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Page 1: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OPIOID USE DISORDERS IN DENTAL MEDICINE

Kelly S. Barth, DOMedical University of South Carolina

©AMSP 2014

© AMSP 2014 1

Page 2: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

“EPIDEMIC” OF Rx OD DEATHS

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Page 3: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

ACCIDENTAL OD DEATHS

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Page 4: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

WHY Rx OPIOIDS?

• Seen as safer than street drugs

• social stigma

• cost

• Wide availability

• Pain

© AMSP 2014 4

Page 5: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

14% 18%8%

__________________________________________________________________

WHY DENTISTS?

PCPsIMs Dentists 5

TOP OPIOID PRESCRIBERS

Page 6: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

THIS LECTURE WILL REVIEW

• Overview of orofacial pain management

• Recognition of opioid use d/o (OUD)

• Prevention & referral for OUD

© AMSP 2013 6

Page 7: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

© AMSP 2014 7

Joe

25 yo student

Wisdom tooth

FH drugs

Alcohol 3x/week

Joanne

38 yo lawyer

Friday distress

Toothache

“Only oxycodone”

Edna

60 yo teacher

One kidney

Tooth extraction

#30 hydrocodone

Page 8: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OROFACIAL PAIN MANAGEMENT

• Definition & classification

• Diagnosis

• Treatment

© AMSP 2013 8

Page 9: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OROFACIAL PAIN

• Unpleasant sensation face or mouth

• Prevalent - 20% US

• Costly – 32 billion/yr© AMSP 2014 9

Page 10: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

MouthTeeth GumsMucosaFace Joints

Acute

Chronic

CLASSIFICATION

Location Duration

© AMSP 2013 10

Page 11: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

DIAGNOSIS

• Review history

• Exam–Extra/intraoral

–Reproduce pain

• X-rays

© AMSP 2014 11

OnsetLocationDurationCharacterAggravatingRelievingTimingSeverity

Page 12: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

TREATMENT

•Pulpotomy = 80% ↓ in pain

•Pulpectomy (root canal) = 75% ↓ in pain

© AMSP 2014 12

SURGERY IS

EFFECTIVE

Page 13: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

MEDICATIONS

• Non-steroidal anti-inflammatories (NSAIDs)

• Acetaminophen (Tylenol)

• Combination therapy

• Prophylactic steroids

• Mandibular injections

© AMSP 2014 13

1STLINE =NON-

OPIOIDS

1STLINE =NON-

OPIOIDS

Page 14: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

REMEMBER

• Ibuprofen 400mg + acetaminophen 1000mg

• Better pain relief than opioid combo!

• Fewer side effects

• No > 4,000mg acetaminophen/day

© AMSP 2014 14

Page 15: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

SOMETIMES OPIOIDS ARE NEEDED

“Opiophobia” “No pain left behind”

Responsible Opioid Pharmacotherapy15

Page 16: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OPIOIDS

• Proteins

• Morphine-like actions

• Stimulate opioid receptors

• Reduce pain

© AMSP 2014 16

OPIOID

Page 17: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OPIOID RECEPTOR LOCATIONS

BRAIN

SPINALCORD

© AMSP 2014 17

GI TRACT

NERVES

Page 18: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

Endogenous Opioids

OPIOID CLASSIFICATION

© AMSP 2014 18

Page 19: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OPIOID CLASSIFICATION

© AMSP 2014 19

Page 20: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OPIOIDS WORK WELL FOR ACUTE PAIN

BUT HAVE LIMITATIONS© AMSP 2014 20

Page 21: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OPIOID SIDE EFFECTSSedation

Dizziness

Nausea

Memory

RespirationsItching

Constipation

Tolerance

Withdrawal

© AMSP 2014 21

Page 22: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OPIOID SIDE EFFECTS

© AMSP 2013 22

Page 23: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

THIS LECTURE WILL REVIEW

• Overview of orofacial pain management

• Recognition opioid use d/o (OUD)

• Prevention & referral for OUD

© AMSP 2014 23

Page 24: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

RECOGNITION OF OUD

• Non-Medical Use

• Opioid Use Disorder

• Physiologic Dependence

© AMSP 2014 24

Terminology

Page 25: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

NON-MEDICAL USE (NMU)

Use Rx for + feeling/high–2 million new NMUs/year

–2nd only to THC

–risk in adolescents

–Obtain from family/friend

© AMSP 2013 25

Page 26: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

OUD VS. DEPENDENCESymptoms

OUD

Loss of control

in function

Use despite negatives

Compulsive use

Craving

Dependence

Tolerance

Withdrawal

No loss of control

Functioning well

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Page 27: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

Start opioid

Pain

Euphoria

Change source

Tolerance

Doc mg

Tolerance

Pt mg

Use for stress sleep high

Try to

painsleep

w/d

Return to drug

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How does an OUD start?

