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Metabolisme
neurotransmitter
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Problem anda pada blok ini
Pengaruh neurotransmitter pada jiwa
Obat yang dapat untuk therapi
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Jiwa
Apa yang membentuknya
Pikiran
Tingkah laku Kepribadian
dll
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Sel
Jumlah sel dalam tubuh 500maam !ungsinya berbeda"beda
#im$ositimmunitas tubuh
%ritrosit &b mengikat O' Sel Jiwa atau sub organ
Semua sel energi ( )O'(&'O
%n*im dibuat oleh masing"masing sel
Produk masing"masing
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Membrane
+on,a
+on K
,a" K"ATPase
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,eurotransmitter
-00 maam neurotrans mitter
.ntuk psyhiatri / dopamin danserotonin
Therapi / berhubungan denganneurotransmitter ini
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e1nisi neurotransmitter
Defnition: A neurotransmitter is a hemialmessenger that arries2 boosts and modulatessignals between neuronsand other ells in thebody3
+n most ases2 a neurotransmitter is released $romthe a4on terminal a$ter an ation potentialhasreahed the synapse3
The neurotransmitter then rosses the synapti gap
to reah the reeptor site o$ the other ell orneuron3 Then2 in a proess known as reuptake2 theneurotransmitter attahes to the reeptor site andis reabsorbed by the neuron3
http://psychology.about.com/od/biopsychology/f/neuron01.htmhttp://psychology.about.com/od/aindex/g/actionpot.htmhttp://psychology.about.com/od/aindex/g/actionpot.htmhttp://psychology.about.com/od/biopsychology/f/neuron01.htm7/26/2019 Metabolisme Neurotransmittfer
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Sintesis neurotransmitter
eberapa dibentuk dari asam amino
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opamin produksi dansekresi
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,eurotransmitter di selTarget
i$asilitasi 6 protein
Serotonin atau dopamin dikatabolisme
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Sekresi
Serotonin transporter 7pengangkutserotonin8 berikatan dengan ,a( $ollowed by serotonin2 dan )l"3
Sekresi 7releasing8 serotonin3
K( 2 and the transporter 9ips bakout2 ready to reei:e anotherserotonin moleule
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Serotonin is synthesi*ed
amino aid #"tryptophan /Tryptophan hydro4ylase 7TP&8
Amino aid dearbo4ylase
The reation in this pathway that is mediatedby tryptophan hydro4ylase is the rate limitingstep2 meaning that i$ this en*yme is bloked2the synthesis o$ serotonin would be stopped3
Tryptophan hydro4ylase e4ists in two $orms "TP&- and TP&'3 ;hile TP&- is $ound in se:eraltissues2TP&'is spei1ally $ound in ner:es o$the brain3
http://www.news-medical.net/health/The-Human-Brain.aspxhttp://www.news-medical.net/health/The-Human-Brain.aspx7/26/2019 Metabolisme Neurotransmittfer
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serotonin transporter
The reyling o$ serotoninisontrolled by the serotonintransporter3
serotonin pathway dari midbrain keorte4 omponen penting mengatur
a
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Penyebab epressi
Penelitian = multiple abnormalitiesdalam serotonergi pathways -8 low onentrations
'8 low density o$ brain and plateletserotonin transporters
>8 a high density o$ brainand platelet
serotonin binding sites= and ?8 a low onentration o$ tryptophan
whih is used in serotonin synthesis3