Human Intervention Required

TM1387

2636534

MB3864A

Real space molecular replacement, combining MR/MADTM1387, 2.6 A, 8 mols/asu, homolog to 1n3b; MB3864A, 2.7 A, 3 mols/asu, homolog to 1vpm

Combining low resolution phases with high resolution data from different crystals

Non-routine NCS averaging 2636534, 4 mols/asu, 2.7 A, intertwined monomers

Twinning MM4090A, p21 twinning and space group ambiguities

PC06751C

Many heavy atoms PC06751C, 120 Se, 2.7 A, 6 mols/asu

MM4090A

Number of targets with bound ligands of biological significance: 66Number of targets containing a UNknown Ligand (UNL): 28Number of targets containing 2 different ligands of biological significance: 22

FAD or FMN: 3 targetsNAD or NADH: 11 targetsPyridoxal-5'-Phosphate: 5 targetsATP or ADP: 3 targetsCo-A: 3 targetsS-adenosylmethionine or S-adenosylhomocysteine: 4 targets