1
Rapid Response Radiotherapy Program (RRRP)
And Bone Metastases Site Group Clinic (BMC)
Annual Report
January–December 2010
Dr. Edward Chow Chair
Ms. Lori Holden Vice-Chair
Rapid Response Radiotherapy Program and Bone Metastases Site Group
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Executive Summary
On behalf of the Rapid Response Radiotherapy Program and the Bone Metastases Site Group
(RRRP/BMC), we are pleased to send you our 2010 annual report.
1. Clinics a) RRRP clinics: The number of patients seen annually in the five weekly half-day clinics
has reached a plateau of 500-600, eighty percent of which are new to OCC.
b) We have an advanced practice radiation therapist with the support of the Ministry of
Health (MOH).
2. Education a) Newsletter - Our readers indicated they found our quarterly newsletter HOT SPOT
informative and educational.
b) We continue to offer electives to palliative health care professionals from all over the
world to visit our Centre and learn about our programs.
c) We have a full time RRRP fellow
3. Research a) We were successful in obtaining grant support both from peer reviewed granting
agencies and industries to continue our research projects.
b) The publications and presentations from our members continue to be outstanding.
We have published 2 books titled: 1) Bone and Brain Metastases: Advances in
Research and Treatment and 2) Advanced Cancer. Pain and Quality of Life c) Research students from Waterloo‘s co-op program have been extremely productive,
have also won numerous awards and have been successfully accepted to medical
schools and graduate degrees
4. Awards Ms. Gunita Mitera (RRRP Therapist in clinic 2008 – 2010)
2010 University of Toronto PhD Scholarship for 5 years
Ms. Lori Holden (RRRP/BMC Vice-Chair and RRRP Advanced Practice Radiation
Therapist)
2010 Schulich Award for Nursing & Clinical Excellence
Dr. Edward Chow
2010 Outstanding Leadership Award, Ontario Palliative Care Association
2010 Best Annual Research Performance Award, Department of Radiation Oncology,
University of Toronto
Dr. Andrea Donovan
2010 Career Development Award, Department of Medical Imaging, University of Toronto
2010 E.L. Lansdown Award for Best Teacher in Residency Program, Department of
Medical Imaging, University of Toronto
2010 Outstanding Teacher in the Residency Program Award, Department Medical
Imaging, University of Toronto
2010 Dean‘s Fund New Staff Award, University of Toronto
2010 American Roentgen Ray Society Clinician Educator Development Program
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2010 Outstanding Poster Award (2nd place), 2010 Canadian Association of Radiologists
Meeting
Poster title: ―Hip Arthroplasty Hardware and Complications‖
Dr. Urban Emmenegger
2010 Prostate Cancer Canada (PCC) Clinician-Scientist Award
2010 Canadian Cancer Society Research Institute (CCSRI) Junior Grant Panel Travel
Award
Ontario Institute for Cancer Research (OICR) Clinician-Scientist II Investigator Award
Dr. Arjun Sahgal
2010 Postgraduate Mentorship Award, Department of Radiation Oncology, University of
Toronto
Dr. May Tsao
2010 Excellence in Post-graduate Medical Education, Department of Radiation Oncology,
University of Toronto
5. Our Quality Assurance rounds resulted in several published case reports.
This report summarizes our very successful year and the academic activities of the RRRP/BMC.
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Odette Cancer Centre Rapid Response Radiotherapy Program (RRRP)
2010
The membership of the RRRP currently includes:
Radiation Oncologists
Edward Chow (Chair)
Toni Barnes
Cyril Danjoux
Arjun Sahgal
May Tsao
Kristopher Dennis (Fellow)
Radiation Therapists
Lori Holden (Vice-Chair)
Florencia Jon
Nurses
Matina Floros
Maryon Walter
Ernest Dixon
Michelle Ross
Jennifer Smith
Pharmacists
Carlo DeAngelis
Mark Pasetka
Medical Physicist
Gordon Chan
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Odette Cancer Centre Bone Metastases Site Group
2010
The membership of the BMC currently includes:
Radiation Oncologists Radiation Therapists
Edward Chow (Chair) Lori Holden (Vice-Chair)
Toni Barnes Florencia Jon
Cyril Danjoux
Arjun Sahgal Nurses
May Tsao Macey Farhadian
Kristopher Dennis (Fellow) Sima Farhangi-Manesh
Orthopedic Surgeons Pharmacists
Joel Finkelstein Carlo DeAngelis
Michael Ford Mark Pasetka
Albert Yee
Medical Physicist
Radiologists Gordon Chan
Monique Christakis
Andrea Donovan
Linda Probyn
Robyn Pugash
Joel Rubenstein
Medical Oncologist
Urban Emmenegger
Palliative Care Physician
Paolo Mazzotta
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EDUCATION
The RRRP publishes a quarterly newsletter ―HOT SPOT‖ and provides educational electives for
students and health care professionals interested in palliative radiotherapy.
Hot Spot Newsletter
In response to a satisfaction survey from our referring physicians who wanted better
communication, we initiated a quarterly newsletter in 1999 called ―HOT SPOT‖.
HOT SPOT is the educational newsletter of the RRRP at OCC. It is published quarterly and
distributed to oncologists, palliative care specialists, family doctors and professional health care
workers in palliative medicine. Our readership has expanded to over 2,000 per issue and we
continue to expand our circulation to new readers. Survey results from our readers rated the
educational value of HOT SPOT as high and suggested that we add other topics of interest. We
increased the content of our newsletter from four to six pages with additional sections and
contributors. The newsletter has regular articles on the following topics:
ETHICS
RESEARCH
PSYCHOSOCIAL
ADVICE FROM PHARMACIST
EDUCATIONAL ACTIVITIES
EDUCATIONAL INSERT
Each issue also has a double-sided educational insert.
The Editorial Board of Hot Spot
Founders Drs. L. Andersson and C. Danjoux
Editor Dr. E. Chow
Associate Editor Dr. C. Danjoux
Consultant Dr. S. Wong
Advisers Dr. E. Barnes, Dr. R. Goldman, Dr. A. Husain, Dr. L. Librach,
Ms. F. Jon, Dr. A. Sahgal, Ms. L. Holden, Dr. E. Szumacher,
Dr. M. Tsao
Editorial & Financial Manager Ms. S. Yuen
The publication of the newsletter is made possible by the financial support of pharmaceutical &
radiotherapy equipment companies.
The newsletter is also available electronically on the OCC web site:
http://www.sunnybrook.ca/content/?page=2341.
[Appendix E provides the content of previous issues and inserts of HOT SPOT from
1999-2010.]
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Educational Electives
As part of our undergraduate teaching, students from the co-op program at the University of
Waterloo have their electives working with the RRRP-BMC. This co-operative educational elective has
been extremely successful.
Awards
Philiz Goh (in clinic 2006 - 2008), nursing graduate student.
2010 Lippincott Williams & Wilkins (LWW) Nursing Poster Presentation Award
2010 University of Toronto Faculty of Nursing Gordon Cressy Student Leadership Award
2010 University of Toronto Student‘s Administrative Council Undergraduate Grant
2010 Clinical Practice and Education Poster Presentation Award, 16th International
Conference on Cancer Nursing
2010 Education Award for Nursing Student, Nursing Leadership Network of Ontario
2010 Johnson & Johnson National Leadership Award
Candi Flynn (in clinic 2007 – 2008)
2010 Have A Heart Bursary Program Award, Canadian Cardiovascular Society Academy
Stephanie Hadi (in clinic 2007 - 2008), undergraduate student.
2010 Ontario Graduate Scholarship
Kristin Harris (in clinic 2005 – 2006), medical student.
2010 Mary L. Cassidy Award, University of Toronto Faculty of Medicine
Sarah Campos (in clinic 2008), undergraduate student.
2010 ‗Proudly She Marched‘ Jocelyn Cowan Scholarship, University of Waterloo
Nadia Salvo (in clinic 2008 - 2009), graduate student.
2010 Ontario Graduate Scholarship
[Appendix F – Undergraduate Teaching–Co-op Program]
Health Care Professionals Electives
The RRRP provides an orientation for other health care professionals to experience the activities of
the RRRP clinics. Drs. Angela van Baardwijk from the Netherlands and Professor Ben Corn from Israel
spent a couple of days with us as they plan to start a similar project in their Centre. Other visitors
include: Ms. Krista McGrath and Ms. Susan Loveland (radiation therapists) from Credit Valley (Carlo
Fidani) Centre, Mississauga, Ontario. They found the experience valuable and recommend it for
others planning to start a similar program.
Medical student observers: Drs. Tali Bogler, Amy Glicksman, Punam Rana, Michele Leigh, Daniel
Toguri, Meagan Doyle, Nafisha Lalani, Kedar Patil
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RESEARCH
The RRRP/BMC team objective is to provide palliative radiotherapy in an academic environment.
We participate in local, national and international clinical trials, have regular research rounds and
have been successful in securing grants to fund our research projects.
Clinical Trials
We participate in several clinical trials. The research students have been an essential resource in
helping us to enroll, follow-up, analyze and publish our studies. Without the dedication of our
research students, it would have been difficult to successfully complete our research studies.
[Appendix G - A list of ongoing research studies in the RRRP and BMC]
CPROG (Canadian Palliative Radiation Oncology Group)
Our collaboration with Princess Margaret Hospital (PMH) and the Hamilton Regional Cancer Centre
Palliation Radiation Oncology Group, led to the formation of the Palliative Radiotherapy Oncology
Group Ontario (PROG-O) in 2000. Since then PROG-O has expanded to include Cancer Centres
from the Maritimes, Manitoba, Calgary and British Columbia. Currently, this group meets monthly
through videoconference. This has improved communication between the staff involved in the
palliative radiotherapy program in those Centres and offered the opportunity for collaboration in
research. At the last CARO meeting, more Cancer Centres expressed enthusiasm in participating in
PROG-O rounds.
PROG-O offers a national forum for monthly research discussion in palliative radiotherapy. Over the
past years the coordinators for the PROG-O rounds have been Drs. J. Wu, A. Bezjak, R. Wong and
T. Barnes. The rounds are scheduled for the first Tuesday of every month.
To represent the change in participation from Ontario to Cancer Centres across Canada we
renamed the group as Canadian Palliative Radiation Oncology Group (CPROG)
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Videoconference Rounds (CPROG)
The subjects discussed during 2010 were:
2010 Title Presenter(s)
January 12 Impact of 2D vs 3D radiotherapy planning for patients
with bone metastases – A prospective study
Dr. Kathy Pope, PMH
February 2 Improving functional outcomes with dose-escalated
irradiation for malignant spinal cord compression
Dr. Siddhartha Baxi,
PMH
March 2 Development of a quality of life (QOL) module for
malignant spinal cord compression (MSCC): Four phases
to international validation
Ms. Gunita Mitera,
OCC
April 13 Palliative radiation therapy and the C.S.R.T in the
Capital
Ms. Sharon Seed,
Ottawa
May 4 a) Neuropathic pain: The case of a critical statistical
error detected by a manuscript reviewer
b) Complicated or uncomplicated bone pain? A look at
bone metastases morphology using routine CT
imaging
a) Dr. Jackson Wu,
TBCC Calgary
b) Dr. Melanie
Gaudreault, TBCC
Calgary
June 1 Palliative treatment of painful bone metastases with MRI
guided high intensity focused ultrasound (MRIgFUS)
Drs. Sangeet Ghai
and Walter
Kucharczyk, UHN
October 5 Test connection session
Dr. Rebecca Wong,
PMH
November 23 Statins – Do they have a role in the management of
radiation late effects and, by extension, retreatments?
Dr. Wilfred Levin,
PMH
December 21 Case reports a) Dr. Jackson Wu,
TBCC Calgary
b) Dr. Rebecca
Wong, PMH
*Rounds cancelled: July 6, August 3, September 7
RRRP and BMC Monthly Meetings
The subjects discussed during 2010 were:
2010 Title Presenter(s)
January 5 Research Projects
(Chaired by Dr. Edward Chow)
Dr. Edward Chow
January 19 RRRP Quality Assurance Round
(Chaired by Dr. May Tsao)
Ms. Shaelyn Culleton,
Mr. Liang Zeng, Dr.
Gordon Chan
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February 2 RRRP Presentation – A needs assessment of the Rapid
Response Radiotherapy Program for patients receiving
palliative therapy and their caregivers
(Chaired by Ms. Gunita Mitera)
Dr. Shahmeer Ansari
February 16 Research/Education Round – Study proposal: Dose
escalation for malignant spinal cord compression
(Chaired by Ms. Gunita Mitera)
Dr. Siddhartha Baxi
March 2 RRRP Presentation – Results of 2 RRRP Studies
(Chaired by Ms. Lori Holden)
Ms. Gunita Mitera
April 6 RRRP Presentation – Abstract presentations for the
upcoming palliative conference
(Chaired by Ms. Gunita Mitera)
Ms. Gunita Mitera,
Ms. Shaelyn Culleton,
Mr. Liang Zeng,
Mr. Martin Leung,
Drs. Amanda Caissie
and Eman Al-Duhaiby
May 4 RRRP Presentation – Update on the development of the
EORTC bone, brain and SCC modules
(Chaired by Ms. Florencia Jon)
Ms. Lori Holden
May 18 RRRP Quality Assurance Round
(Chaired by Dr. May Tsao)
Ms. Florencia Jon,
Mr. Justin Kwong,
Ms. Cassandra Uy,
Mr. Martin Leung
June 1 RRRP Presentation – Radiotherapy at MAASTRO clinic,
the Netherlands
(Chaired by Ms. Florencia Jon)
Dr. Angela van
Baardwijk
July 6 RRRP Presentation – Palliative radiation oncology as an
evolving subspecialty; from DNR to basic science
(Chaired by Dr. Edward Chow)
Dr. Amanda Caissie
July 20 RRRP Presentation – Skeletal care in cancer
(Chaired by Ms. Lori Holden)
Dr. Benjamin Ofori
August 3 RRRP Presentation – Oxygen Therapy: How is it
ordered, funded, and provided for in the community
(Chaired by Ms. Florencia Jon)
Ms. Dianne Naiman
September 7 RRRP Presentation – Prevention and management of
constipation in cancer patients
(Chaired by Ms. Florencia Jon)
Dr. Carlo DeAngelis
September 21 RRRP Presentation – Breakthrough cancer pain – A
thorn by any other name would hurt as much
(Chaired by Ms. Lori Holden)
Dr. Carlo DeAngelis
October 5 RRRP/BMC Annual General Meeting
(Chaired by Dr. Edward Chow)
All
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October 19 RRRP Quality Assurance Round
(Chaired by Dr. May Tsao)
Drs. Urban
Emmenegger and
Kristopher Dennis
November 2 RRRP Research Meeting – Discuss research projects on
home oxygen therapy, SOB and LC 13, fatigue and lung
patient preference study
(Chaired by Dr. Edward Chow)
Ms. Kaitlin Koo and
Mr. Liang Zeng
November 16 Research/Education Round – Home oxygen therapy
(Chaired by Ms. Lori Holden)
Ms. Kaitlin Koo and
Mr. Liang Zeng
December 7 RRRP Presentation – a) Magnetic resonance-guided high
intensity focused ultrasound for palliation of
painful skeletal metastases - A pilot study
b) Cementoplasty presentation
(Chaired by Ms. Lori Holden)
a) Drs. Gregory
Czarnota and
Kristopher Dennis
b) Dr. Robyn Pugash
*Rounds cancelled: March 16, April 20, June 15, August 17, December 21
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Grants "Bone Tape": Development of a novel method for stabilizing traumatic craniofacial injuries.
Congressionally Directed Medical Research Program $144,300 (2010 - 2011). Whyne CM,
Fialkov J, Regev E, Santerre P.
A phase I trial on the use of PDT in the treatment of breast cancer vertebral metastasis.
Canadian Breast Cancer Foundation $300,850 (2009 – 2012). Yee A, Whyne C, Akens M,
Sahgal A, Chow E, Wilson B, Bisland S, Clemons M.
A phase II study of maintenance therapy with Temsirolimus in androgen-independent
prostate cancer after first-line chemotherapy with Docetaxel. Wyeth Pharmaceuticals Canada
Inc. $315,000 (2007 – present). Emmenegger U.
A pilot study to evaluate urinary markers of pain flare in patients undergoing external beam
radiotherapy for the treatment of painful bone metastases. International Society of Oncology
Pharmacy Practitioners. $15,000 Euros (2010). DeAngelis C, Chow E, Pasetka M, Walker S.
Bone stability and tumor burden in the metastatic spine: implications of variable disease
patterns. Canadian Institute of Health Research $379,862 (2008 - 2012). Whyne C, Yee AJ,
Finkelstein JA.
Centre for Research in Image-Guided Therapeutics. Canada Foundation for Innovation,
Research Hospital Fund Large Scale Institutional Endeavours $14,337,919 (2008 - 2011).
Hynynen, K, multiple collaborators including Whyne C.
Development of a Canadian-led international bone metastases module to accompany
European Organization for Research and Treatment of Cancer Quality of Life Group Core
Questionnaire (the EORTC QLQ-C30) for future clinical trials in patients with bone metastases.
Phase IV study. EORTC Quality of Life Group Grant $74,000 Euro (2010). Chow E.
Enhancing the application of health-related quality of life evaluations for guiding clinical care:
An Examination of changes in appraisal in lumbar degenerative disease patients before and
after surgical intervention. PSI Foundation $59,000 (2009 - 2011). Finkelstein J.
Finite Element Modelling of The Human Craniofacial Skeleton. Advanced cranio-maxillofacial
forum research grant $60,000 (2009 - 2011). Fialkov J, Whyne CM.
Hypoxia: a mediator of PSA surge in prostate cancer patients undergoing antiangiogenic
therapy? University of Toronto Dean‘s Fund. $10,000 (2009 – 2014). Emmenegger U.
Improving emergent care for bone health in vertebral disease - knowledge translation
through ethnographic study of access, triage, and care delivery. Canadian Institute of Health
Research: Catalyst Grant in Bone Health. $10,000 (2010 - 2011). Webster F, Yee AJ,
Fehlings MG, Kreder HK, Gagliardi A.
