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Physical growth of Swiss children from birth to 20 years of age. First Zurich longitudinal

study of growth and development.

(PMID:2737921)

Prader A,Largo RH,Molinari L,Issler CDepartment of Pediatrics, University of Zurich, Switzerland.

Helvetica Paediatrica Acta. Supplementum[1989, 52:1-125]

Type: Journal ArticleAbstract Highlight Terms

No biological terms identified

Physical growth from birth to adulthood in healthy Swiss children born 1954-1956 is described. The data are based

on the First Zurich Longitudinal Study in which 137 individuals of each sex have been followed from birth to

adulthood between 1954 and 1976. Distance standards of 20 anthropometric measurements such as weight, height

and head circumference are presented as mean values and standard deviations or as median values (for weight and

skinfold thickness) with smoothed empirical centiles. Velocity standards are provided for seven anthropometric

parameters. The following standard growth charts for clinical use are presented: weight, length/height and headcircumference in the perinatal period, in the age range of 0-48 months and in the age range of 1-18 years (including

some data on puberty), as well as weight for length/height and height velocity (cross-sectional and peak height

centered). Comparison of the growth standards with those of previous Swiss studies and of recent foreign studies

revealed only minor differences. Various aspects relevant for the clinical use of growth standards, such as

measurement error or secular trend, are discussed.

Course and outcome of chronic pancreatitis. Longitudinal study of a mixed medical-surgical series of

245 patients.

Ammann RW,Akovbiantz A,Largiader F,Schueler G

Gastroenterology[1984, 86(5 Pt 1):820-828]Type: Journal ArticleAbstract Highlight Terms

Gene Ontology(1) Diseases(6)

Over the last 20 yr, 245 patients withchronic pancreatitis (163 with alcoholicrelapsing pancreatitis;145 of them

with calcificpancreatitis)were prospectively studied at regular intervals with particular regard to pain, pancreatic

functions, calcifications, pancreatic surgery, and survival. The median period of observation in the group with

alcoholic relapsing calcificpancreatitis was 10.4 yr. In this group of 145 patients, 85% experienced lasting pain

relief within a median time of 4.5 yr from onset. A gradual increase of pancreatic calcifications and pancreatic

dysfunction was observed with increasing duration of the disease. Pain relief was accompanied by a marked increase

in pancreatic dysfunction and calcification. Of 163 patients with alcoholicrelapsing pancreatitis,87 (53%) needed

no pancreatic surgery. Seventy-six patients (47%) with recurrent or persistent severe pain, mainly due to

pseudocysts (n = 56), underwent either a cyst drainage procedure (n = 22), papillotomy (n = 4), distalpancreatectomy (40%-60%, n = 24), or Wirsungo-jejunostomy (n = 26). The proportion of patients experiencing

lasting pain relief was similar in the operated and nonoperated group of patients. In both groups lasting relief from

pain was correlated with the duration of the disease and was associated with marked pancreatic dysfunction. The

50% survival time in alcoholicchronic pancreatitis (with or without pancreatic surgery) was 20-24 yr (after onset),

thus markedly shorter than in nonalcoholicpancreatitis.Of the 245 patients, 86 died. About 20% ofdeaths were

related topancreatitis and its complications. Most extrapancreatic causes ofdeath weremalignancies,cardiovascular

diseases,severeinfections,and nonpancreatic surgery.
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