isis-innovation.com
Knowledge Based Economy
• Every country in the world wishes to develop the Knowledge Based
Economy.
• The question is asked: • Where is the Knowledge?
• And the answer in part is inside the universities, and research institutes, and hospitals.
• And the question then becomes: • How do we transfer the knowledge out from the research base into
industry to create innovation?
isis-innovation.com
Making Connections & Doing Business
University entrepreneurial
culture
Industry, Business & Professional environment
University technology transfer resource
isis-innovation.com
Chalk and Cheese
• Universities and Businesses are very different• A university is not trying to be like a company• A company is not trying to be like a university • Why should Universities want to engage with Businesses?• Why should Business want to engage with University?
isis-innovation.com
University & Business Interactions
• Educated workforce
• Advisory Boards
• Lectures
• Exchanges
• Collaborative Research
• Contract Research
• Donations
• Consulting
• Licensing technology
• Spin-out company formation
• Entrepreneurship
isis-innovation.com
Oxford University
• Oxford University is the oldest university in the English-speaking world (founded c.1188)
• A leader in learning, teaching and research
• 26 British Prime Ministers educated at Oxford
• Including current Prime Minister David Cameron
• Royal Society founded from Oxford in 1640
• 47 Nobel prize winners
isis-innovation.com
Isis Innovation Ltd
Oxford Technology TransferIP, Patents, Licences, Spin-outs, Material Sales, Outcome Questionnaires, Seed Funds, Isis Angels Network, Isis Software Incubator, Oxford University Hospitals NHS Trust
Oxford ExpertiseConsulting, Services
@isisinnovation
A profitable company 100% owned by the University of Oxford
Isis Consulting Business Technology Transfer and Innovation Management
isis-innovation.com
Isis Innovation, year-ending March 2013
0
3
6
9
12
2001 2004 2007 2010 2013
0102030405060708090
2001 2004 2007 2010 2013
0.0
1.0
2.0
3.0
4.0
5.0
6.0
2001 2004 2007 2010 2013
SubventionReturn
0
2
4
6
8
10
12
2000 2003 2006 2009 2012
Start-UpsSpin-Outs
isis-innovation.com
Isis Innovation, year-ending March 2013
0
20
40
60
80
100
120
2001 2004 2007 2010 2013
0
20
40
60
80
100
120
2001 2004 2007 2010 20130
50
100
150
200
250
300
350
2003 2006 2009 2012
100
150
200
250
300
350
400
2006 2007 2008 2009 2010 2011 2012 2013
isis-innovation.com
Technology Transfer Group (38) Linda Naylor
Isis Innovation TeamOxford University Consulting(7)
Andrew GoffProject Managers
Susan ClarkGurinder PunnDr Josef WalkerKerry AntcliffeAdministrators
Magda BezdekovaSelina Woodcock
Dr Adam Stoten
Dr Carolyn PorterDr Alex Marshall
Dr Christine WhyteDr Ruth Barrett
Dr Richard ReschenDr Louis Pymar
Dr Paul AshleyDr Angela Calvert
Andy SelfDr Sarah Deakin
Dr Matthew CarpenterDr Nikolaos Chalkias
Dr Brijesh Roy
Medical SciencesDr Linda Maxwell
Evert Geurtsen
Rakesh RoshanDr Jon Carr
Dr Bharti RanavayaDr Andy RobertsonDr Andrew Bowen
Dr Richard HollidayChim Chu
Dr Fred KempDr Mark Gostock
Dr Weng Sie Wong
Team Leader VacancyDr David Churchman
Dr Jamie FergusonRoy Azoulay
Dr Manjari Chandran-Ramesh
Staff & Associates: 87 MBAs: 14 PhDs: 40
Managing DirectorTom Hockaday
Business Support (18)
Central AdministrationJenny BaileyPhilip Priest
Nissar MohammedRicky AllainIsabel Lavis
HRCarolyn Hall
Alex AllanViv Parry
MarketingSimon GrayRenate Krelle
Dr Chandra RamanujanDr Fiona StoryBarney Cullum
FinanceJaneen WilsonGemma Allnutt
Amanda Thornton
LegalParesh Jasani
Technology Transfer Teams
Isis Enterprise (24)Consultants
Dr David Baghurst (Hong Kong) Ya-hsin Shen (Hong Kong)
Dr Jimmy Wang (Hong Kong) Dr Wenming JiRenchen Liu
Kenji Aiba (AC-Japan)Xiaowei Hu (AC-China)Dr Costas Chryssou
Dr Sarah BondDr Andrew BarberDr Mireya McKee
Dr Steve Cleverley Elena Andonova
Dr Alexandra BushDr Sarah Macnaughton
Gaurav MisraBruno Reynolds
Eva Baltar, Manuel Fuertes (AC-Spain)Dr Tim Hart (AC-UK)
Dr Chris MoodyDr Salvador Venegas (AC-Mexico)
OperationsShelagh Harrison, Chloë Cairns
Operations Patent & Licence Dr Mairi Gibbs Steven Bayliss
Zuzana Weberova Seed Investment Kate Spanchak
Andrea Alunni
Administration Kristin
Hayes
isis-innovation.com
Academic axis£ -> Research
3D – Spin-out
2D – Licence, Consulting
Isis Innovation StaffActing as Multi-dimensional Intermediaries
Investor axis£ -> £££
Commercial axisResearch -> £
isis-innovation.com
Isis Impacts
• The impact of Isis activities
is seen through the take-up
of new technologies and
ideas that form the basis
for new products and
services.