Metastatic breast cancer genome anatomy. Canadian Breast Cancer Research Alliance,
Special Competition in New Approaches to Metastatic Disease in Breast Cancer Research
$750,000 (2005 - 2010). Seth A, Aubin J, Kahn H, Lyons-Weiler J, Yee AJ, Narod S.
Metronomic chemotherapy in castration-resistant prostate cancer: Overcoming treatment
resistance. Prostate Cancer Canada $300.000 (2010 – 2012). Emmenegger U.
Modeling thin bone structures of the human skeleton. Natural Sciences and Engineering
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Research Council (NSERC) $165,000 (2006 - 2011). Whyne C.
Photodynamic therapy treatment to enhance fracture healing. Congressionally Directed
Medical Research Program $144,300 (2010 - 2011). Akens MK, Whyne CM, Nam D, Wilson
BC, Yee AJM.
Photodynamic therapy treatment to enhance fracture healing. US Army Department of
Defense DOD Peer Reviewed Orthopaedic Research Program, Research Program of the
Congressionally Directed Medical Research Programs (CDMRP). $100,000 (2010 - 2011).
Akens M, Whyne C, Yee A, Nam D, Wilson B.
Studying the role of macro-autophagy in mediating response to antiangiogenic tumor
therapy. Canada Foundation for Innovation Leaders Opportunity Fund. $90,000 (2010).
Emmenegger U.
The impact of photodynamic therapy for the biomechanical stability of the metastatic spine:
characterization independent and combined treatment effects with bisphosphonates and
radiation therapy. Ontario Institute for Cancer Research $530,361 (2008 - 2011). Whyne C,
Yee AJ, Wilson BC, Burch S, Bisland S.
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Publications Akens MK, Hardisty MR, Wilson BC, Schwock J, Whyne CM, Burch S, Yee AJ. Defining the
therapeutic window of vertebral photodynamic therapy in a murine pre-clinical model of
breast cancer metastasis using the photosensitizer BPD-MA (Verteporfin). Breast Cancer
Research and Treatment 119: 325-333, 2010.
Al Duhaiby E, Pang J, Kwok S, Chow E. Predictive models for survival in patients with
advanced cancer. The Asia-Pacific Journal of Oncology & Hematology (APJOH) (published
online January 2, 2010).
Amemiya Y, Wang W, Benatar T, Nofech-Mozes S, Yee AJ, Kahn H, Holloway C, Seth A.
Insulin like growth factor binding protein-7 reduces growth of human breast cancer cells and
xenografted tumors. Breast Cancer Research and Treatment (published online May 13,
2010).
Barnes EA, Chow E, Tsao M, Bradley NM, Doyle M, Li K, Lam K, Danjoux C. Physician's
expectation of treatment outcomes for patients with brain metastases referred for whole
brain radiotherapy. International Journal of Radiation Oncology, Biology and Physics 76(1):
187-192, 2010.
Bedi H, Hird A, Campos S, Chow E. Symptom Clusters in Metastatic Cancer - A Critical
Appraisal. Journal of Pain Management 3(1): 17-30, 2010.
Bedi H, Kwong J, Chow E. Metastatic cancer: Symptom cluster and gender differences
research in patients with metastatic cancer. Journal of Alternative Medicine Research 2(3):
285-295, 2010.
Bedi H, Presutti R, Hird A, Campos S, Zhang L, Mitera G, Sinclair E, Barnes E, Tsao M, Sahgal
A, Danjoux C, DeAngelis C, Chow E. Gender difference in the Edmonton Symptom
Assessment System (ESAS) scores in patients with advanced cancer. Journal of Pain
Management 3(1): 63-72, 2010.
Campos S, Zhang L, Salvo N, Hird A, Tsao M, Barnes E, Danjoux C, Sahgal A, Mitera G,
Sinclair E, Nguyen J, Napolskikh J, Chow E. Elderly patients with painful bone metastases
should be offered palliative radiotherapy. International Journal of Radiation Oncology, Biology
and Physics 76(5): 1500-1506, 2010.
Campos S, Zhang L, Sinclair E, Tsao M, Barnes E, Danjoux C, Sahgal A, Goh P, Culleton S,
Mitera G, Chow E. The palliative performance scale: Examining its correlation to Karnofsky
Performance Scale in an outpatient palliative radiation oncology clinic. Journal of Pain
Management 3(1): 89-97, 2010.
Chow E, Hruby G, Harris K, Enright K, Sinclair E, Chan G. Determining the accuracy of health
care professionals in predicting the survival of patients with advanced metastatic cancer.
Journal of Pain Management 3(1): 73-80, 2010.
Chow E, James J, Barsevick A, Hartsell W, Ratcliffe S, Scarantino C, Ivker R, Roach M, Suh J,
Petersen I, Konski A, Demas W, Bruner D. Functional interference clusters in cancer patients
with bone metastases: A secondary analysis of RTOG 9714. International Journal of Radiation
Oncology, Biology and Physics 76(5): 1507-1511, 2010.
Chow E, Schofeld P, Rosenbluth R, Merrick J. Advanced cancer and pain. Journal of Pain
Management 3(1): 3, 2010.
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Culleton S, Kwok S, Chow E. Radiotherapy for pain. Clinical Oncology (published online
December 17, 2010).
D‘Alimonte L, Sinclair E, Seed S. Orthovoltage energies for palliative care in the 21st century:
Is there a need? Radiography (published on October 13, 2010).
Dennis K, Wong K, Jon F, Kwong J, Chow E. Benign myelomalacia mimicking malignant spinal
cord compression in a patient with metastatic non-small cell lung carcinoma: A case report.
International Journal on Disability and Human Development 9(1): 77–79, 2010.
Donovan A, Rosenberg ZS, Cavalcanti CF. MR imaging of peripheral entrapment neuropathies,
Part II: The knee, leg, ankle and foot. RadioGraphics Radiographics 30(4): 1001-1019, 2010.
Donovan A, Rosenberg ZS. Current concepts in MR imaging of ankle and lateral hindfoot
impingement syndromes. American Journal of Roentgenology 195(3): 595-604, 2010.
Donovan A. Radiology residents as teachers: Current status of teaching skills training in US
residency programs. Academic Radiology 17(7): 928-933, 2010.
Finkelstein JA, Razmjou H, Schwartz CE. Response shift outcome assessment in orthopaedic
surgery: is there a difference between complete and partial treatment? Journal of Clinical
Epidemiology 62(11): 1189-90, 2010.
Hardisty MR, Akens M, Yee AJ, Whyne CM. Image registration demonstrates the growth plate
has a variable affect on vertebral strain. Annals of Biomedical Engineering 38(9): 2948-2955,
2010.
Hird A, Culleton S, Chow E. Cancer-related bone pain. Editor: Andrew Davis. Oxford
University Press. European Journal of Cancer Care 19 (4): e7, 2010.
Hird A, Wong J, Zhang L, Tsao M, Barnes E, Danjoux C, Chow E. Exploration of symptoms
clusters within cancer patients with brain metastases using the Spitzer Quality of Life Index.
Supportive Care in Cancer 18(3): 335-342, 2010.
Hojjat SP, Hardisty MR, Whyne CM. Micro CT based highly-automated 3D segmentation of the
rat spine for quantitative analysis of metastatic disease. Journal of Neurosurgery: Spine
13(3): 367-370, 2010.
Hrabchak C, Rouleau J, Moss I, Woodhouse K, Akens M, Bellingham C, Keeley F, Yee AJ.
Evaluation of genipin cross-linked elastin-like polypeptides in the treatment of osteochongral
defects of the knee in rabbits. Acta Biomaterialia 6(6): 2108-2115, 2010.
James T, Holden L, Laura D‘Alimonte L. A retrospective review of the effect of foot
immobilization on isocentre shifts for the treatment of prostate cancer. Canadian Journal of
Medical Radiation Technology 41(1): 20-24, 2010.
Johnson C, Fitzsimmons D, Gilbert J, Arrarras JI, Hammerlid E, Bredart A, Ozmen M,
Dilektasli E, Coolbrandt A, Kenis C, Young T, Chow E, Venkitaraman R, Howse F, George S,
O‘Connor S, Yadegarfar G on behalf of the EORTC Quality of Life Group. Development of the
European Organisation for Research and Treatment of Cancer quality of life questionnaire
module for older people with cancer: The EORTC QLQ-ELD15. European Journal of Cancer 46:
2242-2252, 2010.
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Joseph K, Tai P, Wu J, Barnes E, Levin W. Workshop report: a practical approach and
general principles of re-irradiation for in-field cancer recurrence. Clinical Oncology (published
online September 29, 2010).
Khoury A, Beyth S, Mosheiff R, Joskowicz L, Finkelstein J, Liebergall M. Computer-assisted
orthopaedic fracture reduction: clinical evaluation of a software prototype. Current
Orthopaedic Practice (published online October 26, 2010).
Lo S, Holden L, Lutz S, Liu R, Chow E. Should all patients with uncomplicated bone
metastases be treated with a single 8 Gy fraction? Expert Review of Pharmacoeconomics &
Outcomes Research 10 (2): 95-98, 2010.
Lo SS, Sahgal A, Wang JZ, Mayr NA, Sloan AE, Mendel E, Chang E. Stereotactic body
radiotherapy for spine metastases. Discovery Medicine 9(47): 289-296, 2010.
Lotan R, Al-Rashdi A, Yee A, Finkelstein J. Clinical features of conjoined lumbosacral nerve
roots versus lumbar intervertebral disc herniations. European Spine Journal 19(7): 1094-
1098, 2010.
Lubovsky O, Wright D, Hardisty M, KissA, Dreder HJ, Whyne C. Importance of the dome and
posterior wall as evidenced by bone density mapping in the acetabulum. Clinical
Biomechanics (published online November 24, 2010).
Lutz S, Korytko T, Nguyen J, Khan L, Chow E, Corn B. Palliative radiotherapy: When is it
worth it and when is it not? The Cancer Journal: The Journal of Principles & Practice of
Oncology 16 (5): 473-482, 2010.
Lutz S, Lo S, Chow E, Sahgal A, Hoskin P. Radiotherapy for metastatic bone disease: Current
standards and future prospectus. Expert Review of Anticancer Therapy 10(5): 683-695, 2010.
Ma L, Sahgal A, Chuang C, Descovich M, Petti P, Smith V, Verhey L, Barbaro N, McDermott M,
Huang K, Nakamura J, Sneed P, Larson D. Functional relationship between the volume of a
near-target peripheral isodose line and its isodose value for gamma knife radiosurgery.
Radiosurgery 7: 75-83, 2010.
Ma L, Sahgal A, Cozzi L, Chang E, Shiu A, Letourneau D, Yin F, Fogliata A, Kaissl W, Hyde D,
Laperriere NJ, Shrieve DC, Larson DA. Apparatus-dependent differences in spine stereotactic
body radiotherapy (SBRT) dosimetry. Technology in Cancer Research and Treatment 9(6):
563-574, 2010.
Ma L, Sahgal A, Descovich M, Cho Y, Chuang C, Huang K, Laperriere N, Shrieve D, Larson D.
Equivalence in dose fall-off for isocentric and non-isocentric intracranial treatment modalities
and its impact on dose fractionations schemes. International Journal of Radiation Oncology,
Biology and Physics 76(3): 943-948, 2010.
Ma L, Sahgal A, Larson D. Letter to the editor. Technology in Cancer Research and Treatment
9(4): 317, 2010.
Maloul A, Fialkov J, Hojjat SP, Whyne CM. A technique for the quantification of the 3D
connectivity of thin articulations in bony sutures. Journal of Biomechanics 43: 1227-1230,
2010.
Mitera G, Chan G, Mah K, Law R, DeAngelis C, Dent R, Chow E. A rare adverse skin reaction
after a single 8Gy of radiation therapy to the thoracic spine: A case report and review of the
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literature. Current Oncology 17(5): 70-73, 2010.
Mitera G, Fairchild A, DeAngelis C, Emmenegger U, Zurawel-Balaura L, Zhang L, Bezjak A,
Levin W, Mclean M, Zeiadin N, Pang J, Nguyen J, Sinclair E, Chow E, Wong R. A multi-centre
assessment of the adequacy of cancer pain treatment using the Pain Management Index.
Journal of Palliative Medicine 13(5): 589-593, 2010.
Mitera G, Fairchild A. Cancer pain and under-medication. Journal of Alternative Medicine
Research 2(3): 345-355, 2010.
Mitera G, Probyn L, Ford M, Donovan A, Rubenstein J, Finkelstein J, Christakis M, Zhang L,
Campos S, Culleton S, Nguyen J, Sahgal A, Barnes E, Tsao M, Danjoux C, Holden L, Yee A,
Khan L, Chow E. Correlation of computed tomography imaging features with pain response in
patients with spine metastases after radiation therapy. International Journal of Radiation
Oncology, Biology and Physics (published online October 1, 2010).
Mitera G, Zeiadin N, Kirou-Mauro A, DeAngelis C, Wong J, Sanjeevan T, Sinclair E,
Danjoux C, Barnes E, Tsao M, Sahgal A, Chow E. Retrospective assessment of cancer pain
management in an outpatient palliative radiotherapy clinic using the pain management
index. Journal of Pain and Symptom Management 39(2): 259-267, 2010.
Mitera G, Zeiadin N, Sahgal A, Finkelstein J, Chow E, Loblaw A. Quality of life measures used
in radiation therapy trials for patients with metastatic spinal cord compression (MSCC): A
literature review. Journal of Pain Management 3(1): 31-38, 2010.
Myers J, Gardiner K, Harris K, Lilien T, Bennett M, Chow E, Selby D, Zhang L. Evaluating
correlation and inter-rater reliability for four performance scales in the palliative care setting.
Journal of Pain and Symptom Management 39(2): 250-258, 2010.
Nguyen J, Sahgal A, Chow E, Danielson B. Brain metastases and quality of life. Journal of
Alternative Medicine Research 2(3): 257-272, 2010.
Olsen M, Davis ET, Whyne CM, Zdero R, Schemitsch EH. The biomechanical consequence of
insufficient femoral component lateralization and exposed cancellous bone in hip resurfacing
arthroplasty. Journal of Biomedical Engineering 132: 081011, 2010.
Pang J, Panzarella T, Chow E. Prognosis and survival prediction. Journal of Alternative
Medicine Research 2(3): 309-332, 2010.
Peleg E, Beek M, Joskowicz L, Liebergall M, Mosheiff R, Whyne CM. Patient specific
quantitative analysis of fracture fixation in the proximal femur implementing principal strain
ratios. Method and experimental validation. Journal of Biomechanics 43(14): 2684-2688,
2010.
Presutti R, Zhang L, Tsao M, Barnes E, Danjoux C, Sahgal A, Mitera G, Sinclair E, Chow E.
Projected referral for health care services in an out-patient palliative radiotherapy clinic.
Journal of Pain Management 3(1): 81-88, 2010.
Roberge D, Menard C, Bauman G, Chan A, Mulroy L, Sahgal A, Malone S, McKenzie M,
Schroeder G, Fortin M, Ebacher A, Milosevic M. Radiosurgery scope of practice in Canada: A
report of the Canadian association of radiation oncology (CARO) advisory committee.
Radiotherapy and Oncology 95(1): 122-128, 2010.
Ruschin M, Nayebi N, Carlsson P, Tamerou M, Li W, Laperriere N, Sahgal A, Menard C, Jaffray
18
D. Performance of a novel repositioning head frame for gamma knife perfexion and image
guided linac-based intracranial stereotactic radiotherapy. International Journal of Radiation
Oncology, Biology and Physics 78(1): 306-313, 2010.
Sahgal A, Barani IJ, Novotny J, Zhang B, Petti P, Larson DA, Ma L. Prescription dose
guidelines based on physical criterion for multiple metastatic brain tumors treated with
stereotactic radiosurgery (SRS). International Journal of Radiation Oncology, Biology and
Physics 78(2):605-608, 2010.
Sahgal A, Chow E, Holden L, Merrick J. Understanding the patient. Journal of Alternative
Medicine Research 2(3): 253, 2010.
Sahgal A, Larson D. In reply to Lo et al. International Journal of Radiation Oncology, Biology
and Physics 78(1): 314, 2010.
Sahgal A, Ma L, Chuang C, Hossain S, Petti P, Larson D, Shrieve D. Comparisons of novalis
and cyberknife spinal stereotactic body radiotherapy treatment planning based on physical
and biologic modeling parameters. Radiosurgery 7: 366-377, 2010.
Sahgal A, Ma L, Gibbs I, Gerszten PC, Ryu S, Soltys S, Weinberg V, Wong S, Chang E, Fowler
J, Larson DA. Spinal cord tolerance for stereotactic body radiotherapy. International Journal
of Radiation Oncology, Biology and Physics 77(2): 548-553, 2010.
Sahgal A, Ma L, Weinberg V, Gibbs IC, Chao S, Chang U, Werner-wasik M, Angelov A, Chang
EL, Sohn MJ, Soltys S., Letourneau D, Ryu S, Gerszten PC, Fowler J, Wong CS, Larson DA.
Re-treatment spinal cord tolerance for spine stereotactic body radiotherapy. International
Journal of Radiation Oncology, Biology and Physics (published online October 18, 2010).
Salvo N, Barnes E, van Draanen J, Stacey E, Mitera G, Breen D, Giotis A, Czarnota G, Pang J,
De Angelis C. Prophylaxis and management of acute radiation-induced skin reactions: A
systemic review of the literature. Current Oncology 17(4) 94-112, 2010.
Sanghera P, Perry J, Sahgal A, Symons S, Aviv R, Morrison M, Lam K, Davey P, Tsao M.
Definition and significance of pseudoprogression following radiotherapy with concurrent
temozolomide for glioblastoma multiforme. Canadian Journal of Neuroscience 37(1): 36-42,
2010.
Satoh T, Kobayashi K, Hori T, Iida S, Sato A, Ishiguro H, Chow E, Shimozuma K. The
European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life
Questionnaire for Japanese patients with bone metastases—The Japanese version of the
EORTC QLQ-BM22. Gan To Kagaku Ryoho 37(8): 1507-1512, 2010. (Japanese)
Sdezowski T, Whyne CM, Fialkov J. Towards characterization of craniofacial biomechanics.
