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ALEXANDER DAVID
21030111130142
ASIH MUSTIKASARI
21030112130064
VIRANTIKA WIJI PANGESTU21030114120058
ANANDA FITRIANA
21030114120088
STEPHANUS STEVEN HALIMKESUMA
21030114140182
Bioceramics
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Defnisi Bioceramics
Bio disini berarti Biomaterialadalah materialpasi yang digunakan dalam dunia kesehatan,yang akan diinteraksikan dengan sel-sel hidup.
Ceramics berarti benda yang memiliki long-range order crystal arrangement.
Bioceramicskeramik yang digunakan untuk
mengganti atau memperbaiki bagian tubuhdari sistem muskoloskeletal (ref Dr. N. H.Aloorkar
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Sejarah Bioceramics
!
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"
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Biocompatibility:Biocompatibility was defined as, the ability of a material
to perform with an appropriate host response in a specific
application.
Components of biocompatibility:
Cytotoxicity (systemic and local)
enotoxicity
!"ta#enicity
Carcino#enicity
$mm"no#enicity #
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%enis & %enis Bioceramics
$
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'. Bioinert:
!aintain their physical and mechanical properties while
in host.
esist corrosion and wear.
a*e a reasonable fract"re to"#hness.
+ypically "sed as str"ct"rals"pport implant s"ch as bone
plates, bone screw and femoral
heads.
%
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'. -/!$0- (-l123):
+he main so"rce of al"mina or al"mini"m oxide is ba"xite
and nati*e cor"nd"m. i#hly stable oxide & *ery chemically inert.
ow fract"re to"#hness and tensile stren#th & hi#h
compression stren#th.
4ery low wear resistance.
5"ite hard material,
Contin"ed7.
&
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-/!$0-
i#h hardness 8 low friction 8 low wear 8 inert to in *i*oen*ironment.
$deal material for "se in:
9rthopaedic joint replacement component, e.#. femoral
head of hip implant.
9rthopaedic loadbearin# implant.
$mplant coatin#.
ental implants.
Contin"ed7.
'
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1. Bioacti*e:
irect and stron# chemical bond with tiss"e. ;ixation of implants in the s
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lassceramics are crystalline materials obtained by the
controlled crystalli>ation of an amorpho"s parent #lass.
Controlled crystallisation re?"ires:
Specific compositions.
/s"ally a twosta#e heattreatment.
Controlled n"cleation
Controlled crystalli>ation will
initiate #rowth of crystal of
small "niform si>e.
lass ceramics:
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3. Bioesorbable:
Chemically bro
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=xamples of esorbable Bioceramics:
'. Calci"m phosphate
1. Calci"m s"lfate, incl"din# plaster of 6aris
3. ydroxyapatite
@. +ricalci"m phosphate
A. ;erriccalci"mphosphoro"s oxides
. Corals
Contin"ed7
!
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Synthetic ceramic:
Calci"m phosphate and ydroxyapatite:
Can be crystalli>ed into salts s"ch as ydroxyapatite.
ydroxyapatite (-6) has a similar properties with
mineral phase of bone and teeth.
$mportant properties of -6:
=xcellent biocompatibility.
;orm a direct chemical bond with
hard tiss"e.
Contin"ed7
"
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Natural ceramic:
Biocoral:
Corals transformed into -6.
Biocompatible.
;acilitate bone #rowth.
/sed to repair tra"mati>ed bone, replaced disease bone and
correct *ario"s bone defect.
Bone scaffold.
Contin"ed7
#
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-pli
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Bioceramics as a root repair material:
e.#. =ndose?"ence
%
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Bioceramics as dr"# deli*ery system:
&
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Bioceramics in optholmolo#y:
e.#. Bioacti*e lass Ceramic, -l"mini"m 9xide
'
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Bioceramics in 9rthopaedics:
*)
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6"lp Cappin# ith Bioceramics:
e.#. Calci"m ydroxide, Dinc 9xide ="#enol (D9=)
*
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Bioceramics ith Sa"na:
+hermal properties help to red"ce fl"id (water) and
acc"m"lated toxins.
**
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Hydro+iapatite (HA
HA adalah salah satu yang paling banyak digunakan
biomaterial untuk rekonstruksi kerangka dan aringan gigi
karena siatnya yang tidak beracun dan biokompatibel
bahan yang dapat digunakan dengan aringan tulang(Nemirkol et al., *)*
emilihan biomaterial yang tepat sangat diperlukan dalam
proses pengganti tulang, antara lain mudah diperoleh,
biokompatibel, eekti, dan tidak toksik (iyani, *))#.
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Hydro+iapatite (HA
roses pembuatan hidroksiapatit dari limbah tulang sapi dia/ali
dengan dikumpulkannya limbah tulang sapi, kemudian direndam
dalam air yang telah ditambahkan cairan antiseptik. 0etelah itu,
tulang sapi direndam kembali dengan Na1H, lalu dicuci
menggunakan air mengalir. 0elanutnya, tulang dikeringkan
secara alami. 0etelah itu, tulang dipanaskan pada temperatur '))
. 0etelah proses pemanasan, material hidroksiapatit dihaluskan
menggunakan stemper dan mortir hingga berbentuk serbuk.
0erbuk itulah yang disebut dengan serbuk hidroksiapatit yang
dapat digunakan sebagai bahan tambal gigi (2usuma/ardani,
*)*.
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eferences:
'. r. ie#er ., eyen S., r. Eobel S., r. eber ., +he "se of bioceramics in dental
and medical applications, i#ital ental 0ews., 122F, '3.1. eness . and Ben0issan B., $nno*ati*e Bioceramics, !aterials ;or"m 4ol. 1G
(122@) '2@ & ''@.
3. %ayaswal . 6., an#e S. 6., Ehali
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H. obert B. eimann, !aterials Science of Crystalline Bioceramics:- e*iew of
Basic 6roperties and -pplications, C!/. %o"rnal, 4ol. '('), 1221, 13@G.
F. Ear
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