Stratus OCT Software Version 4.0Real Answers in Real Time.
C a t a r a c t l G l a u c o m a l R e t i n a l R e f r a c t i v e
2Stratus OCT provides a higher level of diagnostic insight - a
significant contribution to therapeutic confidence across a
broad spectrum of ophthalmic diseases. Using near-infrared
frequency light, Stratus OCT reveals an in vivo cross-
sectional view with an axial resolution of 10 m, and
quantitative analysis of the retinal layers.
In the Stratus OCT image display, retinal layers with the
highest reflectivity appear red. In a healthy retina, these
include the nerve fiber layer, retinal pigment epithelium
and choriocapillaris. The layers that exhibit minimal
reflectivity appear blue or black, such as the photoreceptor
layer, choroid, vitreous fluid or blood.
Stratus OCTAdd depth to your diagnosis.
Inner Limiting MembraneNerve Fiber Layer
Ganglion Cell Layer
Inner Plexiform Layer
Outer Plexiform Layer
Junction of Inner and OuterPhotoreceptor Segments
Retinal Pigment Epithelium
Choriocapillaris
Junction of Inner and
Outer Photoreceptor
Segments
Retinal Pigment
Epithelium/
Choriocapillaris
Choroid
Inner Limiting
Membrane
Nerve Fiber
Layer
Ganlion Cell
Layer
Inner Plexiform
Layer
Outer Plexiform
Layer
3Stratus OCT reveals the retinal layers in high-resolution, cross-sectional views, offering insight for diagnosis,
therapy and ongoing management of retinal disorders.
Obtain real-time non-invasivehistology of live tissue.
Cystoid Macular Edema Central Serous Chorioretinopathy
Age-related Macular Degeneration
with Overlying Cystoid Macular Edema
Macular Hole with Operculum
Diabetic Macular Edema Epiretinal Membrane with Lamellar Hole and Cystoid Macular Edema
Branch Retinal Vein Occlusion RNFL Loss
Glaucoma Normal
4Diabetic Retinopathy
Stratus OCT reveals and measures diffuse macular thick-
ening and loss of foveal contour
Intraretinal cysts and fluid accumulation are identifiable
as areas of low reflectivity in the cross-sectional scan
Post-treatment resolution of retinal thickening can be
quantified and monitored
Epiretinal Membrane
Stratus OCT scan shows the epiretinal membrane as a
highly reflective band on the inner retinal surface
Separation of the membrane from the retina is visible in
areas
Underlying retina is thickened, with loss of normal foveal
contour
Age-related
Macular Degeneration
Disruption of RPE, caused by neovascularization and
drusen, can be visualized
Pockets of interretinal fluid are visible as areas of reduced
reflectivity
Structural changes resulting from therapy can be quanti-
fied and monitored
Visualize andanalyze retinal disorders.
5Retinal Nerve Fiber
Layer Analysis
Analysis of RNFL aids in identification of early glaucoma-
tous loss
Circular scans of 3.4 mm diameter around optic nerve
head provide measurement of RNFL in the peripapillary
region
RNFL thickness measurement is graphed in a TSNIT orient-
ation and compared to age-matched normative data
Optic Nerve Head Analysis
Radial line scans through optic disc provide cross-
sectional information on cupping and neuroretinal rim
area
Disc margins are objectively identified using signal from
end of RPE
Key parameters include cup-to-disc ratio and horizontal
integrated rim volume1
Macular Thickness Analysis
Thinning of the macula may reflect glaucomatous loss
Structural analysis of retinal sublayers reveals macular
complications
Cross-sectional view provides visualization and measure-
ment of retinal layers
Detect glaucoma damage at anearly stage.
6Retinal Thickness Report
Scan Protocol: Fast Macular Thickness, Macular Thickness, Line, Cross Hair
Used for: Assessment of overall macular region or specific areas of interest
Patient Information
Scan Image The image with the lowestsignal strength or with a datamessage will be shown tofacilitate operator review.
Signal Strength Numbers range from 0 (weak)to 10 (strong). Analysis algo-rithm may fail on scans withlow signal strength; therefore,images with a signal strengthbelow 5 should not be usedfor analysis.
Data Message Scan Too High, Scan TooLow or Missing Data mes-sage will be shown, if appli-cable, regarding placementand completeness of scan.
Retinal Thickness Displayed for A scan indicated. This corresponds to A scan (shown here) selected on thickness chart.
Caliper Length Measurement indicatesdistance between calipers if they are placed on scanimage during analysis.
Scan Information
Fundus ImageScan should be centered on fovea.
LegendArrow indicates direction and angle of individual scandisplayed in scan image.
Normative DataDistribution is indicated by a stoplight color code, described in detail inside back cover.
Thickness ChartGraphic display of retinalthickness. Colored bandsdemonstrate range of normative data.