Journal of Craniofacial Surgery 21: 202-207, 2010.
Selby D, Cascella A, Gardiner K, Do R, Moravan V, Myers J, Chow E. A single set of numerical
cutpoints to define moderate and severe symptoms for the Edmonton Symptom Assessment
System (ESAS). Journal of Pain and Symptom Management 39(2): 241-249, 2010.
Shiue K, Sahgal A, Chow E, Lutz S, Chang E, Mayr N, Wang J, Cavaliere R, Mendel E, Lo S.
The management of spinal cord compression from spinal metastases. Expert Review
Anticancer Therapy 10(5): 697-708, 2010.
Sigal IA, Whyne CM. Mesh morphing and response surface analysis: Quantifying sensitivity of
19
vertebral mechanical behaviour. Annals of Biomedical Engineering 38: 41-56, 2010.
Szumacher E, Barnes E. Palliative care: Patient understanding, preference and physician
communication. Journal of Alternative Medicine Research 2(3): 297-308, 2010.
Won E, Akens MK, Hardisty M, Burch S, Bisland S, Yee AJ, Wilson BC, Whyne C. Effects of
photodynamic therapy on the structural integrity of vertebral bone. Spine 35(3): 272-277,
2010.
Won E, Wise-Milestone L, Akens MK, Burch S, Yee AJ, Wilson BC, Whyne CM. Beyond
bisphosphonates: Photodynamic therapy structurally augments metastatically involved
vertebrae and destroys tumor tissue. Breast Cancer Research and Treatment 124(1): 111-
119, 2010.
Wong NS, Buckman R, Clemons M, Verma S, Dent S, Trudeau M, Roche K, Ebos J, Kerbel R,
DeBoer G, Sutherland D, Emmenegger U, Slingerland J, Gardner S, Pritchard K. Phase I-II
trial of metronomic chemotherapy with daily dalteparin and cyclophosphamide, twice weekly
methotrexate and daily prednisone (DalCMP) as therapy for metastatic breast cancer using
soluble vascular endothelial growth factor receptor levels as markers of response. Journal of
Clinical Oncology 28(5): 723-730, 2010.
20
In Press Ahn H, Singh J, Nathens A, Macdonald R, Travers A, Tallon JM, Fehlings M, Yee AJ. Pre-
Hospital Care Management of a Potential Spinal Cord Injured Patient: A Systematic Review
of the Literature and Evidence Based Guidelines. Journal of Neurotrauma.
Akens MA, Sahgal A, Yee AJ. Evaluation of photodynamic therapy as treatment for spinal
metastases. Journal of Pain Management.
Ali Zahrai, Jaskarndip Chahal, Dan Stojimirovic, Emil H. Schemitsch, Albert Yee, William
Kraemer. Quality of life and educational benefit among orthopedic surgery residents: A
prospective, multicentre comparison of the night float and the standard call systems.
Canadian Journal of Surgery.
Ang Lee, Peng Chun, Deng Zhaoqun, Sze Shan, Cheng Y, Shatseva Tatiana, Yee AJ, Du
Weidong, Yang J, Yang BB. MicroRNA miR-93 promotes tumor growth and angiogenesis by
targeting integrin beta 8. Oncogene.
Bederman SS, Murnaghan O, Lansang E, Malempati H, Johnston E, Wilkinson M, Bronstein Y,
Finkelstein JA, Yee AJ. In-hospital mortality and surgical utilization in severely
polytraumatized patients with and without spinal injury. Journal of Trauma.
Bederman SS, Omoto D, Yee AJ, Kreder HJ, Finkelstein JA. How do validated measures of
functional outcome compare with commonly used outcomes in administrative database
research for lumbar spinal surgery. European Spine Journal.
Bjarnason G, Pirouzmand F, Bilbao J, Danjoux C, Sahgal A, Mitera G. Pre-operative
stereotactic body radiotherapy to a skull renal cell metastasis: An alternative to pre-operative
embolization? Journal of Palliative Medicine.
Chan E, Jon F, Holden L, Dennis K, Chow E. Pathological fracture of the tibia in a patient with
invasive ductal carcinoma of the breast: A case report of a rare finding. Journal of Pain
Management.
Cho Y, Zhang B, Bernstein M, Sahgal A. Brain metastases: gamma knife technology for
radiosurgery. Journal of Pain Management.
Choo C, Mamedov A, Chung M, Choo R, Kiss A, Danjoux C. Vitamin D insufficiency is common
in non-metastatic prostate cancer patients. Nutrition Research.
Chow E, James J, Barsevick A, Hartsell W, Ratcliffe S, Scarantino C, Ivker R, Suh J, Petersen
I, Konski A, Demas W, Bruner D. Confirmatory factor analysis of Brief Pain Inventory (BPI)
functional interference clusters in patients with bone metastases. Journal of Pain
Management.
Culleton S, Dennis K, Koo K, Zhang L, Zeng L, Kwong J, Nguyen J, Jon F, Holden L, Barnes E,
Tsao M, Danjoux C, Sahgal A, Chow E. Correlation of the Palliative Performance Scale with
the Karnofsky Performance Status in an outpatient palliative radiotherapy clinic. Journal of
Pain Management.
Culleton S, Kwok S, Chow E. Conventional radiation treatment and bone metastases. Journal
of Pain Management.
Dahele M, Fehlings M, Sahgal A. Stereotactic body radiotherapy: an emerging treatment for
patients with spinal metastases. Canadian Journal of Neuroscience.
21
Du WW, Yang BB, Shatseva TA, Yang BL, Deng Z, Shan SW, Lee DY, Seth A, Yee AJ. Versican
G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing
EGF receptor signaling. PLoS ONE.
Emmenegger U, Francia G, Chow A, Man S, Kerbel RS. Tumors that acquire resistance to low-
dose metronomic cyclophosphamide retain sensitivity to maximum tolerated dose
cyclophosphamide. Neoplasia.
Foote M, Letourneau D, Hyde D, Massicotte E, Rampersaud R, Fehlings M, Fisher C, Lewis S,
La Macchia N, Yu E, Laperriere N, Sahgal A. Stereotactic body radiotherapy for spine
metastases: technical details for practice. Journal of Clinical Neuroscience.
Jon F, Nguyen J, Rubenstein J, Holden L, Ross M, Mitera G, Dennis K, Chow E. Painful sacral
insufficiency fracture simulating metastatic disease from primary breast cancer. Journal of
Pain Management.
Kwong J, Jon F, Holden L, Zeng L, Culleton S, Danjoux X, Tsao M, Barnes T, Sahgal A, Dennis
K, Chow E. Dedicated out-patient palliative radiation treatment clinics for patients with
advanced cancer. Journal of Pain Management.
Kwong J, Jon F, Sugar L, O‘Hayon B, Holden L, Nguyen J, Ross M, Uy C, Khan L, Dennis K,
Chow E. Renal mass – primary or metastatic? The search for a definitive diagnosis. Journal of
Pain Management.
Lee DY, Jeyapalan Z, Fang L, Yang J, Zhang Y, Yee AJ, Li M, Du WW, Shatseva T, Yang BB.
Expression of Versican 3'-untranslated region modulates endogenous microRNA functions.
PLoS ONE.
Leung M, Nguyen J, Rubenstein J, Chow E, Holden L, Dennis K, Jon F. Asymptomatic 20cm-
long femoral metastasis. A unique case of long-bone disease responding to radiotherapy
alone. Journal of Pain Management.
Lutz S, Berk L, Chang E, Chow E, Hahn C, Hoskin P, Howell D, Konski A, Kachnic L, Lo S,
Sahgal A, Silverman L, von Gunten C, Mendel E, Vassil A, Bruner D, Hartsell W. Palliative
Radiotherapy for Bone Metastases: An ASTRO Evidence-Based Guideline. International
Journal of Radiation Oncology, Biology and Physics.
Ma L, Petti P, Wang B, Descovich M, Chuang C, Barani IJ, Kunwar S, Shrieve DC, Sahgal A,
Larson DA. Apparatus-dependent normal brain tissue dose with stereotactic radiosurgery of
multiple brain metastases. Journal of Neurosurgery.
Moss I, Gordon L, Woodhouse K, Whyne CM, Yee AJ. A novel thiol-modified-hyaluronan and
elastin-like polypeptide composite material for tissue engineering of the nucleus pulposus of
the intervertebral disc. Spine.
Nguyen J, Chow E, Zeng L, Zhang L, Culleton S, Holden L, Mitera G, Tsao M, Barnes E,
Danjoux C, Sahgal A. Palliative response and functional interference outcomes using the brief
pain inventory for spinal bony metastases treated with conventional radiotherapy. Clinical
Oncology.
Nguyen J, Hayter C, Wong R, Danjoux C, Holden L. A survey to assess patient awareness and
interest in hypnosis for cancer pain and distressing procedures. Journal of Alternative
Medicine Research.
22
Nguyen J, Sahgal A, Sinclair E, Mitera G, Farhadian M, Danjoux C, Finkelstein J, Yee A, Ford
M, Pugash R, Emmenegger U, Chakraborty A, Chow E. Rapid Response Radiotherapy
Program and Multidisciplinary Bone Metastases Clinic. Journal of Pain Management.
Podolsky D, Martin A, Whyne CM, Massicote E, Hardisty MR, Ginsberg H. Exploring the role of
3D simulation in surgical training: Feedback from a pilot study. Journal of Spinal Disorders &
Techniques.
Presutti R, Hird A, DeAngelis C, Fairchild A, Holt T, Loblaw A, Chow E. Palliative radiotherapy
of bone metastases and pain flare. Journal of Pain Management.
Presutti R, Nguyen J, Hird A, Fairchild A, Clemons M, Kerba M, Sahgal A, Chow E. Bone
metastases and quality of life. Journal of Pain Management.
Presutti R, Nguyen J, Holden L, DeAngelis C, Culleton S, Mitera G, Tsao M, Barnes E, Danjoux
C, Sahgal A, Salvo N, Khan L, Chow E. Radiation-induced nausea and vomiting in a palliative
radiotherapy clinic: a preliminary analysis. Journal of Pain Management.
Sahgal A, Bilsky M, Chang EL, Ma L, Yamada Y, Rhines L, Letourneau D, Foote M, Yu E,
Larson DA, Fehling M. Stereotactic body radiotherapy for spinal metastases: current status
with a focus on the application to the post-operative patient. Journal of Neurosurgery Spine.
Sahgal A, Chow E, Holden L, Merrick J. Bone metastases. Journal of Pain Management.
Sahgal A, Chow E, Holden L, Merrick J. Brain metastases. Journal of Pain Management.
Sahgal A, Massicotte E, Rampersaud R, Yee A, Fehlings M, Lewis S, Letourneau D, Hyde D,
Larson D, Ma L. Stereotactic body radiotherapy for spine tumors. Journal of Pain
Management.
Sahgal A. Spinal cord tolerance to radiation. Journal of Pain Management.
Salvo N, Doble B, Khan L, Amirthevasar G, Dennis K, Pasetka M, DeAngelis C, Tsao M, Chow
E. Prophylaxis of radiation-induced nausea and vomiting using 5-HT3 serotonin receptor
antagonists: a systematic review of randomized trials. International Journal of Radiation
Oncology, Biology and Physics.
Soliman H, Bezjak A, Sahgal A, Tsao M. Treatment of brain metastases: striving to improve
patient outcomes.
Szwedowski TD, Fialkov F, Whyne CM. Sensitivity analysis of a validated subject-specific finite
element model of the human craniofacial skeleton. Proceedings of the Institution of
Mechanical, Part H. Engineers Journal of Engineering in Medicine.
Thind AS, Strauss BH, Teitelbaum AA, Karshaffian R, Ladouceur M, Whyne CM, Goertz DE,
Foster S. A Novel Method for Measurement of Proximal Fibrous Cap Puncture Force in Chronic
Total Occlusions: The Effect of Increasing Age. Catherterization and Cardiovascular
Interventions.
Uy C, Jon F, Rosewell C, O‘Hayon B, Hanna S, Bjarnason G, Holden L, Nguyen J, Ross M,
Kwong J, Sahgal A, Khan L, Dennis K, Chow E. Suspicious perianal lesion in a patient with
renal cell carcinoma. Journal of Pain Management.
Whyne CM, Haridsty MR. Quantification of metastatic burden in the spine and its structural
implications. Journal of Pain Management.
23
Zeng L, Sahgal A, Zhang L, Koo K, Holden L, Jon F, Tsao M, Barnes E, Danjoux C, Dennis K,
Khan L, Chow E. Patterns of pain and functional improvement in patients with bone
metastases after conventional external beam radiotherapy and a telephone validation study.
Pain Research and Treatment.
Zeng L, Zhang L, Culleton S, Jon F, Holden L, Kwong J, Khan L, Tsao M, Danjoux C, Sahgal A,
Barnes E, Chow E. Edmonton Symptom Assessment Scale as a prognosticative indicator in
patients with advanced cancer. Journal of Palliative Medicine.
24
Books, Book Chapters Akens MA, Burch S, Yee AJ. Pre-clinical evaluation of photodynamic therapy as treatment for
spinal metastases. Bone and brain metastases: Advances in research and treatment. Pages
113-124. Editors: Arjun Sahgal, Edward Chow and Joav Merrick. Nova Science Publishers,
Inc. 2010.
Bedi H, Hird A, Campos S, Chow E. A critical discussion of symptom clusters in metastatic
cancer. Advanced cancer. Pain and quality of life. Chapter 12 Pages 129-144. Editors:
Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Bedi H, Kwong J, Chow E. Symptom cluster and gender differences research in patients with
metastatic cancer. Bone and brain metastases: Advances in research and treatment.
Chapter 24 Pages 357-371. Editors: Arjun Sahgal, Edward Chow and Joav Merrick. Nova
Science Publishers, Inc. 2010.
Bedi H, Presutti R, Hird A, Campos S, Zhang L, Mitera G, Sinclair E, Barnes E, Tsao M, Sahgal
A, Danjoux C, DeAngelis C, Chow E. Gender difference in patients with advanced cancer.
Advanced cancer. Pain and quality of life. Chapter 15 Pages 165-175. Editors: Edward
Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Campos S, Zhang L, Chow E. Quality of life issues in patients with bone metastases.
Advanced cancer. Pain and quality of life. Chapter 21 Pages 233-246. Editors: Edward
Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Campos S, Zhang L, Sinclair E, Tsao M, Barnes E, Danjoux C, Sahgal A, Goh P, Culleton S,
Mitera G, Chow E. Utilization of performance scale in an outpatient palliative radiation
oncology clinic. Advanced cancer. Pain and quality of life. Chapter 18 Pages 201-212.
Editors: Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Cho YB, Zhang B, Bernstein M, Sahgal A. Gamma knife technology for radiosurgery of brain
metastasis. Bone and brain metastases: Advances in research and treatment. Pages 333-347.
Editors: Arjun Sahgal, Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Chow E, Hird A, Wong, R, Zhang L, Wu J, Barbera L, Tsao M, Barnes E, Danjoux C. Meaningful
change in pain scores in the treatment of bone metastases. Advanced cancer. Pain and
quality of life. Chapter 13 Pages 145-151. Editors: Edward Chow and Joav Merrick. Nova
Science Publishers, Inc. 2010.
Chow E, Hruby G, Harris K, Enright K, Sinclair E, Chan G. Is it possible to predict the survival
of patients with advanced metastatic cancer? Advanced cancer. Pain and quality of life.
Chapter 16 Pages 177-189. Editors: Edward Chow and Joav Merrick. Nova Science
Publishers, Inc. 2010.
Chow E, Khan L, Bruland O. Radiotherapy of skeletal metastases. ASBMR Primer 8th edition
of the primer on the metabolic bone diseases and disorders of mineral metabolism. American
Society for Bone and Mineral Research (accepted for publication).
Chow E, Tsao M, Sahgal A, Barnes E, Danjoux C, Mitera G, Sinclair E. Post procedure
radiation therapy after kyphoplasty or vertebroplasty/cementoplasty for bony metastatic
disease. Advanced cancer. Pain and quality of life. Chapter 10 Pages 119-120. Editors:
Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
25
Culleton S, Hird A, Nguyen J, Emmenegger U, Verma S, Simmons C, Barnes E, Tsao M,
Sahgal A, Danjoux C, Mitera G, Sinclair E, Chow E. Bisphosphonates in combination with
radiotherapy for the treatment of bone metastases. Advanced cancer. Pain and quality of
life. Chapter 5 Pages 55-68. Editors: Edward Chow and Joav Merrick. Nova Science
Publishers, Inc. 2010.
Culleton S, Kwok S, Chow E. Conventional radiation treatment of bone metastases. Bone
and brain metastases: Advances in research and treatment. Chapter 2 Pages 27-39.
Editors: Arjun Sahgal, Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Culleton S, Pang J, Zhang L, Presutti R, Nguyen J, Mitera G, Sinclair E, Barnes E, Tsao M,
Danjoux C, Sahgal A, Chow E. Are baseline ESAS symptoms related to pain response in
patients treated with palliative radiotherapy for bone metastases? Advanced cancer. Pain
and quality of life. Chapter 6 Pages 69-76. Editors: Edward Chow and Joav Merrick. Nova
Science Publishers, Inc. 2010.
Culleton S, Zhang L, Sinclair E, Barnes E, Tsao M, Danjoux C, Campos S, Goh P, Chow E.
Improvement of symptoms following palliative radiation for bone metastases. Advanced
cancer. Pain and quality of life. Chapter 7 Pages 77-86. Editors: Edward Chow and Joav
Merrick. Nova Science Publishers, Inc. 2010.
Emmenegger U, Chow A, Bocci G. The biomodulatory capacities of low-dose metronomic
chemotherapy: complex modulation of the tumor microenvironment. The Tumor
microenvironment (TTME) Series. Pages 243-262. Editors: Reichle A. Springer-Verlag
GmbH. 2010.
Emmenegger U, Francia G, Shaked Y, Kerbel RS. Metronomic chemotherapy – principles and
lessons learnt from applications in the treatment of metastatic prostate cancer. Recent results
in cancer research. Pages 165-183. Editors: Berdel E, Kessler T, Liersch R. Springer-Verlag
GmbH. 2010.
