LDL transports cholesterol to cells

HDL transports cholesterol to liver

LDL + cholesterol can form thrombus = clot

Hemorheologic–hemodynamic theory:

Slowed blood flow = mechanism for cholesterol buildup on arterial walls

Acute Myocardial Infarction (AMI)Delivery of oxygen by the coronary arteries

LESS THAN

Oxygen demand of the myocardial cell

~ 200-250 ml/min

Excercising

200 ml/minRest

Exercise 1000 ml/min~ 1000 ml/min

NORMAL

Myocardium uses > 75% of oxygen delivered to it!!!!!!!

Acute Myocardial Infarction (AMI)Delivery of oxygen by the coronary arteries

LESS THAN

Oxygen demand of the myocardial cell

~ 200-250 ml/min

Blockage of coronary = reduced flow….but there is no margin for reduced flow

Excercising

200 ml/minRest

Exercise 1000 ml/min~ 1000 ml/min

NORMALClots & Narrowing

Reduce Flow

Ischemic Cycling