Genuine, inspiring and passionate about omega-3
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About Moller’s Omega-3I. The history of Moller : since 1854- the
longest history.II. About the Quality : the purest & most
natural Omega-3 III. Excellent health care of Omega-3 and
clinical studies
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I. History
• Cod liver oil : over 1000 year ago
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• He introduced “medicine cod liver oil” in 1854 with an impressive quality and taste.
History
Pharmacist Peter Möller (1793 – 1869)
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• Raw material: liver of wild Arctic cod (Skrei) fished off Lofoten and Vesterålen , ones of the clearest waters on the Earth.
• Richness in the most important Omega-3 fatty acids DHA + EPA and vitamins D and A.
Raw material
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Widely international presense
Available in more than 20 countries One of the Best product of Omega-3 in the world
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Möller’s – leading omega-3 brand in many markets
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II. The QualityMöller’s – the purest &most natural omega-3
• Reason to believe Made of wild fish from the world’s purest
seas. Kept in its natural form as oil straight from the
fish. (Triglycerides) Processed gently to preserve all the natural
goodness.
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Highest freshness values
• For all Möller’s products we follow the strict standards and recommendations for oxidation values set by European Pharmacopoeia (Ph.Eur) and GOED (Global Organization for EPA and DHA Omega-3)
• Orkla Health has set internal requirements that are even stricter than the ones put forward by Ph. Eur. and GOED to secure the highest level of freshness.
Möller’s cod liver oil
Möller’s fish oil
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Möller's Oxidation values - Peroxide
Ph.Eur. limit Möller’s limit Möllers average value 2008-2010
Möller’s cod liver oil
Möller’s fish oil
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101520253035
Möller's Oxidation values - Anisidine
Ph.Eur. limit Möller’s limit Möller’s average value 2008-2010
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Securing highest purity• To secure consumption safety of highest degree Moller
employs the art technologies to remove environmental toxins.• We analyse for contaminants regularly and all our results are
below the EU and Möller’s limits with good margin.
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Strict standards for microbiological activity• As of today, there exist no official government requirements
for the maximum allowed levels of microbiological activity in fish oil.
• However, Orkla Health makes sure that the microbiological activity is at a minimum:
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Moller Vietnam
Components 5ml Moller’s Tran Lemon
5ml Moller’s Tutti Fruit
2 capsules Mollers’s Dobbel
Omega 3 1100 mg 1200 mg 700 mg
DHA 600 mg 600 mg 600 mg
EPA 400 mg 400 mg
Other fatty acids 100 mg 200 mg 100 mg
Vitamin D 10 mcg 10 mcg 15 mcg
Vitamin A 250 mcg 250 mcg 250 mcg
Vitamin E 10 mg 10 mg 10 mg
Cod Liver Oil Fish Oil
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III. EXCELLENT HEALTH CARE Omega- 3 fatty acids are a general term for a group
of polyunsaturated fatty acids The longest, most flexible fatty acids among the
marine omega-3 fatty acids are docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA).
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Fatty acid Double bonds Sources
Linoleic acid n-6 Vegetable oils, margarines, grain
α-linolenic acid n-3 Green leaves, linseed, soybean and canola oil
EPA , DHA Marine animals, cod liver oil and fish oil
Food sources of Fatty acids
Source of oil
Saturates Monoenes N-3 N-6
Cod liver 16 51 27 2
Soy 16 23 8 53
Corn 13 27 1.3 58
Rape seed 6 64 9 20
Palm oil 51 39 0.5 10
Coconut 91 7 0 3
Fatty acid composition of vegetable oils, marine oils (% of fatty acids)
United States Department of Agriculture Provisional table on the content of omega-3 fatty acids and other fat components in selected foods.
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Every cell wall in our body has a double layer of phospholipids built from fatty acids.
All cells are constantly rebuilt and changing, and new building blocks are therefore required!
Need to supplement through dietary !
IMPORTANCE OF DIETARY INTAKE
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COD LIVER OIL ALSO CONTAINSVITAMIN D, A and E
• It is not cod liver oil if there is not vitamin (Norwegian pharmacopea).
• The combination is perfect and natural• Bring more benefits to our consumers
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- Reducing risk of atherosclerosis- Inhibition of thrombosis- Anti-arrhythmic effects- Arterial compliance
EPA + DHA AND HEART
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DHA AND VISION
• Supplementation with DHA enhance maturation of infant retina function and visional acuity.
• It is hypothesized that if dietary intake of DHA is increased among elderly, concentration of DHA will increase in retina and increase light sensitivity
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DHA AND BRAIN• Docosahexaenoic acid (DHA) is
the most abundant omega-3 fatty acid in the human brain, increasing in amount when the brain develops and grows, and decrease in amount as we age.