Fairchild A, Chow E. Palliative radiotherapy. Cancer pain: assessment and management.
2nd edition. Pages 379-398. Editors: Eduardo Bruera and Russell Portenoy. Cambridge
University Press 2010.
Fairchild A, Hird A, Chow E. Pain control with palliative radiotherapy in bone metastases.
Recent advances in bone cancer progression and therapeutic approaches. Chapter 25 Pages
297-312. Editor: Dominique Heymann. Research Signpost 2010.
Flynn C, Clemons M, Zhang L, Chow E. The European Organization for Research and
Treatment of Cancer Quality-of-Life Group Bone Metastases Module (EORTC QLQ-BM22)
Questionnaire. Advanced cancer. Pain and quality of life. Chapter 20 Pages 225-232.
Editors: Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Hird A, Clemons M, Zhang L, Chow E. Skeletal related events in patients with metastatic
bone disease. Advanced cancer. Pain and quality of life. Chapter 11 Pages 123-127.
Editors: Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Hird A, Wong R, Flynn C, Hadi S, de Sa E, Zhang L, DeAngelis C, Chow E. Pain flare following
palliative radiotherapy for symptomatic bone metastases. Advanced cancer. Pain and quality
of life. Chapter 8 Pages 87-94. Editors: Edward Chow and Joav Merrick. Nova Science
Publishers, Inc. 2010.
26
Kwok S, Salvo N, Pang J, Chow E. Prognostic assessment of the cancer patient. Supportive
Oncology. Editors: Mellar P Davis, Petra Feyer, Petra Ortner, Camilla Zimmermann. Elsevier
(in press).
Lo SS, Sahgal A, Ma L, Chang EL. Advances in radiation therapy for brain metastases. Current
and future management of brain metastases. Editors: Kim and Lundsford. Karger (in press).
Lotan R, Finkelstein J. Minimally invasive surgical approaches for spine metastases. Bone and
brain metastases: Advances in research and treatment. Chapter 7 Pages 181-195. Editors:
Arjun Sahgal, Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Mitera G, Rubenstein J, Finkelstein J, Davidson M, Chow E. Remineralization of an impending
fracture from an osteolytic metastasis in a breast cancer patient from palliative radiotherapy
and bisphosphonate. A case report. Advanced cancer. Pain and quality of life. Chapter 26
Pages 287-294. Editors: Edward Chow and Joav Merrick. Nova Science Publishers, Inc.
2010.
Mitera G, Sahgal A, Laperriere N, Loblaw A. Management of malignant spinal cord
compression. Bone and brain metastases: Advances in research and treatment. Pages 55-69.
Editors: Arjun Sahgal, Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Mitera G, Zeiadin N, Sahgal A, Finkelstein J, Chow E, Loblaw A. Can we measure quality of
life for patients with metastatic spinal cord compression (MSCC)? Advanced cancer. Pain and
quality of life. Chapter 19 Pages 215-224. Editors: Edward Chow and Joav Merrick. Nova
Science Publishers, Inc. 2010.
Nguyen J, Chung M, Ford M, Goh P, Rubenstein J, Sinclair E, Mitera G, Chow E. Surgical
stabilization of severely destructive upper cervical lytic bone metastases. Advanced cancer.
Pain and quality of life. Chapter 23 Pages 263-269. Editors: Edward Chow and Joav Merrick.
Nova Science Publishers, Inc. 2010.
Nguyen J, Leung M, Presutti R, Caporusso F, Holden L, Chow E. Position of appetite and
nausea in symptom clusters in palliative radiation therapy. Handbook of nutrition and diet
and in palliative care. Taylor & Francis Group (in press).
Nguyen J, Sahgal A, Chow E, Danielson B. Quality of life in brain metastases. Bone and
brain metastases: Advances in research and treatment. Chapter 16 Pages 217-237.
Editors: Arjun Sahgal, Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Nguyen J, Sahgal A, Sinclair E, Mitera G, Farhadian M, Danjoux C, Finkelstein J, Yee A, Ford
M, Pugash R, Emmenegger U, Chakraborty A, Chow E. Innovative palliative programs: Rapid
Response Radiotherapy Program and Multidisciplinary Bone Metastases Clinic. Bone and brain
metastases: Advances in research and treatment. Chapter 1 Pages 3-25. Editors: Arjun
Sahgal, Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Nguyen J, Sinclair E, Yee A, Finkelstein J, Ford M, Chakraborty A, Farhadian M, Pugash R,
Mitera G, Danjoux C, Barnes E, Tsao M, Sahgal A, Chow E. Multidisciplinary approach to
metastatic bone disease. Advanced cancer. Pain and quality of life. Chapter 14 Pages 153-
164. Editors: Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Pang J, Jenkinson R, Mitera G, Donovan A, Pugash R, Trudeau M, Quinton C, Sinclair E,
Nguyen J, Presutti R, Chow E. Cemented hemiarthroplasty, percutaneous acetabular
cementoplasty and post-operative radiation for a high risk lesion of the hip. Advanced
cancer. Pain and quality of life. Chapter 25 Pages 279-285. Editors: Edward Chow and Joav
Merrick. Nova Science Publishers, Inc. 2010.
27
Pang J, Panzarella T, Chow E. Survival predication. Bone and brain metastases: Advances in
research and treatment. Chapter 26 Pages 389-419. Editors: Arjun Sahgal, Edward Chow
and Joav Merrick. Nova Science Publishers, Inc. 2010.
Presutti R, Campos S, Finkelstein J, Rubenstein J, Sinclair E, Mitera G, Chow E. Simple
bracing for the relief of intractable pain. Advanced cancer. Pain and quality of life. Chapter
24 Pages 271-277. Editors: Edward Chow and Joav Merrick. Nova Science Publishers, Inc.
2010.
Presutti R, Hird A, DeAngelis C, Fairchild A, Holt T, Loblaw A, Chow E. Pain flare following
palliative radiotherapy of bone metastases. Bone and brain metastases: Advances in
research and treatment. Chapter 14 Pages 181-195. Editors: Arjun Sahgal, Edward Chow
and Joav Merrick. Nova Science Publishers, Inc. 2010.
Presutti R, Nguyen J, Hird A, Fairchild A, Clemons M, Kerba M, Sahgal A, Chow E. Quality of
life research in bone metastases. Bone and brain metastases: Advances in research and
treatment. Chapter 15 Pages 197-215. Editors: Arjun Sahgal, Edward Chow and Joav
Merrick. Nova Science Publishers, Inc. 2010.
Presutti R, Zhang L, Hird A, Deyell M, Chow E. Exploring the optimal definitions of partial
response and pain progression in patients receiving radiation treatment for painful bone
metastases. Advanced cancer. Pain and quality of life. Chapter 9 Pages 95-118. Editors:
Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Presutti R, Zhang L, Tsao M, Barnes E, Danjoux C, Sahgal A, Mitera G, Sinclair E, Chow E.
Projected referral for an out-patient palliative radiotherapy clinic. Advanced cancer. Pain and
quality of life. Chapter 17 Pages 191-200. Editors: Edward Chow and Joav Merrick. Nova
Science Publishers, Inc. 2010.
Sahgal A, Massicotte E, Rampersaud R, Yee A, Fehlings M, Lewis S, Letourneau D, Hyde D,
Larson D, Ma L. Stereotactic body radiotherapy for spine tumors. Bone and brain metastases:
Advances in research and treatment. Pages 41-53. Editors: Arjun Sahgal, Edward Chow and
Joav Merrick. Nova Science Publishers, Inc. 2010.
Sahgal A, Soliman H, Larson DA. Whole brain radiotherapy of brain metastases. Current and
future management of brain metastases. Editors: Kim and Lundsford. Karger (in press).
Sahgal A, Wong CS, van der Kogel, A. Spinal cord. Radiation Injury. Pages 225-235. Editors:
Shrieve and Loeffler. Lippincott Williams and Wilkins 2010.
Sahgal, A. Clinical research in spinal cord tolerance to radiation. Bone and brain metastases:
Advances in research and treatment. Pages 135-141. Editors: Arjun Sahgal, Edward Chow
and Joav Merrick. Nova Science Publishers, Inc. 2010.
Soliman H, Bezjak A, Sahgal A, Tsao M. University of Toronto department of radiation
oncology research on the treatment of brain metastases: Striving to improve patient
outcomes. Bone and brain metastases: Advances in research and treatment. Pages 145-156.
Editors: Arjun Sahgal, Edward Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
Zhang L, Nguyen J, Hird A, Chow E. Bone metastases quality of life instrument tool.
Advanced cancer. Pain and quality of life. Chapter 22 Pages 247-259. Editors: Edward
Chow and Joav Merrick. Nova Science Publishers, Inc. 2010.
28
Posters, Presentations and Published Abstracts
10th Annual Princess Margaret Hospital Conference. Toronto, Ontario, Canada,
October 28 - 30, 2010.
Caissie A, Nguyen J, Holden L, Sahgal A, Culleton S, Zhang L, Zeng L, Tsao M, Barnes E,
Danjoux C, Dennis K, Chow E. Palliative radiation for bone metastases not only relieves
pain but also improves quality of life.
Caissie A, Zhang L, Clemons M, Fairchild A, Kerba M, Vassiliou V, Nguyen J, Sahgal A,
Culleton S, Chow E. An international study of EORTC BM22 and C15 symptom/quality of
life scores showing association with radiation response of bone metastases.
Caissie A, Zhang L, Clemons M, Fairchild A, Kerba M, Vassiliou V, Nguyen J, Sahgal A,
Culleton S, Chow E. An international study of EORTC BM22 and C15 symptom/quality of
life scores showing association with radiation response of bone metastases.
Dennis K, Wong K, Nguyen J, Culleton S, Zhang L, Holden L, Jon F, Chow E. Palliative
radiotherapy for bone metastases in the last three months of life: Worthwhile or futile?
Koo K, Culleton S, Dennis K, Zhang L, Zeng L, Kwong J, Nguyen J, Jon F, Holden L,
Barnes E, Tsao M, Danjoux C, Sahgal A, Chow E. Gender difference in symptom
presentation among patients with bone metastases.
Koo K, Culleton S, Dennis K, Zhang L, Zeng L, Kwong J, Nguyen J, Jon F, Holden L,
Barnes E, Tsao M, Danjoux C, Sahgal A, Chow E. Correlation of the palliative
performance scale with the Karnofsky performance status in a Rapid Response Palliative
Radiotherapy Outpatient Clinic.
Koo K, Zeng L, Culleton S, Dennis K, Zhang L, Caissie A, Nguyen J, Holden L, Jon F,
Tsao M, Barnes E, Danjoux C, Sahgal A, Chow E. Do elderly patients with metastatic
cancer have worse quality of life?
Sahgal A. Spine Metastases.
Zeng L, Chow E, Zhang L, Culleton S, Holden L, Tsao M, Barnes E, Danjoux C, Sahgal A.
Comparison of pain response and functional interference outcomes between spinal and
non-spinal bone metastases treated with palliative radiotherapy.
Zeng L, Chow E, Zhang L, Culleton S, Holden L, Tsao M, Barnes E, Danjoux C, Sahgal A.
Analysis of pain and interference patterns with brief pain inventory in patients with bone
metastases: A confirmatory study.
Zeng L, Salvo N, Zhang L, Leung M, Khan L, Presutti R, Nguyen J, Holden L, Culleton S,
Chow E. Predictive factors for anxiety and depression in advanced cancer patients.
Zeng L, Zhang L, Culleton S, Jon F, Holden L, Kwong J, Khan L, Tsao M, Danjoux C,
Sahgal A, Barnes E, Chow E. Edmonton symptom assessment system as a
prognosticative indicator in patients with advanced cancer.
2010 Annual Hospice Palliative Care Conference. Toronto, Ontario, Canada, April
18 – 20, 2010.
Al-Duhaiby E, Pang J, Kwok S, Chow E. Predictive models of survival for patients with
advanced cancer.
Al-Duhaiby E, Pang J, Pasetka M, DeAngelis C, Chow E, Ko Y, Barnes E, Holden L, Mitera
G, Chung H. Evaluation of a daily diary for assessing the prevalence of radiation-induced
emesis (RIE): A pilot study in progress.
Caissie A, Presutti R, Nguyen J, Holden L, Sahgal A, Culleton S, Zhang L, Zeng L, Tsao
M, Barnes E, Danjoux C, Mitera M, Chow E. Response to palliative radiation of bone
metastases associated with improved BM22 and C15 symptom and quality of life scores.
Caissie A, Presutti R, Nguyen J, Holden L, Sahgal A, Culleton S, Zhang L, Zeng L, Tsao
M, Barnes E, Danjoux C, Mitera G, Chow E. Initial BN20 and C15 symptom and quality of
life scores in patients with brain metastases.
Chow E, Caissie A, Holden L. Radiation treatment of bone metastases – biased or
evidenced based.
29
Culleton S, Presutti R, Nguyen J, Holden L, DeAngelis C, Tsao M, Barnes E, Danjoux C,
Sahgal A, Chow E. Pattern of radiation-induced nausea and vomiting in a palliative
radiotherapy clinic.
Culleton S, Presutti R, Nguyen J, Pang J, Fairchild A, Mawani A, Clemons M, Kerba M,
Yee A, Zhang L, Sahgal A, Chow E. International cross-cultural field validation of an
EORTC questionnaire module for patients with bone metastases (EORTC QLQ-BM22): A
preliminary analysis.
Holden L, Nguyen J, Hayter C, Wong R, Danjoux C, Peltier J. A survey to assess patients‘
awareness and interest in hypnosis for cancer pain and distressing procedures.
Holden L, Nguyen J, Sinclair E, Yee A, Finkelstein J, Ford M, Chakraborty A, Farhadian M,
Pugash R, Mitera G, Danjoux C, Barnes E, Tsao M, Sahgal A, Chow E. A multidisciplinary
bone metastases clinic at Sunnybrook Odette Cancer Centre: A review of the experience
from 2006-2008.
Leung M, Presutti R, Nguyen J, Zhang L, Holden L, Mitera G, Culleton S, Chow E.
Assessing baseline quality of life in patients with bone metastases using the European
Organization for Research and Treatment of Cancer Bone Metastases Module (EORTC
QLQ-BM22).
Leung M, Salvo N, Zhang L, Presutti R, Nguyen J, Holden L, Culleton S, Zeng L, Chow E.
Predictive factors for anxiety and depression in patients with advanced cancer.
Mitera G, Probyn L, Ford M, Christakis M, Donovan A, Finkelstein J, Rubenstein J, Zhang
L, Campos S, Culleton S, Nguyen J, Sahgal A, Tsao M, Barnes E, Danjoux C, Holden L,
Yee A, Chow E. Pain relief for mechanical and tumour related factors from spinal
metastases: Can we predict who will respond to palliative radiotherapy?
Mitera G, Probyn L, Ford M, Donovan A, Rubenstein J, Finkelstein J, Christakis M, Zhang
L, Campos S, Culleton S, Nguyen J, Sahgal A, Barnes E, Tsao M, Danjoux C, Holden L,
Yee A, Khan L, Chow E. Correlation of computed tomography imaging features with pain
response in patients with spine metastases following radiation therapy.
Mitera G, Zhang L, Sahgal A, Barnes E, Tsao M, Danjoux C, Holden L, Chow E. A survey
of expectations & understanding of palliative radiotherapy from patients with advanced
cancer at the Rapid Response Radiotherapy Program.
Zeng L, Nguyen J, Danielson B, Presutti R, Pang J, Clemons M, Zhang L, Sahgal A,
Holden L, Mitera G, Chow E. International validation of the European Organization for
Research and Treatment of Cancer Brain Module (EORTC-QLQ-BN20+2) for Assessing
Quality of Life in patients with brain metastases – a preliminary analysis of Canadian
Centres.
Zeng L, Presutti R, Zhang L, Tsao M, Barnes E, Danjoux C, Sahgal A, Mitera G, Sinclair
E, Chow E. Projected referral for health care services in an out-patient palliative
radiotherapy clinic.
34th ASRT Radiation Therapy Conference. San Diego, California, USA, October 31 –
November 2, 2010.
Sinclair E. Minimally invasive treatment of tumour-related vertebral compression
fractures and other metastatic bone lesions.
American Society Therapeutic Radiation Oncology. San Diego, California, USA,
October 31 – November 4, 2010.
Caissie A, Nguyen J, Holden L, Sahgal A, Culleton S, Zhang L, Zeng L, Tsao M, Barnes E,
Danjoux C, Dennis K, Chow E. Palliative radiation for bone metastases not only relieves
pain but also improves quality of life.
Jon F, Zeng L, Culleton S, Zhang L, Holden L, Tsao M, Barnes E, Sahgal A, Danjoux C,
Chow E. The Edmonton Symptom Assessment Scale (ESAS) as a prognostic indicator for
impending death in advanced cancer patients referred for palliative radiotherapy.
Khan L, Holden L, Zhang L, Culleton S, Zeng L, Jon F, Wong K, Danjoux C, Tsao M,
Sahgal A, Barnes E, Chow E. Prevalence of sleep disturbance in patients with bone
metastases attending an outpatient radiotherapy clinic.
30
Mitera G, Loblaw A, Sahgal A, Danielson B. Canadian-led international development of a
European organization for research and treatment of cancer quality of life module for
malignant spinal cord compression: results of phase I.
Pituskin E, Fairchild A, Chow E, Wu J, Presutti R, Gaudreault M, DeAngelis C, North S,
Kerba M, Venner P. Concurrent tyrosine kinase inhibitors and palliative radiotherapy in
the treatment of metastatic renal cell carcinoma: A retrospective database review.
Sahgal A, Ma L, Weinberg V, Gibbs I, Chao S, Chang U, Werner-wasik M, Fowler J, Wong
S, Larson D. Human spinal cord re-irradiation guidelines for stereotactic body
radiotherapy.
Canadian Association of Radiation Oncology Annual Meeting. Vancouver, British
Columbia, Canada, September 22 – September 25, 2010.
