Sepsis Awareness Study

Summary Report

Final Report | September 2018 | Prepared for:

Introduction

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Background on Sepsis

Sepsis is a killer. Every year, it kills 270,000 people in the United States – 1 every 2 minutes, more than prostate cancer, breast cancer, and AIDS combined. It is the 3rd leading cause of death overall and the leading cause of death in U.S. hospitals.

Some Facts:

As many as 92% of all sepsis cases originate in the community.

Mortality rates are high. Mortality from sepsis increases by as much as 8% for every hour that treatment is delayed. As many as 80% of sepsis deaths could be prevented with rapid diagnosis and treatment.

Sepsis affects over 30 million people worldwide each year and is the largest killer of children – more than 3 million each year.

More than 1.7 million people in the U.S. are diagnosed with sepsis each year – 1 every 20 seconds and the incidence is rising 8% every year.

Every day, there is an average of 38 amputations in the U.S. as the result of sepsis.

Sepsis is the #1 cause of death in hospitals.

Sepsis is the #1 cost of hospitalization in the U.S. consuming more than $27 billion each year.

Sepsis is the #1 cause for readmissions to the hospital costing more than $2 billion each year.

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Methodology

MethodologyThe survey was conducted online within the United States by Radius Global Market Research on behalf of Sepsis Alliance between May 5 –May 8, 2018 among more than 2,000 adults living in the U.S. The results were weighted to the U.S. census for age, gender, region and income. Surveys were conducted in English.

About Radius Global Market ResearchRadius Global Market Research (www.radius-global.com) is one of the largest independent market-research companies. For more than 50 years, the business has partnered with global marketers to develop insight-based strategies that drive brand performance. A superior level of senior team involvement is the hallmark of Radius GMR’s approach. Radius GMR is based in New York. Global operations include London-based Radius Europe, Radius MEA in Dubai, and Radius Asia in Beijing.

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65% in 2018

58% in 2017

55% in 2016

44% in 2015

65% of U.S. adults have heard the term sepsis, when just 4 years ago it was at 44%.

Executive Summary

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Executive Summary

! Sepsis awareness has significantly increased to 65% over 58% in 2017. This means more than 16 million more adults are aware of sepsis in 2018 compared to 2017.

! Females are more likely to have heard the term than males (68% vs. 63%).

! Fewer than half (48%) of adults say that an infection is a symptom of sepsis.

!More than a third (36%) say they do not know the symptoms of sepsis, while a majority of adults (94%) say they can identify the symptoms of stroke, even though sepsis is twice as common and twice as deadly as stroke.

! Only 33% are at least very aware of sepsis, while 72% are at least very aware of stroke.

! Only 12% correctly identify all four sepsis symptoms, while 25% correctly identify all four stroke symptoms.

! Nearly three quarters (73%) of adults strongly agree that you need to seek urgent medical attention if you see signs of stroke, yet only half (50%) strongly agree that you need to if you see signs of sepsis.

Details

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Annual Awareness LevelMore than 150 million Americans are now aware of sepsis, an increase of

more than 16 million from 2017

10%

32%

58%

8%

26%

65%

0 10 20 30 40 50 60 70

Not sure

No

Yes

20182017

N = 2105Have you ever heard the term sepsis?

10

Sepsis awareness levels have grown dramatically with advocacy over the yearsThere are now more than 60 million Americans who are aware of the term sepsis compared to 2012.

0%

81%

19%

14%

46%

40%

10%

32%

58%

8%

26%

65%

0% 50% 100%

Not Sure

No

Yes

Sepsis Awareness

2018 Online2017 Online2012 Online2003 Telephone

*"CANNOT"TREND"THE"DATA"FROM"ONE"METHODOLOGY"TO"ANOTHER."MAY"NOT BE"EQUAL"TO"100%"DUE"TO"ROUNDING.

11

Awareness Levels Among Age GroupsThere is no significant difference in awareness levels across age groups.

0

10

20

30

40

50

60

70

80

18-34 35-44 45-54 55-64 65+

No Not sure Yes

N=2,105Have you ever heard the term sepsis?

12

Many conditions, including Ebola and malaria, have higher awareness levelsthan sepsis

Condition At least somewhat aware

Never heard of Never heard of/Just heard the name

Cancer 95% 2% 7%

Diabetes 94% 2% 5%

Stroke 92% 3% 8%

AIDS 91% 2% 9%

Alzheimer’s 91% 6% 9%

Ebola 77% 5% 23%

Malaria 77% 5% 23%

COPD 73% 10% 27%

ALS 69% 11% 32%

Sepsis 57% 25% 42%

MRSA 47% 39% 53%

C-diff 32% 56% 68%

Dengue Fever 33% 44% 67%

N=2,105How aware are you of each of the following conditions?

13

While more than 1.7 million adults are diagnosed with sepsis each year, more than 1/3 do not know the symptoms.

45%48%

27%

37%

8%12%

8%5%

0%

20%

40%

60%

80%

Symptoms

Mentaldecline

Extremely ill

Pain in left shoulder/

arm

Dry mouth Heartburn Other

N=2,105Which of the following, if any, are the symptoms of sepsis?

! 36% say they do not know the symptoms of sepsis

! Yellow highlights sepsis symptoms

Temperature(higher or

lowerthan normal)

Infection

14

The majority of adults can identify the top symptoms of stroke.

76%

69%

79%

54%

22%19%

6%11%

0%

20%

40%

60%

80%

Symptoms

Speechdifficulty

Blurredvision

Stabbingpain with

deep breath

Nausea/vomiting

Frequent urination

Excessive thirst

N=2,105Which of the following, if any, are the symptoms of stroke?

! 6% say they do not know the symptoms of stroke

! Yellow highlights stroke symptoms

Facedrooping

Armweakness

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Sepsis is twice as common and twice as deadly as stroke, yet nearly 70% believe that there are

more deaths from stroke than sepsis in a year in the U.S.

92%

90%

69%

60%

29%

84%

8%

10%

31%

40%

71%

16%

You need to seek urgent medical attention if you see signs of a STROKE

You need to seek urgent medical attention if you see signs of SEPSIS

There are more deaths from stroke than sepsis in a year in the US

Sepsis is not as common as a stroke

Sepsis does not start with an infection

I have heard more about stroke than sepsis

Agree Disagree

N = 2,105How much do you agree or disagree with the following statements?

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While awareness of sepsis continues to rise, it is still not well understood. Sepsis kills more than

270,000 people each year in the U.S., yet only half strongly agree that you need to

seek urgent medical attention if you see signs of sepsis.

N = 2,105How much do you agree or disagree with the following statements?

73%

50%

18%

12%

8%

44%

27%

50%

82%

88%

92%

56%

You need to seek urgent medical attention if you see signs of a STROKE

You need to seek urgent medical attention if you see signs of SEPSIS

There are more deaths from stroke than sepsis in a year in the US

Sepsis is not as common as a stroke

Sepsis does not start with an infection

I have heard more about stroke than sepsis

Strongly Agree

For more information, contact:

radius-global.com

Radius U.S. Radius Europe Radius MEA Radius Asia

Clear thinking for a complex world.

Jill L. GressVice President

585.734.2699jgress@radius-global.com