MURLI KRISHNA PHARMA
OLISTAT PELLETS 50%
COMPANY PROFILE Murli Krishna Pharma is an EU-GMP/ WHO-GMP and PIC/S
approved plant. We manufacture pre finished formulation intermediates that can
be directly employed into formulating solid dosage forms, can be blended with suspension base for use in suspensions. We also have developed nano particles for direct use in ophthalmic solutions and injectables
We are one among the global top 10 NDDS manufacturers and one of the five regulatory compliant and regulatory approved manufacturers of pre finished formulation intermediates.
We provide a complete patient friendly solution to the generic manufacturers of the World.
MURLI KRISHNA PHARMA
Factory-MKPPLThe facility of Murli Krishna Pharma Pvt. Ltd. for manufacturing of coated pellets, is situated at Plot. No. D-98 MIDC, Ranjangaon. The facility is certified by Food and Drug administration Maharashtra State.
Factory Registration and License No.: PD - 162 and PD - 115
Images of Extruders & Spheronizers in our R &D
Orlistat 50.0% Pellets -Fill Weight
Mesh Size Dose Fill Wt. Capsule Size Capsules per kg of pellets
14 # 20 / 18 # 30 120 mg 240 mg 1 4166
14 # 20 / 18 # 30 60 mg 120 mg 3 8333
18 # 30 120 mg 240 mg 2 4166
18 # 30 60 mg 120 mg 4 8333
Number of Capsules per kg of MKPPL Pellets
Pellets offer a more uniform surface and also have a particle size distribution in a narrow window compared to granules. This ensures a better dose uniformity and also a more uniform transfer of dose.
Description:Anti-Obesity drugReversible inhibitor of lipases. Used for losing weight
Patent HoldersRoche- Switzerland
Our Non-InfringementPatent non-infringing process
Comparative Dissolution Data
Time(Min)
Dissolution (%)Of MKPPL
B.No. PDL/ORE-010609
Dissolution (%) of XENICAL B.No. M1425U
0 0 0
1071.5 76.0
2083.4 88.1
3090.1 93.5
4592.6 96.9
6096.9 99.3
ORLISTAT PELLETS
5. Dissolution Profile:
Differential Factor (F1) was found to be 4.25 (0-15 is acceptable)Similarity Factor (F2) was found to be 69.48 (50-100 is acceptable)
Conclusion: From the above values of F1 and F2, it can be concluded that Orlistat pellets manufactured at Murli Krishna Pharma compare favorably with that of the Innovator product.
Dissolution Profile
SPECIFICATIONS-MKPPL
Variations of the Product:
Percentage: 50%Mesh Size: 14 # 20, 18 # 30
Documentation Availble:DMF in CTD format is availableStability Data- Accelerated and Long term stability is available.
Registrations :Our product was registered in Iran, Mexico, Columbia, Switzerland, Europe, Egypt, Romania
Bangladesh, Pakistan, Turkey, etc…
ORLISTAT PELLETS
Orlistat 50.0% Pellets -Fill Weight
Mesh Size Dose Fill Wt. Capsule Size Capsules per kg of pellets
14 # 20 / 18 # 30 120 mg 240 mg 1 4166
14 # 20 / 18 # 30 60 mg 120 mg 3 8333
18 # 30 120 mg 240 mg 2 4166
18 # 30 60 mg 120 mg 4 8333
Number of Capsules per kg of MKPPL Pellets
Pellets offer a more uniform surface and also have a particle size distribution in a narrow window compared to granules. This ensures a better dose uniformity and also a more uniform transfer of dose.
THE PRODUCT PORTFOLIO
Product -Commercialized
Recently Developed Under-Development
Orlistat Pellets Aprepitant Pellets Mycophenolate Mofetil Pellets
Clarithromycin Pellets/Granules
Azithromycin Taste Masked Granules
Paclitaxel Nano Particles
Itraconazole Pellets Sirolimus Micro Pellets Brinzolamide Micro Pellets
Lansoprazole Pellets/Micro Pellets
Tacrolimus Pellets/Micro pellets
Duloxetine HCL EC Pellets
Esomeprazole Pellets Tamsulosin HCL SR Pellets
Voriconazole Micro Pellets
Pantoprazole Pellets Mesalamine Pellets Venlafaxine SR pellets
Omeprazole Pellets Everolimus Micro Pellets
DOCUMENTS AVAILABLE
DOCUMENTATIONS:
DMF: EDMF in CTD format is available.
STABILITY DATA: Both accelerated & Long Term stability is available.
WORLDWIDE - SUPPLIES
MKPPL product was Exported to: Mexico Columbia Turkey Iran Egypt Cyprus Bangladesh
For further information please feel free to contact our Marketing team.
Kind Attn: Ms. Sudha Murli Krishna Pharma P. Ltd INDIA
D-98, M.I.D.C. Ranjangaon, Tal. ShirurDist. Pune 412209, Maharashtra, INDIATel: +91 2138 675613 Web: www.mkppl.com
E-mail id: [email protected] Mobile: 0091 9225507296
CONTACT US
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