Caissie A, Holden L, Presutti R, Nguyen J, Culleton S, Sahgal A, Zhang L, Zeng L, Tsao
M, Barnes E, Danjoux C, Mitera G, Chow E. Symptom and quality of life post-
radiotherapy as assessed by BN20+2 and QLQ-C15-PAL in patients with brain
metastases.
Caissie A, Nguyen J, Holden L, Sahgal A, Culleton S, Zhang L, Zeng L, Tsao M, Barnes E,
Danjoux C, Dennis K, Chow E. Palliative radiation for bone metastases not only relieves
pain but also improves quality of life.
Caissie A, Nguyen J, Sahgal A, Culleton S, Zhang L, Zeng L, Tsao M, Barnes E, Danjoux
C, Chow E. Bone metastases response to palliative radiation associated with improved
BM22 and C15 symptom and quality of life scores.
Khan L, Holden L, Zhang L, Culleton S. Zeng L, Jon F, Wong K, Danjoux C, Tsao M,
Sahgal A, Barnes E, Chow E. Prevalence of sleep disturbance in patients with bone
metastases attending an outpatient radiotherapy clinic.
Sahgal A, Ma L, Weinberg V, Gibbs I, Chao S, Chang U-K, Werner-wasik M, Angelov L,
Chang E. Re-irradiation spinal cord tolerance.
Canadian Orthopaedic Association Meeting. Edmonton, Alberta, Canada, June 20,
2010.
Malempati H, Kreder H, Wadey V, Massicotte E, Yee A. Spine Surgery Fellowship
Training: An evaluation of cognitive and technical competences.
Zahrai A, Chahal J, Stojimirovic D, Schemitsch E, Yee A, Kraemer W. Quality of life and
educational benefit among orthopaedic surgery residents: A prospective multi-centre
comparison of the night float and the standard call systems.
Canadian Spine Society 10th Annual Meeting. Lake Louise, Alberta, Canada, March
11 - 13, 2010.
Malempati H, Kreder H, Wadey V, Massicotte E, Yee A. Orthopaedic and neurosurgical
spine fellowship training: An evaluation of cognitive and technical competences.
Rampersaud R, Lewis S, Mohamed N, Davey R, Gandhi R, Wai E, Fisher C, Alexander D,
Oxner W, Bred A, Yee AJ, Finkelstein JA, Dvorak M. Post-operative improvement in
health related quality of life: A national comparison of surgical treatment for focal (1-2
level) lumbar spinal stenosis compared to total joint replacement for arthritis.
Rampersaud R, Lewis S, Wai E, Fisher C, Alexander D, Oxner W, Bred A, Yee AJ,
Finkelstein JA, Dvorak M. Health related quality of life following decompression
compared to decompression and fusion for degenerative spondylolisthesis: A Canadian
multicenter study.
Zahrai A, Palda V, Davis A, Yee A. The development of a preliminary preoperative
education tool for patients undergoing lumbar microdiscectomy utilizing multiple
stakeholder interview.
EORTC QLG Meeting. Rome, Italy, April 8 - 9, 2010.
Holden L, Chow E. Bone and brain metastases modules.
31
Holden L. Development of a quality of life (QOL) module for malignant spinal cord
compression (MSCC): Preliminary results for Phase I. Holden L. The EORTC Quality of Life Bone Metastases Modules update. Holden L. The EORTC Quality of Life Brain Metastases Module update. Holden L. The EORTC Quality of Life Modules for Bone Metastases and Brain Metastases.
MASCC/ISOO 2010 International Symposium. Vancouver, British Columbia,
Canada, June 24 – 26, 2010.
Caissie A, Holden L, Sahgal A, Culleton S, Zhang L, Chow E. Pre-treatment BN20+2 and
C15-PAL symptom and quality of life scores in patients with brain metastases.
Caissie A, Nguyen J, Holden L, Sahgal A, Zhang L, Chow E. Response to palliative
radiation of bone metastases associated with improved BM22 and C15-PAL symptom and
quality of life scores.
Culleton S, Mitera G, Zhang L, Presutti R, Swaminath A, Chow E. Patient expectations
and understanding of palliative radiotherapy treatment at a rapid response radiotherapy
clinic: A quantitative survey.
Culleton S, Salvo N, Zhang L, Leung M, Khan L, Presutti R, Nguyen J, Holden L, Zeng L,
Chow E. Predictive factors for anxiety and depression in advanced cancer patients.
Khan L, Culleton S, Zhang L, Salvo N, Chow E, Holden L. Comparing symptom severity
and demographics between two time periods in an outpatient palliative radiotherapy
clinic.
Khan L, Mitera G, Probyn L, Ford M, Zhang L, Chow E. Inter-rater reliability between
musculoskeletal radiologists and orthopaedic spinal surgeons on CT imaging features of
spinal metastases.
Nguyen J, Chow E, Zhang L, Culleton S, Holden L, Sahgal A. Palliative response and
functional interference outcomes using the brief pain inventory for spinal bony
metastases with conventional radiotherapy.
Nguyen J, Hayter C, Wong R, Danjoux C, Peltier J, Holden. A survey to assess patients
and patient awareness and interest in hypnosis for cancer pain and distressing
procedures.
University of Toronto Research Day. Toronto, Ontario, Canada, May 8, 2010.
Foote M, Massicotte EM, Sahgal A. Stereotactic body radiotherapy for spine metastases:
a novel approach following minimal access spine surgery.
Khan L, Holden L, Zhang L, Culleton S, Zeng L, Jon F, Wong K, Danjoux C, Tsao M,
Chow E. Prevalence of sleep disturbance in patients with bone metastases attending an
outpatient radiotherapy clinic.
Ruschin M, Nayebi N, Tamerou M, Li W, Sahgal A, Cho Y-B, Menard C, Jaffray D. Cone-
beam CT based evaluation of a novel head frame for intra-cranial stereotactic
radiotherapy. University of Toronto Annual Research Day, Toronto, Ontario, 2010.
32
Abstracts, Poster and Peer-reviewed Presentations
Akens M, Won E, Wise-Milestone L, Wilson B, Yee A, Whyne CM. Effect of photodynamic
therapy on breast cancer metastases in vertebrae of rats pre-treated with bisphosphonates.
(Poster) Orthopaedic Research Society Annual Meeting, New Orleans, Louisiana, March 5-9,
2010.
Akens M, Won E, Wise-Milestone L, Wilson BC, Yee AJM, Whyne CM. Outcome of
photodynamic therapy on breast cancer metastases in vertebrae of rats pre-treated with
bisphosphonates. Canadian Orthopaedic Association Annual Meeting, Edmonton, Alberta, June
18, 2010.
Cho Y, van Prooijen M, Tamerou M, Ruschin M, Zadeh G, Sahgal A, Laperriere N, Jaffray D,
Menard C. Implementation of hypofractionated and adaptive radiotherapy for large brain
metastases using a relocatable head frame on gamma knife perfexion. 15th International
Meeting of the Leksell Gamma Knife Society, Athens, Greece, May 16-20, 2010.
Cusimano MD, Schwartz M, Menard C, Hodaie M, Tsao M, Sahgal A, Zadeh G, Gentili F,
Michaels M, Bernstein M, Kondziolka D. Secondary trigemnial neuralgia and gamma knife: a
series and discussion. 15th International Meeting of the Leksell Gamma Knife Society, Athens,
Greece, May 16-20, 2010.
D‘Souza N, Loblaw DA, Mamedov A, Holden L, Sugar L. Prostate cancer pathology audits: Is
central pathology review still warranted? Genitourinary Cancers Symposium, San Francisco,
California, USA, March 5-7, 2010.
Dennis K. ―A pain in the back at the RRRP‖. Rapid Response Radiotherapy Program Quality
Assurance Rounds, Odette Cancer Centre, Toronto, Ontario, October 19, 2010.
Dennis K. ―Radiation-Induced nausea and vomiting: Variations on a theme‖. Odette Cancer
Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, October 21, 2010.
Dennis K. MR-Guided HIFU for the palliation of painful skeletal metastases: A pilot study.
Rapid Response Radiotherapy Program Educational Rounds. Odette Cancer Centre, Toronto,
Ontario, December 7, 2010.
Dennis K. Palliative radiotherapy: A Canadian perspective‖. Invited Speaker (Representative
for Canada). ASTRO Satellite Symposium: Coordinating the care of patients with advanced
cancer worldwide: Bridging the connection between palliative medicine specialists and
radiation oncologists. A worldwide perspective on palliative radiation oncology. The Institute
for Palliative Medicine at San Diego Hospice, San Diego, California, USA, October 30, 2010.
Emmenegger U, Berry SR, Booth C, Sridhar SS, Winquist E, Bandali N, Chow A, Kerbel RS, Ko
YJ. A phase II study of maintenance therapy with temsirolimus (TEM) after response to first-
line docetaxel (TAX) chemotherapy in castration-resistant prostate cancer (CRPC). ASCO
Genitourinary Cancers Symposium 2011, Orlando, Florida, USA, February 15-17, 2010.
Emmenegger U, Sridhar SS, Booth CM, Kerbel RS, Berry SR, Ko YJ. A phase II study of
maintenance therapy with temsirolimus (TEM) after response to first-line docetaxel (TAX)
chemotherapy in castration-resistant prostate cancer (CRPC). ASCO Annual Meeting 2010.
Journal of Clinical Oncology 28:15s, 2010 (suppl; abstr TPS246).
Emmenegger U. Antivascular Tumor Therapy. 2nd Molecular Oncology and Basic Sciences
Weekend, OncologyEducation.ca, Niagara-on-the-Lake, Ontario, July 10, 2010.
33
Emmenegger U. Antivascular tumor therapy. Basic Sciences Series IV: Angiogenesis, Hospital
for Sick Children, Toronto, Ontario, August 18, 2010.
Emmenegger U. Avascular necrosis of femoral head in patient with castration-resistant
prostate cancer. Rapid Radiation Response Program/Bone Metastasis Clinic (RRRP/BMC)
Research Rounds, Sunnybrook Odette Cancer Centre, Toronto, Ontario, October 19, 2010.
Emmenegger U. Castration-refractory prostate cancer. Medical Oncology Training Program
Orientation Week (University of Toronto), Toronto, Ontario, July 6, 2010.
Emmenegger U. Highlights from ASCO 2010: Prostate cancer update. Regional Medical
Oncologist CME (Amgen Inc.), Toronto, Ontario, June 22, 2010.
Emmenegger U. Systemic therapy update on castration-refractory prostate cancer. Regional
Urological Oncology CME (AstraZeneca Inc.), Toronto, Ontario, October 6, 2010.
Finkelstein J. 1) Orthopaedic Trauma, 2) Spine Trauma, 3) Metastatic Disease. Ecuador
Orthopaedic Society, Quito, Ecuador, April 19 - Apr 23, 2010.
Finkelstein J. Spine Surgery. Response Shift Think Thank, Boston, Massachusetts, USA,
September 19 - September 21, 2010.
Harsha Malempati (trainee presentation), Veronica Wadey, Hans Kreder, David Backstein, Eric
Massicotte, Albert Yee: Spine surgery fellowship training: A review of cognitive and technical
competencies. (Poster) 36th Annual Gallie Day, University of Toronto, Department of
Surgery, Toronto, Ontario, May 7, 2010.
Hojjat SP, Whyne CM: Automated Quantitative Analysis of Metastatic Disease in Rat Spine:
The Effects of Stereological Model and Spatial Resolution. Canadian Orthopaedic Association
Annual Meeting, Edmonton, Alberta, Jun 17, 2010.
Hojjat SP, Whyne CM. Automated quantitative analysis of metastatic disease in rat spine: The
effects of stereological model and spatial resolution. 18th Annual Symposium on
Computational Methods in Orthopaedic Biomechanics, New Orleans, Louisiana, USA, March 5,
2010.
Holden L. Interprofessional Collaboration in the RRRP/BMC. IPE (Interprofessional Education
course), Odette Cancer Centre, Toronto, Ontario, 2010.
Holden L. Lung mets, superior vena cava obstruction and liver mets. Department of Radiation
Oncology Master‘s Students,
Holden L. Percutaneous vertebroplasty. Department of Radiation Oncology Master‘s Students,
Odette Cancer Centre, Toronto, Ontario, 2010.
Holden L. The EORTC Quality of Life Bone, Brain and SCC Metastases module updates. RRRP
Meeting, Odette Cancer Centre, Toronto, Ontario, May 2010.
Holden L. Update on the development of the EORTC bone, brain and SCC modules. RRRP
Rounds, Odette Cancer Centre, Toronto, Ontario, 2010.
Hyde D, Lochray F, Sahgal A. Stereotactic body radiation therapy of the spine using he elekta
synergy, hexapod and BodyFIX systems. Radiotherapy and Oncology 96(2): S18, 2010.
34
Kreder M, Wright D, Whyne CM, Kreder H, Lubovsky O. Prognosticating acetabular fractures
using CT analysis. (Poster) Orthopaedic Research Society Annual Meeting, New Orleans,
Louisiana, March 5-9, 2010.
Larson D, Ma L, Barani I, Sahgal A, Descovitch M, Chuang C, Kunwar S, Petti P. Apparatus
dependent normal tissue dose for radiosurgery of multiple brain metastases. 15th
International Meeting of the Leksell Gamma Knife Society, Athens, Greece, May 16-20, 2010.
Leckie A, Akens M, Woodhouse K, Yee A, Whyne C. Mechanical evaluation of a novel nucleus
pulposus replacement material in health porcine discs. (Poster) 36th Annual Gallie Day,
University of Toronto, Department of Surgery, Toronto, Ontario, May 7, 2010.
Leckie A, Akens M, Woodhouse K, Yee A, Whyne C. Mechanical evaluation of a novel nucleus
pulposus replacement material in health porcine discs. (Poster) Canadian Connective Tissue
Conference, 16th Annual Meeting, Toronto, Ontario, June 4-5, 2010.
Li W, Sahgal A, Foote M, Millar B, Jaffray D, Letourneau D. Impact of immobilization on intra-
fraction motion for spine stereotactic body radiotherapy (SBRT) using cone-beam CT (CBCT).
International Journal of Radiation Oncology, Biology and Physics 78(3): S775, 2010.
Li W, Sahgal A, Foote M, Millar B-A, Jaffray D, Letourneau D. Impact of immobilization on
intra-fraction motion for spine stereotactic body radiotherapy (SBRT) using cone-beam CT
(CBCT). Radiotherapy and Oncology 96(2): S32, 2010.
Ma L, Hu W, Sahgal A, Larson DA. Effect and optimization of beam delivery sequence for
consistent biological effective dose realization in stereotactic radiosurgery treatments.
American Association of Physics in Medicine, Philadelphia, Pennsylvania. Medical Physics
37(6): SU-DD-A2-06, 2010.
Ma L, Sahgal A, Hwang A, Hu W, Chuang c, Descovich M, Larson DA. A two-step optimization
technique for planning multi-target treatments with robotic radiotherapy. American
Association of Physics in Medicine, Philadelphia, Pennsylvania. Medical Physics 37(6): SU-GG-
T-510, 2010.
Malempati H, Kreder H, Wadey V, Massicotte E, Yee A. Spine surgery fellowship training: An
evaluation of cognitive and technical competences. Canadian Orthopaedic Resident's
Association, Edmonton, Alberta, June 18, 2010.
Malempati H, Wadey V, Kreder H, Backstein D, Massicotte E, Yee A. Spine surgery fellowship
training: A review of cognitive and technical competencies. Scientific Day 2010, Institute of
Medical Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, May 5, 2010.
Nayebi N, Ruschin M, Li W, Ménard C, Sahgal A, Jaffray D. Evaluation of inter-fraction setup
uncertainty of the cervical spine using a novel reloxatable head frame intended for intra-
cranial stereotactic radiotherpay. American Association of Physics in Medicine, Philadelphia,
Pennsylvania. Medical Physics 37(6): WE-C-BRA-01, 2010.
Pezeshki P, Akens M, Whyne C, Yee A. Application of cooled radiofrequency in a pre-clinical
metastasis model. 36th Annual Gallie Day, University of Toronto, Department of Surgery,
Toronto, Ontario, May 7, 2010.
Pezeshki P, Akens M, Whyne CM, Yee AJ. Application of cooled radiofrequency in a pre-clinical
metastasis model. (Poster) Canadian Connective Tissue Conference, 16th Annual Meeting,
Toronto, Ontario, June 4-5, 2010.
35
Ruschin M, Nayebi N, Li W, Cho Y, Sahgal A, Menard C, Jaffray D. Assessment of cervical
spine positioning and immobilization accuracy using a novel relocatable head frame intended
for intra-cranial stereotactic radiotherapy. International Journal of Radiation Oncology,
Biology and Physics 78(3): S138, 2010.
Sahgal A, Barani I, Novotny J, Zhang B, Petti P, Larson D, Ma L. Prescription dose guideline
based on physical criterion for multiple metastatic brain tumors treated with stereotactic
radiosurgery. 15th International Meeting of the Leksell Gamma Knife Society, Athens, Greece,
May 16-20, 2010.
Sahgal A, Ma L, Weinberg V, Gibbs I, Chao S, Chang U, Werner-wasik M, Fowler J, Wong S,
Larson D. Human spinal cord re-irradiation guidelines for stereotactic body radiotherapy.
International Journal of Radiation Oncology, Biology and Physics 78(3): S285, 2010.
Sahgal A, Ma L, Weinberg V, Gibbs I, Chao S, Chang U-K, Werner-wasik M, Angelov L, Chang
E. Re-irradiation spinal cord tolerance. Radiotherapy and Oncology 96(2): S34, 2010.
Sahgal A. Critical remarks on spine radiosurgery. 15th International Meeting of the Leksell
Gamma Knife Society, Athens, Greece, May 16-20, 2010.
Sahgal A. Poster discussant for the Radiation Oncology Research Day. University of Toronto,
Toronto, Ontario, 2010.
Sahgal A. Radiation for brain tumors. University of Toronto Neuroradiology Program
Professor‘s Rounds, Toronto, Ontario, 2010.
Sahgal A. Requirements for stereotactic body radiotherapy. McMaster University, Hamilton,
Ontario, 2010.
Sahgal A. Spinal cord tolerance for spine stereotactic body radiotherapy. Department of
Radiation Medicine Rounds, University of Toronto, Toronto, Ontario, 2010.
