INFLAMMATORY SKIN DISORDERS
eczema
pathophysioilogy exact cause unknown defect of the skin that impairs its function
as a barrier, combined with an abnormal function of the immune system, are believed to be important factors.
Some forms of eczema can be triggered by substances that come in contact with the skin, such as soaps, cosmetics, clothing, detergents, jewelry(contact dermatitis)
common in infants often have a family history of the
condition or allergic conditions as asthmaor hay fever.(atopy
Clinical features Itching Dry reddened skin Blisters/oozing
sites Adults/children- insides of the elbows,
knees, and ankles. In infants - face
management Steroids –local Antihistamines for itching
Contact dermatitis
psoriasis Psoriasis A chronic inflammatory skin disease
characterized by dry pink scaling round patches.
Cause unknownGenatic and env
Disorganized
Neutrophilaccumulation
Immaturity
Proliferation
features Erythematous, raised patches with
silvery scales Symmetric Pruritic/ Painful Pitting Nails Arthritis in 10-20% of patients Sites-extensor surfaces of knee/elbow
Types of psoriasis Chronic plaque psoriasis Erythrodermic Guttae psoriasis Nail pitting pustular
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Chronic Plaque Psoriasis
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Erythrodermic Psoriasis
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Nail changes
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Guttate Psoriasis
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management Difficult to cure Moisturizers Corticosteroids Tar/ vitamin D 3 Drugs for itchinh
acne
Causes? Adolecence
Emotional stress Androgens Family history
Pathogenesis Plugging of the hair
follicle w/ abnormally keratinized
cells
Androgen-induced sebaceous gland hyperactivity
Proliferation of bacteria
Inflammation
management Local applications Antibiotics Oral drugs
urticaria
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Mostly by an allergic reaction Acute urticaria can be treated with
antihistamones
Thank you!
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