isis-innovation.com
Publications
Isis on Twitter
@isisinnovation
Isis E-News & IAN E-News
Chinese Isis E-News
isis-innovation.com
Oxford University Technology Spin-outs (post 2000)
2000 7Third Phase, Mindweavers, Oxford BioSignals, Oxford BioSensors, TolerRx, OXIVA, Pharma DM
2001 7OxLoc, Oxford Bee Co, Oxford Ancestors, Novarc, Oxford ArchDigital, Natural Motion, Inhibox
2002 9Pharminox, Minervation, Oxford Biomaterials(Spinox), Zyentia, Oxitec, Oxford Immunotec, Oxford Risk, GlycoForm, BioAnalab
2003 4 Summit(Vastox)* , ReOx, Riotech, OCSI
2004 4 Avacta(OMD)* , G-Nostics, Surface Therapeutics, EKB Technology
2005 5Oxford Nanopore Technologies, Oxford RF Sensors, Oxbridge Pulsars, Celleron, Oxford Catalysts*
2006 7TDeltaS, Oxford Medistress, Particle Therapeutic, Aurox, Oxford Advanced Surfaces* , Cytox, OxTox
2007 4 Eykona Technologies, Clinox, Oxford Biodynamics, Crysalin
2008 4 Semmle, Oxford-Emergent TB Consortium, Navetas(ISE), Organox
2009 3 Oxford Financial Computing, Zyoxel, Oxford Yasa Motors
2010 4 OxEms, Kepler Energy, IXO, Oxford PhotoVoltaic
2011 5 Oxyntix, Oxtex, Oxford Multi Spectral, Oxford Imaging Detectors, OCB
2012 4 Intelligent Ultrasound, OxEHealth, Oxford Vacmedix, Run3D
2013 [1] Perspectum Diagnostics
Total external investment to date in 68 spin-outs since 2000: £506m £46m 1st round Seed/Business Angels – £460m follow-on Investment Capital
TT
* Stock exchange listing
isis-innovation.com
Spin-outs – The Players
Shareholder, Director, Consultant
Isis - licence, University shareholding, director (OSEM)
Lawyers
Accountants
Shareholder, Director
CEO, Shareholder
Bankers
Ad
vis
ers
Sh
are
hold
ers
I
N
V
E
S
T
M
E
N
T
FounderResearchers
Isis Technology Transfer Manager
Lawyers
Accountants
Manager (1)Manager (2)?
Investor (1)Investor (2) ?
Bankers
Time
TT
isis-innovation.com
Investment Sources
Oxford University Challenge Seed Fund• Launched with £4m in 1999• University provided £1m; HM Treasury, Wellcome, Gatsby £3m• £5.7m invested in 102 projects – development, seed equity• Resulting in Equity stakes in 31 spin-outs, 4 completed licensing
deals & 33 active technology projects. These 31 spin-outs have attracted £80m seed/venture investment
Oxford Invention Fund• Donations to the University of Oxford as part of Oxford Thinking,
the University’s overall fund raising Campaign• Invest in development of new technologies and innovation from
OxfordIsis Angels Network• Business Angels, Seed/Venture Capital• 100 members• Events, No Charges
isis-innovation.com
Isis Software Incubator, established in 2010
• Support for early-stage software ventures from Oxford University
• Assists the creation and development of a software business opportunity, whether or not a company has yet been incorporated
• Isis provides commercial mentoring, negotiation support, services, desk space, access to business networks
• Projects that have a credible business concept and need:
• Substantial work to develop IP and build a realistic commercial prospect
• With entrepreneurial founders
• But do not need patents, investors, full-time management
isis-innovation.com
Vision for Isis
• Technology
• Innovation
• For People
• From Oxford and elsewhere
• Successful exploitation of new ideas
• Health & Wealth of Society
isis-innovation.com
Conclusions – How Isis Works
• Universities• Technology Transfer is a good thing
• Part of University purpose; may make money for University and researchers
• It does not happen on its own• You need to invest resources in People, Patent budget, Proof-of-Concept
• You need a policy framework• Who owns the inventions; who shares the rewards
• It takes a long time … So start and do not stop.