Stratus OCT Printout Software Version 4.0
7Retinal Thickness Tabular Output
Scan Protocol: Radial Lines, Fast Macular Thickness, Macular Thickness
Used for: Imaging and measurement of macular pathology
Patient Information
Scan Image The image with the lowestsignal strength or with a datamessage will be shown tofacilitate operator review.Fundus ImageScan should be centered on the fovea.
Signal Strength Numbers range from 0 (weak)to 10 (strong). Analysis algo-rithm may fail for scans withlow signal strength; therefore,images with a signal strengthbelow 5 should not be usedfor analysis.Data Message Scan Too High, Scan TooLow or Missing Data mes-sage will be shown, if appli-cable, regarding placementand completeness of scan.Map Thickness is displayed using acolor scale. A normal eye willbe displayed as blue centrally.Orange and red indicate greater thickness. Legend for color scale appears near bottom right of page.Sector AveragesNumerical values indicateaverage thickness of eachsector. Colors within each sector indicate comparison to normative data.Scans Used If any of the 6 radial linescans has been deselected,analysis might be incomplete.
Scan Information
Map DiametersDiameters at which sector averages are calculated. Can be 1.0, 2.22 and 3.45 mm diameters or 1.0, 3.0 and 6.0 mm diameters as shown here.
Legend Normative data is displayed in stoplight color code, described in detail inside back page.
Color Scale For thickness maps.
Normal distribution,macula thickness normative data,Carl Zeiss Meditec.
Parameter Normal RangeFovea Minimum: 135 215 mMeasurement at center of fovea where radial scan lines intersect
Average ThicknessFovea 168 239 mTemporal Inner Macula 240 294 mSuperior Inner Macula 243 296 mNasal Inner Macula 240 297 mInferior Inner Macula 246 297 mTemporal Outer Macula 199 276 mSuperior Outer Macula 207 256 mNasal Outer Macula 198 274 mInferior Outer Macula 207 256 m
RatiosSuperior/Inferior Outer 0.832 1.222Temporal/Nasal Inner 0.800 1.227Temporal/Nasal Outer 0.557 1.845
VolumeFovea 0.13 0.19 cubic mmTemporal Inner Macula 0.38 0.46 cubic mmSuperior Inner Macula 0.38 0.46 cubic mmNasal Inner Macula 0.38 0.47 cubic mmInferior Inner Macula 0.39 0.46 cubic mmTemporal Outer Macula 1.06 1.46 cubic mmSuperior Outer Macula 1.10 1.36 cubic mmNasal Outer Macula 1.05 1.45 cubic mmInferior Outer Macula 1.10 1.35 cubic mmTotal Macula Volume 6.18 7.42 cubic mm
8CompositeDiagramYellow line indicatesindividual scan selectedand displayed above.
Fundus ImageCan be used to verify scan placement.
Scan List For each of the 6 radial line scans,this indicates thedate when the scanwas last adjustedand saved.
Cup Area The area within the green outlineon the composite diagram.
Cup Volume Volume of cup areaon the topographicdisplay.
Cup Offsetfor TopoDefault is 150 manterior to disc.Represents edge of blue shading ontopographic display -the surface of the cup as if it were filled with water.
Optic Nerve Head Analysis Report
Scan Protocol: Optic Disc, Fast Optic Disc
Used for: Evaluation of the optic disc
Patient Information
Cup MarkersThe edge of the cup is indicatedwith a green dot on the scanimage and a green x on thecomposite diagram.RPE MarkersThe end of the RPE is indicated.Shown blue on the scan image,red on the composite diagram.Signal Strength Numbers range from 0 (weak)to 10 (strong). Analysis algo-rithm may fail on scans withlow signal strength; therefore,images with a signal strengthbelow 5 should not be used foranalysis.Optic Nerve HeadResultsData are derived from the 6 radial line scans.Vertical Integrated Rim AreaTotal volume of RNFL tissue inthe rim is obtained by multiply-ing the average of the 6 indivi-dual rim areas by the circumfe-rence of the disc. Normal valuesare 0.36 0.08 cubic mm.2Horizontal Integrated Rim Width Total rim area is obtained bymultiplying the average of the 6 individual nerve widths by thecircumference of the disc.Disc Area The area within the red outlineon the composite diagram.Cup Area The area within the green outli-ne on the composite diagram.Rim AreaDisc area minus cup area.Cup/Disc Area Ratio Ratio of cup area to disc area.Cup/DiscHorizontal RatioRatio of the longest horizontalline across the cup to the longest horizontal line acrossthe disc.Cup/Disc Vertical RatioRatio of the longest vertical line across the cup to the
longest vertical line acrossthe disc.