Sahgal A. Spine Radiosurgery. IMRT Insights: Transforming practice through collaboration.
Target Insights IV, Cancer care Ontario, Toronto, Ontario, 2010.
Sahgal A. Spine SBRT and minimal access spine surgery. PMH Innovation Rounds. University
of Toronto, Toronto, Ontario, 2010.
Sahgal A. Spine stereotactic body radiotherapy: A high dose approach for radioresistant
tumors. Melanoma Rounds, Odette Cancer Centre, University of Toronto, Toronto, Ontario,
2010.
Sahgal A. Stereotactic radiosurgery for brain metastases and neurocognition. 2010 William S.
Keiths lectureship day, University of Toronto, Division of Neurosurgery, University of Toronto,
Toronto, Ontario, 2010.
Sahgal A. Stereotactic radiosurgery for recurrent spine tumors. University of California San
Francisco Update: Management of Recurrent Disease. San Francisco, California, USA, 2010.
Sahgal A. The management of brain metastases in 2010. Department of Radiation Medicine
Oncology Rounds, University of Toronto, Toronto, Ontario, 2010.
Sahgal A. The management of brain metastases in 2010. Oncology Grand Rounds, Odette
Cancer Centre, University of Toronto, Toronto, Ontario, 2010.
36
Sahgal A. The management of brain metastases in 2010. Sunnybrook Health Sciences Centre,
Division of Neurology Grand Rounds, University of Toronto, Toronto, Ontario, 2010.
Sahgal A. The management of brain metastases. Melanoma Rounds, Odette Cancer Centre,
Toronto, Ontario, 2010.
Sahgal A. The management of brain metastases. Southlake Regional Cancer Centre Oncology
Rounds, Newmarket, Ontario, 2010.
Sahgal A. The management of malignant epidural spinal cord compression. Southlake
Regional Cancer Centre Oncology Rounds, Newmarket, Ontario, 2010.
Sahgal A. The treatment of paraspinal disease. Image-guided radiotherapy education course.
Princess Margaret Hospital, University of Toronto, Toronto, Ontario, 2010.
Sousa BA, Buckman RA, Clemons M, Dent SF, Wong NS, Kerbel RS, Sutherland DJ,
Emmenegger U, Gardner S, Pritchard KI. Phase I/II trial of metronomic chemotherapy with
daily dalteparin and cyclophosphamide, twice-weekly methothrexate, and daily prednisone
(DalCMP) as therapy for metastatic breast cancer (MBC). ASCO Annual Meeting 2010. Journal
of Clinical Oncology 28: 15s, 2010 (suppl; abstr 1152).
Weidong Du W, Yang BB, Yang BL, Deng Z, Shan S, Shatseva T, Fang L, Seth A, Yee A.
Versican G3 domain enhances breast cancer self renewal. (Poster) Canadian Connective
Tissue Conference, 16th Annual Meeting, Toronto, Ontario, June 4-5, 2010.
Weidong Du W, Yang BB, Yang BL, Deng Z, Shan S, Shatseva T, Fang L, Seth A, Yee A.
Versican G3 domain enhances breast cancer self renewal. (Poster) Canadian Orthopaedic
Association Annual Meeting, Edmonton, Alberta, June 17-20, 2010.
Wise-Milestone L, Akens M, Grynpas M, Yee A, Wilson B, Whyne C. Bone quality
characterization of a novel preclinical model of mixed osteolytic/osteoblastic vertebral
metastasis. (Poster) 36th Annual Gallie Day, University of Toronto, Department of Surgery,
Toronto, Ontario, May 7, 2010.
Wise-Milestone L, Whyne CM. Local treatment of mixed osteolytic/osteoblastic spinal
metastases: Is photodynamic therapy effective? (Poster) 10th International Conference on
Cancer-Induced Bone Disease, Sheffield, United Kingdom, September 22-25, 2010.
Wise-Milestone L, Won E, Akens M, Yee A, Wilson B, Whyne CM. The effect of photodynamic
therapy on structural integrity and skeletal remodelling of metastatically involved vertebrae,
alone and subsequent to bisphosphonate treatment. BONUS, Ottawa, Ontario, April 8, 2010.
Wise-Milestone L, Yeung C; Akens MK, Whyne CM. Understanding the effects of photodynamic
and radiation therapies on bone: Characterizing osteoblast response. (Poster) Canadian
Orthopaedic Research Society, Edmonton, Alberta, June 17-20, 2010.
Won E, Wise-Milestone L, Akens M, Burch S, Yee A, Wilson B, Whyne CM. Photodynamic
therapy: Tumor cell destruction and augmentation of structural integrity in the spine.
(Poster) Orthopaedic Research Society Annual Meeting, New Orleans, Louisiana, March 5-9,
2010.
Won E, Wise-Milestone L, Akens M, Burch S, Yee AJ, Wilson BC, Whyne CM. Beyond
bisphosphonates: Structural effects of photodynamic therapy on healthy and metastatically
involved vertebrae. (Poster) Orthopaedic Research Society Annual Meeting, New Orleans,
Louisiana, March 5-9, 2010.
37
Yee A. Do patient expectations relate to functional outcome following lumbar spinal surgery.
2010 Orthopaedic: Acute Care & Beyond Conference, Sunnybrook Health Sciences Centre,
Toronto, Ontario, April 9, 2010.
Yee A. Fundamentals of spine surgery: Anterior approaches to the thoracci and lumbar
spines and anterior instrumentation. U of T Spine Program; Inaugural Fellows Course (Chair:
Dr. S. Lewis); 'Fundamentals of Spine Surgery: An Introductory Course of Advanced Spinal
Techniques for Spine Fellows', Toronto, Ontario, August 6, 2010.
Yee A. Integration of Research with Clinical Practice -- Perspectives from Mid Career. Canada
and The United States Bone and Joint Decade: Young Investigators Initiative, Toronto,
Ontario, October 21-31, 2010
Yee A. Spinal injury in polytraumatized patients. From Hospital to Home - The Continuum of
Care after SCI (Joint Venture of: SHSC, UHN, Canadian Paragplegic Association Ontario),
Toronto, Ontario, January 21, 2010.
Yee A. The UT-SpineLINK Collaborative --Creation of a collaborative model to enhance the
triage and care of acute spine patients. Ministry of Health and Long Term Care -- Innovation
Fund Provincial Oversight Committee, Toronto, Ontario, November 18, 2010.
Yee A. Tumor-specific expression of versican / PG-M G3 domain promotes breast cancer cell
invasion and bone metastasis (William Du -- PhD Candidate Trainee Presentation). U of T,
Division of Orthopaedics Annual Research Day, Toronto, Ontario, October 20, 2010.
Yee AJ, Fehlings MG, Malempati H, Fawaz K, Singh A, Ginsberg H, Ahn H, Rice K, Webster F.
UT Spine Program: The UT-SpineLINK collaborative - creation of collaborative model to
enhance the triage and care of acute spine patients. (Poster) Ministry of Health and Long
Term Care -- Innovation Fund Provincial Oversight Committee, Innovation Fund Showcase,
Toronto, Ontario, Nov 18, 2010.
Zahrai A, Chahal J, Stojimirovic D, Schemitsch E, Yee A, Kraemer W. Quality of life and
educational benefit among orthopaedic surgery residents: A prospective multi-centre
comparison of the night float and the standard call systems. Canadian Orthopaedic
Resident's Association, Edmonton, Alberta, June 18, 2010.
Zahrai A, Chahal J, Stojimirovic D, Schemitsch E, Yee A, Kraemer W. Quality of life and
educational benefit among orthopaedic surgery residents: A prospective multi-centre
comparison of the night float and the standard call systems. (Poster) 36th Annual Gallie Day,
University of Toronto, Department of Surgery, Toronto, Ontario, May 7, 2010.
Zahrai A, Palda V, Davis A, Yee A. The development of a preliminary preoperative educational
tool for patients undergoing lumbar microdiscectomy using multiple stakeholder interviews.
(Poster) 36th Annual Gallie Day, University of Toronto, Department of Surgery, Toronto,
Ontario, May 7, 2010.
Zahrai A, Palda V, Davis A, Yee A. The development of a preliminary preoperative educational
tool for patients undergoing lumbar microdiscectomy using multiple stakeholder interviews.
(Poster) Canadian Orthopaedic Association Annual Meeting, Edmonton, Alberta, June 17-20,
2010.
38
APPENDIX A
Rapid Response Radiotherapy Palliative Clinics
http://www.sunnybrook.ca/content/?page=2341
Staff: Dr. E. Chow (Rad Onc), Dr. C. Danjoux (Rad Onc), Dr. M. Tsao (Rad Onc),
Dr. T. Barnes (Rad Onc), Dr. A. Sahgal (Rad Onc), L. Holden (RT), F. Jon (RT).
Objective:
Provide expedited access for symptom relief from incurable cancers in patients with limited life
expectancies.
Eligible Patients:
Symptomatic cancer (any disease site) where palliative radiotherapy may be indicated.
Patients with life expectancies of <6 months.
A ―most responsible physician‖ available to provide follow-up and ongoing oncological care
upon completion of the RRRP consultations.
Ineligible Patients:
1. Candidates for potentially curative treatments.
2. Patients requiring further investigations before radiotherapy opinion can be rendered.
3. Patients who are currently actively being followed by a radiation oncologist at
OCC (unless otherwise specifically arranged).
4. Patients whose disease status is better served by a radiation oncologist who could provide
longitudinal follow-up.
5. Off-service in-patients who require transfer of care to radiation oncology for ongoing oncological
care.
Monday Dr. T. Barnes Sim 4
Tuesday Dr. M. Tsao Sim 4
Wednesday Dr. C. Danjoux Sim 4
Thursday Dr. E. Chow Sim 4
Friday Dr. M. Tsao Sim 4
To make a referral:
1. Fill out an e sheet when requesting a referral to the RRRP clinic.
2. Contact the RRRP nurse.
3. Contact one of the RRRP physicians directly.
39
APPENDIX B
Decision Tree for Patients Referred to RRRP / BMC (January 2001)
Yes No
No
Yes No
Yes
Refer to his / her Rad Onc
To site group based on diagnosis
- lung
- breast - GU etc.
Emergency Urgent Elective < 24 h <1 week Book next available RRRP slot
(Cord Compression (Bleeding, Do not book beyond 2 weeks SVCO) SOB)
No Yes
YES YES
No
** RRRP Policy circulated as addendum to Minutes of Radiation Oncology staff meeting of March 2
nd 2000.
Is patient new to TSRCC?
Did patient see a TSRCC Rad Onc?
Is patient estimated
survival greater than 6 months?
What is the urgency of
appointment?
Is RRRP slot available?
Discuss with RRRP Rad Onc who has a clinic for that day or next few days. Is RRRP Rad Onc able to see patient?
overbook patient to Rad Onc in RRRP inform ref MD and patient
Refer to Rad Onc on call
40
APPENDIX C
Jan 1999: Initiated Bone Metastases Clinic (BMC)
A bi-weekly Bone Metastases Clinic (BMC) was initiated at the OCC on January 8, 1999. The clinic
is staffed by Orthopaedic Surgical Oncologists: Drs. T. Axelrod, J. Finkelstein, D. Stephen,
M. Ford and A. Yee; Radiation Oncologists: Drs. E. Chow, C. Danjoux, M. Tsao, T. Barnes;
Radiation Therapists.
The BMC is held on the 2nd and 4th Friday morning of each month in clinic C at the OCC.
The goals of the BMC are to:
Provide an elective orthopaedic consultation service for patients with bone metastases
referred by OCC oncologists; provide elective radiation oncology consultations to patients
with bone metastases referred by SWHSC physicians.
Provide elective orthopaedic and radiation oncology consultations to patients with bone
metastases referred by community physicians.
Provide follow-up to oncology patients after orthopaedic interventions.
Bone Metastases Clinic – 2nd and 4th Friday (Clinic C)
To make a referral:
1. Fill out an e sheet when requesting a referral to the Bone Metastases Clinic.
2. Contact the RRRP nurse or Radiation Therapist.
3. Contact one of the RRRP physicians directly.
41
APPENDIX D
42
APPENDIX D
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
APPENDIX E [Back]
Content of HOT SPOT Newsletter
1999-2010
60
CONTENT AND INSERTS OF HOT SPOT 1999-2010
Vol 1, Issue 1 February 1999
Editor‘s Corner Dr. Gillian Thomas
From the Chief Executive Officer Dr. Ken Shumak
The first RRRP newsletter Dr. Gillian Thomas
Palliative radiotherapy rounds Dr. Ewa Szumacher
New combined bone metastases clinic Drs. Joel Finkelstein, Edward Chow
A phase II trial of palliative radiotherapy for metastatic renal cell carcinoma
Drs. Edward Chow, Padraig Warde
Prospective assessment of symptom palliation for patients attending a rapid response radiotherapy program
Drs. Edward Chow, Cyril Danjoux, Rebecca Wong
The challenge of speedy delivery of pain relief met by the rapid response clinic at T-SRCC
Dr. Ewa Szumacher, Ms. Lou Andersson
The cancer pain and palliative care clinic at T-SRCC Dr. Larry Librach
Research Corner Dr. Rebecca Wong
Vol 1, Issue 2 May 1999
Message from the Chief Executive Officer Dr. Carol Sawka
A note of thanks
Ms. Ruth Connolly,
Dr. Edward Chow
Editor‘s Corner
Differentiating normal grief from clinical depression Dr. Mary Vachon
Ontario Drug Benefit (ODB) Formulary Changes Ms. Trudi Schueller
Surgical management of metastatic spine disease Dr. Joel Finkelstein
Radiosurgery for brain metastases Dr. Phillip Davey
Surgical management of metastatic extremity lesions Dr. David Stephen
Highlights in the Multinational Association of Supportive Care Cancer Dr. Rebecca Wong
Insert May 1999
Cancer Related Pain Management (Sponsored by Janssen-Ortho Inc.) Dr. David Warr
Vol 1, Issue 3 August 1999 Referring physicians‘ satisfaction with the RRRP
Ms. Ruth Connolly, Dr. Edward Chow
Preparing the community and health care professionals for new challenges
in palliative care – a new endeavour of the rapid response radiotherapy program
Ms. Lou Andersson, Dr. Ewa Szumacher
Editor‘s Corner
Management of bone metastases with external beam radiotherapy Drs. Ewa Szumacher and Rebecca Wong
Single dose wide field radiotherapy Dr. Cyril Danjoux
Bisphosphonates in palliative care Dr. Sandeep Sehdev
Mitoxantrone and prednisone for hormone refractory prostate cancer Dr. Scott Berry
Research Corner Dr. Rebecca Wong
Insert August 1999
Malignant wound management (Sponsored by Convatec) Dr. Valerie Schultz
Vol 1, Issue 4 November 1999
Bayview Support Network: Ontario‘s first on-site cancer support network Ms. Mridula Sood
Dope and cope: it is no longer enough Dr. Michele Chaban
Editor‘s comment
Psychosocial issues with a cancer diagnosis Dr. Margaret Fitch
Cancer care at York Central Hospital Ms. Jane Anderson
Yee Hong palliative care services: A culturally sensitive approach Dr. Stanley Zheng
Hill House – A Richmond Hill hospice Ms. Ann Gold
61
Charles R.R. Hayter, MD, BA, MA, FRCPC joins T-SRCC
Interview with Russell Goldman, MD, CCFP, palliative care physician with
the Temmy Latner Centre for Palliative Care, Mount Sinai Hospital
Research Corner Dr. Rebecca Wong
Insert November 1999
Bowel Obstruction Dr. Larry Librach
Management of Radiotherapy-Induced Acute Gastrointestinal Toxicities Dr. Rebecca Wong
(Sponsored by Novartis Pharmaceuticals Canada, Inc.)
Vol 2, Issue 1 February 2000
Editor‘s comments Dr. Cyril Danjoux
Advance care planning for people with cancer Dr. Scott Berry
The emotional needs of the person with advanced cancer Dr. Mary Vachon
Historical Vignette: The beginnings of palliative radiotherapy in Canada Dr. Charles Hayter
When does palliative care begin? Dr. Larry Librach
Palliative radiation oncology program at the Princess Margaret Hospital Dr. Andrea Bezjak
Ask the Experts Dr. Rebecca Wong
Research Corner Dr. Rebecca Wong
Insert February 2000
Prevention and treatment of radiation-induced emesis Dr. Rebecca Wong
Prevention and treatment of chemotherapy-induced nausea and vomiting (N&V) - (Sponsored by Glaxo-Wellcome) Mr. Carlo De Angelis
Vol 2, Issue 2 May 2000
From the associate editor‘s desk Dr. Edward Chow
Enhancing culturally sensitive practice when caring for seriously ill patients and their families Dr. Elizabeth Latimer
Quality end-of-life care: What do patients think? Dr. Scott Berry
Family dealing with advanced cancer Dr. Mary Vachon
Percutaneous vertebroplasty / cementoplasty at bone metastases clinic, TSRCC Dr. Edward Chow
Historical Vignette: Dr. Joseph-Ernest Gendreau and the early use of radium Dr. Charles Hayter
Research Corner Dr. Rebecca Wong
Insert May 2000 Accessing palliative care in your community
Ms. Joan Pope,
Ms. Lou Andersson
Vol 2, Issue 3 August 2000 From the editorial board
Dr. Ewa Szumacher, Ms. Ruth Connolly
When the patient of a young child is seriously ill Dr. Mary Vachon
Disclosure Dr. Philip Hebert
Utilization of complementary therapies in palliative care Ms. Ruth Connolly
Historical Vignette: Private radiotherapy in Canada Dr. Charles Hayter
Research Corner - Summer research for the Rapid Response Radiotherapy Program Dr. Rebecca Wong
Andrew Loblaw, MD, FRCPC, joins T-SRCC
Insert August 2000
-Nutrition and cancer
-The ABCs of vitamins and minerals (Supported by Novartis Pharmaceuticals Canada, Inc.) Ms. Elaine Posluns
Vol 2, Issue 4 November 2000
Editor‘s Corner Dr. Rebecca Wong
Report from the ―tri-centre‖ meeting with Dr. William E. Powers Dr. Jackson Wu
Adolescents living with a parent with advanced illness Dr. Mary Vachon
Resources on the Internet for improving end-of-life care – How to get started Dr. Scott Berry
Historical Vignette: Vera Peters: Canadian pioneer in psychosocial oncology Dr. Charles Hayter
Research Corner – Informational needs assessment on patients receiving palliative radiotherapy Dr. Rebecca Wong
62
Seventh Annual Conference – The Science and Art of Pain and Symptom Management
Insert November 2000
Cancer-related fatigue -Supported by an educational grant from Janssen-Ortho Inc. Dr. Rebecca Wong
Vol 3, Issue 1
February 2001 From the associate editor‘s desk Dr. Edward Chow
Dr. Maureen Trudeau Dr. Kathleen Pritchard
Staff stress and suffering Dr. Mary Vachon
Historical Vignette: Cancer care before medicare Dr. Charles Hayter
Pain and symptom management conference
Follow-up for breast cancer Dr. Eva Grunfeld
Research Corner – Shared treatment decision-making Dr. Rebecca Wong
Thank you…
Insert February 2001
-Hormones in Breast Cancer, Metastatic Breast Cancer (Supported by Astra-Zeneca Canada Inc.)