• Business• Access to technologies, resources and expertise• Help understand universities• Help your business innovate
• Investors• Source of investment opportunities• Home for entrepreneurs
• Government• Stimulates innovation and enterprise• Improves society
isis-innovation.com
Elements
Research BaseUniversities
Research InstitutesResearch Hospitals
GovernmentTax
Grants
BusinessIndustryFinance
Commerce
isis-innovation.com
Elements – Research Base
• Supportive Vice-Chancellor, Rector, Provost, Director• & Senior Researchers
• Research Activity• High volume & quality
• Researcher engagement
• University Policies• IP Ownership / Revenue sharing / Spin-outs• Disputes
• Research Services Office• Manage relationship with Research funders
• Access to Proof of Concept / Seed funds• To accelerate technology transfer
• Technology Transfer Office• Adequately resourced
• Policy• Patent Budget• People• Proof of Concept
• Leadership• Stories• Resources
isis-innovation.com
Publications
Isis on Twitter
@isisinnovation
Isis E-News & IAN E-News
Chinese Isis E-News
isis-innovation.com
Elements – Business & Finance
• Business Networks
• Innovative Technology companies• As Licensees
• Business Angels
• Seed & Venture Capital
• Entrepreneurs
• Professional Advisers• Banks / Accountants / Lawyers / Property
isis-innovation.com
Innovation Funnel
Professor Henry Chesbrough
Open Innovation: The New Imperative for Creating and Profiting from Technology (HBS Press, 2003).
isis-innovation.com
Oxford incubators & science parks
Isis Software Incubator
Oxford Centre for Innovation Oxford Magnet
Begbroke Science Park
Oxford Science Park
Oxford Entrepreneurs
Incubator
Oxford Low Carbon Hub
Oxford Hub
Milton Park
Oxford BioEscalator
Harwell - European Space Agency's Business
Incubation Centre
Science Vale Enterprise Zone
Source: Google Maps
isis-innovation.com
Elements - Government
• Tax incentives• SME Benefits• CGT & Income Tax• Tax credits & Tax relief• ‘Patent Box’
• Grant programmes• Technology Transfer capacity, proof-of-concept• Businesses
• Legislative framework• Intellectual Property• Company law
• Public procurement
• Support & Clarity & Consistency
isis-innovation.com
Elements – A fourth area ?
• Non Governmental Organisations
• Charities
• Foundations
• Not-for-Profits
• Social Enterprise
isis-innovation.com
Elements
Research BaseUniversities
Research InstitutesResearch Hospitals
GovernmentTax
Grants
BusinessIndustryFinance
Commerce
isis-innovation.com
The Innovation System
Recruitment, head-hunters
Angel Networks
Students
Angel Investors
Investment Funds
Accountants
Bankers
Lawyers
Technology Transfer
organisations
University Researchers
Commercial property managers
Journalists
Consultants
Public Relations
Local Government
Hospitals
Government Labs
Research Institutes
Members of Parliament
Incubators
Business networks
Science ParksOther
universities
Industry
Technology companies
Business
Start-ups
‘City deal’
Local Enterprise Partnership
isis-innovation.com
[Isis] helps researchers - and students - who wish to commercialise the results of their research
isis-innovation.com
Themes …
• Impact• Change• Benefits• Academic view of relationships with industry• TT is smaller part of a bigger picture
• Specialisation• Vanity subjects … ?
• Convergence• Technology Transfer• Entrepreneurship – Social & Business• Distributed
• Young people
isis-innovation.com
www.isis-innovation.com
Isis Innovation Ltd, Ewert House, Ewert Place, Summertown, Oxford OX2 7SGT 01865 280830 F 01865 280831 E [email protected]
Register to receive Isis E-News at: www.isis-innovation.com/news/enews Follow us @IsisInnovation
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