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Research on Möller’s cod liver oil
• During pregancy and lactation To enrich breastmilk with VLC n-3 Effects on brain development – IQ• Effects on risk factors for
Cardiovascular disease Incorporation of marine fatty acids
into blood cells Modulation of inflammtion Lowering of triglyceride levels Modulation of cholesterol levels Reduced platelet aggregation• Correlation studies :CLO intake and
depression
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Pregnancy and lactation• 4 published studies from the Institute for Nutrition research, University of Oslo,
Norway• 10ml Möller’s CLO throughout pregnancy and lactationResults: Supplementation with Möller’s CLO raises omega-3 content of breast-milk, thereby
increasing the supply of these fatty acids to the infant Supplementation with Möller’s CLO reduces maternal plasma lipids such as
triglycerides Supplementation with Möller’s CLO is associated with higher IQ at 4 years of age
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Studies from the Institute for Nutrition research University of Oslo, Norway
Pregnancy and lactation
HELLAND et al, 2008 HELLAND et al ,2003
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Intelligence• Mothers were supplemented with cod liver oil (or a control) during
pregnancy and lactation• Children of supplemented mothers had a higher IQ at 4 years of age
(average = 4.1 points higher)• DHA intake had the strongest correlation with intelligence
Maternal Supplementation with Very-Long-Chain n-3 FattyAcids during Pregnancy and Lactation AugmentsChildren’s IQ at 4 years of age, Pediatrics: 2003
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Research on Möller’s cod liver oilDuring
• During pregancy and lactation To enrich breastmilk with VLC n-3 Effects on brain development – IQ• Effects on risk factors for Cardiova
scular disease Incorporation of marine fatty acids
into blood cells Modulation of inflammation Lowering of triglyceride levels Modulation of cholesterol levels Reduced platelet aggregation• Correlation studies :CLO intake
and depression
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• GISSI study from 1999
Cardiovascular risk factors
From October, 1993, to September, 1995, 11 324 patients surviving recent (3 months) myocardial infarction Randomly assigned supplements of n-3 PUFA (1 g daily, n=2836), vitamin E (300 mg daily, n=2830), both (n=2830), or none (control, n=2828) for 3·5 years. Treatment with n-3 PUFA: significantly lowered the risk of the primary endpoint (death, non-fatal myocardial infarction, and stroke)
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Research on Möller’s cod liver oilDuring
• During pregancy and lactation To enrich breastmilk with VLC n-3 Effects on brain development – IQ• Effects on risk factors for Cardiova
scular disease Incorporation of marine fatty acids
into blood cells Modulation of inflammtion Lowering of triglyceride levels Modulation of cholesterol levels Reduced platelet aggregation• Correlation studies :
CLO intake and cognitive function, diabete and Metabolic syndrom.
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The Lund Cognitive Study• Aim: to test the effect of 5 weeks supplementation with omega-3 fatty
acids on cognition–Used Orkla Health’ PMET oil (Möller’s High Concentrate): 3g omega-3 FA per day–38 subjects, 50-70 years–Placebo-controlled, crossover design–Used cognitive tests to evaluate:• Working memory(WM)• Selective attention
Nilsson et al. Nutrition Journal 2012
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• Results:- Better performance in the
WM-test compared with placebo
- n-3 PUFA lowered plasma triacylglycerides and systolic blood pressure
The Lund Cognitive Study
30 60 90 120
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180
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omega-3kontroll
*
P<0,05
ord ord
siffror
Tid (min)
anta
l rät
t ord
/siff
ror
(max
48p
)
60 1607
8
9
10
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12
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15
omega-3kontroll
P=0,013
resultat på den svåraste delen av testet(max 24p)
ab
Totalt (60 +160min): P=0,015
~8%skillnad
Tid (min)
anta
l rät
t ord
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Type 1 diabetes• 545 cases of
childhood- type 1 diabetes
• A significantly lower risk of type 1 diabetes (adjusted odds ratio: 0.74; 95% CI: 0.56, 0.99).
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Metabolic syndrom• Intervention with diet plus
omega-3 was associated with significant reduction in systolic (−12.2%) and diastolic (−8.2%) blood pressure, serum triglycerides concentration (−21.4%), and insulin resistance (−13.1%) (P<0.05), as well as a reduction in serum IL-6 concentration (−28.5%) (P=0.034).
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HOW MUCH OMEGA-3DO WE NEED?
• Nordic Nutrition Recommendations: 1 gram omega-3 every day.• Norwegian Health authorities recommend vitamin D to infants from 4 weeks
of age. Vitamin D supplement is preferably from cod liver oil.• Subjects with special needs can benefit from larger doses of omega-3.• Joint or heart problems: 2-3 grams of omega-3 daily (American Heart
Association).
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Global recommendations Organization Target Population Recommendation World Health Organization (WHO) General adult population n-3 PUFAs: 1-2% of energy/day
Food and Agriculture Organization of the United Nations (FAO)2
0-6 months DHA: 0.1-.018%E
6-24 months DHA: 10-12 mg/kg bw
2-4 years EPA + DHA: 100-150 mg
4-6 years EPA + DHA: 150-200 mg
6-10 years EPA + DHA: 200-250 mg
Pregnant/Lactating Women EPA + DHA: 0.3 g/d of which at least should be 0.2 g/d
European Food Safety Authority General Adult Population 250mg EPA+DHA /day
Pregnant & Lactating Women 100-200 mg DHA / day in addition to general adult requirements
Children 7-24 months 100 mg DHA / day
Children 2-18 years 250mg EPA+DHA /day
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Moller’s Values Since 1854 – The longest history. Leading omega-3 brand in
Denmark, Norway, Sweden, Finland and many other countries. The purest &most natural omega-3. The best Quality : exceed the European Pharmacopeia. Excellent health care.
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Thanks For Your Attention
Genuine, inspiring and passionate about omega-3
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