PORTAL VEIN EMBOLIZATIONTOP 5 TIPS
William S Rilling MD, FSIR Professor of Radiology and Surgery
Vice Chair, Clinical OperationsDepartment of Radiology
Medical College of Wisconsin
CIO 2019
DISCLOSURES
• Research support : BTG, Siemens Healthcare, Sirtex
• Consultant : B Braun, BTG, BD/Bard, Terumo, Boston Scientific
PVE : TOP TIPS
• Patient selection• Imaging, volumes, timing, ? Y90
• Discuss segment 4• Embolization agents• Embolization technique
• Adjunctive methods
PATIENT SELECTION
• Test of time : trying to avoid PVE without resection
• Imaging : PET, MRI• Consider radiation lobectomy
PVE PATIENT SELECTION• 358 patients PVE
• Extrahepatic disease progression • Intrahepatic disease progression • Medical issues • Insufficient hypertrophy
• 282 patient to OR• 76 aborted resection in OR
• 118/358 ( 33%) do not go on to resection, outcomes not reported
Adapted from R Salem Shindoh et al. J Gastrointest Surgery 2014
RADIATION LOBECTOMY VS PVE
PVE : SEGMENT 4 ?
• More hypertrophy of FLR if segment 4 embolized
• Defining anatomy sometimes challenging
• Risk to FLR• Discuss with surgeon PRIOR to PVE
PVE EMBOLIZATION AGENTS
• Particles : PVA, spheres• Coils• Liquid agents : glue, onyx• combinations
PVE TECHNIQUE
• Ipsilateral portal v access• Neff set
• 5- 6 fr 25 cm sheath into RPV• Reverse curve catheter +/-
microcatheter• Segmental embolization
62 y.o. with ICC, ECOG 0
3:1 or 4:1 lipiodol: glue
baseline 6 weeks post PVE
ADJUNCTIVE TECHNIQUES
• Total venous deprivation• Right hepatic v embolized concurrently• Increases hypertrophy rate and FLR
volume
• Can also be used to salvage inadequate FLR hypertrophy
PVE SUMMARY
• Patient selection is key• Consider radiation lobectomy approach in
some patients
• Choose a consistent embolization agent• Discuss segment 4 on case by case
basis• Segmental approach
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