Dr. Maureen Trudeau
-Chemotherapy in Metastatic Breast Cancer Treatment, Treatment of
Systemic Recurrence with Chemotherapy (Supported by Aventis)
Dr. Maureen Trudeau
-Herceptin (Supported by Hoffman LaRoche) Dr. Maureen Trudeau
Vol 3, Issue 2 May 2001
From the guest editor's desk Dr. Charles Hayter
Addressing spiritual needs Dr. Sharon Grant
When the shrink gets cancer and gets spiritually transformed Dr. Mary Vachon
Historical Vignette: The history of hospices Dr. Charles Hayter
Ethics: Caring for patients with different faiths Dr. Scott Berry
Research Corner - Patient expectations Dr. Rebecca Wong
Notice regarding treatment delays...
Insert May 2001
A guide to spiritual care of the caregiver, A guide to spiritual assessment of cancer patients. (Supported by AstraZeneca Canada Inc. and Purdue Pharma)
Dr. Michele Chaban
Vol 3, Issue 3 August 2001
From the editor's desk Dr. Cyril Danjoux
Comfort and stress among cancer caregivers Dr. Eva Grunfeld
On suffering in terminal illness Dr. Mary Vachon
Historical Vignette: The history of morphine Dr. Charles Hayter
Research Corner Dr. Rebecca Wong
Insert August 2001 Palliation in lung cancer
(Supported by AstraZeneca Inc. and Purdue Pharma)
Drs. Andrea Bezjak, Dr. Catherine Heath, Ms. Jane Lea
Vol 3, Issue 4 November 2001
From the guest editor's desk Dr. Andrew Loblaw, Ms. Lori Holden
Survey shows 40% of RRRP patients arrive with missing info: A plea for help
Dr. Charles Hayter, Ms. Ruth Connolly
Finding meaning in life in the face of advancing cancer Dr. Mary Vachon
Historical Vignette: The 50th anniversary of cobalt treatment Dr. Charles Hayter
Tough decisions about funding for new palliative therapies: How do we decide? Dr. Scott Berry
Research Corner Dr. Rebecca Wong
Insert November 2001
Malignant Spinal Cord Compression (Partially supported by Purdue Pharma)
Dr. Andrew Loblaw, Ms. Lori Holden
Vol 4, Issue 1 February 2002 From the editor's desk
Dr. Ewa Szumacher, Ms. Joan Pope
63
Advance notice of the ninth annual conference on the science and art of pain and symptom management
Denial and minimization in advanced cancer Dr. Mary Vachon
Global health ethics and palliative care Dr. Scott Berry
Historical Vignette: The story of Essiac Dr. Charles Hayter
Research Corner Dr. Rebecca Wong
Insert February 2002
Oral health care in the patient with cancer Dr. Trey Petty
Mouth care for radiation patients Dr. Alex Hammond
(Supported by Biotene Canada, Division of Bolton Dental Mfg. Inc.)
Vol 4, Issue 2
May 2002 From the associate editor‘s desk Dr. Edward Chow
New chiefs at TSRCC and University of Toronto Dr. Edward Chow, Dr. Cyril Danjoux
Depression in advanced cancer Dr. Mary Vachon
Historical Vignette: Blood and medicine Dr. Charles Hayter
Hope for a good death Dr. Monica Branigan
Research Corner Dr. Rebecca Wong
Insert May 2002
Anemia in hematology and medical/radiation oncology (Supported by Ortho Biotech)
Dr. Gerard Morton, Dr. Rena Buckstein
Vol 4, Issue 3 August 2002 From the associate editor‘s desk
Ms. Lou Andersson, Dr. Cyril Danjoux
TSRCC pharmacy services Ms. Kim Stefaniuk
The transformation from tragedy into grace in terminal illness – part one Dr. Mary Vachon
Historical Vignette: Plants, poisons and potions: Drug treatments for cancer Dr. Charles Hayter
TSRCC pharmacy assists Third World countries Ms. Kim Stefaniuk
Informed decision-making in palliative care Dr. Scott Berry
Research Corner Dr. May Tsao, Dr. Rebecca Wong
Insert August 2002
Accessing medication
(Supported by Amgen Canada and Abbott Laboratories) Ms. Kim Stefaniuk
Vol 4, Issue 4 November 2002
From the associate editor‘s desk Dr. Edward Chow
Palliative care is not euthanasia Dr. Monica Branigan
The transformation from tragedy into grace in terminal illness – part two Dr. Mary Vachon
Palliative care at the University of Texas M.D. Anderson Cancer Center Dr. Toni Barnes
Historical Vignette: Charles Huggins: The Canadian who discovered hormone therapy for prostate cancer Dr. Charles Hayter
Research Corner Dr. Rebecca Wong
Award of Excellence Dr. Cyril Danjoux
Insert November 2002
Expanded role of hormone therapy as neoadjuvant or adjuvant therapy in
prostate cancer patients undergoing definitive treatment. (Supported by Aventis)
Dr. Richard Choo
Vol 5, Issue 1 February 2003 From the editor‘s desk
Drs. Cyril Danjoux,
Edward Chow
Congratulations on fifth year Dr. Carol Sawka
Congratulations on fifth year Dr. Peeter Poldre
Suffering, healing and the wounded healer Dr. Mary Vachon
More fifth year congratulations Dr. Shun Wong
Advance care planning – update and practical tips Dr. Scott Berry
Historical Vignette – A century of radiation therapy in Canada Dr. Charles Hayter
Research Corner Dr. Rebecca Wong
64
Insert February 2003
Pain in cancer: The CARE approach Dr. Larry Librach
Vol 5, Issue 2 May 2003 From the guest editor‘s desk
Dr. Charles Hayter,
Ms. Lou Andersson
The role of the social worker in palliative oncology Ms. Magdalene Winterhoff
Reflections on anxiety in confronting advanced cancer Dr. Mary Vachon
Historical Vignette – Spring fever Dr. Charles Hayter
Research Corner Dr. Rebecca Wong
Insert May 2003
Advances and challenges in the management of febrile neutropenia. (Supported by Amgen Canada Inc.)
Dr. Elizabeth J. Phillips
Vol 5, Issue 3 August 2003
From the guest editor‘s desk Dr. Toni Barnes
Lymphoma in the elderly Dr. Tom Kouroukis
Demorarlization in persons with advanced cancer Dr. Mary Vachon
Ethical issues in dealing with demands for ―futile‖ treatment Dr. Scott Berry
Historical Vignette – The history of oxygen therapy Dr. Charles Hayter
Research Corner Dr. Rebecca Wong
Insert August 2003 Advances for end-of-life respiratory care (Supported by Vital Aire) Dr. Chin K. Chung
Vol 5, Issue 4 November 2003
From the guest editor‘s desk Dr. Cyril Danjoux
Referral of patients to the rapid response radiotherapy clinic
Boredom in terminal illness Dr. Mary Vachon
Hot Spot Survey 2003
―No CPR‖ – Talking it over Dr. Scott Berry
Historical Vignette – The Radium Institute of Toronto Dr. Charles Hayter
Research Corner Dr. Andrea Bezjak
Insert November 2003 Androgen ablation for metastatic prostate cancer (Supported by Aventis)
Dr. Richard Choo
Vol 6, Issue 1 February 2004
From the guest editor‘s desk Dr. May Tsao
Brain metastases: The magnitude of the problem and the struggle to improve outcomes Dr. May Tsao
Dignity-conserving care in palliative care Dr. Mary Vachon
When capacity fluctuates, what happens to consent? Ms. Karen Faith
Historical Vignette: The Montreal Neurological Institute Dr. Charles Hayter
Research Corner Dr. Alina Sturdza, Dr. Andrea Bezjak
Insert February 2004
Palliation in patients with metastatic cancer to the brain
Management of brain metastases (Supported by Aventis)
Dr. May Tsao
Vol 6, Issue 2 May 2004
From the guest editor‘s desk Dr. Charles Hayter
Bisphosphonates in cancer Dr. Rebecca Wong
Anger in the person with advanced disease Dr. Mary Vachon
Ethics and SARS: Collateral damage and relationships in health care Ms. Karen Faith
Historical Vignette: Dr. Herbert Bruce: Ontario cancer visionary Dr. Charles Hayter
Research Corner Dr. Jackson Wu, Dr. Edward Chow
Insert May 2004
Use of bisphosphonates in men with hormone refractory prostate cancer Use of bisphosphonates in women with breast cancer
Dr. Scott Berry Dr. Mark Clemons
Vol 6, Issue 3 From the guest editor‘s desk Dr. Cyril Danjoux
65
August 2004 Supportive Care in Cancer Symposium Dr. Cyril Danjoux
Forgiveness in palliative care Dr. Mary Vachon
Making decisions for others Ms. Karen Faith
Survey shows 40% of RRRP patients arrive with missing info: A plea for help
Dr. Charles Hayter, Ruth Connolly
Research Corner Dr. Laura Dawson
Insert August 2004
Rapid Response Radiotherapy Program (RRRP) Review 1996-2003 RRRP Referral Form
Dr. C. Danjoux
Vol 6, Issue 4 November 2004
From the guest editor‘s desk Dr. Edward Chow
The effect of SARS on access to palliative radiotherapy in the RRRP
Dr. Justin Lee, L. Holden, K. Fung,
C. Danjoux, E. Chow, C. Gillies
Reflections on the life and death of Mary Peacock Dr. Mary Vachon
Quality end-of-life care: Role of economics and the moral climate Ms. Karen Faith
Historical Vignette: The Canadian Society for the History of Medicine Dr. Charles Hayter
Research Corner
Dr. Jackson Wu,
Dr. Edward Chow
Insert November 2004
Cannabinoids in medical practice Dr. Vincent Maida
Vol 7, Issue 1 February 2005
From the guest editor‘s desk Dr. Toni Barnes
Treatment of bone metastases with palliative radiotherapy: Patients‘ treatment preferences
Dr. Ewa Szumacher
Parenting teens during a cancer experience Dr. Mary Vachon
Hospital CPR policy: Solution, prevention or band-aid? Ms. Karen Faith
Historical Vignette: Alfred Hardisty: Ontario‘s pioneer in cancer statistics Dr. Charles Hayter
Research Corner Dr. Rebecca Wong
Insert February 2005
Methadone for cancer pain: An analgesic with a difference Dr. Larry Librach
Vol 7, Issue2 May 2005
From the guest editor‘s desk Dr. Edward Chow
The do-not-resuscitate (DNR) order – incidence of documentation in patient charts of patients referred for palliative radiotherapy
Ms. Lou Andersson, Ms. Nicole Bradley
Caught in the middle – mid-life adults with cancer Dr. Mary Vachon
Does culture influence patients‘ and families‘ DNR decision-making?
Ms. L. Andersson,
S. Mary Williams, N. Bradley
Lessons from my dad Ms. Karen Faith
Temmy Latner Centre Update on Palliative Care – Palliative care and children
Mr. Stephen Jenkinson
PROG Rounds Dr. Tanya Berrang
Farewell to Dr. Charles Hayter Dr. Cyril Danjoux
Insert #1 May 2005
Latest advances in antiemetics for radiation therapy and chemotherapy
(Supported by an educational grant from Solvay) Dr. David Warr
Insert #2 May 2005
Novel therapeutics for management for multiple myeloma (Supported by an educational grant from Ortho Biotech)
Dr. Keith Stewart
Vol 7, Issue 3 August 2005
From the guest editor‘s desk Dr. Cyril Danjoux
A survey to asses cancer patients‘ awareness and interest in hypnosis for pain and distressing procedures – A synopsis
Mrs. Lori Holden, Dr. Charles Hayter
Are we making any progress? Reflections on stressors in the Ontario oncology system over the past 30 years Dr. Mary Vachon
Organizational ethics in the eye of the storm: Woodside Hospice and Terri Ms. Karen Faith
66
Schiavo
Temmy Latner Centre Update on Palliative Care – End-of-life care distance
education: An innovative approach to helping physicians to care for palliative patients
Dr. Anita Singh, Ms. Deborah Adams
TSRCC investigates advanced practice radiation therapy roles! Ms. S. Robson, R. Barker, L. Holden
Insert August 2005
A more minimally invasive approach to the treatment of metastatic spine lesions. (Supported by an educational grant from Kyphon)
Dr. Michael Ford
Vol 7, Issue 4 November 2005
From the guest editor‘s desk Dr. May Tsao
What keeps us going in our work? Dr. Mary Vachon
Research ethics and the importance of determining risk Ms. Karen Faith
Temmy Latner Centre Update on Palliative Care – Is terminal sedation ethical?
Dr. Victor Cellarius
Research Corner – Results of three important randomized studies and their clinical implications. Dr. Jackson Wu
Insert November 2005
Management of hormone refractory prostate cancer / Prostate bone
metastases multidisciplinary clinic. (Supported by an educational grant from Novartis)
Dr. Yoo-Joung Ko
Vol 8, Issue 1 February 2006
From the guest editor‘s desk Dr. Edward Chow
Greetings from Cancer Care Ontario Dr. Linda Rabeneck, Dr. Deb Dudgeon
Hope in advanced disease Dr. Mary Vachon
Temmy Latner Centre Update on Palliative Care – Palliative care grand rounds Ms. Deborah Adams
Private clinics providing palliative IV therapies – What are the ethical
issues? Dr. Scott Berry
Helping children and caregivers in fighting cancer – Truth telling in paediatric palliative care. Dr. Christine Newman
Research Corner Dr. Toni Barnes
Insert February 2006
Venous thromboembolism in cancer patients (Supported by an educational grant from Pfizer Canada) Dr. Agnes Y.Y. Lee
Vol 8, Issue 2 May 2006
From the guest editor‘s desk Dr. Cyril Danjoux
Truth-telling at the end of life Dr. Monica Branigan
What students think: Undergraduate students in palliative health care setting Ms. Hannah H. Chiu
Temmy Latner Centre Update on Palliative Care – The educating future physicians for palliative and end-of-life care project (EFPPEC): Developing competencies in medical undergraduates and postgraduates Dr. Larry Librach
Help no wanted? Dr. Margaret Fitch
If symptom clusters exist, how are they relevant to patient care? Dr. Amna Husain
Forgoing nutrition and hydration in children at the end of life: Is it ever justified? Dr. Adam Rapoport
Insert May 2006
Radioimmunotherapies
(Supported by an educational grant from GlaxoSmithKline) Dr. Rena Buckstein
Vol 8, Issue 3 August 2006
From the guest editor‘s desk Ms. Emily Sinclair
Hope, denial and ethics of care Ms. Karen Faith
The role of a child life specialist at the MBWC-CGPC Ms. Ceilidh Eaton Russell
Quality indicators of end-of-life care in Ontario cancer patients Dr. Lisa Barbera
Palliative care consult team: Moving forward Dr. Jeff Myers
16th Annual provincial conference on palliative and end-of-life care Ms. Emily Sinclair
67
Patients‘ and health care professionals‘ perspectives on the most important quality of life issues in bone metastases
Ms. S.Tharmalingam and Ms. Kristin Harris
Interprofessionalism: A culture of caring Dr. Michele Chaban
Insert August 2006
Video/teleconference as a tool to facilitate research and development in palliative radiotherapy – the Canadian model
Kathryn Burrows, Rebecca Wong,
Andrea Bezjak, Jackson Wu, Graeme Duncan, Rajiv Samant, Jim Wright, Frances Wong, and Cyril Danjoux
Vol 8, Issue 4 November 2006
From the guest editor‘s desk Dr. Toni Barnes
Ethics and preparing for pandemic influenza Ms. Karen Faith
Research Column – Symptom control abstracts presented at the annual Canadian Association of Radiation Oncologist (CARO) meeting
Dr. Toni Barnes
Demanding to live Mr. Stephen Jenkinson
Temmy Latner Centre Update on Palliative Care –Tariro (hope) Dr. Sandy Buchman
Communicating with children about dying Ms. Jennifer B. Pond, Ms. Ceilidh E. Russell
Exploring occupational therapy‘s role – Working with palliative clients and their families
Ms. Amy Tymchuk
Insert November 2006
New developments in the treatment of advanced renal cell carcinoma (RCC) (Supported by an educational grant from Pfizer) Dr. Yoo-Joung Ko
Vol 9, Issue 1 February 2007
From the guest editor‘s desk Dr. Lisa Barbera
The alchemy of healing: Are we wired for compassion? Dr. Mary Vachon
Provincial Palliative Care Integration Project (PPCIP): Enhancing the quality of palliative care services
Dr. Deborah Dudgeon and Raquel Shaw
Moxam
Issues in the measurement and management of dyspnea in home
palliative care patients: Who might benefit from oxygen therapy and how should they qualify?