Run outearly

Page 28: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

RECOGNIZING OUDBehaviors

More clearForging

Steal/borrowing

IV use

Obtained on street

Abuse other drugs

Multiple dose Recurrent Rx loss

Less clearRequest mg

Hoarding

Asking specific Rx

“Doc shopping”

1-2 dose Rx another sx

Psychic effects(Passik & Portenoy 1998)

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Page 29: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

RECOGNIZING OUDSigns

Intoxication Withdrawal

Pain/Distress

Dilated pupils

GI upset/diarrhea

Goosebumps

Euphoria

Constricted pupils

Slurred speech

The “nods”

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Page 30: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

THIS LECTURE WILL REVIEW

• Overview of orofacial pain management

• Recognition opioid use d/o (OUD)

• Prevention & referral for OUD

© AMSP 2014 30

Page 31: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

RESPONSIBLE OPIOID RX

1. “Universal Precautions”

2. Use non pharm, non-opioid 1st

3. Don’t Rx > needed

4. Monitor/balance pain, function, & safety (4 A’s)

5. Educate about safe storage & disposal

6. Recognize and refer OUD treatment

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Page 32: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

“UNIVERSAL PRECAUTIONS”

© AMSP 2013 32

Rx Monitoring ProgramsOpioid Tx Agreements

Page 33: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

NON-PHARM, NON-OPIOID

• Surgery

• NSAIDs/analgesics

• Steroids

• Mandibular injections

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Page 34: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

DON’T RX > THAN NEEDED

Average dental pain = 24 - 48hrs

Left-over meds = major issue

Rx 2-3 days worth, then re-eval© AMSP 2014 34

Page 35: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

PASSIK’S 4A’S PAIN TREATMENT OUTCOMES

• Analgesia (pain relief)

• ADLs (Activities of Daily Living)

• Adverse effects

• Aberrant drug taking behavior

GOAL= Pain Function© AMSP 2014

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Page 36: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

SAFE STORAGE & DISPOSAL

Drug take-back programs The flush list

© AMSP 2014 36

Page 37: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

DIAGNOSE AN OUD?

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THIS DOES NOT WORK… THIS WORKS BETTER . . .

Page 38: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

HAVING THE CONVERSATION

• Empathy (pt is suffering)

• Focus = safety & functioning

• Professionally set boundary

• Lifesaving tx available!© AMSP 2014

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Page 39: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

“LOW” RISK PATIENT

Characterized by

Follows plan/stable

function

Side effect concern

Leftover meds

Management

Universal precautions

Routing monitoring

No extra meds!

Safe storage education

© AMSP 2014 39

Page 40: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

BEWARE THE LOW RISK PT

© AMSP 2013 40

Page 41: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

MODERATE RISK PATIENT

Characterized by Lower risk behaviors

Strong FH

Psych history

Focus on opioids

ManagementUniversal precautions

Non-opioid first!!

Treat psych

Structure/Team© AMSP 2014

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Page 42: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

HIGH RISK PATIENT

Characterized by

In withdrawal

No Rx = urgency

dose > 2x

function

Only opioids

ManagementUniversal precautions

Non-opioid therapy

Max structure

Discuss OUD concern

Refer/Mandate OUD tx!

© AMSP 2014 42

Page 43: OPIOID USE DISORDERS IN DENTAL MEDICINE Kelly S. Barth, DO Medical University of South Carolina ©AMSP 2014 © AMSP 20141.

SUMMARY

• Pain & opioid use are prevalent

• Rx opioid epidemic is ongoing

• Responsible opioid Rx = OUD

• Recognize & refer OUD = death

© AMSP 2014 43