Scan Information
Individual Radial Scan AnalysisData relates only to the indi-vidual scan image displayed.Rim Area Indicated with red shading onscan image, this area is bound-ed by the cup diameter line anda line from the RPE marker tothe anterior surface of the disc,at a 90-degree angle to the cupdiameter line. Average NerveWidth@Disc The average of the nerve bund-le widths at the disc on eachside. Nerve bundle width indi-cated by yellow line from RPEmarker to anterior surface.Disc Diameter Illustrated and measured on a straight line between the 2 RPE markers. Blue line onscan image.Cup Diameter Illustrated and measured on a straight line parallel to, and150 m anterior to, the discdiameter line. Red on image,green on diagram, this line isadjustable.Legend Arrow indicates direction and angle of individual scandisplayed in scan image.Horizontal Rim Length Disc diameter minus the cupdiameter.Plot BackgroundThere are 3 optional back-grounds; two are similar to atopographic map. Aligned andShaded (default) provides ashaded relief topographic mapand corrects for patient motion.Absolute provides a non-shadedtopographic map with no correction for movement. Noneshows a solid gray backgroundwith no appearance of depth.Cup Offset Point at which cup diameter is measured. Default placementis 150 m anterior to the RPEmarkers; this point is adjustable.
Stratus OCT Printout Software Version 4.0
9Comparison Average RatiosImax/Smax 0.80 1.25Thickest points in inferior and superior quadrantsSmax/Imax 0.77 1.25Thickest points in superior and inferior quadrantsSmax/Tavg 1.70 3.06Thickest point in superior quadrant to average in temporalImax/Tavg 1.69 3.12Thickest point in inferior quadrant to average in temporalSmax/Navg 1.37 2.93Thickest point in superior quadrant to average in nasal
Measurement Average Values
Min-Max 96 154 mDifference between minimum and maximum measurementsSmax 124 189 mThickest measurement in superior quadrantImax 125 194 mThickest measurement in inferior quadrantSavg 97 152 mAverage measurement in superior quadrantIavg 98 156 mAverage thickness in inferior quadrant
Average Thickness 82 118 m
RNFL Thickness Average Analysis
Scan Protocol: RNFL 3.4 mm, Fast RNFL 3.4 mm
Used for: Retinal nerve fiber layer thickness assessment and comparison to normative database
Patient Information
RNFL Thickness ChartPeripapillary RNFL thickness is displayed in TSNIT format.Colored bands demonstraterange of normative data.
Sector AveragesComparison to normative datain each sector is indicated with stoplight colorscheme. Values are displayednumerically.
Quadrant Averages Comparison to normative datain each quadrant is indicated with stoplight colorscheme. Values are displayednumerically.
OD/OS GraphTSNIT line graph displays RNFLthickness in both eyes.Asymmetry may be indicative ofglaucomatous loss.
Scans Used If any of the 3 circular scanshas been deselected, analysismight be incomplete and forthe fast RNFL scan, normativedata will not be displayed.
Legend Normative data is displayed in stoplight color code, described in detail on insideback cover.
Scan Information
Fundus Image To verify scan placement.
Scan Image The image with the lowest sig-nal strength or with a data message will be shown tofacilitate operator review.
Signal Strength Numbers range from 0 (weak)to 10 (strong). Analysis algo-rithm may fail on scans withlow signal strength; therefore,images with a signal strengthbelow 5 should not be used foranalysis.
Data MessageScan Too High, Scan Too Low or Missing Data message will beshown, if applicable, regardingplacement and completeness ofscan.
Tabular Data For each eye, values are compared to normative data and displayed instoplight color code, described in detailon inside back cover.
Normal distribution, RNFL normative data, Carl Zeiss Meditec.
10
Color Legend and Exam Dates
OD
OS
Scan Type:
Scan Date:
Scan Length:
STRATUS OCTRNFL Thickness Serial Analysis Report - 4.0.1 (0056)
DOB: 7/12/1968, ID: NA, Male
Fast RNFL Thickness (3.4)Multiple, See Table
10.87 mm
Signature:
Physician:
RNFL Thickness Serial Analysis
Scan Protocol: Fast RNFL Thickness (3.4), RNFL Thickness (2.27 x disc)
Used for: Comparative analysis of RNFL thickness over time. Can be applied to up to 4 OD and/or 4 OS scan groups
Patient Information
TSNIT Graph Peripapillary RNFL thickness is displayed in TSNIT format.Colors distinguish lines byscan date.
Color Legend and Exam Dates Shows dates of selected scansand corresponding line colors.
Scan Information
Fundus ImageShows most recent scan. Can be used to verify scanplacement.
Scan Image For most recent scan data, the image with the lowestsignal strength or with a datamessage will be shown tofacilitate operator review.
Signal Strength Numbers range from 0 (weak)to 10 (strong). Analysis algorithm may fail on scanswith low signal strength; therefore, images with a signal strength below 5 should not be used for analysis.
Data MessageScan Too High, Scan Too Low or Missing Data message will be shown, if applicable,regarding placement andcompleteness of scan.
Stratus OCT Printout Software Version 4.0
11
Stratus OCT Normative Data.
Stoplight Color Scheme
RNFL Normative Data Display RNFL Normative Distribution
Macula Normative Display Macula Normative Distribution
Of the normal population:
5%
90%
4%
1%
5% fall within the white band
95% fall within or below the green band90% fall within the green band
5% fall within or below the yellow band
1% fall within the red band; considered outside the normal limit
100%
95%
5%
1%
0%
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