Ms. Erica Moran and
Dr. Amna Husain
Redirecting hope Dr. Christopher
Church
Capacity and consent: Separating fact from fiction Mr. Blair Henry
Temmy Latner Centre Update on Palliative Care – Computerization in palliative care
Dr. Albert Kirshen
Insert Nov 2006
Advances in iron chelation for myelodysplastic syndromes (Supported by an educational grant from Novartis)
Dr. Rena Buckstein
Vol 9, Issue 2 May 2007
From the associate editor‘s desk Dr. Cyril Danjoux
…on the truth of the matter!?! Mr. Blair Henry
Living after cancer: Challenges in being a survivor Dr. Margaret Fitch
Improving communication during the palliative care of children with brain
tumours – learning from experience
Ms. Ceilidh Eaton
Russell
Symptom clusters in cancer patients with bone metastases Ms. Stephanie Hadi, Grace Fan, Linda
Filipczak
New imaging studies in locally advance breast cancer Drs. Gregory Czarnota, Rebecca Dent, Jacqueline Spayne, Maureen Trudeau, Kathleen
Pitchard, Martin Yaffe,
68
Don Plewes, and Peter Burns
The Rapid Access Palliative Radiotherapy Program: New kid in town Dr. Alysa Fairchild
Insert May 2007
Emerging role of chemotherapy in early prostate cancer (Supported by an educational grant from Sanofi-Aventis)
Dr. Rena Buckstein
Vol 9, Issue 3 August 2007
From the editor‘s desk Dr. Edward Chow
Error in health care Dr. Philip Hebert
Edmond and Gloria Odette make landmark investment at Sunnybrook to help fight cancer
Ms. Natalie Chung-Sayers
Suffering, taboos and interventions Dr. Michele Chaban
New initiatives in advance care planning in Canada Dr. Larry Librach
Review of the Rapid Response Radiotherapy Program (RRRP) at the Odette Cancer Centre (OCC)
Dr. Toni Barnes
Insert August 2007
New options for the treatment of moderate pain (Supported by an educational grant from Purdue Pharma)
Dr. Sol Stern
Vol 9, Issue 4 November 2007
From the guest editor‘s desk Dr. May Tsao
What hope can mask: Talking to children about life-threatening illness and death
Ms. Lysa Toye
The role of experience and meaning in clinical ethics Ms. Karen Faith
The role of the therapeutic clown in the care of children with progressive
life-limiting conditions
Ms. Camilla Gryski
Provincial integration project moving forward at Odette Cancer Centre Ms. Martha Wyatt
Update: New options for the treatment of moderate pain Dr. Sol Stern
New research in palliative care Ms. Shannon Ellis, Ms. Linda Wood, Dr. Lorraine Wood
Health care professionals‘ perception of what defines ―meaningful palliative care‖ in a palliative care unit
Ms. Julie Napolskikh, Drs. Jeff Myers, Debbie Selby
Insert #1 November 2007
Update in the management of colorectal cancer (Supported by an educational grant from Sanofi-Aventis)
Dr. Yoo-Joung Ko
Insert #2 November 2007
The evolving role of cannabinoids in supportive oncology (Supported by and educational grant from Bayer Inc.
Dr. Vincent Maida
Vol 10, Issue 1 February 2008
From the guest editor‘s desk Dr. Toni Barnes
Talking to dying patients Dr. Scott Berry
Being ready for pediatric palliative care – a person reflection Dr. Christine Newman
Involvement of family physicians in the care of patients seen in the Rapid Response Radiotherapy Program
Dr. Toni Barnes
Resilience in palliative care Dr. Mary Vachon
The WHO analgesic ladder and new concepts in our understanding of cancer pain – building on the legacy
Dr. Carlo DeAngelis
Development of the Bone Metastases Module to accompany the EORTC
core questionnaire to assess quality of life in patients with bone metastases in future clinical trials
Ms. Amanda Hird
Insert February 2008
Management of invasive fungal infections (IFIs) in immunocompromised patients (Supported by an educational grant from Astellas Pharma Canada, Inc.)
Dr. Jeffrey H. Lipton
Vol 10, Issue 2 May 2008
From the associate editor‘s desk Dr. Cyril Danjoux
Resilience in professional caregivers Dr. Mary Vachon
Are some GIM patients missing a palliative medicine consult when they Drs. Leah Steinberg,
69
might benefit from it? Anita Chakraborty, Niren Shetty
Advanced directives or advanced troubles? Mr. Blair Henry
Advance care planning in pediatric palliative care: Dr we really know what they are asking?
Ms. Maria Rugg
Improving cancer pain control: Helping patients to gain the most benefit
from their medication
Dr. Carlo DeAngelis
Insert May 2008
Sorafenib in the treatment of advanced heptocellular cancer (Supported by an educational grant from Bayer)
Ms. Anne Horgan, Dr. Jennifer Knox
Vol 10, Issue 3 August 2008
From the editor‘s desk Dr. Edward Chow
Only talk about positive things! Dr. Monica Branigan
Decision-making in a family dyad in the context of advanced cancer Ms. Susanna Edwards
Screening for emotional distress: The sixth vital sign Dr. Margaret Fitch
Opioid Dose Equivalency: Part 1 – General Overview Dr. Carlo DeAngelis
Insert #1 August 2008
Secondary prophylaxis of venous thromboembolism (VTE) in cancer patients (Supported by an educational grant from Pfizer)
Dr. Richard Jay
Insert #2 August 2008
Prostate bone metastases clinic (PBMC): A multidisciplinary approach (Supported by an educational grant from Novartis)
Dr. Urban Emmenegger
Vol 10, Issue 4 November 2008
From the guest editor‘s desk Dr. May Tsao
Spine stereotactic body radiotherapy Dr. Arjun Sahgal
Stereotactic body radiation therapy for lung tumours Dr. Patrick Cheung
Disclosure and palliative chemotherapy Dr. Philip Hebert
Determining outcomes for patients with metastatic epidural spinal cord
compression (MESCC): A quality of life and cost-effectiveness study
Dr. Arjun Sahgal, Ms.
Aimee Gallant, Drs. Michael Fehlings, Edward Chow, Joel Finkelstein
Bringing about change Dr. Michele Chaban
Insert November 2008
Smoking cessation and reduction in patients with cancers (Supported by
an educational grant from Pfizer)
Dr. Peter Selby
Vol 11, Issue 1
February 2009 From the guest editor‘s desk Dr. Toni Barnes
Maintaining Ontario‘s blood supply: A fine balancing act Ms. Debbie Lauzon
De Moto Sanquinas (on the movement of blood) Ethics across the spectrum of transfusion
Mr. Blair Henry
Psychosocial aspects of the use of blood products Dr. Mary Vachon Insert February 2009
Myelodysplastic syndromes (Supported by an education grant from Celgene)
Dr. Rena Buckstein
Vol 11, Issue 2 May 2009
From the editor‘s desk Dr. Edward Chow
―Be patient‖: Ethical considerations regarding wait times Ms. Karen Faith
Dying-centred care for the dying Mr. Stephen Jenkinson
Opioid dose equivalency: Part 2 – Changes in opioid route or mode of administration
Dr. Carlo DeAngelis
Integrating continuous quality improvement in a home palliative care program
Ms. Ceilidh Eaton Russell, Mr. Christopher Obwanga, Ms. Natalie Parry, Dr. Amna Husain
Nursing escort for patients attending Rapid Response Radiotherapy
Program (RRRP)
Ms. Lynn Faltl and
Pager Office Nursing Staff
70
Insert
May 2009 Individualizing a cancer pain management strategy: Beyond the basics
(Supported by an education grant from Sanofi-Aventis)
Drs. Carlo DeAngelis,
Jeff Myers Vol 11, Issue 3 August 2009
From the associate editor‘s desk Dr. Cyril Danjoux
Limits of the duty of care: Lessons from the Golubchuk case Dr. Monica Branigan
A multicentre assessment of the adequacy of cancer pain treatment using the Pain Management Index
Ms. Gunita Mitera, Drs. Alysa Fairchild, Rebecca Wong
Opioid dose equivalency: Part 3 – Opioid switching with morphine-like opioids
Dr. Carlo DeAngelis
2009 Annual Hospice Palliative Care Conference Ms. Gunita Mitera Insert #1 August 2009
Chronic lymphocytic leukemia (CLL) (Supported by an education grant from Roche)
Dr. Rena Buckstein
Insert #2 August 2009
Treatment of chemotherapy- and radiotherapy-induced nausea and vomiting (CINV/RINV) (Supported by an education grant from Merck Frosst Canada Ltd.)
Drs. Mark Pasetka, Carlo DeAngelis
Vol 11, Issue 4 November 2009
From the guest editor‘s desk Dr. Arjun Sahgal
A brief primer on scarcity and fairness Dr. Philip Hébert
Are family caregivers an essential component of our health care system? Dr. Michele Chaban
Ethics Centre launches new on-line consult request on Sunnynet! Dr. Sally Bean
Improving data capture and standardization in a home palliative care program
Mr. Christopher Obwanga
Opioid dose equivalency: Part 4 – Dose conversion for transdermal fentanyl and methadone
Dr. Carlo DeAngelis
Insert #1 November 2009
Anti-epidermal growth factors in colorectal cancer (Supported by an education grant from Amgen)
Dr. Yoo-Joung Ko
Insert #2 November 2009
Management of symptomatic side effects of anti-hormonal therapy in breast cancer survivors (Supported by an education grant from Pfizer)
Dr. Christine Simmons
Vol 12, Issue 1 February 2010
From the guest editor‘s desk Dr. May Tsao
Projected referral for health care services in an outpatient palliative radiotherapy clinic
Ms. Roseanna Presutti, Dr. Elizabeth Barnes
Caring and moral distress: Why do I feel so bad? Ms. Karen Faith
An N of one at a time: A little national survey on good death Mr. Stephen Jenkinson
Breakthrough pain – A thorn by any other name would be as sharp Dr. Carlo DeAngelis
Patient and Family Support Program: The first year Drs. Jeff Myers, Margaret Fitch, Ms.
Pat Brown Insert #1 February 2010
Exercise and breast cancer (Supported by an education grant from Pfizer) Dr. Teresa Petrella
Insert #2
February 2010 Targeting RANK-ligand in the treatment of bone metastases (Supported
by an education grant from Amgen)
Dr. Christine
Simmons Insert #3 February 2010
Treatment of chronic lymphocytic leukemia (CLL) in the untreated patient (Supported by an education grant from Roche)
Dr. Martina Trinkaus
Vol 12, Issue 2 May 2010
From the guest editor‘s desk Ms. Lori Holden
Running care team meetings: A primer! Mr. Blair Henry
Providing person-centred cancer care Dr. Margaret Fitch
Predictors of place of death and family caregiver burden across the home-based palliative care trajectory
Drs. Denise Guerriere, Peter Coyte, Amna Husain, Denise Marshall
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Current research on normal and complicated/prolonged grief Dr. Mary Vachon Insert May 2010
Stereotactic body radiotherapy for liver metastases
Surgical resection of colorectal liver metastases: An update (Supported by an education grant from Roche)
Dr. Hans Chung
Dr. Calvin Law
Vol 12, Issue 3 August 2010
From the associate editor‘s desk Dr. Cyril Danjoux
Humane end-of-life treatment conversations Dr. Monica Branigan
New trend: Survivorship care Dr. Margaret Fitch
Dysphasia and pill-taking in the oncology setting Dr. Carlo DeAngelis
2010 Annual Hospice Palliative Care Conference Ms. Florencia Jon
Panic in cancer patients: ―Fight or flight‖ Dr. Eileen La Croix
Sunny side up Mr. Matthew Mendonca
Insert #1 August 2010
Breakthrough cancer pain: Assessment and management challenges
(Supported by an education grant from Valeant Canada Ltd.)
Dr. Lawrence Librach
Vol 12, Issue 4 November 2010
From the editor‘s desk Dr. Edward Chow
Mitigating health care communication barriers: A legal, ethical and economic case for professional medical interpreters
Ms. Sally Bean
Palliative end-of-life home care and Chinese immigrants: The meaning of home and negotiations of care
Drs. Lisa Seto, Jan Angus, Doris Howell, Denise Gastaldo, and Amna Husain
Having and getting more life Dr. Michele Chaban
Opioid-induced hyperalgesia: When more is less Dr. Carlo DeAngelis
The multi-dimensional role of the clinical nutrition team at the Odette
Cancer Centre
Ms. Rosie Benson,
Elaine Posluns, Tracey Rapier, Edith Stokes, and Pauline Wisdom-Gilliam
Insert #1 November 2010
Treatment of chronic lymphocytic leukemia in the elderly
(Supported by an education grant from Roche)
Dr. Matthew Cheung
Insert #2 November 2010
HER2 testing and trastuzumab in advanced gastric and gastroesophageal cancer (Supported by an education grant from Roche)
Drs. Eugene Hsieh, Yoo-Joung Ko
Insert #3 November
2010
Cancer-associated venous thromboembolism NCCN clinical practice
guidelines – Update 2010 (Supported by an education grant from Pfizer)
Dr. Richard Jay
Insert #4 November 2010
Systemic therapy for metastatic Renal Cell Carcinoma (mRCC) (Supported by an education grant from Novartis)
Drs. Sonal Gandhi, Georg Bjarnason
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APPENDIX F [Back]
Undergraduate Teaching – Co-op Program
Programme Student Period
Fourth year student
University of Waterloo
Shaelyn Culleton 2008 - 2010
Third year student
University of Waterloo
Janet Nguyen 2009 – 2010
Second year student
University of Waterloo
Liang Zeng 2010
Third year student
McMaster University
Cassandra Uy 2010
Third year student
University of Western Ontario
Justin Kwong 2010
First year student
McMaster University
Karrie Wong 2010
First year medical student
University of Western Ontario
Esther Chan 2010
Second year student
University of Waterloo
Kaitlin Koo 2010
73
APPENDIX G
[Back]
Ongoing Research Studies in the Rapid Response Radiotherapy Program and the Bone Metastases Clinic
Study Titles
Examining Urinary Markers for Dexamethasone Metabolism, Inflammatory Cytokines and Bone Marker Turnover Following the Decadron Prophylaxis of
Pain Flare
Assessing quality of life in cancer patients receiving palliative radiotherapy for symptomatic lung cancer or lung metastases using the European
Organization for Research and Treatment of Cancer Lung Cancer Module (EORTC QLQ-LC13)
SC-20 A Phase III International Randomized Trial of Single Versus Multiple
Fractions for Re-irradiation of painful bone metastases (NCIC Clinical Trials Group)
SC-20U Effect of Re-Irradiation for bone pain on Urinary Markers of Osteoclast Activity --A companion study to SC 20
International Cross-Cultural Field Validation of an EORTC Questionnaire
Module for Patients with Bone Metastases (EORTC QLQ-BM22)
Examining Urinary Markers of Pain Flare in Patients Undergoing External Beam Radiotherapy in the Treatment of Bone Metastases
International Validation of the European Organization for Research and
Treatment of Cancer Brain Module (EORTC-QLQ-BN20) for Assessing Quality of Life in Patients with Brain Metastases
Assessing Quality of Life in Patients with Bone Metastases Using the
European Organization for Research and Treatment of Cancer Bone
Metastases Module (EORTC QLQ-BM22)
Prospective Analysis of Antiemetic Medication Prescribed for Radiation Induced Emesis for Patients seen in the Rapid Response Radiotherapy
Program (RRRP)
74
Assessing Quality of Life in Patients with Brain Metastases Using the
European Organization for Research and Treatment of Cancer Brain Module (EORTC QLQ-BN20)
Correlating Radiotherapy Response with Tumour Related Factors in Cancer
Patients with Bone Metastases to the Spine
Patient Expectation and Understanding of Palliative Radiotherapy Treatment at the RRRP: A Quantitative Survey
75
APPENDIX H: Report Submission for Knowledge Translation Casebook (in Association with Ontario Institute for Cancer Research, Canadian Partnership Against Cancer,
and McMaster University Health Sciences)
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APPENDIX I
Emily Sinclair Written by Mark Hayes
Chances are you don't know what a Radiation Therapist does. Some people might envision a nurse that takes x-rays or perhaps (if you’re into science fiction), a cross between Darth Vader and Dr. Fraser Crane. According to the National Cancer
Institute, “Radiation therapy is the treatment of cancer and other diseases with ionizing radiation.” The therapist works with doctors, patients and all members of the hospital team to strategize and implement the destruction of malignant cells.
Emily Sinclair has been waging war on cancer for over 20 years. She graduated with a DCR(T) from the School of Radiotherapeutics and Oncology in Glasgow, Scotland. Shortly after graduation, Emily was headhunted by the Canadian Government, as Emily explains, "The wait list for cancer treatment in Canada was too high, so they sent scouts all around the world to bring in new talent." They offered Emily a one year contract and an exciting opportunity to move to a new country and put her new skillset to work. It's been over twenty years and she's still here.
Emily works as a radiation therapist at the Odette Cancer Centre in Toronto's Sunnybrook Hospital. On any given day, she can find herself doing anything from calculating the radiation dose and planning the patient’s treatment, preparing an isodose distribution to spare as much healthy tissue as possible, counselling patients and their families, or treating patients with the high-tech radiation
equipment with names that are near impossible to pronounce. Her role in the patient’s recovery is absolutely essential — remember, the doctor sees a patient once every two weeks, whereas Emily deals with them every day for 6 weeks straight.
Emily is the recipient of multiple awards, but perhaps the most prestigious is a recent Academic Appointment at the University of Toronto's Department of Radiation Oncology within the Faculty of Medicine. She was awarded this honour for her significant contribution and dedication to her field of study; as a result, she contributes to the world of academia by writing manuscripts and lecturing both locally and across the world.
Aside from the obvious challenges Emily faces on a daily basis, she wants to raise awareness to difficulties facing her discipline at large, stating, “The salaries aren’t great, but our qualifications have to be.” Most radiation therapists have at least 7 years of post-secondary education under their belt, but their pay levels don’t represent two degrees, “Many good Radiation Therapists move on to drug companies or medical tech manufacturers — we can’t compete with the salaries they offer.” Through Emily’s efforts with the Canadian Association of Medical Radiation Technologists (CAMRT) and her union the Professional Institute of the Public Service of Canada (PIPSC), she fights for the strength of her profession which ultimately contributes to the betterment of public health and society at large.
http://www.ottawalife.com/index.php?option=com_content&view=article&id=465:emily-
sinclair&catid=74:public-service&Itemid=100018
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