its )yrosinase En0yme that Makes ark Melanin
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)he #ging Skin
Chrono>aging Sagging Skin
Photo>aging
<rinkles and Pigmented @esions Ultra%iolet Radiation
#cute: Sun!urn
Chronic: *$idati%e amage
Pre>malignant @esions.Aeratosis2 Moles
MalignancyS?uamous/Basal Cells
Malignant Melanoma
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'n+luence o+ &lutathione @e%els in
Melanin Synthesis
Pathways to Melanin Synthesis
-igh &S- @ow &S-
Eumelanin Eumelanin
.ark Pigment .ark Pigment
Conclusion:
-igh &S- le%els in+luence pathway toward the production o+ greateramounts o+ clear pigment .Pheomelanin in skin cells
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